Rinaldo Bellomo

Summary

Affiliation: University of Melbourne
Country: Australia

Publications

  1. ncbi request reprint Renal replacement therapy in the ICU: the Australian experience
    R Bellomo
    Department of Intensive Care Medicine, Austin and Repatriation Medical Centre, Melbourne, Australia
    Am J Kidney Dis 30:S80-3. 1997
  2. ncbi request reprint Cardiovascular monitoring tools: use and misuse
    Rinaldo Bellomo
    Department of Intensive Care, Melbourne Victoria, Australia
    Curr Opin Crit Care 9:225-9. 2003
  3. pmc Noradrenaline and the kidney: friends or foes?
    R Bellomo
    Department of Intensive Care and Medicine, Austin and Repatriation Medical Centre, Melbourne, Australia
    Crit Care 5:294-8. 2001
  4. ncbi request reprint Blood purification in the intensive care unit: evolving concepts
    R Bellomo
    Austin and Repatriation Medical Centre, Intensive Care Unit, Melbourne, Victoria, Australia
    World J Surg 25:677-83. 2001
  5. ncbi request reprint High protein intake during continuous hemodiafiltration: impact on amino acids and nitrogen balance
    R Bellomo
    Intensive Care Unit, Austin and Repatriation Medical Centre, Heidelberg, Victoria, Australia
    Int J Artif Organs 25:261-8. 2002
  6. ncbi request reprint The Acute Dialysis Quality Initiative--part II: patient selection for CRRT
    Rinaldo Bellomo
    Department of Intensive Care, Austin and Repatriation Hospital, Melbourne, Australia
    Adv Ren Replace Ther 9:255-9. 2002
  7. pmc Continuous haemofiltration in the intensive care unit
    R Bellomo
    Austin and Repatriation Medical Centre, Melbourne, Victoria, Australia
    Crit Care 4:339-45. 2000
  8. ncbi request reprint Indications and criteria for initiating renal replacement therapy in the intensive care unit
    R Bellomo
    Department of Intensive Care, Austin and Repatriation Medical Centre, Melbourne, Australia
    Kidney Int Suppl 66:S106-9. 1998
  9. ncbi request reprint Hemodynamic support and the role of dopamine
    R Bellomo
    Department of Intensive Care Medicine, Austin and Repatriation Medical Centre, Melbourne, Australia
    Kidney Int Suppl 66:S71-4. 1998
  10. ncbi request reprint Who should manage CRRT in the ICU? The intensivist's viewpoint
    R Bellomo
    Department of Intensive Care Medicine, Austin and Repatriation Medical Centre, Melbourne, Australia
    Am J Kidney Dis 30:S109-11. 1997

Collaborators

Detail Information

Publications196 found, 100 shown here

  1. ncbi request reprint Renal replacement therapy in the ICU: the Australian experience
    R Bellomo
    Department of Intensive Care Medicine, Austin and Repatriation Medical Centre, Melbourne, Australia
    Am J Kidney Dis 30:S80-3. 1997
    ..As shown by a recent regional survey, this approach, although somewhat unique, is dominant and appears to work well with excellent clinical results and constant clinical research output...
  2. ncbi request reprint Cardiovascular monitoring tools: use and misuse
    Rinaldo Bellomo
    Department of Intensive Care, Melbourne Victoria, Australia
    Curr Opin Crit Care 9:225-9. 2003
    ..To review important areas of current and novel hemodynamic monitoring practice in the intensive care unit and to highlight potential areas of physiologic and clinical use or misuse, as well as areas of uncertainty and ongoing controversy...
  3. pmc Noradrenaline and the kidney: friends or foes?
    R Bellomo
    Department of Intensive Care and Medicine, Austin and Repatriation Medical Centre, Melbourne, Australia
    Crit Care 5:294-8. 2001
    ..There is no reason to fear the use of noradrenaline. If it is used to support a vasodilated circulation with a normal or increased cardiac output, it is likely to be the kidney's friend not its foe...
  4. ncbi request reprint Blood purification in the intensive care unit: evolving concepts
    R Bellomo
    Austin and Repatriation Medical Centre, Intensive Care Unit, Melbourne, Victoria, Australia
    World J Surg 25:677-83. 2001
    ..The intensivist-surgeon and the general surgeon need to be aware of and understand these developments in extracorporeal therapy if they wish to make the full armamentarium of modern treatment available to their sickest patients...
  5. ncbi request reprint High protein intake during continuous hemodiafiltration: impact on amino acids and nitrogen balance
    R Bellomo
    Intensive Care Unit, Austin and Repatriation Medical Centre, Heidelberg, Victoria, Australia
    Int J Artif Organs 25:261-8. 2002
    ..5 g/kg/day) parenteral amino acid supplementation on nitrogen balance, amino acid losses and azotemic control in a cohort of patients with severe acute renal failure (ARF)...
  6. ncbi request reprint The Acute Dialysis Quality Initiative--part II: patient selection for CRRT
    Rinaldo Bellomo
    Department of Intensive Care, Austin and Repatriation Hospital, Melbourne, Australia
    Adv Ren Replace Ther 9:255-9. 2002
    ..The article offers recommendations for clinical practice based on the findings of the expert group. It also offers suggestions and sets priorities for future research in this important area of critical care nephrology...
  7. pmc Continuous haemofiltration in the intensive care unit
    R Bellomo
    Austin and Repatriation Medical Centre, Melbourne, Victoria, Australia
    Crit Care 4:339-45. 2000
    ..Experimental evidence suggests that this is a promising approach to the management of septic shock in critically ill patients. The evolution and use of CRRT is likely to continue and grow over the next decade...
  8. ncbi request reprint Indications and criteria for initiating renal replacement therapy in the intensive care unit
    R Bellomo
    Department of Intensive Care, Austin and Repatriation Medical Centre, Melbourne, Australia
    Kidney Int Suppl 66:S106-9. 1998
    ..In fact, there are several reasons why a more aggressive approach and an earlier intervention may be justified in the ICU...
  9. ncbi request reprint Hemodynamic support and the role of dopamine
    R Bellomo
    Department of Intensive Care Medicine, Austin and Repatriation Medical Centre, Melbourne, Australia
    Kidney Int Suppl 66:S71-4. 1998
    ..When these measures are adhered to, renal protection and clinical success are a much more likely outcome than when stereotyped approaches are followed...
  10. ncbi request reprint Who should manage CRRT in the ICU? The intensivist's viewpoint
    R Bellomo
    Department of Intensive Care Medicine, Austin and Repatriation Medical Centre, Melbourne, Australia
    Am J Kidney Dis 30:S109-11. 1997
    ..Australian intensivists have taken up CRRT from the start and now control it. Patient outcomes under such a system, as reported here, are above average, and confirm the effectiveness of such an approach...
  11. ncbi request reprint Septic acute kidney injury in critically ill patients: clinical characteristics and outcomes
    Sean M Bagshaw
    Department of Intensive Care and Department of Medicine, Austin and Repatriation Medical Centre, Melbourne, Australia
    Clin J Am Soc Nephrol 2:431-9. 2007
    ..Patients with septic AKI had an increased risk for death and longer duration of hospitalization yet showed trends toward greater renal recovery and independence from RRT...
  12. doi request reprint Timing of renal replacement therapy and clinical outcomes in critically ill patients with severe acute kidney injury
    Sean M Bagshaw
    Department of Intensive Care and Department of Medicine, Austin and Repatriation Medical Centre, Melbourne, Australia
    J Crit Care 24:129-40. 2009
    ..The aim of this study is to evaluate the relationship between timing of renal replacement therapy (RRT) in severe acute kidney injury and clinical outcomes...
  13. doi request reprint Greater increase in urinary hepcidin predicts protection from acute kidney injury after cardiopulmonary bypass
    John R Prowle
    Department of Intensive Care, Austin Hospital, Melbourne, Victoria, Australia
    Nephrol Dial Transplant 27:595-602. 2012
    ..Acute kidney injury (AKI) is a common and serious complication of cardiopulmonary bypass (CPB) surgery. Hepcidin, a peptide hormone that regulates iron homeostasis, is a potential biomarker of AKI following CPB...
  14. ncbi request reprint Long-term effect of a Medical Emergency Team on mortality in a teaching hospital
    Daryl Jones
    Australian and New Zealand Intensive Care Research Centre, Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia
    Resuscitation 74:235-41. 2007
    ..To assess the effect of a Medical Emergency Team (MET) service on patient mortality in the 4 years since its introduction into a teaching hospital...
  15. doi request reprint Novel and conventional serum biomarkers predicting acute kidney injury in adult cardiac surgery--a prospective cohort study
    Anja Haase-Fielitz
    Department of Intensive Care, Austin Health, Melbourne, Australia
    Crit Care Med 37:553-60. 2009
    ..To compare the value of novel with conventional serum biomarkers in the prediction of acute kidney injury (AKI) in adult cardiac surgical patients according to preoperative renal function...
  16. doi request reprint The systemic and regional hemodynamic effects of phenylephrine in sheep under normal conditions and during early hyperdynamic sepsis
    Hiroshi Morimatsu
    Department of Intensive Care, Austin Health, Melbourne, Victoria, Heidelberg, Victoria 3084, Australia
    Anesth Analg 115:330-42. 2012
    ..Phenylephrine treatment of hypotension in sepsis raises concern because it may decrease vital organ bloodflow. Accordingly, we investigated the effects of phenylephrine on systemic and regional bloodflow in normal and septic sheep...
  17. doi request reprint Recent trials in critical care nephrology
    Rinaldo Bellomo
    Department of Intensive Care, Austin Hospital, Melbourne, Vic, Australia, USA
    Contrib Nephrol 165:299-309. 2010
    ....
  18. pmc Very old patients admitted to intensive care in Australia and New Zealand: a multi-centre cohort analysis
    Sean M Bagshaw
    Department of Intensive Care, Austin Hospital, Studley Road, Heidelberg, VIC 3084, Australia
    Crit Care 13:R45. 2009
    ..The primary objective was to evaluate the rate, characteristics and outcomes of very old (age >or= 80 years) patients admitted to intensive care units (ICUs)...
  19. ncbi request reprint Renal blood flow and function during recovery from experimental septic acute kidney injury
    Christoph Langenberg
    Austin and Repatriation Medical Centre, Department of Intensive Care, 3084, Heidelberg, Victoria, Australia
    Intensive Care Med 33:1614-8. 2007
    ..To measure renal blood flow (RBF) and renal function during recovery from experimental septic acute kidney injury (AKI)...
  20. ncbi request reprint Unmeasured anions in critically ill patients: can they predict mortality?
    Jens Rocktaeschel
    Department of Intensive Care, Austin and Repatriation Medical Centre, Melbourne, Australia
    Crit Care Med 31:2131-6. 2003
    ..To determine whether base excess, base excess caused by unmeasured anions, and anion gap can predict lactate in adult critically ill patients, and also to determine whether acid-base variables can predict mortality in these patients...
  21. ncbi request reprint Effects of renal denervation on regional hemodynamics and kidney function in experimental hyperdynamic sepsis
    Paolo Calzavacca
    1Florey Institute of Neuroscience and Mental Health, University of Melbourne, Vic, Australia 2Department of Intensive Care, Austin Health, Heidelberg, Vic, Australia 3Department of Anaesthesia and Intensive Care, AO Melegnano, PO Uboldo, Cernusco sul Naviglio, Italy 4Australian and New Zealand Intensive Care Research Centre, Monash University, Melbourne, Vic, Australia 5Department of Medicine, University of Melbourne, Austin Health, Heidelberg, Vic, Australia
    Crit Care Med 42:e401-9. 2014
    ..To determine the influence of the renal sympathetic nerves on the pathogenesis of septic acute kidney injury...
  22. doi request reprint Pilot double-blind, randomized controlled trial of short-term atorvastatin for prevention of acute kidney injury after cardiac surgery
    John R Prowle
    Department of Intensive Care, Austin Health, Melbourne, Victoria, Australia
    Nephrology (Carlton) 17:215-24. 2012
    ..To test whether short-term perioperative administration of oral atorvastatin could reduce incidence of postoperative acute kidney injury (AKI) in cardiac surgical patients...
  23. ncbi request reprint Prospective controlled trial of effect of medical emergency team on postoperative morbidity and mortality rates
    Rinaldo Bellomo
    Department of Intensive Care and Department of Medicine, Austin and Repatriation Medical Centre, Melbourne, Australia
    Crit Care Med 32:916-21. 2004
    ....
  24. doi request reprint The impact of Rapid Response System on delayed emergency team activation patient characteristics and outcomes--a follow-up study
    Paolo Calzavacca
    Department of Intensive Care, Austin Hospital, Melbourne, Australia
    Resuscitation 81:31-5. 2010
    ..To evaluate the impact of Rapid Response System (RRS) maturation on delayed Medical Emergency Team (MET) activation and patient characteristics and outcomes...
  25. ncbi request reprint Effects of saline or albumin resuscitation on standard coagulation tests
    Rinaldo Bellomo
    Department of Intensive Care, Austin Hospital, Melbourne, Vic
    Crit Care Resusc 11:250-6. 2009
    ..To explore whether fluid resuscitation with normal saline or 4% albumin is associated with differential changes in routine clinical coagulation tests...
  26. pmc Long term effect of a medical emergency team on cardiac arrests in a teaching hospital
    Daryl Jones
    Department of Intensive Care, Alfred Hospital, Commercial Road, Prahran, Melbourne, Victoria 3181, Australia
    Crit Care 9:R808-15. 2005
    ..It is unknown whether the reported short-term reduction in cardiac arrests associated with the introduction of the medical emergency team (MET) system can be sustained...
  27. pmc Decreased catecholamine degradation associates with shock and kidney injury after cardiac surgery
    Anja Haase-Fielitz
    Department of Intensive Care, Austin Health, Melbourne, Australia
    J Am Soc Nephrol 20:1393-403. 2009
    ..In summary, this study identifies COMT LL homozygosity as an independent risk factor for shock, AKI, and hospital stay after cardiac surgery. (ClinicalTrials.gov number, NCT00334009)...
  28. doi request reprint Fluid management in septic acute kidney injury and cardiorenal syndromes
    Rinaldo Bellomo
    Department of Intensive Care, Austin Health, Heidelberg, Melbourne, Vic, Australia
    Contrib Nephrol 165:206-18. 2010
    ..Thus, accurate assessment of fluid status and careful definition of targets are needed to improve clinical outcomes. Controlled studies of conservative versus liberal fluid management in patients with AKI or CRS seem justified...
  29. ncbi request reprint Solute mass balance during isovolaemic high volume haemofiltration
    Shigehiko Uchino
    Department of Intensive Care, Austin and Repatriation Medical Centre, Heidelberg, 3084 Victoria, Australia
    Intensive Care Med 29:1541-6. 2003
    ..To evaluate the effect of changing the amount of pre-dilution replacement fluid on the sieving coefficient (SC) and mass transfer of small solutes during isovolaemic high-volume haemofiltration (HVHF)...
  30. ncbi request reprint Conservative oxygen therapy in mechanically ventilated patients: a pilot before-and-after trial
    Satoshi Suzuki
    1Department of Intensive Care, Austin Hospital, Heidelberg, Vic, Australia 2Australian and New Zealand Intensive Care Research Centre, Melbourne, Vic, Australia
    Crit Care Med 42:1414-22. 2014
    ..To assess the feasibility and safety of a conservative approach to oxygen therapy in mechanically ventilated ICU patients...
  31. doi request reprint Arterial carbon dioxide tension and outcome in patients admitted to the intensive care unit after cardiac arrest
    Antoine G Schneider
    Department of Intensive Care, Austin Hospital, Melbourne, Victoria, Australia
    Resuscitation 84:927-34. 2013
    ..Arterial carbon dioxide tension (PaCO2) affects neuronal function and cerebral blood flow. However, its association with outcome in patients admitted to intensive care unit (ICU) after cardiac arrest (CA) has not been evaluated...
  32. ncbi request reprint The nature and discriminatory value of urinary neutrophil gelatinase-associated lipocalin in critically ill patients at risk of acute kidney injury
    Neil J Glassford
    Department of Intensive Care, Austin Hospital, 145 Studley Rd, Heidelberg, Melbourne, Vic, 3084, Australia
    Intensive Care Med 39:1714-24. 2013
    ..Different molecular forms of urinary neutrophil gelatinase-associated lipocalin (NGAL) have recently been discovered. We aimed to explore the nature, source and discriminatory value of urinary NGAL in intensive care unit (ICU) patients...
  33. ncbi request reprint Stress hyperlactatemia modifies the relationship between stress hyperglycemia and outcome: a retrospective observational study
    Kirsi Maija Kaukonen
    1Australian and New Zealand Intensive Care Research Centre, School of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia 2Department of Anesthesiology and Resuscitology, Okayama University Hospital, Okayama, Japan 3Intensive Care Unit, Geelong Hospital, Barwon Health, Geelong, Australia 4Intensive Care Unit, Austin Health, Heidelberg, Australia 5Division of Pulmonary and Critical Care Medicine, Eastern Virginia Medical School, Norfolk, VA
    Crit Care Med 42:1379-85. 2014
    ..To study the effect of stress hyperlactatemia on the association between stress hyperglycemia and mortality...
  34. ncbi request reprint Phase II, randomized, controlled trial of high-dose N-acetylcysteine in high-risk cardiac surgery patients
    Michael Haase
    Department of Intensive Care, Austin Hospital, University of Melbourne, Australia
    Crit Care Med 35:1324-31. 2007
    ..To assess the effect of high-dose N-acetylcysteine on renal function in cardiac surgery patients at higher risk of postoperative renal failure...
  35. ncbi request reprint Hemodialysis membrane with a high-molecular-weight cutoff and cytokine levels in sepsis complicated by acute renal failure: a phase 1 randomized trial
    Michael Haase
    Intensive Care Unit, Austin Hospital, University of Melbourne, Australia
    Am J Kidney Dis 50:296-304. 2007
    ..However, standard hemodialysis membranes achieve only little diffusive removal of circulating cytokines. Modified membranes may enable both successful IHD treatment and simultaneous diffusive cytokine removal...
  36. doi request reprint A comparison of the Niagara™ and Dolphin® catheters for continuous renal replacement therapy
    Inbyung Kim
    Department of Intensive Care Medicine, Austin Hospital, Melbourne, Australia
    Int J Artif Organs 34:1061-6. 2011
    ..The choice of vascular access catheter may affect filter life during continuous renal replacement therapy (CRRT); specifically, a new surface-modified catheter has been reported to possibly prevent thrombosis and catheter malfunction...
  37. doi request reprint Septic shock induces distinct changes in sympathetic nerve activity to the heart and kidney in conscious sheep
    Rohit Ramchandra
    Howard Florey Institute, University of Melbourne, Parkville, Victoria, Australia
    Am J Physiol Regul Integr Comp Physiol 297:R1247-53. 2009
    ..There was little correlation between the changes in RSNA and renal blood flow, suggesting that the renal vasodilatation was mediated mainly by other mechanisms...
  38. ncbi request reprint Increasing renal blood flow: low-dose dopamine or medium-dose norepinephrine
    David Di Giantomasso
    Department of Intensive Care, Austin and Repatriation Medical Centre, Heidelberg, Germany
    Chest 125:2260-7. 2004
    ..The aim of this study was to compare the effects of 6 h of IV LDD and MD-NE infusion on mammalian renal, coronary, mesenteric, and sagittal blood flow...
  39. ncbi request reprint Characteristics and outcomes of patients receiving a medical emergency team review for respiratory distress or hypotension
    Jon L Quach
    Department of Intensive Care, Austin Hospital, University of Melbourne, Heidelberg, Victoria 3084, Australia
    J Crit Care 23:325-31. 2008
    ..To describe the characteristics and outcomes of patients receiving a medical emergency team (MET) review for the MET syndromes of respiratory distress or hypotension and to assess the effect of delayed MET activation on their outcomes...
  40. doi request reprint N-Acetylcysteine does not artifactually lower plasma creatinine concentration
    Michael Haase
    Director of Intensive Care Research, Austin Hospital, University of Melbourne, 3084 Heidelberg, Victoria, Australia
    Nephrol Dial Transplant 23:1581-7. 2008
    ..However, it has been suggested that NAC may lower plasma creatinine levels independent of any effects on glomerular filtration rate (GFR)...
  41. ncbi request reprint Does severe non-infectious SIRS differ from severe sepsis? Results from a multi-centre Australian and New Zealand intensive care unit study
    Joel M Dulhunty
    Department of Intensive Care Medicine, Royal Brisbane and Women s Hospital, and Burns, Trauma and Critical Care Research Centre, University of Queensland, Herston, QLD, 4029, Australia
    Intensive Care Med 34:1654-61. 2008
    ..To compare the time course of organ dysfunction/failure, mortality and cause of death in patients with severe sepsis (SS) and patients with severe non-infectious systemic inflammatory response syndrome (SNISIRS)...
  42. ncbi request reprint External validation of severity scoring systems for acute renal failure using a multinational database
    Shigehiko Uchino
    Department of Intensive Care, Austin Hospital, Melbourne, Australia
    Crit Care Med 33:1961-7. 2005
    ..Therefore, it is not known whether such severity scoring systems may be widely applied...
  43. pmc Oliguria as predictive biomarker of acute kidney injury in critically ill patients
    John R Prowle
    Department of Intensive Care, Austin Hospital, 145 Studley Road, Heidleberg, Victoria 3084, Australia
    Crit Care 15:R172. 2011
    ..During critical illness, oliguria is often used as a biomarker of acute kidney injury (AKI). However, its relationship with the subsequent development of AKI has not been prospectively evaluated...
  44. pmc Dynamic lactate indices as predictors of outcome in critically ill patients
    Alistair Nichol
    Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Commercial Road, Melbourne, Vic, Australia
    Crit Care 15:R242. 2011
    ..We aimed to compare the predictive value of dynamic indices of lactatemia in the first 24 hours of intensive care unit (ICU) admission with the value of more commonly used static indices...
  45. ncbi request reprint The epidemiology and outcome of medical emergency team call patients treated with non-invasive ventilation
    Antoine G Schneider
    Intensive Care Unit, Austin Health 145 Studley Road Heidelberg, Melbourne, Victoria 3084, Australia
    Resuscitation 82:1218-23. 2011
    ..However, NIV is sometimes used by the Medical Emergency Team (MET) as respiratory support for ward patients...
  46. pmc Arterial hyperoxia and in-hospital mortality after resuscitation from cardiac arrest
    Rinaldo Bellomo
    Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, 5 Commercial Road, Prahran, Melbourne, Victoria 3181, Australia
    Crit Care 15:R90. 2011
    ..Hyperoxia has recently been reported as an independent risk factor for mortality in patients resuscitated from cardiac arrest. We examined the independent relationship between hyperoxia and outcomes in such patients...
  47. ncbi request reprint Variability of blood glucose concentration and short-term mortality in critically ill patients
    Moritoki Egi
    Department of Intensive Care, Austin Hospital, Heidelberg, Victoria, Australia
    Anesthesiology 105:244-52. 2006
    ..Intensive insulin therapy also reduced the SD of blood glucose concentration, an accepted measure of variability. There is no information on the possible significance of variability in glucose concentration...
  48. ncbi request reprint Renal vascular resistance in sepsis
    Christoph Langenberg
    Departments of Intensive Care and Medicine, Austin Hospital and University of Melbourne, Heidelberg, Melbourne, Australia
    Nephron Physiol 104:p1-11. 2006
    ..To assess changes in renal vascular resistance (RVR) in human and experimental sepsis and to identify determinants of RVR...
  49. doi request reprint A prospective study of factors influencing the outcome of patients after a Medical Emergency Team review
    Paolo Calzavacca
    Department of Intensive Care and Department of Medicine, Austin Hospital, Heidelberg, Melbourne, Vic, Australia
    Intensive Care Med 34:2112-6. 2008
    ..To identify factors that predict outcome in patients receiving a Medical Emergency Team review...
  50. ncbi request reprint Novel biomarkers early predict the severity of acute kidney injury after cardiac surgery in adults
    Michael Haase
    Department of Intensive Care, Austin Health, Melbourne, Australia
    Ann Thorac Surg 88:124-30. 2009
    ....
  51. ncbi request reprint The predictive performance of plasma neutrophil gelatinase-associated lipocalin (NGAL) increases with grade of acute kidney injury
    Anja Haase-Fielitz
    Department of Intensive Care, Austin Health, Melbourne, Australia
    Nephrol Dial Transplant 24:3349-54. 2009
    ..The choice of definition of acute kidney injury (AKI) might, at least in part, account for such variability...
  52. ncbi request reprint The effect of albumin concentration on plasma sodium and chloride measurements in critically ill patients
    David A Story
    Department of Anaesthesia, Austin Health, Heidelberg, Victoria, Australia
    Anesth Analg 104:893-7. 2007
    ..Further, we proposed that differences between indirect and direct chloride assays might be explained by interference from other plasma constituents, particularly bicarbonate, and possibly albumin...
  53. ncbi request reprint Safety evaluation of a trial of lipocalin-directed sodium bicarbonate infusion for renal protection in at-risk critically ill patients
    Antoine G Schneider
    Department of Intensive Care, Austin Health, Melbourne, Vic, Australia
    Crit Care Resusc 15:126-33. 2013
    ..The safety and feasibility of urine alkalinisation in patients at risk of s-AKI has never been tested...
  54. ncbi request reprint Bolus hypertonic or normal saline resuscitation in gram-negative sepsis: systemic and regional haemodynamic effects in sheep
    Li Wan
    Department of Intensive Care, Austin Health, Melbourne, Vic, Australia
    Crit Care Resusc 13:262-70. 2011
    ..Fluid resuscitation with saline in severe sepsis is controversial. Hypertonic (3%) saline (HTS) may be superior to normal (0.9%) saline (NS)...
  55. ncbi request reprint Blood glucose on day of intensive care unit admission as a surrogate of subsequent glucose control in intensive care
    Moritoki Egi
    Department of Intensive Care, Western Hospital, Footscray, Victoria, Australia
    J Crit Care 21:197-202. 2006
    ..The aim of the study was to test whether the mean of the highest and lowest glucose values on day 1 (Glu(1)) is a useful surrogate marker of mean blood glucose during the totality of intensive care unit (ICU) stay (Glu(tot))...
  56. doi request reprint A comparison of observed versus estimated baseline creatinine for determination of RIFLE class in patients with acute kidney injury
    Sean M Bagshaw
    Department of Intensive Care, Austin and Repatriation Medical Centre, Melbourne, Australia
    Nephrol Dial Transplant 24:2739-44. 2009
    ..When unknown, current recommendations are to estimate a baseline SCr by the MDRD equation. However, the MDRD approach assumes a glomerular filtration rate of approximately 75 mL/min/1.73 m(2). This method has not been validated...
  57. ncbi request reprint Pre-dilution vs. post-dilution during continuous veno-venous hemofiltration: impact on filter life and azotemic control
    Shigehiko Uchino
    Department of Intensive Care, Austin and Repatriation Medical Centre, Melbourne, Vic, Australia
    Nephron Clin Pract 94:c94-8. 2003
    ..To determine the impact of replacement fluid infusion site on filter life and azotemic control during continuous veno-venous hemofiltration (CVVH)...
  58. doi request reprint Ciné phase-contrast magnetic resonance imaging for the measurement of renal blood flow
    John R Prowle
    Department of Intensive Care, Austin Health, Melbourne, Australia
    Contrib Nephrol 165:329-36. 2010
    ..We have recently assessed the feasibility of measuring RBF by means of CPC-MRI in 2 critically ill patients with septic acute kidney injury and were able to compare such measurements to those obtained in a normal volunteer...
  59. pmc Effect of the medical emergency team on long-term mortality following major surgery
    Daryl Jones
    Australian and New Zealand Intensive Care Research Centre ANZIC RC, Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, 3004, Australia
    Crit Care 11:R12. 2007
    ..The purpose of the present study was to assess the effect of the MET and other variables on long-term mortality in this patient population...
  60. pmc Introduction of medical emergency teams in Australia and New Zealand: a multi-centre study
    Daryl Jones
    Australian and New Zealand Intensive Care Research Centre, Department of Epidemiology and Preventive Medicine, Monash University, 89 Commercial Road, Melbourne 3004, Victoria, Australia
    Crit Care 12:R46. 2008
    ....
  61. ncbi request reprint Loop diuretics in the management of acute renal failure: a systematic review and meta-analysis
    Sean M Bagshaw
    Department of Intensive Care, Austin Hospital, Melbourne, Vic, Australia
    Crit Care Resusc 9:60-8. 2007
    ..We systematically reviewed the literature comparing loop diuretics with control in the management of ARF...
  62. ncbi request reprint Pilot randomised double-blind controlled trial of high-dose spironolactone in critically ill patients receiving a frusemide infusion
    Yogesh Apte
    Department of Intensive Care, Austin Hospital, Melbourne, Vic
    Crit Care Resusc 10:306-11. 2008
    ..Spironolactone is an aldosterone antagonist that promotes natriuresis and may attenuate such hypernatraemia, but its effect in this setting has not been previously studied...
  63. doi request reprint Hypophosphatemia in critically ill patients
    Satoshi Suzuki
    Department of Intensive Care, Austin Hospital, Melbourne, Victoria, Australia
    J Crit Care 28:536.e9-19. 2013
    ..The aim of this study was to assess the association of phosphate concentration with key clinical outcomes in a heterogeneous cohort of critically ill patients...
  64. doi request reprint Treatment limitations at admission to intensive care units in Australia and New Zealand: prevalence, outcomes, and resource use*
    GEORGE GODFREY
    Department of Intensive CareThe Alfred Hospital, Melbourne, Victoria, Australia
    Crit Care Med 40:2082-9. 2012
    ..However, no studies have investigated the epidemiology of patients with treatment limitations in place at the time of intensive care unit admission...
  65. pmc The effects of terlipressin on regional hemodynamics and kidney function in experimental hyperdynamic sepsis
    Ken Ishikawa
    Howard Florey Institute, University of Melbourne, Parkville, Victoria, Australia
    PLoS ONE 7:e29693. 2012
    ..We investigated the effects of TP on regional hemodynamics and kidney function in experimental hyperdynamic sepsis...
  66. doi request reprint A comparison of epinephrine and norepinephrine in critically ill patients
    John A Myburgh
    Department of Intensive Care Medicine, The St George Hospital, Gray Street, Kogarah, Sydney 2217, Australia
    Intensive Care Med 34:2226-34. 2008
    ..To determine whether there was a difference between epinephrine and norepinephrine in achieving a mean arterial pressure (MAP) goal in intensive care (ICU) patients...
  67. ncbi request reprint Electrolyte mass balance during CVVH: lactate vs. bicarbonate-buffered replacement fluids
    Han Khim Tan
    Department of Intensive Care and Surgery, Austin Hospital, Melbourne, Australia
    Ren Fail 26:149-53. 2004
    ..To compare the effect of lactate vs. bicarbonate-buffered replacement fluids on electrolyte mass balance during isovolemic continuous veno-venous hemofiltration (CVVH)...
  68. ncbi request reprint Acute renal failure in critically ill patients: a multinational, multicenter study
    Shigehiko Uchino
    Department of Intensive Care, Austin Hospital, Melbourne, Australia
    JAMA 294:813-8. 2005
    ....
  69. ncbi request reprint Norepinephrine for hypotensive vasodilatation after cardiac surgery: impact on renal function
    Hiroshi Morimatsu
    Departments of Intensive Care and Medicine, Austin and Repatriation Medical Centre, Melbourne University, Studley Road, Heidelberg, 3084, Melbourne, Victoria, Australia
    Intensive Care Med 29:1106-12. 2003
    ..Accordingly, we studied the renal effects of norepinephrine use for hypotensive vasodilatation after cardiac surgery...
  70. ncbi request reprint End-stage renal failure patients requiring renal replacement therapy in the intensive care unit: incidence, clinical features, and outcome
    Shigehiko Uchino
    Departments of Intensive Care and Medicine, Austin and Repatriation Medical Centre, Melbourne, Australia
    Blood Purif 21:170-5. 2003
    ....
  71. doi request reprint Circuit start during continuous renal replacement therapy in vasopressor-dependent patients: the impact of a slow blood flow protocol
    In Byung Kim
    Department of Intensive Care Medicine, Austin Hospital, Melbourne, Vic, Australia
    Blood Purif 32:1-6. 2011
    ..In vasopressor-dependent patients, we evaluated the impact of a slow blood flow protocol on hypotension when starting continuous renal replacement therapy (CRRT)...
  72. ncbi request reprint The effects of saline or albumin resuscitation on acid-base status and serum electrolytes
    Rinaldo Bellomo
    Department of Intensive Care, Austin Hospital, Melbourne, Australia
    Crit Care Med 34:2891-7. 2006
    ..To test whether fluid resuscitation with normal saline or 4% albumin is associated with differential changes in acid-base status and serum electrolytes...
  73. doi request reprint Insertion side, body position and circuit life during continuous renal replacement therapy with femoral vein access
    In Byung Kim
    Department of Intensive Care Medicine, Austin Hospital, Studley Road, Melbourne, VIC 3084, Australia
    Blood Purif 31:42-6. 2011
    ..We investigated if there is an association between choice of insertion side and body position and its changes and circuit life during CRRT with femoral vein access...
  74. ncbi request reprint Vital organ blood flow during hyperdynamic sepsis
    David Di Giantomasso
    Howard Florey Institute, Parkville, Melbourne, Australia
    Chest 124:1053-9. 2003
    ..To develop a nonlethal model of hyperdynamic sepsis, and to measure vital organ blood flows in this setting...
  75. doi request reprint Features and outcome of patients receiving multiple Medical Emergency Team reviews
    Paolo Calzavacca
    Department of Intensive Care, Austin Hospital, Melbourne, Australia
    Resuscitation 81:1509-15. 2010
    ..Accordingly, we studied the characteristics and outcome of patients receiving one MET call and compared them with those receiving multiple MET reviews...
  76. ncbi request reprint A pilot randomised controlled comparison of continuous veno-venous haemofiltration and extended daily dialysis with filtration: effect on small solutes and acid-base balance
    Ian Baldwin
    Department of Intensive Care, Austin Health, 3084, Heidelberg, Australia
    Intensive Care Med 33:830-5. 2007
    ..Recently, extended intermittent dialytic techniques have been proposed for the treatment of ARF. The aim of this study was to compare these two approaches...
  77. ncbi request reprint Urinary biochemistry and microscopy in septic acute renal failure: a systematic review
    Sean M Bagshaw
    Department of Intensive Care, Austin Hospital, Heidelberg, Victoria 3084, Australia
    Am J Kidney Dis 48:695-705. 2006
    ..Biochemistry and microscopy of urine are widely published diagnostic activities in patients with acute renal failure (ARF). However, their scientific basis in patients with septic ARF has not been assessed systematically...
  78. ncbi request reprint Defining and classifying acute renal failure: from advocacy to consensus and validation of the RIFLE criteria
    Rinaldo Bellomo
    Department of Intensive Care and Department of Medicine, Austin Hospital and University of Melbourne, Heidelberg, Melbourne, Australia
    Intensive Care Med 33:409-13. 2007
    ..This editorial aims to summarize and interpret recent findings concerning the application of the RIFLE criteria to the assessment of the epidemiology and the prediction of the outcome of ARF...
  79. ncbi request reprint Circadian rhythm of blood glucose values in critically ill patients
    Moritoki Egi
    Department of Intensive Care, Austin Hospital, Heidelberg, Victoria, Australia
    Crit Care Med 35:416-21. 2007
    ..To test whether there is a circadian rhythm of blood glucose control in critically ill patients and whether morning blood glucose is an accurate surrogate of overall blood glucose control...
  80. doi request reprint Vasoactive drugs and acute kidney injury
    Rinaldo Bellomo
    Department of Intensive Care and Medicine, Austin Hospital, Melbourne, Australia
    Crit Care Med 36:S179-86. 2008
    ..Whether it is superior to noradrenaline in this setting remains uncertain, and more studies are needed before recommendations can be made...
  81. doi request reprint A comparison of the RIFLE and AKIN criteria for acute kidney injury in critically ill patients
    Sean M Bagshaw
    Department of Intensive Care, Austin Hospital, Heidelberg, Victoria 3084, Australia
    Nephrol Dial Transplant 23:1569-74. 2008
    ..The Acute Kidney Injury Network (AKIN) group has recently proposed modifications to this system. It is currently unknown whether there are advantages between these criteria...
  82. pmc Bench-to-bedside review: The MET syndrome--the challenges of researching and adopting medical emergency teams
    Augustine Tee
    Department of Intensive Care, Austin Hospital, Studley Road, Heidelberg, Melbourne, Victoria 3084, Australia
    Crit Care 12:205. 2008
    ..It appears likely that the accumulation of evidence from different settings and situations, though methodologically imperfect, will increase the rationale and logic of RRS. A conclusive randomised controlled trial is unlikely to occur...
  83. pmc The pursuit of a high central venous oxygen saturation in sepsis: growing concerns
    Rinaldo Bellomo
    Department of Intensive Care, Austin Hospital, Studley Rd, Heidelberg, Victoria 3084, Australia
    Crit Care 12:130. 2008
    ..Until such studies are completed, basing international treatment guidelines on a single centre study performed in what may turn out to be a highly atypical environment would seem premature...
  84. pmc Acute renal failure - definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group
    Rinaldo Bellomo
    Department of Intensive Care and Medicine, Austin Health, Melbourne, Australia
    Crit Care 8:R204-12. 2004
    ..Accordingly, we sought to review the available evidence, make recommendations and delineate key questions for future studies...
  85. ncbi request reprint Do we know the optimal dose for renal replacement therapy in the intensive care unit?
    R Bellomo
    Department of Intensive Care, Austin and Repatriation Medical Centre, Heidelberg, Victoria, Australia
    Kidney Int 70:1202-4. 2006
    ..The results of these two studies should be available in 2008. Before making any major changes to practice, it seems prudent to wait for the publication of the findings of these two pivotal trials...
  86. ncbi request reprint Strong ions, weak acids and base excess: a simplified Fencl-Stewart approach to clinical acid-base disorders
    D A Story
    Department of Anaesthesia, and Department of Intensive Care, Austin and Repatriation Medical Centre, Heidelberg, Victoria 3084, Australia
    Br J Anaesth 92:54-60. 2004
    ..We proposed four simpler equations that require only mental arithmetic and tested the hypothesis that these simpler equations would have good agreement with more complex Fencl-Stewart equations...
  87. ncbi request reprint Estimating unmeasured anions in critically ill patients: anion-gap, base-deficit, and strong-ion-gap
    D A Story
    Department of Intensive are, Austin and Repatriation Medical Centre, Heidelberg, Victoria, Australia
    Anaesthesia 57:1109-14. 2002
    ..001), and the proportion with a base-deficit > 5 meq.l(-1) increased from 8 to 42% (p < 0.001). Consequently, metabolic acidosis from unmeasured ions in critically ill patients maybe more frequent than often recognised...
  88. ncbi request reprint Epidemiology, management, and outcome of severe acute renal failure of critical illness in Australia
    W Silvester
    Department of Intensive Care, Austin and Repatriation Medical Centre, Melbourne, Victoria, Australia
    Crit Care Med 29:1910-5. 2001
    ..Renal replacement therapy is continuous and outcomes are satisfactory. Our findings support the view that this approach to management of severe acute renal failure is safe...
  89. ncbi request reprint Continuous renal replacement therapy: does technique influence electrolyte and bicarbonate control?
    H Morimatsu
    Department of Intensive Care and Department of Medicine, Austin and Repatriation Medical Centre, Melbourne, Victoria, Australia
    Int J Artif Organs 26:289-96. 2003
    ..The aim of this study was to determine whether continuous veno-venous hemodiafiltration (CVVHDF) or continuous veno-venous hemofiltration (CVVH) achieve better control of serum sodium, potassium and bicarbonate concentrations...
  90. ncbi request reprint Impact of continuous veno-venous hemofiltration on acid-base balance
    J Rocktaschel
    Department of Intensive Care, University of Melbourne, Austin and Repatriation Medical Centre, Melbourne, Australia
    Int J Artif Organs 26:19-25. 2003
    ....
  91. ncbi request reprint Prolonged daily intermittent renal replacement therapy in ICU patients by ICU nurses and ICU physicians
    T Naka
    Department of Intensive Care, Austin Hospital and Melbourne University, Melbourne, Australia
    Int J Artif Organs 27:380-7. 2004
    ....
  92. ncbi request reprint Quantitative physical chemistry analysis of acid-base disorders in critically ill patients
    D A Story
    Department of Anaesthesia, and Director of Research, Department of Intensive Care, Austin and Repatriation Medical Centre, Studley Road, Heidelberg, Victoria 3084, Australia
    Anaesthesia 56:530-3. 2001
    ..8 mmol.l-1. From Stewart's approach, the most likely explanation for the overall alkalosis was decreased total weak-acid concentration resulting from decreased plasma albumin concentration...
  93. ncbi request reprint Intermittent versus continuous renal replacement therapy in the ICU: impact on electrolyte and acid-base balance
    S Uchino
    Department of Intensive Care, Austin and Repatriation Medical Centre, Heidelberg, Melbourne, Victoria, Australia
    Intensive Care Med 27:1037-43. 2001
    ..Normalization of these values, however, is achieved more frequently with CVVHDF than with IHD...
  94. ncbi request reprint Kidney failure associated with liver transplantation or liver failure: the impact of continuous veno-venous hemofiltration
    T Naka
    Department of Intensive Care and Surgery, Austin Hospital, Melbourne, Australia
    Int J Artif Organs 27:949-55. 2004
    ..We sought to test the hypothesis that, with the exclusive use of continuous veno-venous hemofilration (CVVH) with minimal heparin-anticoagulation, the short and long-term outcomes of these patients would be improved...
  95. ncbi request reprint Comparison of three methods to estimate plasma bicarbonate in critically ill patients: Henderson-Hasselbalch, enzymatic, and strong-ion-gap
    D A Story
    Department of Anaesthesia, Austin and Repatriation Medical Centre, University of Melbourne, Victoria
    Anaesth Intensive Care 29:585-90. 2001
    ..The strong-ion-gap method is currently too inaccurate for clinical application, but may have future use...
  96. ncbi request reprint Acid-base balance during continuous veno-venous hemofiltration: the impact of severe hepatic failure
    T Naka
    Department of Intensive Care, Austin Hospital and Melbourne University, Melbourne, Australia
    Int J Artif Organs 29:668-74. 2006
    ..Continuous renal replacement therapy (CRRT) affects acid-base balance but the influence of severe hepatic failure (SHF) on this effect is unknown...
  97. ncbi request reprint Acid-base balance in combined severe hepatic and renal failure: a quantitative analysis
    T Naka
    Department of Intensive Care, Austin Hospital, Melbourne, Australia
    Int J Artif Organs 31:288-94. 2008
    ..However, the direct effects of liver failure per se on acid base balance are poorly understood because this condition is usually associated with acute renal failure (ARF)...
  98. ncbi request reprint The Acute Dialysis Quality Initiative II: the Vicenza conference
    Rinaldo Bellomo
    Department of Intensive Care, Austin and Repatriation Hospital, Melbourne, Australia
    Adv Ren Replace Ther 9:290-3. 2002
    ..These developments have set the stage for the first conference and have now driven the spirit of the second. Once again, the final objectives are the development of evidence-based guidelines and directions for future research...
  99. ncbi request reprint Acute Dialysis Quality Initiative II: the Vicenza conference
    Rinaldo Bellomo
    Intensive Care Unit, Austin and Repatriation Medical Centre, Heidelberg, Victoria, Australia
    Curr Opin Crit Care 8:505-8. 2002
    ..Accordingly, the second Acute Dialysis Quality Initiative conference in Vicenza, Italy, was organized, and its goals and rationale are presented in this report...
  100. ncbi request reprint Platelet loss across the hemofilter during continuous hemofiltration
    J Mulder
    Department of Intensive Care, Austin Hospital, Melbourne, Australia
    Int J Artif Organs 26:906-12. 2003
    ..Thrombocytopenia is a common finding in patients in the intensive care unit receiving continuous renal replacement therapy (CRRT). It is unknown if the hemofilter itself contributes to the platelet loss...
  101. ncbi request reprint Continuous veno-venous hemodiafiltration or hemofiltration: impact on calcium, phosphate and magnesium concentrations
    H Morimatsu
    Department of Intensive Care, Austin and Repatriation Medical Centre, Melbourne, Victoria, Australia
    Int J Artif Organs 25:512-9. 2002
    ..Accordingly, we tested whether continuous veno-venous hemodia filtration (CVVHDF) or continuous venovenous hemofiltration (CVVH) would achieve better control of these electrolytes...