Osvaldo P Almeida

Summary

Affiliation: University of Western Australia
Country: Australia

Publications

  1. ncbi Current experiences and educational preferences of general practitioners and staff caring for people with dementia living in residential facilities
    Christopher Beer
    Western Australian Centre for Health and Ageing, Western Australian Institute for Medical Research, Perth, Australia
    BMC Geriatr 9:36. 2009
  2. ncbi One year follow-up study of the association between chemical castration, sex hormones, beta-amyloid, memory and depression in men
    Osvaldo P Almeida
    School of Psychiatry and Clinical Neurosciences, University of Western Australia, Mail Point M573 Level 6, Ainslie House, Royal Perth Hospital, 35 Stirling Highway, Perth, WA 6009, Australia
    Psychoneuroendocrinology 29:1071-81. 2004
  3. ncbi Contribution of the MTHFR gene to the causal pathway for depression, anxiety and cognitive impairment in later life
    Osvaldo P Almeida
    School of Psychiatry and Clinical Neurosciences, University of Western Australia, 35 Stirling Highway, Crawley, Perth, WA 6009, Australia
    Neurobiol Aging 26:251-7. 2005
  4. ncbi [Bipolar disorder with late onset: an organic variety of mood disorder?]
    Osvaldo P Almeida
    Escola de Psiquiatria e Neurociências Clínicas, Universidade da Austrália Ocidental, Australia
    Rev Bras Psiquiatr 26:27-30. 2004
  5. ncbi Association between physiological serum concentration of estrogen and the mental health of community-dwelling postmenopausal women age 70 years and over
    Osvaldo P Almeida
    UWA School of Psychiatry and Clinical Neurosciences M573, Level 6, Ainslie House, Royal Perth Hospital, 35 Stirling Highway, Crawley, Perth, WA 6009, Australia
    Am J Geriatr Psychiatry 13:142-9. 2005
  6. ncbi Depression and smoking amongst older general practice patients
    Osvaldo P Almeida
    School of Psychiatry and Clinical Neurosciences M573, University of Western Australia, 35 Stirling Highway, Crawley, Perth, WA 6009, Australia
    J Affect Disord 86:317-21. 2005
  7. ncbi Association between hormone replacement therapy and dementia: is it time to forget?
    Osvaldo P Almeida
    School of Psychiatry and Clinical Neurosciences, University of Western Australia and Royal Perth Hospital, Perth, Western Australia
    Int Psychogeriatr 17:155-64. 2005
  8. ncbi Preventing depression after stroke: Results from a randomized placebo-controlled trial
    Osvaldo P Almeida
    Unit of Geriatric Psychiatry, Royal Perth Hospital and University of Western Australia, Perth, Australia
    J Clin Psychiatry 67:1104-9. 2006
  9. ncbi Dementia associated with infectious diseases
    Osvaldo P Almeida
    University of Western Australia, School of Psychiatry and Clinical Neurosciences, Mail Delivery Point M573, 35 Stirling Highway, Crawley, Perth, WA 6009, Australia
    Int Psychogeriatr 17:S65-77. 2005
  10. ncbi Successful mental health aging: results from a longitudinal study of older Australian men
    Osvaldo P Almeida
    School of Psychiatry and Clinical Neurosciences, University of Western Australia, Royal Perth Hospital, Perth, WA 6009, Australia
    Am J Geriatr Psychiatry 14:27-35. 2006

Detail Information

Publications93

  1. ncbi Current experiences and educational preferences of general practitioners and staff caring for people with dementia living in residential facilities
    Christopher Beer
    Western Australian Centre for Health and Ageing, Western Australian Institute for Medical Research, Perth, Australia
    BMC Geriatr 9:36. 2009
    ..We sought to determine participation in dementia education, perceived levels of current knowledge regarding dementia, perceived unmet educational needs, current barriers, facilitators and preferences for dementia education...
  2. ncbi One year follow-up study of the association between chemical castration, sex hormones, beta-amyloid, memory and depression in men
    Osvaldo P Almeida
    School of Psychiatry and Clinical Neurosciences, University of Western Australia, Mail Point M573 Level 6, Ainslie House, Royal Perth Hospital, 35 Stirling Highway, Perth, WA 6009, Australia
    Psychoneuroendocrinology 29:1071-81. 2004
    ..The performance of subjects on the WL test was negatively correlated with plasma levels of Abeta, but the clinical significance of this finding remains to be determined...
  3. ncbi Contribution of the MTHFR gene to the causal pathway for depression, anxiety and cognitive impairment in later life
    Osvaldo P Almeida
    School of Psychiatry and Clinical Neurosciences, University of Western Australia, 35 Stirling Highway, Crawley, Perth, WA 6009, Australia
    Neurobiol Aging 26:251-7. 2005
    ..These results indicate that, in isolation, the MTHFR C677T gene variation does not play an important role in the modulation of mood and cognitive performance in later life...
  4. ncbi [Bipolar disorder with late onset: an organic variety of mood disorder?]
    Osvaldo P Almeida
    Escola de Psiquiatria e Neurociências Clínicas, Universidade da Austrália Ocidental, Australia
    Rev Bras Psiquiatr 26:27-30. 2004
    ..It concludes that the split of bipolar disorder according to age at onset is artificial, and lacks clinical significance and epidemiological support...
  5. ncbi Association between physiological serum concentration of estrogen and the mental health of community-dwelling postmenopausal women age 70 years and over
    Osvaldo P Almeida
    UWA School of Psychiatry and Clinical Neurosciences M573, Level 6, Ainslie House, Royal Perth Hospital, 35 Stirling Highway, Crawley, Perth, WA 6009, Australia
    Am J Geriatr Psychiatry 13:142-9. 2005
    ..The authors investigated the association between physiological levels of estrogen and mood/cognitive functioning among older postmenopausal women...
  6. ncbi Depression and smoking amongst older general practice patients
    Osvaldo P Almeida
    School of Psychiatry and Clinical Neurosciences M573, University of Western Australia, 35 Stirling Highway, Crawley, Perth, WA 6009, Australia
    J Affect Disord 86:317-21. 2005
    ..This study was designed to investigate the association between smoking and depression in people aged 60 years or over...
  7. ncbi Association between hormone replacement therapy and dementia: is it time to forget?
    Osvaldo P Almeida
    School of Psychiatry and Clinical Neurosciences, University of Western Australia and Royal Perth Hospital, Perth, Western Australia
    Int Psychogeriatr 17:155-64. 2005
    ....
  8. ncbi Preventing depression after stroke: Results from a randomized placebo-controlled trial
    Osvaldo P Almeida
    Unit of Geriatric Psychiatry, Royal Perth Hospital and University of Western Australia, Perth, Australia
    J Clin Psychiatry 67:1104-9. 2006
    ..We designed this study to determine whether the daily treatment of nondepressed acute stroke patients with sertraline reduced the incidence of depression at follow-up...
  9. ncbi Dementia associated with infectious diseases
    Osvaldo P Almeida
    University of Western Australia, School of Psychiatry and Clinical Neurosciences, Mail Delivery Point M573, 35 Stirling Highway, Crawley, Perth, WA 6009, Australia
    Int Psychogeriatr 17:S65-77. 2005
    ....
  10. ncbi Successful mental health aging: results from a longitudinal study of older Australian men
    Osvaldo P Almeida
    School of Psychiatry and Clinical Neurosciences, University of Western Australia, Royal Perth Hospital, Perth, WA 6009, Australia
    Am J Geriatr Psychiatry 14:27-35. 2006
    ..The authors investigated the associations of medical and lifestyle factors with the mental health of men in their 80s...
  11. ncbi A 20-week randomized controlled trial of estradiol replacement therapy for women aged 70 years and older: effect on mood, cognition and quality of life
    Osvaldo P Almeida
    School of Psychiatry and Clinical Neurosciences, The University of Western Australia M573, 35 Stirling Highway, Crawley, and Department of Psychiatry, Royal Perth Hospital, Perth, WA, Australia
    Neurobiol Aging 27:141-9. 2006
    ..Other more efficacious and safer interventions need to be devised with the aim of improving the mental state and quality of life of older women...
  12. ncbi [Mini mental state examination and the diagnosis of dementia in Brazil]
    O P Almeida
    Departamento de Saude Mental, Santa Casa de Sao Paulo
    Arq Neuropsiquiatr 56:605-12. 1998
    ..8% and specificity of 75.4%. The evaluation of elderly subjects with the MMSE should take education into account, and different cut-off points should be used accordingly as a guideline to the diagnosis of dementia...
  13. ncbi Sleep complaints among older general practice patients: association with depression
    Osvaldo P Almeida
    School of Psychiatry and Clinical Neurosciences, University of Western Australia, Perth
    Br J Gen Pract 55:864-6. 2005
    ..GPs should consider screening for the presence of depressive symptoms whenever older adults complain of sleep difficulties...
  14. ncbi Sex playing with the mind. Effects of oestrogen and testosterone on mood and cognition
    O P Almeida
    University of Western Australia UWA, Department of Psychiatry and Behavioural Science, Perth, Australia
    Arq Neuropsiquiatr 57:701-6. 1999
    ..If future studies prove this to be true, hormone replacement therapy should have a major impact on the physical and mental health of older people in the years to come...
  15. ncbi [Psychiatric symptoms among patients with dementia seen in an ambulatory service]
    O P Almeida
    Department of Psychiatry and Behavioural Science, University of Western Australia
    Arq Neuropsiquiatr 57:937-43. 1999
    ..The assessment of patients with dementia should always include a detailed psychiatric examination, as the detection and treatment of such symptoms may contribute to decrease the stress of patients and the burden on carers...
  16. ncbi [Perception of cognitive deficits and behavior disorders in patients with Alzheimer's disease]
    O P Almeida
    Departamento de Saude Mental, Santa Casa de Sao Paulo
    Arq Neuropsiquiatr 58:292-9. 2000
    ..In addition, our data shows that this lack of awareness is not influenced by the severity of cognitive impairment or the presence of depressive symptoms...
  17. ncbi Sleep complaints among the elderly: results from a survey in a psychogeriatric outpatient clinic in Brazil
    O P Almeida
    Department of Mental Health, Santa Casa de Sao Paulo, Brazil
    Int Psychogeriatr 11:47-56. 1999
    ..Nonetheless, only sparse information is available on the clinical characteristics of elderly persons with insomnia...
  18. ncbi Sex hormones and their impact on dementia and depression: a clinical perspective
    O P Almeida
    Department of Psychiatry and Behavioural Science, University of Western Australia, Perth, WA 6847, Australia
    Expert Opin Pharmacother 2:527-35. 2001
    ..At present, there is not enough hard data to support the use of sex hormones and DHEA for the treatment of depression or memory deficits...
  19. ncbi The mind of a failing heart: a systematic review of the association between congestive heart failure and cognitive functioning
    O P Almeida
    Department of Psychiatry and Behavioural Science, University of Western Australia, Perth, Australia
    Intern Med J 31:290-5. 2001
    ..Early reports indicated that patients with CHF display deficits in memory and other intellectual abilities, although the clinical relevance of these findings remains unclear...
  20. ncbi Smoking as a risk factor for Alzheimer's disease: contrasting evidence from a systematic review of case-control and cohort studies
    Osvaldo P Almeida
    Department of Psychiatry and Behavioural Science, University of Western Australia, Perth, Australia
    Addiction 97:15-28. 2002
    ..To investigate the risk of Alzheimer's disease (AD) associated with smoking...
  21. ncbi [Treatment of Alzheimer' disease: critical evaluation of the use of anticholinesterase]
    O P Almeida
    Departamento de Saude Mental, Santa Casa de Sao Paulo
    Arq Neuropsiquiatr 56:688-96. 1998
    ..Factors that may interfere with patients' response to treatment are also discussed, as well as the limitations associated with the use of this class of drugs...
  22. ncbi Bipolar disorder: similarities and differences between patients with illness onset before and after 65 years of age
    Osvaldo P Almeida
    Department of Psychiatry and Behavioural Science, University of Western Australia, Perth, Australia
    Int Psychogeriatr 14:311-22. 2002
    ....
  23. ncbi [Reliability of the Brazilian version of the ++abbreviated form of Geriatric Depression Scale (GDS) short form]
    O P Almeida
    Department of Psychiatry and Behavioural Science of the University of Western Australia, Queen Elisabeth II Medical Centre, Nedlands, Perth, WA, Australia
    Arq Neuropsiquiatr 57:421-6. 1999
    ..In contrast, the GDS with 10 and 15 items produced consistent results in the assessment of elderly patients when total scores were used as clinical guidelines...
  24. ncbi Anxiety, depression, and comorbid anxiety and depression: risk factors and outcome over two years
    Osvaldo P Almeida
    School of Psychiatry and Clinical Neurosciences, University of Western Australia, Crawley, Perth, WA, Australia
    Int Psychogeriatr 24:1622-32. 2012
    ..This study aimed to determine: (1) the prevalence of depression, anxiety, and depression associated with anxiety (DA); (2) the risk factor profile of depression, anxiety, and DA; (3) the course of depression, anxiety, and DA over 24 months...
  25. ncbi The B-VITAGE trial: a randomized trial of homocysteine lowering treatment of depression in later life
    Andrew H Ford
    Western Australian Centre for Health and Ageing, Centre for Medical Research, University of Western Australia, Perth, Australia
    Trials 11:8. 2010
    ..We designed the B-VITAGE trial to determine whether adjunctive treatment with vitamins B6, B12 and folate increases the efficacy of standard antidepressant treatment...
  26. ncbi Dementia in residential care: education intervention trial (DIRECT); protocol for a randomised controlled trial
    Christopher D Beer
    WA Centre for Health and Ageing, Centre for Medical Research, Perth, Western Australia, Australia
    Trials 11:63. 2010
    ..The DIRECT study will determine if delivery of education to General Practitioners (GPs) and care staff improves the quality of life of residential care recipients with cognitive impairment...
  27. ncbi A randomized trial to reduce the prevalence of depression and self-harm behavior in older primary care patients
    Osvaldo P Almeida
    School of Psychiatry and Clinical Neurosciences, University of Western Australia, Perth, Australia
    Ann Fam Med 10:347-56. 2012
    ..We wanted to determine whether an educational intervention targeting general practitioners reduces the 2-year prevalence of depression and self-harm behavior among their older patients...
  28. ncbi Healthier lifestyle predicts higher circulating testosterone in older men: the Health In Men Study
    Bu B Yeap
    School of Medicine and Pharmacology, University of Western Australia, Fremantle Hospital, Fremantle, Australia
    Clin Endocrinol (Oxf) 70:455-63. 2009
    ..We sought to determine whether greater participation in healthy behaviours predicted reduced risk of subsequent lower circulating testosterone in older men...
  29. ncbi The association between C-reactive protein concentration and depression in later life is due to poor physical health: results from the Health in Men Study (HIMS)
    Osvaldo P Almeida
    WA Centre for Health and Ageing, University of Western Australia, Australia
    Psychol Med 37:1775-86. 2007
    ..This study aimed to investigate the association between high CRP concentration and depression while taking physical health into account...
  30. ncbi Higher free thyroxine levels predict increased incidence of dementia in older men: the Health in Men Study
    Bu B Yeap
    School of Medicine and Pharmacology, Centre for Medical Research, University of Western Australia, Crawley, Western Australia 6009, Australia
    J Clin Endocrinol Metab 97:E2230-7. 2012
    ..Both hypothyroidism and subclinical hyperthyroidism hinder cognitive function...
  31. ncbi Factors associated with self and informant ratings of the quality of life of people with dementia living in care facilities: a cross sectional study
    Christopher Beer
    WA Centre for Health and Ageing, Centre for Medical Research, Perth, Western Australia, Australia
    PLoS ONE 5:e15621. 2010
    ..We undertook the present study to describe and determine the factors associated with ratings of the quality of life of a cohort of people with dementia living in a residential care facility...
  32. ncbi Homocysteine and depression in later life
    Osvaldo P Almeida
    FRANZCP, Western Australian Centre for Health and Ageing, University of Western Australia, Mail Box M573, 35 Stirling Hwy, Crawley, WA 6009, Australia
    Arch Gen Psychiatry 65:1286-94. 2008
    ..Genetic association studies are not prone to the same sources of error and offer an opportunity to explore the consistency and external validity of this association...
  33. ncbi Older men who use computers have lower risk of dementia
    Osvaldo P Almeida
    School of Psychiatry and Clinical Neurosciences, University of Western Australia, Perth, Western Australia, Australia
    PLoS ONE 7:e44239. 2012
    ..To determine if older men who use computers have lower risk of developing dementia...
  34. ncbi Low free testosterone predicts mortality from cardiovascular disease but not other causes: the Health in Men Study
    Zoe Hyde
    Western Australian Centre for Health and Ageing, University of Western Australia, 35 Stirling Highway, Crawley, Western Australia 6009, Australia
    J Clin Endocrinol Metab 97:179-89. 2012
    ..Low testosterone is associated with all-cause mortality, but the relationship with cause-specific mortality is uncertain...
  35. ncbi Falls, injuries from falls, health related quality of life and mortality in older adults with vision and hearing impairment--is there a gender difference?
    Derrick Lopez
    Western Australian Centre for Health and Ageing WACHA, Centre for Medical Research, The University of Western Australia, Nedlands, Western Australia, Australia
    Maturitas 69:359-64. 2011
    ..Our objective was to determine if there are gender differences in the associations between visual and hearing impairment and these outcomes...
  36. ncbi Effect of physical activity on cognitive function in older adults at risk for Alzheimer disease: a randomized trial
    Nicola T Lautenschlager
    WA Centre for Health and Ageing, University of Western Australia, Melbourne, Australia
    JAMA 300:1027-37. 2008
    ..Many observational studies have shown that physical activity reduces the risk of cognitive decline; however, evidence from randomized trials is lacking...
  37. ncbi Cognitive activity for the treatment of older adults with mild Alzheimer's disease (AD)--PACE AD: study protocol for a randomised controlled trial
    Mandy R Vidovich
    Western Australia Centre for Health and Ageing WACHA, School of Psychiatry and Clinical Neurosciences and Centre for Medical Research, University of Western Australia and Royal Perth Hospital, Australia
    Trials 12:47. 2011
    ....
  38. ncbi Elevated homocysteine is associated with poorer self-perceived physical health in older men: the Health in Men Study
    Yuen Y E Wong
    Western Australian Centre for Health and Ageing WACHA, Centre for Medical Research, Perth, WA, Australia
    Maturitas 73:158-63. 2012
    ....
  39. ncbi Higher free thyroxine levels are associated with frailty in older men: the Health In Men Study
    Bu B Yeap
    School of Medicine and Pharmacology, University of Western Australia, Western Australia, Australia
    Clin Endocrinol (Oxf) 76:741-8. 2012
    ..Some symptoms of frailty overlap those of thyroid dysfunction, but it is unclear whether differences in thyroid status influence risk of frailty. We evaluated associations between thyroid status and frailty in older men...
  40. ncbi Plasma homocysteine and MTHFRC677T polymorphism as risk factors for incident dementia
    Andrew H Ford
    School of Psychiatry and Clinical Neurosciences M573, University of Western Australia, 35 Stirling Highway, Crawley, WA 6009, Australia
    J Neurol Neurosurg Psychiatry 83:70-5. 2012
    ..The authors designed this longitudinal study to determine if high tHcy and the MTHFR C677T polymorphism increase the risk of incident dementia among older men...
  41. ncbi A cluster-randomised trial of staff education to improve the quality of life of people with dementia living in residential care: the DIRECT study
    Christopher Beer
    WA Centre for Health and Ageing, Centre for Medical Research, Perth, Western Australia, Australia
    PLoS ONE 6:e28155. 2011
    ....
  42. ncbi Two-year course of cognitive function and mood in adults with congestive heart failure and coronary artery disease: the Heart-Mind Study
    Osvaldo P Almeida
    School of Psychiatry and Clinical Neurosciences, University of Western Australia, Perth, Australia
    Int Psychogeriatr 24:38-47. 2012
    ..We designed this study to determine if adults with CHF show evidence of cognitive decline compared with adults with and without coronary artery disease (CAD)...
  43. ncbi Complaints of difficulty to fall asleep increase the risk of depression in later life: the health in men study
    Osvaldo P Almeida
    School of Psychiatry and Clinical Neurosciences, University of Western Australia, Perth, WA 6009, Australia
    J Affect Disord 134:208-16. 2011
    ..To determine if complaints of poor sleep are associated with incident depression in older men...
  44. ncbi Association between lifestyle factors and mental health measures among community-dwelling older women
    Kellie Cassidy
    School of Psychiatry, and Clinical Neurosciences, University of Western Australia, Perth, Australia
    Aust N Z J Psychiatry 38:940-7. 2004
    ..Randomised clinical trials should be now designed to clarify whether management of lifestyle factors reduces the incidence of mood disorders and cognitive impairment in later life...
  45. ncbi B-vitamins reduce the long-term risk of depression after stroke: The VITATOPS-DEP trial
    Osvaldo P Almeida
    School of Psychiatry and Clinical Neurosciences, University of Western Australia, Crawley, Perth, WA, Australia
    Ann Neurol 68:503-10. 2010
    ..The purpose of this research was to determine if treatment with B-vitamins reduces the hazard of poststroke depression compared with placebo...
  46. ncbi B-vitamins reduce plasma levels of beta amyloid
    Leon Flicker
    School of Medicine and Pharmacology, University of Western Australia, Australia
    Neurobiol Aging 29:303-5. 2008
    ..E.) increase of A beta 40 was 7.0 pg/ml (8.4) in the vitamin group (4.9%), and 26.8 pg/ml (7.7) (18.5%) in the placebo group. We conclude that B vitamins may decrease the plasma level of A beta 40 and have a role in the prevention of AD...
  47. ncbi Socioeconomic disadvantage increases risk of prevalent and persistent depression in later life
    Osvaldo P Almeida
    School of Psychiatry and Clinical Neurosciences, University of Western Australia, Perth, WA, Australia
    J Affect Disord 138:322-31. 2012
    ..This study aimed to determine the independent association between socioeconomic disadvantage and depression...
  48. ncbi Alcohol use and mortality in older men and women
    Kieran A McCaul
    Western Australian Centre for Health and Ageing, University of Western Australia, 35 Stirling Highway, Crawley, Western Australia 6009, Australia
    Addiction 105:1391-400. 2010
    ..To compare the effect of alcohol intake on 10-year mortality for men and women over the age of 65 years...
  49. ncbi Low free testosterone predicts frailty in older men: the health in men study
    Zoe Hyde
    Western Australian Centre for Health and Ageing M570, University of Western Australia, 35 Stirling Highway, Crawley, Western Australia 6009, Australia
    J Clin Endocrinol Metab 95:3165-72. 2010
    ..The prevalence of frailty increases, whereas testosterone decreases, as men age. Low testosterone may be a risk factor for development of this syndrome...
  50. ncbi 24-month effect of smoking cessation on cognitive function and brain structure in later life
    Osvaldo P Almeida
    Western Australian Centre for Health and Ageing, Centre for Medical Research, University of Western Australia, Crawley, Perth, WA, Australia
    Neuroimage 55:1480-9. 2011
    ..We completed this trial to determine if smoking cessation decreases the progression of cognitive decline in later life...
  51. ncbi Premorbid personality traits are associated with post-stroke behavioral and psychological symptoms: a three-month follow-up study in Perth, Western Australia
    Kathryn R Greenop
    WA Centre for Health and Ageing, University of Western Australia, Perth, Australia
    Int Psychogeriatr 21:1063-71. 2009
    ..This study sought to investigate further the relationship between premorbid personality and a number of common post-stroke behavioral and psychological symptoms in a three-month follow-up study...
  52. ncbi Traditional risk factors for incident cardiovascular events have limited importance in later life compared with the health in men study cardiovascular risk score
    Christopher Beer
    Western Australian Centre for Health and Ageing, Centre for Medical Research, Western Australian Institute for Medical Research, Perth, Australia
    Stroke 42:952-9. 2011
    ..This study aimed to determine, among older men, the risk and independent significant baseline prognostic factors for first-ever stroke and MI...
  53. ncbi Lower testosterone levels predict incident stroke and transient ischemic attack in older men
    Bu B Yeap
    School of Medicine and Pharmacology, University of Western Australia, Crawley, WA 6009, Australia
    J Clin Endocrinol Metab 94:2353-9. 2009
    ..However, it is unclear whether lower testosterone levels predict major cardiovascular events...
  54. ncbi Prevalence of sexual activity and associated factors in men aged 75 to 95 years: a cohort study
    Zoe Hyde
    Western Australian Centre for Health and Ageing, Centre for Medical Research, Western Australian Institute for Medical Research, School of Medicine and Pharmacology, School of Psychiatry and Clinical Neurosciences, University of Western Australia, Crawley, Australia
    Ann Intern Med 153:693-702. 2010
    ..Knowledge about sexuality in elderly persons is limited, and normative data are lacking...
  55. ncbi Subjective memory complaints with and without objective memory impairment: relationship with risk factors for dementia
    Nicola T Lautenschlager
    School of Psychiatry and Clinical Neurosciences, University of Western Australia, 35 Stirling Highway, Crawley, Perth, WA 6009, Australia
    Am J Geriatr Psychiatry 13:731-4. 2005
    ....
  56. ncbi Vitamins B12, B6, and folic acid for onset of depressive symptoms in older men: results from a 2-year placebo-controlled randomized trial
    Andrew H Ford
    South Metropolitan Health Service, Perth, Australia
    J Clin Psychiatry 69:1203-9. 2008
    ..To examine whether use of vitamins B(12), B(6), and folate was associated with reduced severity of depressive symptoms and 2-year incidence of clinically significant depression...
  57. ncbi Association of cardiovascular risk factors and disease with depression in later life
    Osvaldo P Almeida
    Unit of Geriatric Psychiatry, University of Western Australia and Royal Perth Hospital, Perth, WA, Australia
    Am J Geriatr Psychiatry 15:506-13. 2007
    ..The objective of this study is to determine the association between established cardiovascular risk factors and depression among older men...
  58. ncbi Factors associated with dementia in Aboriginal Australians
    Kate Smith
    Western Australian Centre for Health and Ageing M570, Centre for Health Research, University of Western Australia, 35 Stirling Highway, Crawley, Perth, Western Australia 6009, Australia
    Aust N Z J Psychiatry 44:888-93. 2010
    ..This study was designed to determine the demographic, lifestyle and clinical factors associated with dementia in Aboriginal Australians living in the Kimberley region of Western Australia...
  59. ncbi Development and evaluation of an educational intervention for general practitioners and staff caring for people with dementia living in residential facilities
    Christopher Beer
    Western Australian Centre for Health and Ageing M570, Centre for Medical Research, The University of Western Australia, Crawley, Western Australia, Australia
    Int Psychogeriatr 23:221-9. 2011
    ..Small group education, which is flexible, individualized, practical and case-based, is sought. We aimed to develop educational interventions for GPs and RCF staff tailored to meet their perceived educational needs...
  60. ncbi Elevated LH predicts ischaemic heart disease events in older men: the Health in Men Study
    Zoe Hyde
    Western Australian Centre for Health and Ageing M570, Centre for Medical Research, Western Australian Institute for Medical Research School of Medicine and Pharmacology School of Surgery, University of Western Australia, 35 Stirling Highway, Crawley, Western Australia 6009, Australia
    Eur J Endocrinol 164:569-77. 2011
    ..However, it is uncertain whether the age-related decline in testosterone is associated with ischaemic heart disease (IHD) events...
  61. ncbi Thyroid hormones and depression: the Health in Men study
    Osvaldo P Almeida
    WA Centre for Health and Ageing, Centre for Medical Research, University of Western Australia, Perth, WA
    Am J Geriatr Psychiatry 19:763-70. 2011
    ..Current practice guidelines suggest that thyroid function tests should be an integral part of the assessment of adults presenting with a depressive episode, although there is a paucity of data available to support such a recommendation...
  62. ncbi Latent Semantic Analysis: an improved method to measure cognitive performance in subjects of Non-English-Speaking-Background
    Nicola T Lautenschlager
    School of Psychiatry and Clinical Neurosciences, University of Western Australia
    J Clin Exp Neuropsychol 28:1381-7. 2006
    ..The results suggest that LSA is a more robust measure of cognitive function than traditional scoring methods and may therefore improve the validity of cognitive assessment results on subjects of NESB...
  63. ncbi Quality use of medicines and health outcomes among a cohort of community dwelling older men: an observational study
    Christopher Beer
    Western Australian Centre for Health and Ageing, Centre for Medical Research, Western Australian Institute for Medical Research, Perth, WA, Australia
    Br J Clin Pharmacol 71:592-9. 2011
    ..To determine the prevalence of potentially suboptimal medication use and association with adverse outcomes...
  64. ncbi Body adiposity in later life and the incidence of dementia: the health in men study
    Brian D Power
    Department of Psychiatry, Royal Perth Hospital, Perth, Western Australia, Australia
    PLoS ONE 6:e17902. 2011
    ..To determine if adiposity in later life increases dementia hazard...
  65. ncbi Awareness of cognitive deficits in older adults with cognitive-impairment-no-dementia (CIND): comparison with informant report
    Kathryn R Greenop
    Division of Population Sciences, Telethon Institute for Child Health Research, Center for Child Health Research, University of Western Australia, Subiaco, WA, Australia
    Alzheimer Dis Assoc Disord 25:24-33. 2011
    ..In addition, self-report of cognitive complaints may be at least as useful as informant report when screening community-dwelling older adults at risk of cognitive decline and dementia...
  66. ncbi Polymorphisms of the CRP gene inhibit inflammatory response and increase susceptibility to depression: the Health in Men Study
    Osvaldo P Almeida
    Western Australian Centre for Health and Ageing, Perth, WA, Australia
    Int J Epidemiol 38:1049-59. 2009
    ..The aim of this study is to determine if polymorphisms of SNPs rs1130864 and rs1205 are associated with prevalent depression...
  67. ncbi Homocysteine, grey matter and cognitive function in adults with cardiovascular disease
    Andrew H Ford
    Western Australian Centre for Health and Ageing, University of Western Australia, Perth, Western Australia, Australia
    PLoS ONE 7:e33345. 2012
    ..Elevated total plasma homocysteine (tHcy) has been associated with cognitive impairment, vascular disease and brain atrophy...
  68. ncbi Effectiveness of a smoking cessation intervention in older adults
    Robert J Tait
    School of Psychiatry and Clinical Neurosciences, University of Western Australia, Australia
    Addiction 102:148-55. 2007
    ....
  69. ncbi Higher serum free testosterone is associated with better cognitive function in older men, while total testosterone is not. The Health In Men Study
    Bu B Yeap
    School of Medicine and Pharmacology, University of Western Australia, Australia
    Clin Endocrinol (Oxf) 68:404-12. 2008
    ..To determine the relationship of total and free serum testosterone to cognitive performance in older men...
  70. ncbi In men older than 70 years, total testosterone remains stable while free testosterone declines with age. The Health in Men Study
    Bu B Yeap
    School of Medicine and Pharmacology, University of Western Australia, Crawley, Western Australia, Australia
    Eur J Endocrinol 156:585-94. 2007
    ..We sought to determine the distribution and associations of reduced testosterone concentrations in older men...
  71. ncbi Low free testosterone concentration as a potentially treatable cause of depressive symptoms in older men
    Osvaldo P Almeida
    WA Centre for Health and Ageing, University of Western Australia, Perth, Australia
    Arch Gen Psychiatry 65:283-9. 2008
    ..Serum concentrations of gonadal hormones have been associated with various measures of well-being, but it is unclear whether their association with mood is confounded by concurrent physical morbidity...
  72. ncbi Efficacy of B vitamins in lowering homocysteine in older men: maximal effects for those with B12 deficiency and hyperhomocysteinemia
    Leon Flicker
    School of Medicine and Pharmacology, University of Western Australia, Perth, Australia
    Stroke 37:547-9. 2006
    ..Previous studies, largely in younger individuals, have shown that B vitamins lowered tHcy by substantial amounts and that this effect is greater in people with higher tHcy and lower folate levels...
  73. ncbi Medical morbidity and severity of depression in a large primary care sample of older Australians: the DEPS-GP project
    Jon J Pfaff
    Western Australian Centre for Health and Ageing, Perth, WA, Australia
    Med J Aust 190:S75-80. 2009
    ..To estimate the prevalence of depression among older Australians with common medical morbidities, and to determine the association between poor physical health and depression in this age group...
  74. ncbi A randomized trial of early psychiatric intervention in residential care: impact on health outcomes
    Ria Kotynia-English
    School of Psychiatry and Clinical Neurosciences, University of Western Australia and Royal Perth Hospital, Perth, Western Australia
    Int Psychogeriatr 17:475-85. 2005
    ..More effective interventions to improve the health outcomes of older adults with psychological and behavioral disturbances admitted to residential care facilities are needed...
  75. ncbi Predictors of cognitive decline in older individuals with diabetes
    David G Bruce
    1School of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia, Australia
    Diabetes Care 31:2103-7. 2008
    ..The purpose of this study was to determine longitudinal predictors of cognitive decline in older individuals with diabetes who did not have dementia...
  76. ncbi Body mass index and survival in men and women aged 70 to 75
    Leon Flicker
    Western Australian Centre for Health and Ageing, Centre for Medical Research, Western Australian Institute for Medical Research, The University of Western Australia, 35 Stirling Highway, Crawley, Perth, Western Australia 6009
    J Am Geriatr Soc 58:234-41. 2010
    ..To examine in an older population all-cause and cause-specific mortality associated with underweight (body mass index (BMI)<18.5), normal weight (BMI 18.5-24.9), overweight (BMI 25.0-29.9), and obesity (BMI> or =30.0)...
  77. ncbi Healthy mental ageing
    Leon Flicker
    Department of Geriatric Medicine, School of Medicine and Pharmacology, University of Western Australia, Australia
    J Br Menopause Soc 12:92-6. 2006
    ....
  78. ncbi The PACE study: a randomised clinical trial of cognitive activity (CA) for older adults with mild cognitive impairment (MCI)
    Mandy R Vidovich
    Western Australia Centre for Health and Ageing, School of Psychiatry and Clinical Neurosciences, Perth, Western Australia, Australia
    Trials 10:114. 2009
    ..The Promoting Healthy Ageing with Cognitive Exercise (PACE) study has been designed to determine whether a cognitive activity intervention decreases the rate of cognitive decline amongst older adults with mild cognitive impairment (MCI)...
  79. ncbi Cognitive impairment, physical disability and depressive symptoms in older diabetic patients: the Fremantle Cognition in Diabetes Study
    David G Bruce
    School of Medicine and Pharmacology, University of Western Australia, Perth, Australia
    Diabetes Res Clin Pract 61:59-67. 2003
    ..To determine whether the prevalence of dementia, depression and/or disability in older diabetic subjects warrants an active screening approach by diabetes health care workers...
  80. ncbi Mortality associated with incident mental health disorders after stroke
    Osvaldo P Almeida
    WA Centre for Health and Aging, University of Western Australia, 35 Stirling Highway, Crawley, WA 6009, Australia
    Aust N Z J Psychiatry 41:274-81. 2007
    ..This study was designed to determine: (1) the incidence of first ever mental health disorder in amongst stroke patients; (2) the 10-year mortality associated with incident post-stroke mental health disorders...
  81. ncbi Relationship between quantity and frequency of alcohol use and indices of suicidal behavior in an elderly Australian sample
    Jon J Pfaff
    Western Australian Center for Health and Ageing, School of Psychiatry and Clinical Neurosciences, University of Western Australia in Perth, Australia
    Suicide Life Threat Behav 37:616-26. 2007
    ..The interaction between quantity and frequency of alcohol use was significant, suggesting that those who use alcohol less frequently but in greater quantities (i.e., binge drinking) are more likely to have a history of suicide attempts...
  82. ncbi Smoking is associated with reduced cortical regional gray matter density in brain regions associated with incipient Alzheimer disease
    Osvaldo P Almeida
    Western Australia Centre for Health and Ageing, School of Psychiatry and Clinical Neurosciences, University of Western Australia, 35 Stirling Highway, Perth, Western Australia 6009, Australia
    Am J Geriatr Psychiatry 16:92-8. 2008
    ..The authors designed this study to determine if older people who smoke have decreased gray matter density in brain regions associated with incipient AD...
  83. ncbi A cross-sectional analysis of factors that influence the detection of depression in older primary care patients
    Jon J Pfaff
    School of Psychiatry and Clinical Neurosciences, University of Western Australia, Unit Of Geriatric Psychiatry M573, 35 Stirling Highway, Crawley, Western Australia 6009, Australia
    Aust N Z J Psychiatry 39:262-5. 2005
    ..To determine the characteristics of depressed older patients whose mental health status is detected by their general practitioner (GP)...
  84. ncbi Physical activity and cognition in old age
    Nicola T Lautenschlager
    School of Psychiatry and Clinical Neurosciences, University of Western Australia, Perth, Western Australia, Australia
    Curr Opin Psychiatry 19:190-3. 2006
    ..This paper critically reviews the evidence in support of the association between exercise and cognitive decline/dementia, as reported by cohort studies or clinical trials...
  85. ncbi Latent semantic analysis: a new method to measure prose recall
    John C Dunn
    Department of Psychiatry and Behavioural Science, University of Western Australia, Nedlands, WA, Australia
    J Clin Exp Neuropsychol 24:26-35. 2002
    ..This suggests that LSA may serve as an improved measure of prose recall...
  86. ncbi Testosterone and dementia: too much ado about too little data
    Osvaldo P Almeida
    School of Psychiatry and Clinical Neurosciences, University of Western Australia, Royal Perth Hospital, Perth, Australia
    J Br Menopause Soc 9:107-10. 2003
    ..In conclusion, currently available evidence does not support the existence of a strong association between testosterone and cognitive function/AD...
  87. ncbi Identifying suicidal ideation among older adults in a general practice setting
    Jon J Pfaff
    School of Psychiatry and Clinical Neurosciences, University of Western Australia, RPH Ainslie House M573, Nedlands, WA 6009, Australia
    J Affect Disord 83:73-7. 2004
    ..The purpose of this study was to identify the clinical and demographic characteristics of older adults who are contemplating suicide and are in contact with a GP...
  88. ncbi Detecting suicidal ideation in older patients: identifying risk factors within the general practice setting
    Jon J Pfaff
    School of Psychiatry and Clinical Neurosciences, University of Western Australia, Crawley, Western Australia
    Br J Gen Pract 55:269-73. 2005
    ..GPs are the most frequently accessed health professional among suicidal individuals in the community...
  89. ncbi Dementia associated with alcohol and other drug use
    Gary K Hulse
    School of Psychiatry and Clinical Neurosciences, University of Western Australia, Australia
    Int Psychogeriatr 17:S109-27. 2005
    ..Health promotion programs designed to decrease tobacco smoking and "harmful" alcohol use (and possibly other drug use) may decrease the burden of cognitive impairment and perhaps dementia in later life...
  90. ncbi Inspection time in non-demented older adults with mild cognitive impairment
    Kathryn R Bonney
    Unit of Geriatric Psychiatry, University of Western Australia and Royal Perth Hospital, Australia
    Neuropsychologia 44:1452-6. 2006
    ..In combination with other clinical, neuropsychological and biological tests, IT may be a useful assessment tool for improving the identification of older adults at risk for clinically relevant cognitive decline...
  91. ncbi Obesity and metabolic syndrome increase the risk of incident depression in older men: the health in men study
    Osvaldo P Almeida
    Western Australian Centre for Health and Ageing, Western Australian Institute for Medical Research, Australia
    Am J Geriatr Psychiatry 17:889-98. 2009
    ....
  92. ncbi Higher luteinizing hormone is associated with poor memory recall: the health in men study
    Zoe Hyde
    Western Australian Institute for Medical Research, Australia
    J Alzheimers Dis 19:943-51. 2010
    ..These findings suggest a role for both androgens and gonadotropins in differing cognitive domains, and that gonadotropins may influence cognition independent of sex steroids...
  93. ncbi Depression, antidepressant use and mortality in later life: the Health In Men Study
    Osvaldo P Almeida
    Western Australia Centre for Health and Ageing, University of Western Australia, Perth, Western Australia, Australia
    PLoS ONE 5:e11266. 2010
    ..Depression is associated with increased mortality, but it is unclear if this relationship is dose-dependent and if it can be modified by treatment with antidepressants...