Sophia Zoungas

Summary

Affiliation: The George Institute for International Health
Country: Australia

Publications

  1. doi request reprint Severe hypoglycemia and risks of vascular events and death
    Sophia Zoungas
    George Institute for International Health, University of Sydney, Sydney, Australia
    N Engl J Med 363:1410-8. 2010
  2. ncbi request reprint Cardiovascular outcomes in type 2 diabetes: the impact of preventative therapies
    Sophia Zoungas
    Diabetes Research Program, Cardiovascular Division, The George Institute for International Health, University of Sydney, Missenden Road, NSW 2050, Australia
    Ann N Y Acad Sci 1212:29-40. 2010
  3. ncbi request reprint Systematic review: sodium bicarbonate treatment regimens for the prevention of contrast-induced nephropathy
    Sophia Zoungas
    University of Sydney, Sydney, Australia
    Ann Intern Med 151:631-8. 2009
  4. pmc Combined effects of routine blood pressure lowering and intensive glucose control on macrovascular and microvascular outcomes in patients with type 2 diabetes: New results from the ADVANCE trial
    Sophia Zoungas
    The George Institute for International Health, University of Sydney, Sydney, New South Wales, Australia
    Diabetes Care 32:2068-74. 2009
  5. doi request reprint Effects of combination of perindopril, indapamide, and calcium channel blockers in patients with type 2 diabetes mellitus: results from the Action In Diabetes and Vascular Disease: Preterax and Diamicron Controlled Evaluation (ADVANCE) trial
    John Chalmers
    The George Institute for Global Health, PO Box M201, Camperdown, NSW 2050, Australia
    Hypertension 63:259-64. 2014
  6. ncbi request reprint Efficacy and safety of routine blood pressure lowering in older patients with diabetes: results from the ADVANCE trial
    Toshiharu Ninomiya
    The George Institute for International Health, University of Sydney, New South Wales, Australia
    J Hypertens 28:1141-9. 2010
  7. ncbi request reprint Effects of visit-to-visit variability in systolic blood pressure on macrovascular and microvascular complications in patients with type 2 diabetes mellitus: the ADVANCE trial
    Jun Hata
    From The George Institute for Global Health, University of Sydney, Sydney, Australia J H, H A, M W, S Z, C A, A P, B N, S M, J C University of Oxford, Oxford, United Kingdom P M R, S M School of Public Health, Monash University, Clayton, Australia S Z Bond University, Gold Coast, Australia P G Université de Montréal, Montreal, Canada P H University of Milan Bicocca, Milan, Italy G M Imperial College, London, United Kingdom N P and University College London UCL and the National Institute for Health Research UCL Hospitals Biomedical Research Centre, London, United Kingdom B W
    Circulation 128:1325-34. 2013
  8. doi request reprint Contemporary model for cardiovascular risk prediction in people with type 2 diabetes
    Andre Pascal Kengne
    The George Institute for International Health, The University of Sydney, Australia
    Eur J Cardiovasc Prev Rehabil 18:393-8. 2011
  9. ncbi request reprint The association of high-density lipoprotein cholesterol with cancer incidence in type II diabetes: a case of reverse causality?
    Jamie Morton
    The Heart Research Institute, Newtown Sydney Medical School, University of Sydney, Camperdown, Sydney, New South Wales, Australia
    Cancer Epidemiol Biomarkers Prev 22:1628-33. 2013
  10. ncbi request reprint Intensive glucose control improves kidney outcomes in patients with type 2 diabetes
    Vlado Perkovic
    The George Institute for Global Health, University of Sydney, Sydney, New South Wales, Australia
    Kidney Int 83:517-23. 2013

Detail Information

Publications29

  1. doi request reprint Severe hypoglycemia and risks of vascular events and death
    Sophia Zoungas
    George Institute for International Health, University of Sydney, Sydney, Australia
    N Engl J Med 363:1410-8. 2010
    ..We analyzed data from a large study of intensive glucose lowering to explore the relationship between severe hypoglycemia and adverse clinical outcomes...
  2. ncbi request reprint Cardiovascular outcomes in type 2 diabetes: the impact of preventative therapies
    Sophia Zoungas
    Diabetes Research Program, Cardiovascular Division, The George Institute for International Health, University of Sydney, Missenden Road, NSW 2050, Australia
    Ann N Y Acad Sci 1212:29-40. 2010
    ..The role of antiplatelet agents remains unknown, as adequately powered trials of aspirin for the primary prevention of cardiovascular events in patients with diabetes have not yet been completed...
  3. ncbi request reprint Systematic review: sodium bicarbonate treatment regimens for the prevention of contrast-induced nephropathy
    Sophia Zoungas
    University of Sydney, Sydney, Australia
    Ann Intern Med 151:631-8. 2009
    ..Intravenous sodium bicarbonate has been proposed to reduce the risk for contrast-induced nephropathy (CIN)...
  4. pmc Combined effects of routine blood pressure lowering and intensive glucose control on macrovascular and microvascular outcomes in patients with type 2 diabetes: New results from the ADVANCE trial
    Sophia Zoungas
    The George Institute for International Health, University of Sydney, Sydney, New South Wales, Australia
    Diabetes Care 32:2068-74. 2009
    ..To assess the magnitude and independence of the effects of routine blood pressure lowering and intensive glucose control on clinical outcomes in patients with long-standing type 2 diabetes...
  5. doi request reprint Effects of combination of perindopril, indapamide, and calcium channel blockers in patients with type 2 diabetes mellitus: results from the Action In Diabetes and Vascular Disease: Preterax and Diamicron Controlled Evaluation (ADVANCE) trial
    John Chalmers
    The George Institute for Global Health, PO Box M201, Camperdown, NSW 2050, Australia
    Hypertension 63:259-64. 2014
    ..38). There was no detectable increase in adverse effects in those receiving CCB. The combination of perindopril and indapamide with CCBs seems to provide further protection against mortality in patients with type 2 diabetes mellitus. ..
  6. ncbi request reprint Efficacy and safety of routine blood pressure lowering in older patients with diabetes: results from the ADVANCE trial
    Toshiharu Ninomiya
    The George Institute for International Health, University of Sydney, New South Wales, Australia
    J Hypertens 28:1141-9. 2010
    ....
  7. ncbi request reprint Effects of visit-to-visit variability in systolic blood pressure on macrovascular and microvascular complications in patients with type 2 diabetes mellitus: the ADVANCE trial
    Jun Hata
    From The George Institute for Global Health, University of Sydney, Sydney, Australia J H, H A, M W, S Z, C A, A P, B N, S M, J C University of Oxford, Oxford, United Kingdom P M R, S M School of Public Health, Monash University, Clayton, Australia S Z Bond University, Gold Coast, Australia P G Université de Montréal, Montreal, Canada P H University of Milan Bicocca, Milan, Italy G M Imperial College, London, United Kingdom N P and University College London UCL and the National Institute for Health Research UCL Hospitals Biomedical Research Centre, London, United Kingdom B W
    Circulation 128:1325-34. 2013
    ..However, it remains uncertain whether these parameters predict the risks of macrovascular and microvascular complications in patients with type 2 diabetes mellitus...
  8. doi request reprint Contemporary model for cardiovascular risk prediction in people with type 2 diabetes
    Andre Pascal Kengne
    The George Institute for International Health, The University of Sydney, Australia
    Eur J Cardiovasc Prev Rehabil 18:393-8. 2011
    ..This report presents a contemporary model for predicting cardiovascular risk in people with type 2 diabetes mellitus...
  9. ncbi request reprint The association of high-density lipoprotein cholesterol with cancer incidence in type II diabetes: a case of reverse causality?
    Jamie Morton
    The Heart Research Institute, Newtown Sydney Medical School, University of Sydney, Camperdown, Sydney, New South Wales, Australia
    Cancer Epidemiol Biomarkers Prev 22:1628-33. 2013
    ..Patients with type II diabetes typically have low HDL-C; however, the association between HDL-C and cancer has not been examined in this population...
  10. ncbi request reprint Intensive glucose control improves kidney outcomes in patients with type 2 diabetes
    Vlado Perkovic
    The George Institute for Global Health, University of Sydney, Sydney, New South Wales, Australia
    Kidney Int 83:517-23. 2013
    ..Thus, improved glucose control will improve major kidney outcomes in patients with type 2 diabetes...
  11. pmc Effects of the endpoint adjudication process on the results of a randomised controlled trial: the ADVANCE trial
    Jun Hata
    The George Institute for Global Health, University of Sydney, Sydney, New South Wales, Australia
    PLoS ONE 8:e55807. 2013
    ..The aim of the present analysis is to assess the effects of the endpoint adjudication process on the main findings of the ADVANCE trial (Trial registration: ClinicalTrials.gov NCT00145925)...
  12. doi request reprint Effects of blood pressure lowering on cardiovascular outcomes in different cardiovascular risk groups among participants with type 2 diabetes
    Susan van Dieren
    The George Institute for Global Health, University of Sydney, Sydney, Australia
    Diabetes Res Clin Pract 98:83-90. 2012
    ..To asses differences in treatment effects of a fixed combination of perindopril-indapamide on major clinical outcomes in patients with type 2 diabetes across subgroups of cardiovascular risk...
  13. doi request reprint Prediction of kidney-related outcomes in patients with type 2 diabetes
    Meg J Jardine
    George Institute For Global Health, Sydney, Australia
    Am J Kidney Dis 60:770-8. 2012
    ..Tools are needed to predict which individuals with diabetes will develop kidney disease and its complications...
  14. doi request reprint Effects of a fixed combination of perindopril and indapamide in patients with type 2 diabetes and chronic kidney disease
    Hiddo J Lambers Heerspink
    The George Institute for International Health, University of Sydney, Missenden Road, Camperdown, Sydney, NSW 2050, Australia
    Eur Heart J 31:2888-96. 2010
    ..In these analyses of the ADVANCE trial, we assessed the effects of a fixed combination of perindopril-indapamide on renal and cardiovascular outcomes in patients with type 2 diabetes according to baseline CKD stage...
  15. ncbi request reprint Blood pressure variables and cardiovascular risk: new findings from ADVANCE
    Andre Pascal Kengne
    ADVANCE Collaborative Group, The George Institute for International Health, PO Box M201, Missenden Road, Sydney NSW 2050, Australia
    Hypertension 54:399-404. 2009
    ..However, SBP may be the simplest and most useful predictor across a wider range of age groups and populations...
  16. pmc Resting heart rate and the risk of microvascular complications in patients with type 2 diabetes mellitus
    Graham S Hillis
    The George Institute for Global Health, University of Sydney, Australia
    J Am Heart Assoc 1:e002832. 2012
    ..The present study tests the hypothesis that a higher resting heart rate is associated with an increased incidence and a greater progression of microvascular complications in patients with type 2 diabetes mellitus...
  17. pmc Does glycemic control offer similar benefits among patients with diabetes in different regions of the world? Results from the ADVANCE trial
    Mark Woodward
    The George Institute, University of Sydney, Sydney, Australia
    Diabetes Care 34:2491-5. 2011
    ..We examined whether the effects of intensive glycemic control on major outcomes in ADVANCE differ between participants from Asia, established market economies (EMEs), and eastern Europe...
  18. ncbi request reprint Aspirin is beneficial in hypertensive patients with chronic kidney disease: a post-hoc subgroup analysis of a randomized controlled trial
    Meg J Jardine
    The George Institute for Global Health, Sydney, Australia Concord Repatriation General Hospital, Sydney, Australia
    J Am Coll Cardiol 56:956-65. 2010
    ..The purpose of this study was to determine the benefit and risk associated with antiplatelet therapy in the chronic kidney disease (CKD) population...
  19. doi request reprint Comparison of waist-to-hip ratio and other obesity indices as predictors of cardiovascular disease risk in people with type-2 diabetes: a prospective cohort study from ADVANCE
    Sebastien Czernichow
    The George Institute for International Health, The University of Sydney, New South Wales, Australia
    Eur J Cardiovasc Prev Rehabil 18:312-9. 2011
    ....
  20. ncbi request reprint Impact of Visit-to-Visit Glycemic Variability on the Risks of Macrovascular and Microvascular Events and All-Cause Mortality in Type 2 Diabetes: The ADVANCE Trial
    Yoichiro Hirakawa
    The George Institute for Global Health, University of Sydney, Sydney, Australia
    Diabetes Care 37:2359-65. 2014
    ..Therefore, we assessed the effects of visit-to-visit variability (VVV) in HbA1c and fasting glucose on major outcomes in the ADVANCE (Action in Diabetes and Vascular Disease: Preterax and Diamicron MR Controlled Evaluation) trial...
  21. pmc Effect of lowering blood pressure on cardiovascular events and mortality in patients on dialysis: a systematic review and meta-analysis of randomised controlled trials
    Hiddo J Lambers Heerspink
    George Institute for International Health, University of Sydney, Sydney, Australia
    Lancet 373:1009-15. 2009
    ..We did a systematic review and meta-analysis to assess the effect of blood pressure lowering in patients on dialysis...
  22. pmc Albuminuria and kidney function independently predict cardiovascular and renal outcomes in diabetes
    Toshiharu Ninomiya
    George Institute for International Health, University of Sydney, Sydney, NSW, Australia
    J Am Soc Nephrol 20:1813-21. 2009
    ..In conclusion, high albuminuria and low eGFR are independent risk factors for cardiovascular and renal events among patients with type 2 diabetes...
  23. pmc Low HDL cholesterol and the risk of diabetic nephropathy and retinopathy: results of the ADVANCE study
    Jamie Morton
    The Heart Research Institute, Sydney, New South Wales, Australia
    Diabetes Care 35:2201-6. 2012
    ..We tested the association between HDL-C and microvascular disease in a cohort of patients with type 2 diabetes...
  24. ncbi request reprint The risk of cancer in people with diabetes and chronic kidney disease
    Germaine Wong
    Centre for Kidney Research and Kids Research Institute, The Children s Hospital at Westmead, Sydney, Australia
    Nephrol Dial Transplant 27:3337-44. 2012
    ..The aim of our study was to determine the association of CKD [defined as an estimated glomerular filtration rate (eGFR) < 60 mL/min] with the overall and site-specific risks of incident cancers among individuals with Type 2 diabetes...
  25. pmc The effect of folic acid based homocysteine lowering on cardiovascular events in people with kidney disease: systematic review and meta-analysis
    Meg J Jardine
    George Institute For Global Health, PO Box M201, Camperdown, NSW 2050, Australia
    BMJ 344:e3533. 2012
    ..To systematically review the effect of folic acid based homocysteine lowering on cardiovascular outcomes in people with kidney disease...
  26. pmc Comparison of near-patient capillary glucose measurement and a risk assessment questionnaire in screening for type 2 diabetes in a high-risk population in rural India
    Georgia E Ritchie
    The George Institute for Global Health, University of Sydney, Sydney, New South Wales, Australia
    Diabetes Care 34:44-9. 2011
    ..To assess the utility of a point-of-care (POC) capillary blood glucose measurement as compared with routine clinical parameters in predicting undiagnosed diabetes in a low-resource rural India setting...
  27. doi request reprint Diabetes. Insights from the extended follow-up of the ACCORD trial
    Sophia Zoungas
    The George Institute for Global Health, University of Sydney, Missenden Road, Camperdown, NSW 2050, Sydney, Australia
    Nat Rev Cardiol 8:308-10. 2011
    ..These data add to existing knowledge on the benefits of glycemic control in this patient population...
  28. doi request reprint Cardiovascular risk management in chronic kidney disease in general practice (the AusHEART study)
    Mona Razavian
    The George Institute for Global Health, Sydney, Australia
    Nephrol Dial Transplant 27:1396-402. 2012
    ..The objectives of this study were to assess the prevalence, general practitioner (GP) awareness and extent of current evidence-practice gaps in the management of CKD in Australian primary care...
  29. ncbi request reprint How to read a report of a randomized controlled trial
    Min Jun
    The George Institute for International Health, The University of Sydney, PO Box 201, Missenden Road, Sydney, NSW 2050, Australia
    Nephrology (Carlton) 15:153-7. 2010
    ..This paper aims to explain how to approach critical appraisal, by highlighting and illustrating important questions that help determine the reliability of results from randomized trials...