Research Topics
| Sophia ZoungasSummaryAffiliation: The George Institute for International Health Country: Australia Publications
| Collaborators
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Detail Information
Publications
Severe hypoglycemia and risks of vascular events and deathSophia Zoungas
George Institute for International Health, University of Sydney, Sydney, Australia
N Engl J Med 363:1410-8. 2010..We analyzed data from a large study of intensive glucose lowering to explore the relationship between severe hypoglycemia and adverse clinical outcomes...
Combined effects of routine blood pressure lowering and intensive glucose control on macrovascular and microvascular outcomes in patients with type 2 diabetes: New results from the ADVANCE trialSophia Zoungas
The George Institute for International Health, University of Sydney, Sydney, New South Wales, Australia
Diabetes Care 32:2068-74. 2009..To assess the magnitude and independence of the effects of routine blood pressure lowering and intensive glucose control on clinical outcomes in patients with long-standing type 2 diabetes...
Systematic review: sodium bicarbonate treatment regimens for the prevention of contrast-induced nephropathySophia Zoungas
University of Sydney, Sydney, Australia
Ann Intern Med 151:631-8. 2009..Intravenous sodium bicarbonate has been proposed to reduce the risk for contrast-induced nephropathy (CIN)...
Cardiovascular outcomes in type 2 diabetes: the impact of preventative therapiesSophia Zoungas
Diabetes Research Program, Cardiovascular Division, The George Institute for International Health, University of Sydney, Missenden Road, NSW 2050, Australia
Ann N Y Acad Sci 1212:29-40. 2010..The role of antiplatelet agents remains unknown, as adequately powered trials of aspirin for the primary prevention of cardiovascular events in patients with diabetes have not yet been completed...
Efficacy and safety of routine blood pressure lowering in older patients with diabetes: results from the ADVANCE trialToshiharu Ninomiya
The George Institute for International Health, University of Sydney, New South Wales, Australia
J Hypertens 28:1141-9. 2010....
Contemporary model for cardiovascular risk prediction in people with type 2 diabetesAndre Pascal Kengne
The George Institute for International Health, The University of Sydney, Australia
Eur J Cardiovasc Prev Rehabil 18:393-8. 2011..This report presents a contemporary model for predicting cardiovascular risk in people with type 2 diabetes mellitus...
Effects of blood pressure lowering on cardiovascular outcomes in different cardiovascular risk groups among participants with type 2 diabetesSusan van Dieren
The George Institute for Global Health, University of Sydney, Sydney, Australia
Diabetes Res Clin Pract 98:83-90. 2012..To asses differences in treatment effects of a fixed combination of perindopril-indapamide on major clinical outcomes in patients with type 2 diabetes across subgroups of cardiovascular risk...
Prediction of kidney-related outcomes in patients with type 2 diabetesMeg J Jardine
George Institute For Global Health, Sydney, Australia
Am J Kidney Dis 60:770-8. 2012..Tools are needed to predict which individuals with diabetes will develop kidney disease and its complications...
Effects of a fixed combination of perindopril and indapamide in patients with type 2 diabetes and chronic kidney diseaseHiddo J Lambers Heerspink
The George Institute for International Health, University of Sydney, Missenden Road, Camperdown, Sydney, NSW 2050, Australia
Eur Heart J 31:2888-96. 2010..In these analyses of the ADVANCE trial, we assessed the effects of a fixed combination of perindopril-indapamide on renal and cardiovascular outcomes in patients with type 2 diabetes according to baseline CKD stage...
Blood pressure variables and cardiovascular risk: new findings from ADVANCEAndre Pascal Kengne
ADVANCE Collaborative Group, The George Institute for International Health, PO Box M201, Missenden Road, Sydney NSW 2050, Australia
Hypertension 54:399-404. 2009..However, SBP may be the simplest and most useful predictor across a wider range of age groups and populations...
Does glycemic control offer similar benefits among patients with diabetes in different regions of the world? Results from the ADVANCE trialMark Woodward
The George Institute, University of Sydney, Sydney, Australia
Diabetes Care 34:2491-5. 2011..We examined whether the effects of intensive glycemic control on major outcomes in ADVANCE differ between participants from Asia, established market economies (EMEs), and eastern Europe...
Comparison of waist-to-hip ratio and other obesity indices as predictors of cardiovascular disease risk in people with type-2 diabetes: a prospective cohort study from ADVANCESebastien Czernichow
The George Institute for International Health, The University of Sydney, New South Wales, Australia
Eur J Cardiovasc Prev Rehabil 18:312-9. 2011....
Aspirin is beneficial in hypertensive patients with chronic kidney disease: a post-hoc subgroup analysis of a randomized controlled trialMeg J Jardine
The George Institute for Global Health, Sydney, Australia Concord Repatriation General Hospital, Sydney, Australia
J Am Coll Cardiol 56:956-65. 2010..The purpose of this study was to determine the benefit and risk associated with antiplatelet therapy in the chronic kidney disease (CKD) population...
Albuminuria and kidney function independently predict cardiovascular and renal outcomes in diabetesToshiharu Ninomiya
George Institute for International Health, University of Sydney, Sydney, NSW, Australia
J Am Soc Nephrol 20:1813-21. 2009..In conclusion, high albuminuria and low eGFR are independent risk factors for cardiovascular and renal events among patients with type 2 diabetes...
Effect of lowering blood pressure on cardiovascular events and mortality in patients on dialysis: a systematic review and meta-analysis of randomised controlled trialsHiddo J Lambers Heerspink
George Institute for International Health, University of Sydney, Sydney, Australia
Lancet 373:1009-15. 2009..We did a systematic review and meta-analysis to assess the effect of blood pressure lowering in patients on dialysis...
Intensive glucose control improves kidney outcomes in patients with type 2 diabetesVlado Perkovic
The George Institute for Global Health, University of Sydney, Sydney, New South Wales, Australia
Kidney Int 83:517-23. 2013..Thus, improved glucose control will improve major kidney outcomes in patients with type 2 diabetes...
The risk of cancer in people with diabetes and chronic kidney diseaseGermaine Wong
Centre for Kidney Research and Kids Research Institute, The Children s Hospital at Westmead, Sydney, Australia
Nephrol Dial Transplant 27:3337-44. 2012....
The effect of folic acid based homocysteine lowering on cardiovascular events in people with kidney disease: systematic review and meta-analysisMeg J Jardine
George Institute For Global Health, PO Box M201, Camperdown, NSW 2050, Australia
BMJ 344:e3533. 2012..To systematically review the effect of folic acid based homocysteine lowering on cardiovascular outcomes in people with kidney disease...
Resting heart rate and the risk of microvascular complications in patients with type 2 diabetes mellitusGraham S Hillis
The George Institute for Global Health, University of Sydney, Australia
J Am Heart Assoc 1:e002832. 2012..The present study tests the hypothesis that a higher resting heart rate is associated with an increased incidence and a greater progression of microvascular complications in patients with type 2 diabetes mellitus...
Low HDL cholesterol and the risk of diabetic nephropathy and retinopathy: results of the ADVANCE studyJamie Morton
The Heart Research Institute, Sydney, New South Wales, Australia
Diabetes Care 35:2201-6. 2012..We tested the association between HDL-C and microvascular disease in a cohort of patients with type 2 diabetes...
Effects of the endpoint adjudication process on the results of a randomised controlled trial: the ADVANCE trialJun Hata
The George Institute for Global Health, University of Sydney, Sydney, New South Wales, Australia
PLoS ONE 8:e55807. 2013..The aim of the present analysis is to assess the effects of the endpoint adjudication process on the main findings of the ADVANCE trial (Trial registration: ClinicalTrials.gov NCT00145925)...
Diabetes. Insights from the extended follow-up of the ACCORD trialSophia Zoungas
The George Institute for Global Health, University of Sydney, Missenden Road, Camperdown, NSW 2050, Sydney, Australia
Nat Rev Cardiol 8:308-10. 2011..These data add to existing knowledge on the benefits of glycemic control in this patient population...
Comparison of near-patient capillary glucose measurement and a risk assessment questionnaire in screening for type 2 diabetes in a high-risk population in rural IndiaGeorgia E Ritchie
The George Institute for Global Health, University of Sydney, Sydney, New South Wales, Australia
Diabetes Care 34:44-9. 2011..To assess the utility of a point-of-care (POC) capillary blood glucose measurement as compared with routine clinical parameters in predicting undiagnosed diabetes in a low-resource rural India setting...
Cardiovascular risk management in chronic kidney disease in general practice (the AusHEART study)Mona Razavian
The George Institute for Global Health, Sydney, Australia
Nephrol Dial Transplant 27:1396-402. 2012..The objectives of this study were to assess the prevalence, general practitioner (GP) awareness and extent of current evidence-practice gaps in the management of CKD in Australian primary care...
How to read a report of a randomized controlled trialMin Jun
The George Institute for International Health, The University of Sydney, PO Box 201, Missenden Road, Sydney, NSW 2050, Australia
Nephrology (Carlton) 15:153-7. 2010..This paper aims to explain how to approach critical appraisal, by highlighting and illustrating important questions that help determine the reliability of results from randomized trials...
