Chris Tikellis

Summary

Country: Australia

Publications

  1. pmc The renoprotective actions of peroxisome proliferator-activated receptors agonists in diabetes
    M C Thomas
    Division of Diabetic Complications, Baker IDI Heart and Diabetes Institute, P O Box 6492, Melbourne, VIC 8008, Australia
    PPAR Res 2012:456529. 2012
  2. pmc Angiotensin-Converting Enzyme 2 (ACE2) Is a Key Modulator of the Renin Angiotensin System in Health and Disease
    Chris Tikellis
    Division of Diabetic Complications, Baker IDI Heart and Diabetes Institute, P O Box 6492 Melbourne, VIC 8008, Australia
    Int J Pept 2012:256294. 2012
  3. doi request reprint Angiotensin-converting enzyme 2 is a key modulator of the renin-angiotensin system in cardiovascular and renal disease
    Chris Tikellis
    Division of Diabetic Complications, Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, Australia
    Curr Opin Nephrol Hypertens 20:62-8. 2011
  4. doi request reprint Dicarbonyl stress in the absence of hyperglycemia increases endothelial inflammation and atherogenesis similar to that observed in diabetes
    Chris Tikellis
    Baker IDI Heart and Diabetes Institute, Melbourne, Australia Central Clinical School, Clinical Hematology, Monash University, Melbourne, Australia
    Diabetes 63:3915-25. 2014
  5. ncbi request reprint Direct antiatherosclerotic effects of PPAR agonists
    Karin A M Jandeleit-Dahm
    Diabetes Division, Albert Einstein JDRF Centre for Diabetes Complications, Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, Australia
    Curr Opin Lipidol 20:24-9. 2009
  6. doi request reprint Angiotensin-converting enzyme 2 mediates hyperfiltration associated with diabetes
    Chris Tikellis
    Baker IDI Heart and Diabetes Institute, PO Box 6492, St Kilda Central, Melbourne 8008, Victoria, Australia
    Am J Physiol Renal Physiol 306:F773-80. 2014
  7. doi request reprint Association of dietary sodium intake with atherogenesis in experimental diabetes and with cardiovascular disease in patients with Type 1 diabetes
    Chris Tikellis
    Baker IDI Heart and Diabetes Institute, PO Box 6492, Melbourne, Australia
    Clin Sci (Lond) 124:617-26. 2013
  8. pmc Short-Term Treatment with Diminazene Aceturate Ameliorates the Reduction in Kidney ACE2 Activity in Rats with Subtotal Nephrectomy
    Elena Velkoska
    Department of Medicine, The University of Melbourne, Austin Health, Heidelberg, Victoria, Australia
    PLoS ONE 10:e0118758. 2015
  9. doi request reprint Interaction of diabetes and ACE2 in the pathogenesis of cardiovascular disease in experimental diabetes
    Chris Tikellis
    Baker IDI Heart and Diabetes Institute, PO Box 6492, St Kilda Central, Melbourne 8008, Australia
    Clin Sci (Lond) 123:519-29. 2012

Detail Information

Publications9

  1. pmc The renoprotective actions of peroxisome proliferator-activated receptors agonists in diabetes
    M C Thomas
    Division of Diabetic Complications, Baker IDI Heart and Diabetes Institute, P O Box 6492, Melbourne, VIC 8008, Australia
    PPAR Res 2012:456529. 2012
    ..This review will examine these direct and indirect actions of PPAR agonists in the diabetic kidney and explore recent findings of clinical trials of PPAR agonists in patients with diabetes...
  2. pmc Angiotensin-Converting Enzyme 2 (ACE2) Is a Key Modulator of the Renin Angiotensin System in Health and Disease
    Chris Tikellis
    Division of Diabetic Complications, Baker IDI Heart and Diabetes Institute, P O Box 6492 Melbourne, VIC 8008, Australia
    Int J Pept 2012:256294. 2012
    ..Not surprisingly, current therapeutic strategies for ACE2 involve augmenting its expression using ACE2 adenoviruses, recombinant ACE2 or compounds in these diseases thereby affording some organ protection...
  3. doi request reprint Angiotensin-converting enzyme 2 is a key modulator of the renin-angiotensin system in cardiovascular and renal disease
    Chris Tikellis
    Division of Diabetic Complications, Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, Australia
    Curr Opin Nephrol Hypertens 20:62-8. 2011
    ..Angiotensin-converting enzyme 2 (ACE2) has recently emerged as a key regulator of the renin-angiotensin system in both health and disease...
  4. doi request reprint Dicarbonyl stress in the absence of hyperglycemia increases endothelial inflammation and atherogenesis similar to that observed in diabetes
    Chris Tikellis
    Baker IDI Heart and Diabetes Institute, Melbourne, Australia Central Clinical School, Clinical Hematology, Monash University, Melbourne, Australia
    Diabetes 63:3915-25. 2014
    ..Such data would suggest that a synergistic combination of RAGE antagonism and antioxidants may offer the greatest utility for the prevention and management of diabetic vascular complications. ..
  5. ncbi request reprint Direct antiatherosclerotic effects of PPAR agonists
    Karin A M Jandeleit-Dahm
    Diabetes Division, Albert Einstein JDRF Centre for Diabetes Complications, Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, Australia
    Curr Opin Lipidol 20:24-9. 2009
    ..The purpose of this review is to evaluate the currently available evidence for a direct vasculoprotective effect of PPAR agonists...
  6. doi request reprint Angiotensin-converting enzyme 2 mediates hyperfiltration associated with diabetes
    Chris Tikellis
    Baker IDI Heart and Diabetes Institute, PO Box 6492, St Kilda Central, Melbourne 8008, Victoria, Australia
    Am J Physiol Renal Physiol 306:F773-80. 2014
    ..The results of our study suggest that ACE2 plays a key role in the recruitment of the renal reserve and hyperfiltration associated with diabetes. ..
  7. doi request reprint Association of dietary sodium intake with atherogenesis in experimental diabetes and with cardiovascular disease in patients with Type 1 diabetes
    Chris Tikellis
    Baker IDI Heart and Diabetes Institute, PO Box 6492, Melbourne, Australia
    Clin Sci (Lond) 124:617-26. 2013
    ....
  8. pmc Short-Term Treatment with Diminazene Aceturate Ameliorates the Reduction in Kidney ACE2 Activity in Rats with Subtotal Nephrectomy
    Elena Velkoska
    Department of Medicine, The University of Melbourne, Austin Health, Heidelberg, Victoria, Australia
    PLoS ONE 10:e0118758. 2015
    ..In ex vivo studies, DIZE did not increase ACE2 activity in either Control or STNx kidney cortical membranes. It is not yet known if chronic administration of DIZE has long-term benefits to slow the progression of kidney disease. ..
  9. doi request reprint Interaction of diabetes and ACE2 in the pathogenesis of cardiovascular disease in experimental diabetes
    Chris Tikellis
    Baker IDI Heart and Diabetes Institute, PO Box 6492, St Kilda Central, Melbourne 8008, Australia
    Clin Sci (Lond) 123:519-29. 2012
    ....