Sandra D Anderson

Summary

Affiliation: University of Sydney
Country: Australia

Publications

  1. ncbi request reprint Budesonide reduces sensitivity and reactivity to inhaled mannitol in asthmatic subjects
    John D Brannan
    Department of Respiratory Medicine, Royal Prince Alfred Hospital, Camperdown, NSW, Australia
    Respirology 7:37-44. 2002
  2. ncbi request reprint Methods for "indirect" challenge tests including exercise, eucapnic voluntary hyperpnea, and hypertonic aerosols
    Sandra D Anderson
    Department of Respiratory Medicine, Royal Prince Alfred Hospital, Camperdown, NSW Australia
    Clin Rev Allergy Immunol 24:27-54. 2003
  3. doi request reprint Bronchial provocation testing: the future
    Sandra D Anderson
    Department of Respiratory and Sleep Medicine, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia
    Curr Opin Allergy Clin Immunol 11:46-52. 2011
  4. ncbi request reprint Laboratory protocol for exercise asthma to evaluate salbutamol given by two devices
    S D Anderson
    Department of Respiratory Medicine, Page Chest Pavilion, Royal Prince Alfred Hospital, Missenden Road, Camperdown NSW 2050 Australia
    Med Sci Sports Exerc 33:893-900. 2001
  5. ncbi request reprint Exercise-induced bronchoconstriction: pathogenesis
    Sandra D Anderson
    Department of Respiratory Medicine, 11 West, Royal Prince Alfred Hospital, Missenden Road, Camperdown NSW 2050, Australia
    Curr Allergy Asthma Rep 5:116-22. 2005
  6. ncbi request reprint Single-dose agents in the prevention of exercise-induced asthma: a descriptive review
    Sandra D Anderson
    Department of Respiratory Medicine, 11 West, Royal Prince Alfred Hospital, Missenden Road, Camperdown, New South Wales 2050, Australia
    Treat Respir Med 3:365-79. 2004
  7. ncbi request reprint Use of aerosols for bronchial provocation testing in the laboratory: where we have been and where we are going
    S D Anderson
    Department of Respiratory Medicine, Royal Prince Alfred Hospital, Camperdown, Australia
    J Aerosol Med 15:313-24. 2002
  8. ncbi request reprint Exercise-induced asthma in children: a marker of airway inflammation
    Sandra D Anderson
    Department of Respiratory Medicine, Royal Prince Alfred Hospital, Missenden Road, Camperdown, NSW
    Med J Aust 177:S61-3. 2002
  9. pmc Provocation by eucapnic voluntary hyperpnoea to identify exercise induced bronchoconstriction
    S D Anderson
    Department of Respiratory Medicine, Level 9 Page Chest Pavilion, Royal Prince Alfred Hospital, Camperdown, NSW 2050, Australia
    Br J Sports Med 35:344-7. 2001
  10. doi request reprint Effect of sodium cromoglycate on mast cell mediators during hyperpnea in athletes
    Pascale Kippelen
    Department of Respiratory and Sleep Medicine, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia
    Med Sci Sports Exerc 42:1853-60. 2010

Detail Information

Publications49

  1. ncbi request reprint Budesonide reduces sensitivity and reactivity to inhaled mannitol in asthmatic subjects
    John D Brannan
    Department of Respiratory Medicine, Royal Prince Alfred Hospital, Camperdown, NSW, Australia
    Respirology 7:37-44. 2002
    ..The aim of the study was to investigate whether treatment using inhaled corticosteroids decreases airway responsiveness to inhaled mannitol in asthmatic subjects...
  2. ncbi request reprint Methods for "indirect" challenge tests including exercise, eucapnic voluntary hyperpnea, and hypertonic aerosols
    Sandra D Anderson
    Department of Respiratory Medicine, Royal Prince Alfred Hospital, Camperdown, NSW Australia
    Clin Rev Allergy Immunol 24:27-54. 2003
    ..Another advantage is that healthy subjects do not have significant airway narrowing to indirect challenge tests. The protocols used for challenge with indirectly acting stimuli are presented in detail...
  3. doi request reprint Bronchial provocation testing: the future
    Sandra D Anderson
    Department of Respiratory and Sleep Medicine, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia
    Curr Opin Allergy Clin Immunol 11:46-52. 2011
    ..This review discusses some long-held beliefs of BPTs to include or exclude a diagnosis of asthma or exercise-induced bronchoconstriction (EIB)...
  4. ncbi request reprint Laboratory protocol for exercise asthma to evaluate salbutamol given by two devices
    S D Anderson
    Department of Respiratory Medicine, Page Chest Pavilion, Royal Prince Alfred Hospital, Missenden Road, Camperdown NSW 2050 Australia
    Med Sci Sports Exerc 33:893-900. 2001
    ..One way to do this is to investigate their equivalence in protecting from exercise-induced asthma (EIA)...
  5. ncbi request reprint Exercise-induced bronchoconstriction: pathogenesis
    Sandra D Anderson
    Department of Respiratory Medicine, 11 West, Royal Prince Alfred Hospital, Missenden Road, Camperdown NSW 2050, Australia
    Curr Allergy Asthma Rep 5:116-22. 2005
    ..The effect of drugs that have the potential to reduce microvascular leak and reduce or inhibit release or action of these mediators needs to be investigated in elite athletes...
  6. ncbi request reprint Single-dose agents in the prevention of exercise-induced asthma: a descriptive review
    Sandra D Anderson
    Department of Respiratory Medicine, 11 West, Royal Prince Alfred Hospital, Missenden Road, Camperdown, New South Wales 2050, Australia
    Treat Respir Med 3:365-79. 2004
    ..It is time to take into account the advantages and disadvantages of the different drugs available to prevent EIA and to recognize that there are some myths related to their use in EIA...
  7. ncbi request reprint Use of aerosols for bronchial provocation testing in the laboratory: where we have been and where we are going
    S D Anderson
    Department of Respiratory Medicine, Royal Prince Alfred Hospital, Camperdown, Australia
    J Aerosol Med 15:313-24. 2002
    ..These findings suggest that indirect challenges give more useful clinical information about currently active asthma and the response to treatment than direct challenge and they will become more widely used...
  8. ncbi request reprint Exercise-induced asthma in children: a marker of airway inflammation
    Sandra D Anderson
    Department of Respiratory Medicine, Royal Prince Alfred Hospital, Missenden Road, Camperdown, NSW
    Med J Aust 177:S61-3. 2002
    ..in preventing EIA throughout the day? How many children taking long-acting beta(2)-agonists twice daily, either alone or in combination with an inhaled steroid, experience breakthrough EIA during school and require rescue medication?..
  9. pmc Provocation by eucapnic voluntary hyperpnoea to identify exercise induced bronchoconstriction
    S D Anderson
    Department of Respiratory Medicine, Level 9 Page Chest Pavilion, Royal Prince Alfred Hospital, Camperdown, NSW 2050, Australia
    Br J Sports Med 35:344-7. 2001
    ..The test conditions can be modified to simulate the conditions that give the athlete their symptoms with exercise. A reduction in FEV(1) of 10% or more of the value before the test is considered positive...
  10. doi request reprint Effect of sodium cromoglycate on mast cell mediators during hyperpnea in athletes
    Pascale Kippelen
    Department of Respiratory and Sleep Medicine, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia
    Med Sci Sports Exerc 42:1853-60. 2010
    ..The role of mast cells in the airway response to exercise and the benefit of sodium cromoglycate (SCG) in athletes are unclear...
  11. doi request reprint Inhaled mannitol improves the hydration and surface properties of sputum in patients with cystic fibrosis
    Evangelia Daviskas
    Department of Respiratory and Sleep Medicine, Royal Prince Alfred Hospital, 11 West, Missenden Rd, Camperdown, Sydney, NSW 2050, Australia
    Chest 137:861-8. 2010
    ..Chest. 2008;133(6):1388-1396). The changes in the physical properties of sputum after a 2-week treatment with mannitol were investigated in the same subjects with CF...
  12. ncbi request reprint Sodium cromoglycate alone and in combination with montelukast on the airway response to mannitol in asthmatic subjects
    Sandra D Anderson
    Department of Respiratory and Sleep Medicine, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia
    J Asthma 47:429-33. 2010
    ....
  13. doi request reprint Airway injury as a mechanism for exercise-induced bronchoconstriction in elite athletes
    Sandra D Anderson
    Department of Respiratory and Sleep Medicine, Royal Prince Alfred Hospital, Camperdown, New South Wales 2050, Australia
    J Allergy Clin Immunol 122:225-35; quiz 236-7. 2008
    ..In those who are allergic, AHR can also be expressed as EIB. The role of beta(2)-receptor agonists in inhibiting and enhancing the development of AHR and EIB is discussed...
  14. doi request reprint Assessment and prevention of exercise-induced bronchoconstriction
    Sandra D Anderson
    Respiratory and Sleep Medicine, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia
    Br J Sports Med 46:391-6. 2012
    ..Other strategies include warming up prior to exercise and reducing respiratory water and heat loss by using face masks or nasal breathing...
  15. pmc Comparison of mannitol and methacholine to predict exercise-induced bronchoconstriction and a clinical diagnosis of asthma
    Sandra D Anderson
    Department of Respiratory and Sleep Medicine, Royal Prince Alfred Hospital, Missenden Road, Camperdown, NSW 2050, Australia
    Respir Res 10:4. 2009
    ....
  16. ncbi request reprint Bronchial challenges in athletes applying to inhale a beta2-agonist at the 2004 Summer Olympics
    Sandra D Anderson
    Department of Respiratory Medicine, Royal Prince Alfred Hospital, Camperdown, NSW, Australia
    J Allergy Clin Immunol 117:767-73. 2006
    ..The International Olympic Committee Medical Commission required a medical justification for athletes to inhale a beta2-agonist before an event at the Summer Games in Athens in 2004...
  17. doi request reprint Beneficial effect of inhaled mannitol and cough in asthmatics with mucociliary dysfunction
    Evangelia Daviskas
    Departments of Respiratory and Sleep Medicine, 11 West Royal Prince Hospital, Camperdown, Sydney, NSW, Australia
    Respir Med 104:1645-53. 2010
    ..005). In conclusion, mannitol improved both mucociliary and cough clearance in asthmatics with mucociliary dysfunction and ineffective cough clearance. Clinical Trial registered with www.anzctr.org.au; Number ACTRN 12609001066279.aspx...
  18. doi request reprint Effect of mannitol and repetitive coughing on the sputum properties in bronchiectasis
    Evangelia Daviskas
    Department of Respiratory and Sleep Medicine, Royal Prince Alfred Hospital, 11 West, Missenden Road, Camperdown, Sydney, NSW 2050, Australia
    Respir Med 104:371-7. 2010
    ..Changes in sputum properties do not predict efficacy of mucociliary and cough clearance...
  19. pmc The safety and efficacy of inhaled dry powder mannitol as a bronchial provocation test for airway hyperresponsiveness: a phase 3 comparison study with hypertonic (4.5%) saline
    John D Brannan
    Department of Respiratory Medicine, 11 West, Royal Prince Alfred Hospital, Camperdown NSW 2050, Australia
    Respir Res 6:144. 2005
    ..The safety and the efficacy of mannitol (M) as a BPT to measure airway hyperresponsiveness were compared to hypertonic (4.5%) saline (HS) in people both with and without signs and symptoms of asthma...
  20. ncbi request reprint Mucociliary clearance in patients with chronic asthma: effects of beta agonists
    Evangelia Daviskas
    Department of Respiratory Medicine, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia
    Respirology 10:426-35. 2005
    ..We investigated baseline MCC and the acute effect of terbutaline in chronic asthmatics with sputum production while on long-term treatment with salmeterol in combination with inhaled corticosteroids (ICS)...
  21. ncbi request reprint Inhaled mannitol improves lung function in cystic fibrosis
    Anna Jaques
    Department of Clinical Research, Pharmaxis Ltd, Frenchs Forest, NSW, Australia
    Chest 133:1388-96. 2008
    ..To this end, this study examined the efficacy and safety of therapy with inhaled mannitol over a 2-week period...
  22. doi request reprint Acute effects of beclomethasone on hyperpnea-induced bronchoconstriction
    Pascale Kippelen
    Department of Respiratory and Sleep Medicine, Royal Prince Alfred Hospital, Camperdown, NSW Australia
    Med Sci Sports Exerc 42:273-80. 2010
    ..The aim of this study was to assess whether a single high dose of beclomethasone dipropionate (BDP) could blunt mast cell activation and bronchoconstriction after eucapnic voluntary hyperpnea (EVH)...
  23. ncbi request reprint Inhaled mannitol for the treatment of mucociliary dysfunction in patients with bronchiectasis: effect on lung function, health status and sputum
    Evangelia Daviskas
    Department of Respiratory Medicine, Royal Prince Alfred Hospital, Sydney, NSW, Australia
    Respirology 10:46-56. 2005
    ..Inhaled mannitol increases mucus clearance in patients with bronchiectasis by an unclear mechanism. The effect of mannitol on lung function, health status and sputum properties was investigated...
  24. pmc Reproducibility of the airway response to an exercise protocol standardized for intensity, duration, and inspired air conditions, in subjects with symptoms suggestive of asthma
    Sandra D Anderson
    Department of Respiratory and Sleep Medicine, 11 West, Royal Prince Alfred Hospital, Missenden Road, Camperdown, NSW 2050, Australia
    Respir Res 11:120. 2010
    ..This study examined reproducibility of % fall in FEV1 and area under the FEV1 time curve for 30 minutes in response to two exercise tests performed with the same intensity and duration of exercise, and inspired air conditions...
  25. ncbi request reprint Hyperosmolar agents and clearance of mucus in the diseased airway
    Evangelia Daviskas
    Department of Respiratory Medicine, Royal Prince Alfred Hospital, Camperdown, Sydney, NSW, Australia
    J Aerosol Med 19:100-9. 2006
    ..Further studies of the long-term clinical effect of hyperosmolar agents are needed...
  26. ncbi request reprint Indirect challenge tests: Airway hyperresponsiveness in asthma: its measurement and clinical significance
    Sandra D Anderson
    Royal Prince Alfred Hospital, Department of Respiratory and Sleep Medicine, Sydney Medical School, University of Sydney, Camperdown, NSW, Australia
    Chest 138:25S-30S. 2010
    ..Indirect challenges are appropriate to inform further on both the pathogenesis of asthma and the role of antiinflammatory agents in its treatment...
  27. doi request reprint Sodium cromoglycate and eformoterol attenuate sensitivity and reactivity to inhaled mannitol in subjects with bronchiectasis
    Peter J Briffa
    Department of Respiratory and Sleep Medicine, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia
    Respirology 16:161-6. 2011
    ..The aim of this study was to investigate if pre-medicating with either sodium cromoglycate (SCG) or eformoterol could inhibit this reduction in FEV1...
  28. ncbi request reprint Provocative challenges to help diagnose and monitor asthma: exercise, methacholine, adenosine, and mannitol
    Sandra D Anderson
    Department of Respiratory and Sleep Medicine, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia
    Curr Opin Pulm Med 14:39-45. 2008
    ..To review bronchial provocations tests used in the measurement of bronchial hyperresponsiveness to help in the diagnosis of asthma...
  29. ncbi request reprint Long-acting beta 2-adrenoceptor agonists and exercise-induced asthma: lessons to guide us in the future
    Sandra D Anderson
    Department of Respiratory Medicine, Royal Prince Alfred Hospital, Camperdown, Sydney, NSW, Australia
    Paediatr Drugs 6:161-75. 2004
    ..If this percentage is significant then we may need to reconsider the position of LABAs in the treatment of children with asthma who regularly perform strenuous physical activity...
  30. ncbi request reprint Responses to bronchial challenge submitted for approval to use inhaled beta2-agonists before an event at the 2002 Winter Olympics
    Sandra D Anderson
    Department of Respiratory Medicine, Royal Prince Alfred Hospital, Camperdown, NSW, Australia
    J Allergy Clin Immunol 111:45-50. 2003
    ..7% at Los Angeles (1984) to 5.5% at Sydney (2000). For Salt Lake City (2002), the International Olympic Committee requested objective evidence to use beta2-agonists for asthma or exercise-induced asthma (EIA)...
  31. ncbi request reprint Inhaled mannitol changes the sputum properties in asthmatics with mucus hypersecretion
    Evangelia Daviskas
    Department of Respiratory Medicine Royal Prince Alfred Hospital, Sydney, New South Wales, Australia
    Respirology 12:683-91. 2007
    ..Inhaled mannitol facilitates clearance of mucus. This study investigated the changes in the physical properties of sputum in response to mannitol in asthmatics with chronic cough and sputum production...
  32. ncbi request reprint Assessment of EIB: What you need to know to optimize test results
    Sandra D Anderson
    Department of Respiratory and Sleep Medicine, Royal Prince Alfred Hospital, Camperdown, New South Wales 2050, Missenden Road, Australia
    Immunol Allergy Clin North Am 33:363-80, viii. 2013
    ..The high rate of negative exercise test results has led to the development of surrogates to identify EIB in laboratory or office settings, including eucapnic voluntary hyperpnea of dry air and inhalation of hyperosmolar aerosols. ..
  33. ncbi request reprint Beta2-agonists and exercise-induced asthma
    Sandra D Anderson
    Department of Respiratory Medicine, Royal Prince Alfred Hospital, Camperdown, Australia
    Clin Rev Allergy Immunol 31:163-80. 2006
    ....
  34. ncbi request reprint How does exercise cause asthma attacks?
    Sandra D Anderson
    Department of Respiratory Medicine, Royal Prince Alfred Hospital, Camperdown, NSW, Australia
    Curr Opin Allergy Clin Immunol 6:37-42. 2006
    ..To emphasize that many inflammatory mediators are involved in exercise-induced bronchoconstriction and that some are found in both asthmatic and healthy subjects...
  35. ncbi request reprint Inhaled mannitol as a test for bronchial hyper-responsiveness
    John D Brannan
    Department of Respiratory and Sleep Medicine, 11 West, Royal Prince Alfred Hospital, Missenden Road, Camperdown, NSW 2050, Australia
    Expert Rev Respir Med 3:457-68. 2009
    ..Accordingly, the mannitol BPT provides a point-of-need tool to identify BHR to assist in the diagnosis of asthma...
  36. ncbi request reprint Osmotic stimuli increase clearance of mucus in patients with mucociliary dysfunction
    Evangelia Daviskas
    Department of Respiratory Medicine, Royal Prince Alfred Hospital, Sydney, Australia
    J Aerosol Med 15:331-41. 2002
    ..5%) was significantly increased compared to their respective controls (18.6 +/- 3.8% and 20.9 +/- 3.6%). These preliminary results suggest that long-term treatment with HS or mannitol may benefit patients with mucociliary dysfunction...
  37. ncbi request reprint Prediction of treatment-response to inhaled corticosteroids by mannitol-challenge test in COPD. A proof of concept
    Jorg D Leuppi
    Pneumology, Department of Internal Medicine, University Hospital, Petersgraben 4, Basel CH 4031, Switzerland
    Pulm Pharmacol Ther 18:83-8. 2005
    ..There are no predictors known that can identify COPD patients who will respond to treatment with ICS...
  38. ncbi request reprint Field exercise vs laboratory eucapnic voluntary hyperventilation to identify airway hyperresponsiveness in elite cold weather athletes
    Kenneth W Rundell
    Marywood University, Scranton, PA 18509 4742, USA
    Chest 125:909-15. 2004
    ..The objective was to compare the change in FEV(1) provoked by EVH with that provoked by exercise in cold weather athletes...
  39. ncbi request reprint Questionnaire responses that predict airway response to hypertonic saline
    Jorg D Leuppi
    Woolcock Institute of Medical Research, University of Sydney, Sydney, Australia
    Respiration 72:52-60. 2005
    ..Airway hyperresponsiveness to hypertonic saline (HS) is associated with airway inflammation. We investigated if responsiveness to HS was predicted by asthma symptoms in the last 3 months...
  40. ncbi request reprint Dissociation in the effect of nedocromil on mannitol-induced cough or bronchoconstriction in asthmatic subjects
    Heikki O Koskela
    Department of Respiratory Medicine, Kuopio University Hospital, Kuopio, Finland
    Respirology 10:442-8. 2005
    ..Nedocromil sodium greatly attenuates mannitol-induced bronchoconstriction. Knowledge about the effect of nedocromil on mannitol-provoked cough might, therefore, clarify the mechanisms of this response...
  41. ncbi request reprint Responsiveness to three bronchial provocation tests in patients with asthma
    Heikki O Koskela
    Department of Respiratory Medicine, Kuopio University Hospital, PL 1777, 70210 Kuopio, Finland
    Chest 124:2171-7. 2003
    ..To compare a new bronchial provocation test, the mannitol challenge, with cold air and histamine challenges to demonstrate airway hyperresponsiveness (AHR) in patients with difficult-to-diagnose asthma...
  42. ncbi request reprint Bronchial provocation tests: the rationale for using inhaled mannitol as a test for airway hyperresponsiveness
    Jorg D Leuppi
    Respiratory Medicine, Department of Internal Medicine, University Hospital, Basel, Switzerland
    Swiss Med Wkly 132:151-8. 2002
    ..Should this BPT become more readily available it would be the first to provide a common operating standard for use in the laboratory, office, or field...
  43. ncbi request reprint Airway reactivity to inhaled mannitol in cigarette smokers: a longitudinal study
    Daiana Stolz
    Pulmonary Medicine and Respiratory Cell Research and Hospital Pharmacy, University Hospital Basel, Switzerland
    Respir Med 101:1470-6. 2007
    ..AHR to mannitol is quite common in smokers compared to non-smokers and decreases significantly after smoking cessation. Thus, the mannitol test may be sensitive to non-asthmatic inflammation of the airways...
  44. ncbi request reprint Exercise in elite summer athletes: Challenges for diagnosis
    Karen Holzer
    Department of Allergy, Asthma and Clinical Immunology, Alfred Hospital and Monash University, Prahran, Australia
    J Allergy Clin Immunol 110:374-80. 2002
    ..Such measurements could include bronchial provocation with methacholine, with eucapnic voluntary hyperpnea (EVH) of dry air (a surrogate for exercise), or both...
  45. ncbi request reprint Sensitivity and validity of three bronchial provocation tests to demonstrate the effect of inhaled corticosteroids in asthma
    Heikki O Koskela
    Department of Respiratory Medicine, Kuopio University Hospital, Kuopio, Finland
    Chest 124:1341-9. 2003
    ..To compare the sensitivity and validity of mannitol, histamine, and cold air challenges to demonstrate the effect of inhaled corticosteroids (ICS) in asthma...
  46. ncbi request reprint Mannitol as a challenge test to identify exercise-induced bronchoconstriction in elite athletes
    Karen Holzer
    Department of Allergy, Alfred Hospital and Monash University, Prahran, Victoria, Australia
    Am J Respir Crit Care Med 167:534-7. 2003
    ..Mannitol had a sensitivity of 96% and specificity of 92% to identify a positive response to EVH and, as such, could be used as an alternative to EVH to identify EIB...
  47. doi request reprint Asthma and the elite athlete: summary of the International Olympic Committee's consensus conference, Lausanne, Switzerland, January 22-24, 2008
    Kenneth D Fitch
    School of Sports Science, Exercise and Health, Faculty of Life Sciences, University of Western Australia, Crawley, Australia
    J Allergy Clin Immunol 122:254-60, 260.e1-7. 2008
    ..The policy of requiring Olympic athletes to demonstrate the presence of asthma, exercise-induced bronchoconstriction, or AHR to be approved to inhale beta(2)-agonists will continue...
  48. pmc The effects of histamine and leukotriene receptor antagonism on nasal mannitol challenge in allergic rhinitis
    Daniel K C Lee
    Asthma and Allergy Research Group, Department of Clinical Pharmacology and Therapeutics, Ninewells Hospital and Medical School, University of Dundee, Dundee DD1 9SY, UK
    Br J Clin Pharmacol 55:639-42. 2003
    ..It is unclear as to which mediators are involved in mediating the response to nasal mannitol challenge, a novel osmotic stimulus...
  49. ncbi request reprint Coughing during mannitol challenge is associated with asthma
    Heikki O Koskela
    Department of Respiratory Medicine Drs Koskela and Hyvärinen, Kuopio University Hospital, Kuopio, Finland
    Chest 125:1985-92. 2004
    ..To define whether coughing during mannitol challenge is a nonspecific side effect of this challenge or is associated with asthma...