Justin Tan

Summary

Affiliation: The Bionic Ear Institute
Country: Australia

Publications

  1. ncbi Carbon nanotubes: biocompatibility of immobilized aligned carbon nanotubes (small 8/2011)
    David A X Nayagam
    The Bionic Ear Institute, 384 388 Albert Street, East Melbourne, 3002, Australia
    Small 7:981. 2011
  2. ncbi Aminoglycoside-induced degeneration of adult spiral ganglion neurons involves differential modulation of tyrosine kinase B and p75 neurotrophin receptor signaling
    Justin Tan
    Department of Otolaryngology, 32 Gisborne St, East Melbourne, Victoria 3002, Australia
    Am J Pathol 169:528-43. 2006
  3. ncbi Cochlear implants stimulate activity-dependent CREB pathway in the deaf auditory cortex: implications for molecular plasticity induced by neural prosthetic devices
    Justin Tan
    The Bionic Ear Institute, East Melbourne, Victoria 3002, Australia
    Cereb Cortex 18:1799-813. 2008
  4. ncbi The p75 neurotrophin receptor protects primary auditory neurons against acoustic trauma in mice
    Justin Tan
    The Bionic Ear Institute, 384 388 Albert St, East Melbourne, Victoria 3002, Australia
    Hear Res 268:46-59. 2010
  5. ncbi Biocompatibility of immobilized aligned carbon nanotubes
    David A X Nayagam
    The Bionic Ear Institute, 384 388 Albert Street, East Melbourne, 3002, Australia
    Small 7:1035-42. 2011
  6. ncbi Nanoporous peptide particles for encapsulating and releasing neurotrophic factors in an animal model of neurodegeneration
    Justin Tan
    Bionics Institute, East Melbourne, Victoria 3002, Australia
    Adv Mater 24:3362-6. 2012
  7. ncbi Thyroxine treatments do not correct inner ear defects in tmprss1 mutant mice
    Syazana Hanifa
    The Bionic Ear Institute, University of Melbourne, East Melbourne, Victoria, Australia
    Neuroreport 21:897-901. 2010
  8. ncbi Lack of Bdnf and TrkB signalling in the postnatal cochlea leads to a spatial reshaping of innervation along the tonotopic axis and hearing loss
    Thomas Schimmang
    Center for Molecular Neurobiology Hamburg, University of Hamburg, Falkenreid, Hamburg, Germany
    Development 130:4741-50. 2003
  9. ncbi BDNF mRNA expression and protein localization are changed in age-related hearing loss
    Lukas Ruttiger
    Molecular Neurobiology, Tübingen Hearing Research Center, Department of Otorhinolaryngology, University of Tubingen, Tubingen, Germany
    Neurobiol Aging 28:586-601. 2007
  10. ncbi Midazolam reverses salicylate-induced changes in brain-derived neurotrophic factor and arg3.1 expression: implications for tinnitus perception and auditory plasticity
    Rama Panford-Walsh
    Department of Otorhinolaryngology, Universitat Tubingen, Tubingen, Germany
    Mol Pharmacol 74:595-604. 2008

Collaborators

  • Robert K Shepherd
  • Jun Chen
  • Graeme M Clark
  • Jin Xu
  • David A X Nayagam
  • Marlies Knipper
  • Thomas Schimmang
  • Rama Panford-Walsh
  • Lukas Ruttiger
  • Ulrike Zimmermann
  • Karin Rohbock
  • Iris Köpschall
  • Chris E Williams
  • Gordon G Wallace
  • Peter Innis
  • Richard A Williams
  • Sue Finch
  • Kylie A Magee
  • Jennifer Irwin
  • Ronald T Leung
  • Syazana Hanifa
  • Annette Limberger
  • Marcus Müller
  • Estela Carnicero
  • Hamish S Scott
  • Pauline Crewther
  • Michel Guipponi
  • Hyun-Soon Geisler
  • Elmar Oestreicher
  • Wibke Singer
  • Saida Hadjab
  • Anna Vieljans
  • Hyun Soon Geisler
  • Jelka Cimerman
  • Jürgen Theodor Fraenzer
  • Rama Panford Walsh
  • Liliana Minichiello
  • Maria Teresa Alonso

Detail Information

Publications11

  1. ncbi Carbon nanotubes: biocompatibility of immobilized aligned carbon nanotubes (small 8/2011)
    David A X Nayagam
    The Bionic Ear Institute, 384 388 Albert Street, East Melbourne, 3002, Australia
    Small 7:981. 2011
    ..Collectively, these results suggest that immobilized nanotube structures should be considered for further investigation as bionic components...
  2. ncbi Aminoglycoside-induced degeneration of adult spiral ganglion neurons involves differential modulation of tyrosine kinase B and p75 neurotrophin receptor signaling
    Justin Tan
    Department of Otolaryngology, 32 Gisborne St, East Melbourne, Victoria 3002, Australia
    Am J Pathol 169:528-43. 2006
    ..Together, these data suggest that an antagonistic interplay of p75NTR and TrkB receptor signaling, possibly modulated by selective BDNF processing, mediates SGN death in vivo...
  3. ncbi Cochlear implants stimulate activity-dependent CREB pathway in the deaf auditory cortex: implications for molecular plasticity induced by neural prosthetic devices
    Justin Tan
    The Bionic Ear Institute, East Melbourne, Victoria 3002, Australia
    Cereb Cortex 18:1799-813. 2008
    ..These findings provide insights into adaptive, molecular mechanisms recruited by the brain upon functional electrical stimulation by neural prosthetic devices...
  4. ncbi The p75 neurotrophin receptor protects primary auditory neurons against acoustic trauma in mice
    Justin Tan
    The Bionic Ear Institute, 384 388 Albert St, East Melbourne, Victoria 3002, Australia
    Hear Res 268:46-59. 2010
    ..Therefore, our data do not support a role of p75NTR as a death inducer in PANs but show its crucial role in protecting PANs...
  5. ncbi Biocompatibility of immobilized aligned carbon nanotubes
    David A X Nayagam
    The Bionic Ear Institute, 384 388 Albert Street, East Melbourne, 3002, Australia
    Small 7:1035-42. 2011
    ..Collectively, these results suggest that immobilized nanotube structures should be considered for further investigation as bionic components...
  6. ncbi Nanoporous peptide particles for encapsulating and releasing neurotrophic factors in an animal model of neurodegeneration
    Justin Tan
    Bionics Institute, East Melbourne, Victoria 3002, Australia
    Adv Mater 24:3362-6. 2012
    ..Animal experiments demonstrate the released BDNF can efficiently rescue the auditory neurons (as indicated by the arrows) in the cochlea of guinea pigs with sensorineural hearing loss...
  7. ncbi Thyroxine treatments do not correct inner ear defects in tmprss1 mutant mice
    Syazana Hanifa
    The Bionic Ear Institute, University of Melbourne, East Melbourne, Victoria, Australia
    Neuroreport 21:897-901. 2010
    ..Both the treatments could not ameliorate hearing loss or correct deformities in the tectorial membrane of these mutant mice, suggesting that a deficiency in tmprss1 affects thyroxine responsiveness in the inner ear in vivo...
  8. ncbi Lack of Bdnf and TrkB signalling in the postnatal cochlea leads to a spatial reshaping of innervation along the tonotopic axis and hearing loss
    Thomas Schimmang
    Center for Molecular Neurobiology Hamburg, University of Hamburg, Falkenreid, Hamburg, Germany
    Development 130:4741-50. 2003
    ..Our results indicate a substantial potential for re-innervation processes in the mature cochlea, which may also be of relevance for treatment of hearing loss in humans...
  9. ncbi BDNF mRNA expression and protein localization are changed in age-related hearing loss
    Lukas Ruttiger
    Molecular Neurobiology, Tübingen Hearing Research Center, Department of Otorhinolaryngology, University of Tubingen, Tubingen, Germany
    Neurobiol Aging 28:586-601. 2007
    ..Our results suggest that reduced BDNF protein levels in auditory nerves over age may be a crucial factor in the altered brainstem plasticity observed during presbycusis...
  10. ncbi Midazolam reverses salicylate-induced changes in brain-derived neurotrophic factor and arg3.1 expression: implications for tinnitus perception and auditory plasticity
    Rama Panford-Walsh
    Department of Otorhinolaryngology, Universitat Tubingen, Tubingen, Germany
    Mol Pharmacol 74:595-604. 2008
    ..1 and BDNF as markers for activity changes in the auditory system and suggest a role of GABAergic inhibition of cochlear neurons in the modulation of Arg3.1 plasticity changes in the auditory cortex and tinnitus perception...
  11. ncbi Herpes simplex virus type 1-mediated transfer of neurotrophin-3 stimulates survival of chicken auditory sensory neurons
    Estela Carnicero
    , Universidad de Valladolid y Consejo Superior de Investigaciones Cientificas, , , Facultad de Medicina, 47005 Valladolid, Spain
    Neurosci Lett 321:149-52. 2002
    ..Therefore, this vector may present a unique entry point to develop therapies preventing or treating hearing impairment caused by the degeneration of auditory neurons...