C A Abbott

Summary

Affiliation: University of Sydney
Country: Australia

Publications

  1. ncbi Two highly conserved glutamic acid residues in the predicted beta propeller domain of dipeptidyl peptidase IV are required for its enzyme activity
    C A Abbott
    A W Morrow Gastroenterology and Liver Centre, Centenary Institute of Cell Biology and Cancer Medicine, Royal Prince Alfred Hospital and the University of Sydney, Newton, NSW, Australia
    FEBS Lett 458:278-84. 1999
  2. ncbi Cloning, expression and chromosomal localization of a novel human dipeptidyl peptidase (DPP) IV homolog, DPP8
    C A Abbott
    A W Morrow Gastroenterology and Liver Centre, Royal Prince Alfred Hospital, Centenary Institute of Cancer Medicine and Cell Biologyand The University of Sydney, NSW, Australia
    Eur J Biochem 267:6140-50. 2000
  3. ncbi Molecular pathogenesis of liver disease: an approach to hepatic inflammation, cirrhosis and liver transplant tolerance
    G W McCaughan
    Royal Prince Alfred Hospital, Centenary Institute of Cancer Medicine and Cell Biology and The University of Sydney, Australia
    Immunol Rev 174:172-91. 2000
  4. doi Soluble CD26 / dipeptidyl peptidase IV enhances human lymphocyte proliferation in vitro independent of dipeptidyl peptidase enzyme activity and adenosine deaminase binding
    D M T Yu
    A W Morrow Gastroenterology and Liver Centre, Royal Prince Alfred Hospital, Centenary Institute and Sydney Medical School, University of Sydney, Sydney, NSW, Australia
    Scand J Immunol 73:102-11. 2011
  5. ncbi Genomic organization, exact localization, and tissue expression of the human CD26 (dipeptidyl peptidase IV) gene
    C A Abbott
    A W Morrow Gastroenterology and Liver Centre, Royal Prince Alfred Hospital, Sydney, Australia
    Immunogenetics 40:331-8. 1994
  6. pmc Identification of novel molecules and pathogenic pathways in primary biliary cirrhosis: cDNA array analysis of intrahepatic differential gene expression
    N A Shackel
    AW Morrow Gastroenterology and Liver Centre, Centenary Institute of Cancer Medicine and Cell Biology, Royal Prince Alfred Hospital and the University of Sydney, Sydney, Australia
    Gut 49:565-76. 2001
  7. ncbi CD26
    T Chen
    School of Biological Sciences, Flinders University, Adelaide, South Australia, Australia
    J Biol Regul Homeost Agents 18:47-54. 2004

Collaborators

Detail Information

Publications7

  1. ncbi Two highly conserved glutamic acid residues in the predicted beta propeller domain of dipeptidyl peptidase IV are required for its enzyme activity
    C A Abbott
    A W Morrow Gastroenterology and Liver Centre, Centenary Institute of Cell Biology and Cancer Medicine, Royal Prince Alfred Hospital and the University of Sydney, Newton, NSW, Australia
    FEBS Lett 458:278-84. 1999
    ..This observation suggests a novel role in proteolysis for residues of DPP IV distant from the Ser-Asp-His catalytic triad...
  2. ncbi Cloning, expression and chromosomal localization of a novel human dipeptidyl peptidase (DPP) IV homolog, DPP8
    C A Abbott
    A W Morrow Gastroenterology and Liver Centre, Royal Prince Alfred Hospital, Centenary Institute of Cancer Medicine and Cell Biologyand The University of Sydney, NSW, Australia
    Eur J Biochem 267:6140-50. 2000
    ..The similarities between DPP8 and DPPIV in tissue expression pattern and substrates suggests a potential role for DPP8 in T-cell activation and immune function...
  3. ncbi Molecular pathogenesis of liver disease: an approach to hepatic inflammation, cirrhosis and liver transplant tolerance
    G W McCaughan
    Royal Prince Alfred Hospital, Centenary Institute of Cancer Medicine and Cell Biology and The University of Sydney, Australia
    Immunol Rev 174:172-91. 2000
    ..This review touches on these diverse aspects of liver function and disease...
  4. doi Soluble CD26 / dipeptidyl peptidase IV enhances human lymphocyte proliferation in vitro independent of dipeptidyl peptidase enzyme activity and adenosine deaminase binding
    D M T Yu
    A W Morrow Gastroenterology and Liver Centre, Royal Prince Alfred Hospital, Centenary Institute and Sydney Medical School, University of Sydney, Sydney, NSW, Australia
    Scand J Immunol 73:102-11. 2011
    ..Thus, effects of soluble human CD26 on human T-cell proliferation are mechanistically independent of both the enzyme activity and the ADA-binding capability of sCD26...
  5. ncbi Genomic organization, exact localization, and tissue expression of the human CD26 (dipeptidyl peptidase IV) gene
    C A Abbott
    A W Morrow Gastroenterology and Liver Centre, Royal Prince Alfred Hospital, Sydney, Australia
    Immunogenetics 40:331-8. 1994
    ..Only the 4.2 kb mRNA was expressed at low levels in skeletal muscle, heart, brain, and pancreas. Fluorescence in situ hybridization on metaphase chromosome spreads located the human CD26 gene to the long arm of chromosome 2(2q24.3)...
  6. pmc Identification of novel molecules and pathogenic pathways in primary biliary cirrhosis: cDNA array analysis of intrahepatic differential gene expression
    N A Shackel
    AW Morrow Gastroenterology and Liver Centre, Centenary Institute of Cancer Medicine and Cell Biology, Royal Prince Alfred Hospital and the University of Sydney, Sydney, Australia
    Gut 49:565-76. 2001
    ..CONCLUSION: Many genes implicated in intrahepatic inflammation, fibrosis, and regeneration were upregulated in PBC cirrhosis. In particular, increased expression of a number of Drosophila homologues was seen in PBC...
  7. ncbi CD26
    T Chen
    School of Biological Sciences, Flinders University, Adelaide, South Australia, Australia
    J Biol Regul Homeost Agents 18:47-54. 2004