Anne M Verhagen

Summary

Affiliation: The Walter and Eliza Hall Institute of Medical Research
Country: Australia

Publications

  1. ncbi TNF and CD95 promote IL-8 gene transactivation via independent elements in colon carcinoma cells
    A M Verhagen
    The Walter and Eliza Hall Institute of Medical Research, Post Office Royal Melbourne Hospital, Victoria 3050, Australia
    Cytokine 15:108-12. 2001
  2. ncbi Inhibitor of apoptosis proteins and their relatives: IAPs and other BIRPs
    A M Verhagen
    The Walter and Eliza Hall Institute of Medical Research, Post Office, Royal Melbourne Hospital, Victoria 3050, Australia
    Genome Biol 2:REVIEWS3009. 2001
  3. ncbi HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins
    Anne M Verhagen
    Walter and Eliza Hall Institute of Medical Research, Post Office Royal Melbourne Hospital, Victoria 3050, Australia
    J Biol Chem 277:445-54. 2002
  4. ncbi Cell death regulation by the mammalian IAP antagonist Diablo/Smac
    A M Verhagen
    The Walter and Eliza Hall Institute of Medical Research, Post Office Royal Melbourne Hospital, Victoria 3050, Australia
    Apoptosis 7:163-6. 2002
  5. ncbi Revealing the intricacies of cancer
    Anne M Verhagen
    The Walter and Eliza Hall Institute of Medical Research, Post Office Royal Melbourne Hospital, Victoria 3050, Australia
    Genome Biol 3:REPORTS4015. 2002
  6. ncbi The anti-apoptotic activity of XIAP is retained upon mutation of both the caspase 3- and caspase 9-interacting sites
    John Silke
    The Walter and Eliza Hall Institute of Medical Research, Victoria 3050, Australia
    J Cell Biol 157:115-24. 2002
  7. ncbi Nck adaptor proteins link Tks5 to invadopodia actin regulation and ECM degradation
    Stanley S Stylli
    Department of Surgery, University of Melbourne, Level 5, Clinical Sciences Building, Royal Melbourne Hospital, Parkville, Victoria 3052, Australia
    J Cell Sci 122:2727-40. 2009
  8. ncbi Dok-related protein negatively regulates T cell development via its RasGTPase-activating protein and Nck docking sites
    Raffi Gugasyan
    Walter and Eliza Hall Institute of Medical Research, University of Melbourne, Parkville 3050, Australia
    J Cell Biol 158:115-25. 2002
  9. ncbi Association of mammalian sterile twenty kinases, Mst1 and Mst2, with hSalvador via C-terminal coiled-coil domains, leads to its stabilization and phosphorylation
    Bernard A Callus
    The Walter and Eliza Hall Institute, Parkville, VC, Australia
    FEBS J 273:4264-76. 2006

Collaborators

Detail Information

Publications9

  1. ncbi TNF and CD95 promote IL-8 gene transactivation via independent elements in colon carcinoma cells
    A M Verhagen
    The Walter and Eliza Hall Institute of Medical Research, Post Office Royal Melbourne Hospital, Victoria 3050, Australia
    Cytokine 15:108-12. 2001
    ..These results suggest that promoter elements/enhancers involved in CD95 mediated IL-8 induction are distinct from those used by TNF and not contained within the 1.6 kb region immediately upstream of the initiation codon...
  2. ncbi Inhibitor of apoptosis proteins and their relatives: IAPs and other BIRPs
    A M Verhagen
    The Walter and Eliza Hall Institute of Medical Research, Post Office, Royal Melbourne Hospital, Victoria 3050, Australia
    Genome Biol 2:REVIEWS3009. 2001
    ..These Survivin-like BIRPs regulate cytokinesis and mitotic spindle formation. In this review, we describe the IAPs and other BIRPs, their evolutionary relationships and their subcellular and tissue localizations...
  3. ncbi HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins
    Anne M Verhagen
    Walter and Eliza Hall Institute of Medical Research, Post Office Royal Melbourne Hospital, Victoria 3050, Australia
    J Biol Chem 277:445-54. 2002
    ....
  4. ncbi Cell death regulation by the mammalian IAP antagonist Diablo/Smac
    A M Verhagen
    The Walter and Eliza Hall Institute of Medical Research, Post Office Royal Melbourne Hospital, Victoria 3050, Australia
    Apoptosis 7:163-6. 2002
    ..Since its discovery, there have been numerous studies investigating how Diablo/Smac interacts with IAPs and promotes cell death. Here we review what is currently known about Diablo/Smac and speculate on other mammalian IAP antagonists...
  5. ncbi Revealing the intricacies of cancer
    Anne M Verhagen
    The Walter and Eliza Hall Institute of Medical Research, Post Office Royal Melbourne Hospital, Victoria 3050, Australia
    Genome Biol 3:REPORTS4015. 2002
  6. ncbi The anti-apoptotic activity of XIAP is retained upon mutation of both the caspase 3- and caspase 9-interacting sites
    John Silke
    The Walter and Eliza Hall Institute of Medical Research, Victoria 3050, Australia
    J Cell Biol 157:115-24. 2002
    ....
  7. ncbi Nck adaptor proteins link Tks5 to invadopodia actin regulation and ECM degradation
    Stanley S Stylli
    Department of Surgery, University of Melbourne, Level 5, Clinical Sciences Building, Royal Melbourne Hospital, Parkville, Victoria 3052, Australia
    J Cell Sci 122:2727-40. 2009
    ..These results identify a Src-Tks5-Nck pathway in ECM-degrading invadopodia that shows parallels with pathways linking several mammalian and pathogen-derived proteins to local actin regulation...
  8. ncbi Dok-related protein negatively regulates T cell development via its RasGTPase-activating protein and Nck docking sites
    Raffi Gugasyan
    Walter and Eliza Hall Institute of Medical Research, University of Melbourne, Parkville 3050, Australia
    J Cell Biol 158:115-25. 2002
    ..In contrast, a minimal effect on B cell and myeloid lineage development was observed. Importantly, functional RasGAP and Nck binding sites were found to be essential for the biological effects of DokR in vitro and in vivo...
  9. ncbi Association of mammalian sterile twenty kinases, Mst1 and Mst2, with hSalvador via C-terminal coiled-coil domains, leads to its stabilization and phosphorylation
    Bernard A Callus
    The Walter and Eliza Hall Institute, Parkville, VC, Australia
    FEBS J 273:4264-76. 2006
    ..Together these results show that hSav can bind to, and be phosphorylated by, Mst, and that the stabilizing effect of Mst on hSav requires its interaction with hSav but is probably not due to phosphorylation of hSav by Mst...