Gianluca Severi

Summary

Affiliation: The Cancer Council Victoria
Country: Australia

Publications

  1. ncbi request reprint After hMSH2 and hMLH1--what next? Analysis of three-generational, population-based, early-onset colorectal cancer families
    Mark A Jenkins
    Centre for Genetic Epidemiology, The University of Melbourne, 723 Swanston Street, Carlton Victoria 3053, Australia
    Int J Cancer 102:166-71. 2002
  2. doi request reprint Circulating steroid hormone concentrations in postmenopausal women in relation to body size and composition
    Laura Baglietto
    Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Vic, Australia
    Breast Cancer Res Treat 115:171-9. 2009
  3. pmc A review of the reporting and handling of missing data in cohort studies with repeated assessment of exposure measures
    Amalia Karahalios
    Cancer Epidemiology Centre, Cancer Council Victoria, Carlton, Vic, Australia
    BMC Med Res Methodol 12:96. 2012
  4. pmc Assessing interactions between the associations of common genetic susceptibility variants, reproductive history and body mass index with breast cancer risk in the breast cancer association consortium: a combined case-control study
    Roger L Milne
    Genetic and Molecular Epidemiology Group, Human Cancer Genetics Programme, Spanish National Cancer Research Centre CNIO, Madrid, 28029, Spain
    Breast Cancer Res 12:R110. 2010
  5. pmc A PALB2 mutation associated with high risk of breast cancer
    Melissa C Southey
    Department of Pathology, The University of Melbourne, Victoria 3010, Australia
    Breast Cancer Res 12:R109. 2010
  6. doi request reprint Circulating steroid hormone levels and risk of breast cancer for postmenopausal women
    Laura Baglietto
    Cancer Epidemiology Centre, The Cancer Council Victoria, Victoria, Melbourne, Australia
    Cancer Epidemiol Biomarkers Prev 19:492-502. 2010
  7. pmc Dietary patterns and risk of breast cancer
    L Baglietto
    Cancer Epidemiology Centre, The Cancer Council Victoria, 100 Drummond Street, Carlton, Melbourne, Victoria 3053, Australia
    Br J Cancer 104:524-31. 2011
  8. ncbi request reprint Measures of familial aggregation depend on definition of family history: meta-analysis for colorectal cancer
    Laura Baglietto
    Cancer Epidemiology Centre, The Cancer Council of Victoria, 100 Rathdowne Street, Carlton, Melbourne, Victoria 3053, Australia
    J Clin Epidemiol 59:114-24. 2006
  9. pmc Does dietary folate intake modify effect of alcohol consumption on breast cancer risk? Prospective cohort study
    Laura Baglietto
    Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, 100 Drummond Street, Carlton, Victoria 3053, Australia
    BMJ 331:807. 2005
  10. doi request reprint Dietary intake of B vitamins and methionine and prostate cancer incidence and mortality
    Julie K Bassett
    Cancer Epidemiology Centre, Cancer Council Victoria, 1 Rathdowne Street, Carlton, VIC 3053, Australia
    Cancer Causes Control 23:855-63. 2012

Detail Information

Publications49

  1. ncbi request reprint After hMSH2 and hMLH1--what next? Analysis of three-generational, population-based, early-onset colorectal cancer families
    Mark A Jenkins
    Centre for Genetic Epidemiology, The University of Melbourne, 723 Swanston Street, Carlton Victoria 3053, Australia
    Int J Cancer 102:166-71. 2002
    ..There is evidence for a role of yet to be identified genes associated with a high recessively-inherited risk of colorectal cancer...
  2. doi request reprint Circulating steroid hormone concentrations in postmenopausal women in relation to body size and composition
    Laura Baglietto
    Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Vic, Australia
    Breast Cancer Res Treat 115:171-9. 2009
    ..This effect requires around 6 years to be detectable by way of circulating steroid hormone levels...
  3. pmc A review of the reporting and handling of missing data in cohort studies with repeated assessment of exposure measures
    Amalia Karahalios
    Cancer Epidemiology Centre, Cancer Council Victoria, Carlton, Vic, Australia
    BMC Med Res Methodol 12:96. 2012
    ..We have conducted a review of publications from cohort studies in order to document the reporting of missing data for exposure measures and to describe the statistical methods used to account for the missing data...
  4. pmc Assessing interactions between the associations of common genetic susceptibility variants, reproductive history and body mass index with breast cancer risk in the breast cancer association consortium: a combined case-control study
    Roger L Milne
    Genetic and Molecular Epidemiology Group, Human Cancer Genetics Programme, Spanish National Cancer Research Centre CNIO, Madrid, 28029, Spain
    Breast Cancer Res 12:R110. 2010
    ....
  5. pmc A PALB2 mutation associated with high risk of breast cancer
    Melissa C Southey
    Department of Pathology, The University of Melbourne, Victoria 3010, Australia
    Breast Cancer Res 12:R109. 2010
    ..Little is known about by how much or whether risk differs by mutation or family history, owing to the paucity of studies of cases unselected for family history...
  6. doi request reprint Circulating steroid hormone levels and risk of breast cancer for postmenopausal women
    Laura Baglietto
    Cancer Epidemiology Centre, The Cancer Council Victoria, Victoria, Melbourne, Australia
    Cancer Epidemiol Biomarkers Prev 19:492-502. 2010
    ....
  7. pmc Dietary patterns and risk of breast cancer
    L Baglietto
    Cancer Epidemiology Centre, The Cancer Council Victoria, 100 Drummond Street, Carlton, Melbourne, Victoria 3053, Australia
    Br J Cancer 104:524-31. 2011
    ..Evidence is emerging that prudent/healthy dietary patterns might be associated with a reduced risk of breast cancer...
  8. ncbi request reprint Measures of familial aggregation depend on definition of family history: meta-analysis for colorectal cancer
    Laura Baglietto
    Cancer Epidemiology Centre, The Cancer Council of Victoria, 100 Rathdowne Street, Carlton, Melbourne, Victoria 3053, Australia
    J Clin Epidemiol 59:114-24. 2006
    ....
  9. pmc Does dietary folate intake modify effect of alcohol consumption on breast cancer risk? Prospective cohort study
    Laura Baglietto
    Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, 100 Drummond Street, Carlton, Victoria 3053, Australia
    BMJ 331:807. 2005
    ..To evaluate the effect of dietary folate intake on the relation between alcohol consumption and breast cancer risk...
  10. doi request reprint Dietary intake of B vitamins and methionine and prostate cancer incidence and mortality
    Julie K Bassett
    Cancer Epidemiology Centre, Cancer Council Victoria, 1 Rathdowne Street, Carlton, VIC 3053, Australia
    Cancer Causes Control 23:855-63. 2012
    ..We investigated prospectively the relationship between dietary intakes of methionine, B vitamins associated with one-carbon metabolism, and risk of incident and fatal prostate cancer...
  11. ncbi request reprint Circulating steroid hormones and the risk of prostate cancer
    Gianluca Severi
    Cancer Epidemiology Centre, The Cancer Council Victoria, University of Melbourne, Melbourne, Australia
    Cancer Epidemiol Biomarkers Prev 15:86-91. 2006
    ..06, 0.2, and 0.1, respectively). High levels of testosterone and adrenal androgens are thus associated with reduced risk of aggressive prostate cancer but not with nonaggressive disease...
  12. doi request reprint Weight change and prostate cancer incidence and mortality
    Julie K Bassett
    Cancer Epidemiology Centre, Cancer Council Victoria, Carlton South, Vic, Australia
    Int J Cancer 131:1711-9. 2012
    ..84, 95% CI: 1.09-3.09. Higher adult weight and BMI increases the risk of aggressive prostate cancer and mortality from prostate cancer. Weight gain during adult life is associated with increased prostate cancer mortality...
  13. ncbi request reprint The common variant rs1447295 on chromosome 8q24 and prostate cancer risk: results from an Australian population-based case-control study
    Gianluca Severi
    Cancer Epidemiology Centre, The Cancer Council Victoria, 1 Rathdowne Street, Carlton, Victoria 3053, Australia
    Cancer Epidemiol Biomarkers Prev 16:610-2. 2007
    ....
  14. ncbi request reprint Circulating insulin-like growth factor-I and binding protein-3 and risk of prostate cancer
    Gianluca Severi
    Cancer Epidemiology Centre, Cancer Council Victoria, 1 Rathdowne Street, Carlton, Victoria 3053, Australia
    Cancer Epidemiol Biomarkers Prev 15:1137-41. 2006
    ..49 (95% confidence interval, 1.11-2.00). The HRs did not differ by tumor aggressiveness or age at onset (all Ps > or = 0.4). In our study, high levels of IGFBP-3 but not IGF-I were associated with an increased risk of prostate cancer...
  15. pmc Second to fourth digit ratio (2D:4D) and concentrations of circulating sex hormones in adulthood
    David C Muller
    Cancer Epidemiology Centre, The Cancer Council of Victoria, Melbourne, Australia
    Reprod Biol Endocrinol 9:57. 2011
    ..The objective of this study was to examine whether circulating concentrations of sex hormones and SHBG measured in adulthood was associated with 2D:4D...
  16. doi request reprint No strong association between second to fourth digit ratio (2D:4D) and adult anthropometric measures with emphasis on adiposity
    David C Muller
    Cancer Epidemiology Centre, Cancer Council of Victoria, Melbourne, Australia
    Ann Hum Biol 40:201-4. 2013
    ..This report aimed to assess whether second to fourth digit ratio (2D:4D) is associated with adult anthropometric measures and, in particular, measurements of adiposity...
  17. doi request reprint Age-dependent associations between androgenetic alopecia and prostate cancer risk
    David C Muller
    Cancer Epidemiology Centre, Cancer Council of Victoria, Australia
    Cancer Epidemiol Biomarkers Prev 22:209-15. 2013
    ..We aimed to assess whether androgenetic alopecia at ages 20 and 40 years are associated with risk of prostate cancer...
  18. pmc Population-based estimate of prostate cancer risk for carriers of the HOXB13 missense mutation G84E
    Robert J Macinnis
    Cancer Epidemiology Centre, Cancer Council Victoria, Victoria, Australia
    PLoS ONE 8:e54727. 2013
    ....
  19. ncbi request reprint Variants in the prostate-specific antigen (PSA) gene and prostate cancer risk, survival, and circulating PSA
    Gianluca Severi
    Cancer Epidemiology Center, The Cancer Council Victoria, Melbourne, Victoria, Australia
    Cancer Epidemiol Biomarkers Prev 15:1142-7. 2006
    ..The genotypes and haplotypes studied might be associated with the PSA gene function or be in linkage disequilibrium with other unmeasured and functional variants in the PSA or other genes...
  20. doi request reprint Dietary patterns and prostate cancer risk
    David C Muller
    Cancer Epidemiology Centre, The Cancer Council of Victoria and Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Melbourne, Australia
    Cancer Epidemiol Biomarkers Prev 18:3126-9. 2009
    ..87 to 1.14 and all 95% confidence intervals included 1. The analyses by aggressiveness, Gleason score groups, and age at diagnosis did not show any association (all P(trend) > 0.07)...
  21. ncbi request reprint Early growth, adult body size and prostate cancer risk
    Graham G Giles
    Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia
    Int J Cancer 103:241-5. 2003
    ....
  22. ncbi request reprint Foods, nutrients and prostate cancer
    Allison M Hodge
    Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Australia
    Cancer Causes Control 15:11-20. 2004
    ..To examine the risk of prostate cancer associated with foods and nutrients, including individual fatty acids and carotenoids...
  23. ncbi request reprint The rs743572 common variant in the promoter of CYP17A1 is not associated with prostate cancer risk or circulating hormonal levels
    Gianluca Severi
    Cancer Epidemiology Centre, The Cancer Council Victoria, Carlton, Victoria 3053, Australia
    BJU Int 101:492-6. 2008
    ..To use a large population-based case-control study to test the association between the common genetic variant rs743572 (-34 T to C), prostate cancer risk and circulating levels of several hormones...
  24. ncbi request reprint Alcohol consumption and prostate cancer risk: results from the Melbourne collaborative cohort study
    Laura Baglietto
    Cancer Epidemiology Centre, Cancer Council of Victoria, Melbourne, Vic, Australia
    Int J Cancer 119:1501-4. 2006
    ..Our results show that alcohol consumption does not influence overall prostate cancer incidence but we found suggestive evidence that alcohol consumption might decrease the incidence of aggressive prostate cancer and mortality...
  25. doi request reprint Body size, weight change, and risk of colon cancer
    Julie K Bassett
    Cancer Epidemiology Centre, Cancer Council Victoria, Carlton, Victoria, Australia
    Cancer Epidemiol Biomarkers Prev 19:2978-86. 2010
    ..Few studies have investigated effects of weight change on colon cancer risk...
  26. doi request reprint Asthma, asthma medications, and prostate cancer risk
    Gianluca Severi
    Cancer Epidemiology Centre, The Cancer Council of Victoria, Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Carlton, VIC 3053, Australia
    Cancer Epidemiol Biomarkers Prev 19:2318-24. 2010
    ..The aim of this study was to assess whether a history of asthma or the use of asthma medications is associated with prostate cancer risk...
  27. doi request reprint Alcohol consumption and risk of glioblastoma; evidence from the Melbourne Collaborative Cohort Study
    Laura Baglietto
    Cancer Epidemiology Centre, The Cancer Council of Victoria, Melbourne, Australia
    Int J Cancer 128:1929-34. 2011
    ..79 (0.81 to 3.95) for 20 to 39 g/day, 3.07 (1.26 to 7.47) for 40 to 59 g/day and 2.54 (0.92 to 7.00) for 60 or more g/day. Alcohol consumption at baseline was associated with the risk of glioblastoma in a dose-response relationship...
  28. doi request reprint Consumption of animal products, their nutrient components and postmenopausal circulating steroid hormone concentrations
    M T Brinkman
    Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Australia
    Eur J Clin Nutr 64:176-83. 2010
    ..We aimed to investigate the association between consumption of animal products and the plasma concentrations of steroid hormones and sex hormone-binding globulin (SHBG)...
  29. doi request reprint Plasma phospholipid fatty acids, dietary fatty acids and prostate cancer risk
    Julie K Bassett
    Cancer Epidemiology Centre, Cancer Council Victoria, Carlton, Vic, Australia
    Int J Cancer 133:1882-91. 2013
    ..Higher risks were also observed for dietary n-6 polyunsaturated fats, primarily linoleic acid. ..
  30. doi request reprint Dietary intake of B vitamins and methionine and colorectal cancer risk
    Julie K Bassett
    Cancer Epidemiology Centre, Cancer Council Victoria, Carlton, Victoria, Australia
    Nutr Cancer 65:659-67. 2013
    ..Adequate folate intake might protect against colon cancer risk in those with low methionine intake...
  31. doi request reprint Dietary intake of B vitamins and methionine and breast cancer risk
    Julie K Bassett
    Cancer Epidemiology Centre, Cancer Council Victoria, 1 Rathdowne Street, Carlton, Vic, 3053, Australia
    Cancer Causes Control 24:1555-63. 2013
    ..Interactions between different B vitamins and methionine were also examined...
  32. ncbi request reprint Androgenetic alopecia and prostate cancer: findings from an Australian case-control study
    Graham G Giles
    Cancer Epidemiology Centre, Anti Cancer Council of Victoria, Melbourne, VIC 3053 Australia
    Cancer Epidemiol Biomarkers Prev 11:549-53. 2002
    ..91 (1.59-5.32) for vertex baldness; and 1.95 (1.10-3.45) for frontal and vertex baldness. This association between the pattern of AA and prostate cancer points to shared androgen pathways that are worthy of additional investigation...
  33. pmc Plasma concentration of Propionibacterium acnes antibodies and prostate cancer risk: results from an Australian population-based case-control study
    G Severi
    Cancer Epidemiology Centre, The Cancer Council of Victoria, Melbourne, Victoria 3053, Australia
    Br J Cancer 103:411-5. 2010
    ..The aim of our study was to test whether circulating levels of P. acnes antibodies are associated with prostate cancer risk and tumour characteristics using plasma samples from a population-based case-control study...
  34. doi request reprint A whole of population-based series of radical prostatectomy in Victoria, 1995 to 2000
    Damien Bolton
    Austin Hospital, Melbourne, Victoria
    Aust N Z J Public Health 33:527-33. 2009
    ....
  35. doi request reprint The effect of socioeconomic status on survival from colorectal cancer in the Melbourne Collaborative Cohort Study
    Helen L Kelsall
    The Cancer Council Victoria, Carlton, Victoria 3053, Australia
    Soc Sci Med 68:290-7. 2009
    ....
  36. pmc The use of DNA from archival dried blood spots with the Infinium HumanMethylation450 array
    Jihoon E Joo
    Genetic Epidemiology Laboratory, Department of Pathology, The University of Melbourne, Victoria, 3010, Australia
    BMC Biotechnol 13:23. 2013
    ....
  37. ncbi request reprint Cancer risks for mismatch repair gene mutation carriers: a population-based early onset case-family study
    Mark A Jenkins
    Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Victoria, Australia
    Clin Gastroenterol Hepatol 4:489-98. 2006
    ..These may be overestimates, due to analytic problems, and not generalizable. We estimated average cancer risks for mutations identified in population-based early onset colorectal cancer cases (probands) unselected for family history...
  38. ncbi request reprint Average volume of alcohol consumed, type of beverage, drinking pattern and the risk of death from all causes
    Laura Baglietto
    Cancer Epidemiology Centre, The Cancer Council of Victoria, Carlton VIC 3053, Melbourne, Australia
    Alcohol Alcohol 41:664-71. 2006
    ..The objective was to investigate associations between average volume of alcohol consumption, type of beverage and drinking pattern and all-cause mortality in the Melbourne Collaborative Cohort Study...
  39. ncbi request reprint Circulating insulin-like growth factor-I and binding protein-3 and the risk of breast cancer
    Laura Baglietto
    Cancer Epidemiology Centre, The Cancer Council Victoria, 1 Rathdowne Street, Carlton, Melbourne, Victoria 3053, Australia
    Cancer Epidemiol Biomarkers Prev 16:763-8. 2007
    ..More prospective studies are needed to clarify the age dependence of the association between IGF-I and IGFBP-3 and breast cancer...
  40. pmc Risks of Lynch syndrome cancers for MSH6 mutation carriers
    Laura Baglietto
    Cancer Epidemiology Centre, Victorian Cancer Registry, Carlton, Victoria, Australia
    J Natl Cancer Inst 102:193-201. 2010
    ..Germline mutations in MSH6 account for 10%-20% of Lynch syndrome colorectal cancers caused by hereditary DNA mismatch repair gene mutations. Because there have been only a few studies of mutation carriers, their cancer risks are uncertain...
  41. ncbi request reprint Effect of the synthetic retinoid fenretinide on circulating free prostate-specific antigen, insulin-like growth factor-I, and insulin-like growth factor binding protein-3 levels in men with superficial bladder cancer
    Davide Serrano
    Division of Chemoprevention, Cancer Epidemiology Center, Cancer Council of Victoria, Melbourne, Australia
    Clin Cancer Res 11:2083-8. 2005
    ..Fenretinide (4-HPR) is a synthetic retinoid that has shown a preventive activity in prostate cancer animal models...
  42. pmc Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics
    Montserrat Garcia-Closas
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Marylan, United States of America
    PLoS Genet 4:e1000054. 2008
    ..Understanding the etiologic heterogeneity of breast cancer may ultimately result in improvements in prevention, early detection, and treatment...
  43. pmc The clinical phenotype of Lynch syndrome due to germ-line PMS2 mutations
    Leigha Senter
    Human Cancer Genetics Program, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, USA
    Gastroenterology 135:419-28. 2008
    ..Information about the clinical significance of PMS2 mutations is crucial for appropriate counseling. Here, we report the clinical characteristics of a large series of PMS2 mutation carriers...
  44. ncbi request reprint A phase I-II preoperative biomarker trial of fenretinide in ascitic ovarian cancer
    Nicoletta Colombo
    Division of Gynecologic Oncology, European Institute of Oncology, Milan, Italy
    Cancer Epidemiol Biomarkers Prev 15:1914-9. 2006
    ....
  45. ncbi request reprint Segregation analysis of urothelial cell carcinoma
    Katja K H Aben
    Dept of Epidemiology and Biostatistics, Radboud University, Nijmegen Medical Centre, PO Box 9101, 6500 HB Nijmegen, The Netherlands
    Eur J Cancer 42:1428-33. 2006
    ..The 'no major gene' (or sporadic) model appeared to be the most parsimonious one to describe the occurrence of UCC in these families...
  46. ncbi request reprint Relationships between circulating hormone levels, mammographic percent density and breast cancer risk factors in postmenopausal women
    Harriet Johansson
    Division of Cancer Prevention and Genetics, European Institute of Oncology, Milan, Italy
    Breast Cancer Res Treat 108:57-67. 2008
    ..The aim of this study was to assess the relationships between circulating hormones, clinical features related to breast cancer risk and mammographic density in postmenopausal women...
  47. ncbi request reprint Effects of raloxifene on sex steroid hormones and C-telopeptide in postmenopausal women with primary breast cancer
    Harriet Johansson
    Division of Chemoprevention, European Institute of Oncology, Milan, Italy
    Breast Cancer Res Treat 98:167-72. 2006
    ..024) and E2 (p=0.01), and positively with DHEA-S (p=0.016) and CTX (p=0.040). Our results provide evidence for an early endocrine effect of raloxifene which further suggests a favorable impact on breast cancer prevention...
  48. ncbi request reprint Factors associated with circulating levels of insulin-like growth factor-I and insulin-like growth factor binding protein-3 in 740 women at risk for breast cancer
    Harriet Johansson
    Division of Chemoprevention, European Institute of Oncology, Milan, Italy
    Breast Cancer Res Treat 88:63-73. 2004
    ..These findings support their putative role as breast cancer risk biomarker...
  49. ncbi request reprint A two-by-two factorial trial comparing oral with transdermal estrogen therapy and fenretinide with placebo on breast cancer biomarkers
    Andrea Decensi
    Divisions of Chemoprevention, Epidemiology and Biostatistics, Laboratory Medicine, Radiology, and Gynecology, European Institute of Oncology, Milan, Italy
    Clin Cancer Res 10:4389-97. 2004
    ....