Eleanor I Ager

Summary

Affiliation: University of Melbourne
Country: Australia

Publications

  1. pmc Expression and protein localisation of IGF2 in the marsupial placenta
    Eleanor I Ager
    Department of Zoology, The University of Melbourne, Melbourne, Victoria, 3010, Australia
    BMC Dev Biol 8:17. 2008
  2. pmc Evolution of the CDKN1C-KCNQ1 imprinted domain
    Eleanor I Ager
    Department of Zoology, The University of Melbourne, Melbourne, Victoria, 3010, Australia
    BMC Evol Biol 8:163. 2008
  3. doi request reprint The renin-angiotensin system and malignancy
    Eleanor I Ager
    Department of Surgery, Austin Health, University of Melbourne, Heidelberg, Victoria 3084, Australia
    Carcinogenesis 29:1675-84. 2008
  4. pmc Altered efficacy of AT1R-targeted treatment after spontaneous cancer cell-AT1R upregulation
    Eleanor I Ager
    The Department of Surgery, Austin Health, The University of Melbourne, Heidelberg, Vic, Australia
    BMC Cancer 11:274. 2011
  5. pmc Targeting the angiotensin II type 2 receptor (AT2R) in colorectal liver metastases
    Eleanor I Ager
    Department of Surgery, The University of Melbourne, Austin Health, Heidelberg, Victoria, Australia
    Cancer Cell Int 10:19. 2010
  6. pmc The renin angiotensin system regulates Kupffer cells in colorectal liver metastases
    Shu Wen Wen
    Department of Surgery, The University of Melbourne, Austin Health, Heidelberg, Victoria, Australia
    Cancer Biol Ther 14:720-7. 2013
  7. doi request reprint Genomic imprinting in marsupial placentation
    Marilyn B Renfree
    Department of Zoology, ARC Centre of Excellence for Kangaroo Genomics, The University of Melbourne, Melbourne, Victoria 3010, Australia
    Reproduction 136:523-31. 2008
  8. pmc Changes in the renin angiotensin system during the development of colorectal cancer liver metastases
    Jaclyn H Neo
    Department of Surgery, The University of Melbourne, Austin Health, Heidelberg, Victoria, Australia
    BMC Cancer 10:134. 2010
  9. pmc Bimodal role of Kupffer cells during colorectal cancer liver metastasis
    Shu Wen Wen
    Department of Surgery, The University of Melbourne, Austin Health, Heidelberg, Australia
    Cancer Biol Ther 14:606-13. 2013
  10. pmc Analysis of the platypus genome suggests a transposon origin for mammalian imprinting
    Andrew J Pask
    Department of Zoology, The University of Melbourne, Melbourne, Victoria, Australia
    Genome Biol 10:R1. 2009

Detail Information

Publications13

  1. pmc Expression and protein localisation of IGF2 in the marsupial placenta
    Eleanor I Ager
    Department of Zoology, The University of Melbourne, Melbourne, Victoria, 3010, Australia
    BMC Dev Biol 8:17. 2008
    ..This study examines the role of IGF2 in the yolk sac placenta of the tammar wallaby, Macropus eugenii...
  2. pmc Evolution of the CDKN1C-KCNQ1 imprinted domain
    Eleanor I Ager
    Department of Zoology, The University of Melbourne, Melbourne, Victoria, 3010, Australia
    BMC Evol Biol 8:163. 2008
    ..The CDKN1C and IGF2 genes are both imprinted and syntenic in the mouse and human, but in marsupials only IGF2 is imprinted. This study examines the evolution of features that, in eutherians, regulate CDKN1C imprinting...
  3. doi request reprint The renin-angiotensin system and malignancy
    Eleanor I Ager
    Department of Surgery, Austin Health, University of Melbourne, Heidelberg, Victoria 3084, Australia
    Carcinogenesis 29:1675-84. 2008
    ..Manipulation of the RAS may, therefore, provide a safe and inexpensive anticancer strategy...
  4. pmc Altered efficacy of AT1R-targeted treatment after spontaneous cancer cell-AT1R upregulation
    Eleanor I Ager
    The Department of Surgery, Austin Health, The University of Melbourne, Heidelberg, Vic, Australia
    BMC Cancer 11:274. 2011
    ..We aimed to establish if combined targeting of the 'classical' and 'alternative' arms of the RAS could result in synergistic inhibition of colorectal cancer (CRC) liver metastases...
  5. pmc Targeting the angiotensin II type 2 receptor (AT2R) in colorectal liver metastases
    Eleanor I Ager
    Department of Surgery, The University of Melbourne, Austin Health, Heidelberg, Victoria, Australia
    Cancer Cell Int 10:19. 2010
    ..This study examined the effect of AT2R activation with the agonist CGP42112A in a mouse model of CRC liver metastases...
  6. pmc The renin angiotensin system regulates Kupffer cells in colorectal liver metastases
    Shu Wen Wen
    Department of Surgery, The University of Melbourne, Austin Health, Heidelberg, Victoria, Australia
    Cancer Biol Ther 14:720-7. 2013
    ..The result of these studies suggests that manipulation of the RAS can alter KC numbers and may subsequently influence progression of CRC liver metastases...
  7. doi request reprint Genomic imprinting in marsupial placentation
    Marilyn B Renfree
    Department of Zoology, ARC Centre of Excellence for Kangaroo Genomics, The University of Melbourne, Melbourne, Victoria 3010, Australia
    Reproduction 136:523-31. 2008
    ..There is currently no evidence for genomic imprinting in the egg-laying monotreme mammals. However, since these mammals do have a short-lived placenta, imprinting appears to be correlated with viviparity but not placentation...
  8. pmc Changes in the renin angiotensin system during the development of colorectal cancer liver metastases
    Jaclyn H Neo
    Department of Surgery, The University of Melbourne, Austin Health, Heidelberg, Victoria, Australia
    BMC Cancer 10:134. 2010
    ..In this work we defined the expression of the various components of the RAS in both tumor and liver during the progression of this disease...
  9. pmc Bimodal role of Kupffer cells during colorectal cancer liver metastasis
    Shu Wen Wen
    Department of Surgery, The University of Melbourne, Austin Health, Heidelberg, Australia
    Cancer Biol Ther 14:606-13. 2013
    ..Taken together, our results indicate that the bimodal role of KC activity in liver tumors may provide the key to timing immunomodulatory intervention for the treatment of CRC liver metastases. ..
  10. pmc Analysis of the platypus genome suggests a transposon origin for mammalian imprinting
    Andrew J Pask
    Department of Zoology, The University of Melbourne, Melbourne, Victoria, Australia
    Genome Biol 10:R1. 2009
    ..The recent release of the platypus genome has provided the first opportunity to perform comparisons between prototherian (monotreme; which appear to lack imprinting) and therian (marsupial and eutherian; which have imprinting) mammals...
  11. doi request reprint Liver regeneration and tumour stimulation: implications of the renin-angiotensin system
    Shir Lin Koh
    Austin Health, Department of Surgery, The University of Melbourne, Heidelberg, Vic, Australia
    Liver Int 30:1414-26. 2010
    ..The potential of the RAS as a novel therapeutic target for CRC liver metastases patients undergoing liver resection will be outlined...
  12. ncbi request reprint The rod opsin pigments from two marsupial species, the South American bare-tailed woolly opossum and the Australian fat-tailed dunnart
    David M Hunt
    Division of Molecular Genetics, Institute of Ophthalmology, University College London, Bath Street, EC1V 9EL, London, UK
    Gene 323:157-62. 2003
    ..From microspectrophotometric measurements, the pigments in the two species show an 8 nm difference in peak absorbance; the molecular basis for this spectral shift is discussed and two candidate substitutions are identified...