Richard J N Allcock

Summary

Affiliation: University of Western Australia
Country: Australia

Publications

  1. pmc Complete MHC haplotype sequencing for common disease gene mapping
    C Andrew Stewart
    Wellcome Trust Sanger Institute, Genome Campus, Hinxton, Cambridge CB10 1SA, United Kingdom
    Genome Res 14:1176-87. 2004
  2. ncbi request reprint High-Density SNP genotyping defines 17 distinct haplotypes of the TNF block in the Caucasian population: implications for haplotype tagging
    Richard J N Allcock
    School of Surgery and Pathology, University of Western Australia, QEII Medical Centre, Nedlands, Australia
    Hum Mutat 24:517-25. 2004
  3. doi request reprint Investigation of NOTCH4 coding region polymorphisms in sporadic inclusion body myositis
    Adrian P Scott
    School of Pathology and Laboratory Medicine, M504, University of Western Australia, Stirling Highway, Nedlands 6009, Perth, Australia
    J Neuroimmunol 250:66-70. 2012
  4. ncbi request reprint Polymorphisms at positions -22 and -348 in the promoter of the BAT1 gene affect transcription and the binding of nuclear factors
    Patricia Price
    School of Surgery and Pathology, University of Western Australia, Nedlands 6009, and Department of Clinical Immunology and Biochemical Genetics, Royal Perth Hospital, Perth 6001, Australia
    Hum Mol Genet 13:967-74. 2004
  5. ncbi request reprint Alleles of the proximal promoter of BAT1, a putative anti-inflammatory gene adjacent to the TNF cluster, reduce transcription on a disease-associated MHC haplotype
    Agnes M L Wong
    Department of Pathology, University of Western Australia, Nedlands 6009, Western Australia
    Genes Cells 8:403-12. 2003
  6. doi request reprint Recombination mapping of the susceptibility region for sporadic inclusion body myositis within the major histocompatibility complex
    Adrian P Scott
    School of Pathology and Laboratory Medicine, M504, University of Western Australia, Perth, Australia
    J Neuroimmunol 235:77-83. 2011
  7. pmc Mutations in KLHL40 are a frequent cause of severe autosomal-recessive nemaline myopathy
    Gianina Ravenscroft
    Western Australian Institute for Medical Research and the Centre for Medical Research, University of Western Australia, Nedlands, Western Australia 6009, Australia
    Am J Hum Genet 93:6-18. 2013
  8. doi request reprint The major histocompatibility complex: a paradigm for studies of the human genome
    Richard J N Allcock
    Lotterywest State Biomedical Facility Genomics, School of Pathology and Laboratory Medicine, University of Western Australia, Nedlands, Australia
    Methods Mol Biol 882:1-7. 2012
  9. ncbi request reprint A promoter polymorphism in the central MHC gene, IKBL, influences the binding of transcription factors USF1 and E47 on disease-associated haplotypes
    Alvin Boodhoo
    University of Mauritius, Reduit, Mauritius, Western Australia
    Gene Expr 12:1-11. 2004

Collaborators

Detail Information

Publications9

  1. pmc Complete MHC haplotype sequencing for common disease gene mapping
    C Andrew Stewart
    Wellcome Trust Sanger Institute, Genome Campus, Hinxton, Cambridge CB10 1SA, United Kingdom
    Genome Res 14:1176-87. 2004
    ....
  2. ncbi request reprint High-Density SNP genotyping defines 17 distinct haplotypes of the TNF block in the Caucasian population: implications for haplotype tagging
    Richard J N Allcock
    School of Surgery and Pathology, University of Western Australia, QEII Medical Centre, Nedlands, Australia
    Hum Mutat 24:517-25. 2004
    ..Using the control individuals, we defined a further six haplotypes that account for an additional 10% of donors. We show that the 17 haplotypes of the "TNF block" can be identified using 15 SNPs...
  3. doi request reprint Investigation of NOTCH4 coding region polymorphisms in sporadic inclusion body myositis
    Adrian P Scott
    School of Pathology and Laboratory Medicine, M504, University of Western Australia, Stirling Highway, Nedlands 6009, Perth, Australia
    J Neuroimmunol 250:66-70. 2012
    ..These NOTCH4 polymorphisms can be considered to be markers for sIBM susceptibility, but require further investigation to determine whether they are directly involved in the disease pathogenesis...
  4. ncbi request reprint Polymorphisms at positions -22 and -348 in the promoter of the BAT1 gene affect transcription and the binding of nuclear factors
    Patricia Price
    School of Surgery and Pathology, University of Western Australia, Nedlands 6009, and Department of Clinical Immunology and Biochemical Genetics, Royal Perth Hospital, Perth 6001, Australia
    Hum Mol Genet 13:967-74. 2004
    ..1 AH, whilst the reverse was observed with 336 bp fragments. This suggests BAT1 transcription on the 7.1 AH is modified by interactions involving DNA flanking positions -22 and -348...
  5. ncbi request reprint Alleles of the proximal promoter of BAT1, a putative anti-inflammatory gene adjacent to the TNF cluster, reduce transcription on a disease-associated MHC haplotype
    Agnes M L Wong
    Department of Pathology, University of Western Australia, Nedlands 6009, Western Australia
    Genes Cells 8:403-12. 2003
    ..We showed that BAT1 can reduce inflammatory cytokine production, supporting its candidacy as a disease gene. Here we examined the proximal promoter region of BAT1...
  6. doi request reprint Recombination mapping of the susceptibility region for sporadic inclusion body myositis within the major histocompatibility complex
    Adrian P Scott
    School of Pathology and Laboratory Medicine, M504, University of Western Australia, Perth, Australia
    J Neuroimmunol 235:77-83. 2011
    ..1AH-specific susceptibility region was defined, spanning 172 kb and encompassing three genes--HLA-DRB3, HLA-DRA and BTNL2. It is thus likely that 8.1AH-derived susceptibility to sIBM originates from at least one of these genes...
  7. pmc Mutations in KLHL40 are a frequent cause of severe autosomal-recessive nemaline myopathy
    Gianina Ravenscroft
    Western Australian Institute for Medical Research and the Centre for Medical Research, University of Western Australia, Nedlands, Western Australia 6009, Australia
    Am J Hum Genet 93:6-18. 2013
    ..Screening of KLHL40 should be a priority in individuals who are affected by autosomal-recessive NEM and who present with prenatal symptoms and/or contractures and in all Japanese individuals with severe NEM...
  8. doi request reprint The major histocompatibility complex: a paradigm for studies of the human genome
    Richard J N Allcock
    Lotterywest State Biomedical Facility Genomics, School of Pathology and Laboratory Medicine, University of Western Australia, Nedlands, Australia
    Methods Mol Biol 882:1-7. 2012
    ..This article provides a brief overview of the MHC highlighting some of the issues that must be considered when developing new methods and assays...
  9. ncbi request reprint A promoter polymorphism in the central MHC gene, IKBL, influences the binding of transcription factors USF1 and E47 on disease-associated haplotypes
    Alvin Boodhoo
    University of Mauritius, Reduit, Mauritius, Western Australia
    Gene Expr 12:1-11. 2004
    ..The restriction of IKBL expression to Jurkat cells is consistent with evidence that E47 is expressed in thymocytes and suggests IKBL may affect autoimmunity through an effect on T-cell selection...