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Genomes and GenesSpecies | Sammy BedouiSummaryAffiliation: University of Melbourne Country: Australia Publications
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Publications
Different bacterial pathogens, different strategies, yet the aim is the same: evasion of intestinal dendritic cell recognitionSammy Bedoui
Department of Microbiology and Immunology, University of Melbourne, Gate 11, Royal Parade, Parkville 3010, Victoria, Australia E mail address
J Immunol 184:2237-42. 2010..These diverse strategies span to include mounting irrelevant immune responses, inhibition of Ag presentation by DCs, and stretch as far as to manipulate the Th1/Th2 balance of CD4(+) T cells in the bacteria's favor...- Interaction between dendritic cells and T cells during peripheral virus infections: a role for antigen presentation beyond lymphoid organs?Sammy Bedoui
Department of Microbiology and Immunology, The University of Melbourne, Parkville, Victoria 3010, Australia
Curr Opin Immunol 23:124-30. 2011..Here we discuss the multifaceted interactions between DC and T cells during peripheral virus infections in both lymphoid organs and the periphery... - Equivalent stimulation of naive and memory CD8 T cells by DNA vaccination: a dendritic cell-dependent processSammy Bedoui
Department of Microbiology and Immunology, The University of Melbourne, Victoria, Melbourne, Australia
Immunol Cell Biol 87:255-9. 2009.... - Characterization of an immediate splenic precursor of CD8+ dendritic cells capable of inducing antiviral T cell responsesSammy Bedoui
The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia
J Immunol 182:4200-7. 2009..The enhanced capacity of CD8(-)CD24(+) DC to induce immune responses upon adoptive transfer makes them an attractive novel tool for DC-based immunotherapies... - Depletion of Gr-1+, but not Ly6G+, immune cells exacerbates virus replication and disease in an intranasal model of herpes simplex virus type 1 infectionMagdalena Wojtasiak
Department of Microbiology and Immunology, University of Melbourne, Parkville, VIC 3010, Australia
J Gen Virol 91:2158-66. 2010..Furthermore, we use mAb 1A8 to demonstrate that specific depletion of neutrophils does not modulate disease or alter virus replication following intranasal infection with HSV-1... - Cross-presentation of viral and self antigens by skin-derived CD103+ dendritic cellsSammy Bedoui
The Department of Microbiology and Immunology, The University of Melbourne, Parkville, Victoria, Australia
Nat Immunol 10:488-95. 2009..This indicates CD103(+) DCs are the main migratory subtype able to cross-present viral and self antigens, which identifies another level of specialization for skin DCs... - Cutting edge: priming of CD8 T cell immunity to herpes simplex virus type 1 requires cognate TLR3 expression in vivoGayle M Davey
Department of Microbiology and Immunology, The University of Melbourne, Parkville, 3010, Victoria, Australia
J Immunol 184:2243-6. 2010..These data imply that a cognate linkage between TLR3 and MHC class I is required for efficient CTL priming to HSV-1... 
Transience of MHC Class I-restricted antigen presentation after influenza A virus infectionJustine D Mintern
Department of Microbiology and Immunology, University of Melbourne, Parkville 3010, Australia
Proc Natl Acad Sci U S A 106:6724-9. 2009..Molecular profiles identified in antigen-specific T cells at this time may thus be considered to reflect established immunologic memory and not recent CTL activation from a persistent pMHCI pool...- Reactive murine lymph nodes uniquely permit parenchymal access for T cells that enter via the afferent lymphaticsLiv Eidsmo
Department of Microbiology and Immunology, The University of Melbourne, Melbourne, Victoria 3010, Australia
J Pathol 226:806-13. 2012..Thus, activated T cells that enter a given lymph node using the afferent lymphatics do not have automatic access to the parenchyma unless it is a reactive node involved with peripheral inflammation or infection... - Contribution of Thy1+ NK cells to protective IFN-γ production during Salmonella typhimurium infectionsAndreas Kupz
Department of Microbiology and Immunology, University of Melbourne, Parkville, 3010 Vic, Australia
Proc Natl Acad Sci U S A 110:2252-7. 2013..Taken together, these findings demonstrate that Thy1-expressing NK cells play an important role in antibacterial immunity... - NLRC4 inflammasomes in dendritic cells regulate noncognate effector function by memory CD8⁺ T cellsAndreas Kupz
Department of Microbiology and Immunology, The University of Melbourne, Parkville, Victoria, Australia
Nat Immunol 13:162-9. 2012..These findings provide a comprehensive mechanistic framework for the regulation of noncognate memory T cell responses during bacterial immunity... - GM-CSF increases cross-presentation and CD103 expression by mouse CD8⁺ spleen dendritic cellsYifan Zhan
Immunology Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia
Eur J Immunol 41:2585-95. 2011..Our findings not only identify GM-CSF as a key molecule regulating CD8(+) DC function, but also as a factor responsible for functional heterogeneity of CD8(+) DCs that is at least substantially demarcated by CD103 expression... - Gr-1+ cells, but not neutrophils, limit virus replication and lesion development following flank infection of mice with herpes simplex virus type-1Magdalena Wojtasiak
Department of Microbiology and Immunology, University of Melbourne, Victoria, 3010, Australia
Virology 407:143-51. 2010..In contrast, Gr-1(+) cells limit both virus replication and lesion development in the zosteriform model... 
Minimal activation of memory CD8+ T cell by tissue-derived dendritic cells favors the stimulation of naive CD8+ T cellsGabrielle T Belz
Immunology Division, The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria 3050, Australia
Nat Immunol 8:1060-6. 2007....- Migratory dendritic cells transfer antigen to a lymph node-resident dendritic cell population for efficient CTL primingRhys S Allan
The Department of Microbiology and Immunology, The University of Melbourne, Parkville 3010, Victoria, Australia
Immunity 25:153-62. 2006.... - Indiscriminate memories during infection controlSammy Bedoui
Department of Microbiology and Immunology, The University of Melbourne, Melbourne, Victoria 3010, Australia
Immunity 37:445-6. 2012..In this issue of Immunity, Soudja et al. (2012) demonstrate that non-antigen-specific stimulation evoked by a variety of pathogens plays an important role in the innate acquisition of effector function by memory CD8(+) T cells... - Putative IKDCs are functionally and developmentally similar to natural killer cells, but not to dendritic cellsIrina Caminschi
Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, 3050, Australia
J Exp Med 204:2579-90. 2007..Thus, IKDCs resemble NK cells functionally, and neither cell type could be induced to be effective antigen-presenting cells... - A Local Role for CD103(+) Dendritic Cells in AtherosclerosisSammy Bedoui
Department of Microbiology and Immunology, The University of Melbourne, Parkville 3010, Victoria, Australia
Immunity 35:665-7. 2011..2011) analyzed the cellular composition of aortic vessels in normal and atherosclerotic mice, revealing the presence of conventional CD103(+) DCs with a potentially protective influence on atherosclerosis... - A role for neuropeptide Y (NPY) in phagocytosis: implications for innate and adaptive immunitySammy Bedoui
Immunology Division, The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria 3051, Australia
Peptides 28:373-6. 2007..Furthermore, we will discuss the implications of these findings for antigen presentation by dendritic cells and the induction of adaptive immune responses...