Sammy Bedoui

Summary

Affiliation: University of Melbourne
Country: Australia

Publications

  1. doi request reprint Interaction between dendritic cells and T cells during peripheral virus infections: a role for antigen presentation beyond lymphoid organs?
    Sammy Bedoui
    Department of Microbiology and Immunology, The University of Melbourne, Parkville, Victoria 3010, Australia
    Curr Opin Immunol 23:124-30. 2011
  2. doi request reprint Different bacterial pathogens, different strategies, yet the aim is the same: evasion of intestinal dendritic cell recognition
    Sammy Bedoui
    Department of Microbiology and Immunology, University of Melbourne, Gate 11, Royal Parade, Parkville 3010, Victoria, Australia E mail address
    J Immunol 184:2237-42. 2010
  3. doi request reprint Equivalent stimulation of naive and memory CD8 T cells by DNA vaccination: a dendritic cell-dependent process
    Sammy Bedoui
    Department of Microbiology and Immunology, The University of Melbourne, Victoria, Melbourne, Australia
    Immunol Cell Biol 87:255-9. 2009
  4. doi request reprint Characterization of an immediate splenic precursor of CD8+ dendritic cells capable of inducing antiviral T cell responses
    Sammy Bedoui
    The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia
    J Immunol 182:4200-7. 2009
  5. doi request reprint Depletion of Gr-1+, but not Ly6G+, immune cells exacerbates virus replication and disease in an intranasal model of herpes simplex virus type 1 infection
    Magdalena Wojtasiak
    Department of Microbiology and Immunology, University of Melbourne, Parkville, VIC 3010, Australia
    J Gen Virol 91:2158-66. 2010
  6. doi request reprint Cross-presentation of viral and self antigens by skin-derived CD103+ dendritic cells
    Sammy Bedoui
    The Department of Microbiology and Immunology, The University of Melbourne, Parkville, Victoria, Australia
    Nat Immunol 10:488-95. 2009
  7. doi request reprint Cutting edge: priming of CD8 T cell immunity to herpes simplex virus type 1 requires cognate TLR3 expression in vivo
    Gayle M Davey
    Department of Microbiology and Immunology, The University of Melbourne, Parkville, 3010, Victoria, Australia
    J Immunol 184:2243-6. 2010
  8. pmc Transience of MHC Class I-restricted antigen presentation after influenza A virus infection
    Justine D Mintern
    Department of Microbiology and Immunology, University of Melbourne, Parkville 3010, Australia
    Proc Natl Acad Sci U S A 106:6724-9. 2009
  9. pmc Contribution of Thy1+ NK cells to protective IFN-γ production during Salmonella typhimurium infections
    Andreas Kupz
    Department of Microbiology and Immunology, University of Melbourne, Parkville, 3010 Vic, Australia
    Proc Natl Acad Sci U S A 110:2252-7. 2013
  10. doi request reprint Reactive murine lymph nodes uniquely permit parenchymal access for T cells that enter via the afferent lymphatics
    Liv Eidsmo
    Department of Microbiology and Immunology, The University of Melbourne, Melbourne, Victoria 3010, Australia
    J Pathol 226:806-13. 2012

Collaborators

Detail Information

Publications20

  1. doi request reprint Interaction between dendritic cells and T cells during peripheral virus infections: a role for antigen presentation beyond lymphoid organs?
    Sammy Bedoui
    Department of Microbiology and Immunology, The University of Melbourne, Parkville, Victoria 3010, Australia
    Curr Opin Immunol 23:124-30. 2011
    ..Here we discuss the multifaceted interactions between DC and T cells during peripheral virus infections in both lymphoid organs and the periphery...
  2. doi request reprint Different bacterial pathogens, different strategies, yet the aim is the same: evasion of intestinal dendritic cell recognition
    Sammy Bedoui
    Department of Microbiology and Immunology, University of Melbourne, Gate 11, Royal Parade, Parkville 3010, Victoria, Australia E mail address
    J Immunol 184:2237-42. 2010
    ..These diverse strategies span to include mounting irrelevant immune responses, inhibition of Ag presentation by DCs, and stretch as far as to manipulate the Th1/Th2 balance of CD4(+) T cells in the bacteria's favor...
  3. doi request reprint Equivalent stimulation of naive and memory CD8 T cells by DNA vaccination: a dendritic cell-dependent process
    Sammy Bedoui
    Department of Microbiology and Immunology, The University of Melbourne, Victoria, Melbourne, Australia
    Immunol Cell Biol 87:255-9. 2009
    ....
  4. doi request reprint Characterization of an immediate splenic precursor of CD8+ dendritic cells capable of inducing antiviral T cell responses
    Sammy Bedoui
    The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia
    J Immunol 182:4200-7. 2009
    ..The enhanced capacity of CD8(-)CD24(+) DC to induce immune responses upon adoptive transfer makes them an attractive novel tool for DC-based immunotherapies...
  5. doi request reprint Depletion of Gr-1+, but not Ly6G+, immune cells exacerbates virus replication and disease in an intranasal model of herpes simplex virus type 1 infection
    Magdalena Wojtasiak
    Department of Microbiology and Immunology, University of Melbourne, Parkville, VIC 3010, Australia
    J Gen Virol 91:2158-66. 2010
    ..Furthermore, we use mAb 1A8 to demonstrate that specific depletion of neutrophils does not modulate disease or alter virus replication following intranasal infection with HSV-1...
  6. doi request reprint Cross-presentation of viral and self antigens by skin-derived CD103+ dendritic cells
    Sammy Bedoui
    The Department of Microbiology and Immunology, The University of Melbourne, Parkville, Victoria, Australia
    Nat Immunol 10:488-95. 2009
    ..This indicates CD103(+) DCs are the main migratory subtype able to cross-present viral and self antigens, which identifies another level of specialization for skin DCs...
  7. doi request reprint Cutting edge: priming of CD8 T cell immunity to herpes simplex virus type 1 requires cognate TLR3 expression in vivo
    Gayle M Davey
    Department of Microbiology and Immunology, The University of Melbourne, Parkville, 3010, Victoria, Australia
    J Immunol 184:2243-6. 2010
    ..These data imply that a cognate linkage between TLR3 and MHC class I is required for efficient CTL priming to HSV-1...
  8. pmc Transience of MHC Class I-restricted antigen presentation after influenza A virus infection
    Justine D Mintern
    Department of Microbiology and Immunology, University of Melbourne, Parkville 3010, Australia
    Proc Natl Acad Sci U S A 106:6724-9. 2009
    ..Molecular profiles identified in antigen-specific T cells at this time may thus be considered to reflect established immunologic memory and not recent CTL activation from a persistent pMHCI pool...
  9. pmc Contribution of Thy1+ NK cells to protective IFN-γ production during Salmonella typhimurium infections
    Andreas Kupz
    Department of Microbiology and Immunology, University of Melbourne, Parkville, 3010 Vic, Australia
    Proc Natl Acad Sci U S A 110:2252-7. 2013
    ..Taken together, these findings demonstrate that Thy1-expressing NK cells play an important role in antibacterial immunity...
  10. doi request reprint Reactive murine lymph nodes uniquely permit parenchymal access for T cells that enter via the afferent lymphatics
    Liv Eidsmo
    Department of Microbiology and Immunology, The University of Melbourne, Melbourne, Victoria 3010, Australia
    J Pathol 226:806-13. 2012
    ..Thus, activated T cells that enter a given lymph node using the afferent lymphatics do not have automatic access to the parenchyma unless it is a reactive node involved with peripheral inflammation or infection...
  11. doi request reprint NLRC4 inflammasomes in dendritic cells regulate noncognate effector function by memory CD8⁺ T cells
    Andreas Kupz
    Department of Microbiology and Immunology, The University of Melbourne, Parkville, Victoria, Australia
    Nat Immunol 13:162-9. 2012
    ..These findings provide a comprehensive mechanistic framework for the regulation of noncognate memory T cell responses during bacterial immunity...
  12. doi request reprint GM-CSF increases cross-presentation and CD103 expression by mouse CD8⁺ spleen dendritic cells
    Yifan Zhan
    Immunology Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia
    Eur J Immunol 41:2585-95. 2011
    ..Our findings not only identify GM-CSF as a key molecule regulating CD8(+) DC function, but also as a factor responsible for functional heterogeneity of CD8(+) DCs that is at least substantially demarcated by CD103 expression...
  13. doi request reprint Gr-1+ cells, but not neutrophils, limit virus replication and lesion development following flank infection of mice with herpes simplex virus type-1
    Magdalena Wojtasiak
    Department of Microbiology and Immunology, University of Melbourne, Victoria, 3010, Australia
    Virology 407:143-51. 2010
    ..In contrast, Gr-1(+) cells limit both virus replication and lesion development in the zosteriform model...
  14. ncbi request reprint Minimal activation of memory CD8+ T cell by tissue-derived dendritic cells favors the stimulation of naive CD8+ T cells
    Gabrielle T Belz
    Immunology Division, The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria 3050, Australia
    Nat Immunol 8:1060-6. 2007
    ....
  15. ncbi request reprint Migratory dendritic cells transfer antigen to a lymph node-resident dendritic cell population for efficient CTL priming
    Rhys S Allan
    The Department of Microbiology and Immunology, The University of Melbourne, Parkville 3010, Victoria, Australia
    Immunity 25:153-62. 2006
    ....
  16. doi request reprint Vitamin A notches up CD11b hi DC development
    Angus T Stock
    Department of Microbiology and Immunology, The University of Melbourne, Melbourne, Victoria, Australia
    Eur J Immunol 43:1441-4. 2013
    ....
  17. doi request reprint Indiscriminate memories during infection control
    Sammy Bedoui
    Department of Microbiology and Immunology, The University of Melbourne, Melbourne, Victoria 3010, Australia
    Immunity 37:445-6. 2012
    ..In this issue of Immunity, Soudja et al. (2012) demonstrate that non-antigen-specific stimulation evoked by a variety of pathogens plays an important role in the innate acquisition of effector function by memory CD8(+) T cells...
  18. ncbi request reprint A Local Role for CD103(+) Dendritic Cells in Atherosclerosis
    Sammy Bedoui
    Department of Microbiology and Immunology, The University of Melbourne, Parkville 3010, Victoria, Australia
    Immunity 35:665-7. 2011
    ..2011) analyzed the cellular composition of aortic vessels in normal and atherosclerotic mice, revealing the presence of conventional CD103(+) DCs with a potentially protective influence on atherosclerosis...
  19. pmc Putative IKDCs are functionally and developmentally similar to natural killer cells, but not to dendritic cells
    Irina Caminschi
    Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, 3050, Australia
    J Exp Med 204:2579-90. 2007
    ..Thus, IKDCs resemble NK cells functionally, and neither cell type could be induced to be effective antigen-presenting cells...
  20. ncbi request reprint A role for neuropeptide Y (NPY) in phagocytosis: implications for innate and adaptive immunity
    Sammy Bedoui
    Immunology Division, The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria 3051, Australia
    Peptides 28:373-6. 2007
    ..Furthermore, we will discuss the implications of these findings for antigen presentation by dendritic cells and the induction of adaptive immune responses...