Research Topics
Species | Gianluca SeveriSummaryAffiliation: The Cancer Council Victoria Country: Australia Publications
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Detail Information
Publications
After hMSH2 and hMLH1--what next? Analysis of three-generational, population-based, early-onset colorectal cancer familiesMark A Jenkins
Centre for Genetic Epidemiology, The University of Melbourne, 723 Swanston Street, Carlton Victoria 3053, Australia
Int J Cancer 102:166-71. 2002..There is evidence for a role of yet to be identified genes associated with a high recessively-inherited risk of colorectal cancer...
Circulating steroid hormone concentrations in postmenopausal women in relation to body size and compositionLaura Baglietto
Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Vic, Australia
Breast Cancer Res Treat 115:171-9. 2009..This effect requires around 6 years to be detectable by way of circulating steroid hormone levels...
Assessing interactions between the associations of common genetic susceptibility variants, reproductive history and body mass index with breast cancer risk in the breast cancer association consortium: a combined case-control studyRoger L Milne
Genetic and Molecular Epidemiology Group, Human Cancer Genetics Programme, Spanish National Cancer Research Centre CNIO, Madrid, 28029, Spain
Breast Cancer Res 12:R110. 2010....- A PALB2 mutation associated with high risk of breast cancerMelissa C Southey
Department of Pathology, The University of Melbourne, Victoria 3010, Australia
Breast Cancer Res 12:R109. 2010..Little is known about by how much or whether risk differs by mutation or family history, owing to the paucity of studies of cases unselected for family history... - Circulating steroid hormone levels and risk of breast cancer for postmenopausal womenLaura Baglietto
Cancer Epidemiology Centre, The Cancer Council Victoria, Victoria, Melbourne, Australia
Cancer Epidemiol Biomarkers Prev 19:492-502. 2010.... - Dietary patterns and risk of breast cancerL Baglietto
Cancer Epidemiology Centre, The Cancer Council Victoria, 100 Drummond Street, Carlton, Melbourne, Victoria 3053, Australia
Br J Cancer 104:524-31. 2011..Evidence is emerging that prudent/healthy dietary patterns might be associated with a reduced risk of breast cancer... - Measures of familial aggregation depend on definition of family history: meta-analysis for colorectal cancerLaura Baglietto
Cancer Epidemiology Centre, The Cancer Council of Victoria, 100 Rathdowne Street, Carlton, Melbourne, Victoria 3053, Australia
J Clin Epidemiol 59:114-24. 2006.... - Does dietary folate intake modify effect of alcohol consumption on breast cancer risk? Prospective cohort studyLaura Baglietto
Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, 100 Drummond Street, Carlton, Victoria 3053, Australia
BMJ 331:807. 2005..To evaluate the effect of dietary folate intake on the relation between alcohol consumption and breast cancer risk... - Dietary intake of B vitamins and methionine and prostate cancer incidence and mortalityJulie K Bassett
Cancer Epidemiology Centre, Cancer Council Victoria, 1 Rathdowne Street, Carlton, VIC 3053, Australia
Cancer Causes Control 23:855-63. 2012..We investigated prospectively the relationship between dietary intakes of methionine, B vitamins associated with one-carbon metabolism, and risk of incident and fatal prostate cancer... - Circulating steroid hormones and the risk of prostate cancerGianluca Severi
Cancer Epidemiology Centre, The Cancer Council Victoria, University of Melbourne, Melbourne, Australia
Cancer Epidemiol Biomarkers Prev 15:86-91. 2006..06, 0.2, and 0.1, respectively). High levels of testosterone and adrenal androgens are thus associated with reduced risk of aggressive prostate cancer but not with nonaggressive disease... - Weight change and prostate cancer incidence and mortalityJulie K Bassett
Cancer Epidemiology Centre, Cancer Council Victoria, Carlton South, Vic, Australia
Int J Cancer 131:1711-9. 2012..84, 95% CI: 1.09-3.09. Higher adult weight and BMI increases the risk of aggressive prostate cancer and mortality from prostate cancer. Weight gain during adult life is associated with increased prostate cancer mortality... - The common variant rs1447295 on chromosome 8q24 and prostate cancer risk: results from an Australian population-based case-control studyGianluca Severi
Cancer Epidemiology Centre, The Cancer Council Victoria, 1 Rathdowne Street, Carlton, Victoria 3053, Australia
Cancer Epidemiol Biomarkers Prev 16:610-2. 2007.... - Circulating insulin-like growth factor-I and binding protein-3 and risk of prostate cancerGianluca Severi
Cancer Epidemiology Centre, Cancer Council Victoria, 1 Rathdowne Street, Carlton, Victoria 3053, Australia
Cancer Epidemiol Biomarkers Prev 15:1137-41. 2006..49 (95% confidence interval, 1.11-2.00). The HRs did not differ by tumor aggressiveness or age at onset (all Ps > or = 0.4). In our study, high levels of IGFBP-3 but not IGF-I were associated with an increased risk of prostate cancer... - Second to fourth digit ratio (2D:4D) and concentrations of circulating sex hormones in adulthoodDavid C Muller
Cancer Epidemiology Centre, The Cancer Council of Victoria, Melbourne, Australia
Reprod Biol Endocrinol 9:57. 2011..The objective of this study was to examine whether circulating concentrations of sex hormones and SHBG measured in adulthood was associated with 2D:4D... - Dietary patterns and prostate cancer riskDavid C Muller
Cancer Epidemiology Centre, The Cancer Council of Victoria and Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Melbourne, Australia
Cancer Epidemiol Biomarkers Prev 18:3126-9. 2009..87 to 1.14 and all 95% confidence intervals included 1. The analyses by aggressiveness, Gleason score groups, and age at diagnosis did not show any association (all P(trend) > 0.07)... - Early growth, adult body size and prostate cancer riskGraham G Giles
Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia
Int J Cancer 103:241-5. 2003.... - Variants in the prostate-specific antigen (PSA) gene and prostate cancer risk, survival, and circulating PSAGianluca Severi
Cancer Epidemiology Center, The Cancer Council Victoria, Melbourne, Victoria, Australia
Cancer Epidemiol Biomarkers Prev 15:1142-7. 2006..The genotypes and haplotypes studied might be associated with the PSA gene function or be in linkage disequilibrium with other unmeasured and functional variants in the PSA or other genes... - Foods, nutrients and prostate cancerAllison M Hodge
Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Australia
Cancer Causes Control 15:11-20. 2004..CONCLUSIONS: Based on these findings, diets rich in olive oil (a source of oleic acid), tomatoes and allium vegetables might reduce the risk of prostate cancer... - The rs743572 common variant in the promoter of CYP17A1 is not associated with prostate cancer risk or circulating hormonal levelsGianluca Severi
Cancer Epidemiology Centre, The Cancer Council Victoria, Carlton, Victoria 3053, Australia
BJU Int 101:492-6. 2008..To use a large population-based case-control study to test the association between the common genetic variant rs743572 (-34 T to C), prostate cancer risk and circulating levels of several hormones... - Asthma, asthma medications, and prostate cancer riskGianluca Severi
Cancer Epidemiology Centre, The Cancer Council of Victoria, Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Carlton, VIC 3053, Australia
Cancer Epidemiol Biomarkers Prev 19:2318-24. 2010..The aim of this study was to assess whether a history of asthma or the use of asthma medications is associated with prostate cancer risk... - Body size, weight change, and risk of colon cancerJulie K Bassett
Cancer Epidemiology Centre, Cancer Council Victoria, Carlton, Victoria, Australia
Cancer Epidemiol Biomarkers Prev 19:2978-86. 2010..Few studies have investigated effects of weight change on colon cancer risk... - Alcohol consumption and prostate cancer risk: results from the Melbourne collaborative cohort studyLaura Baglietto
Cancer Epidemiology Centre, Cancer Council of Victoria, Melbourne, Vic, Australia
Int J Cancer 119:1501-4. 2006..Our results show that alcohol consumption does not influence overall prostate cancer incidence but we found suggestive evidence that alcohol consumption might decrease the incidence of aggressive prostate cancer and mortality... - Alcohol consumption and risk of glioblastoma; evidence from the Melbourne Collaborative Cohort StudyLaura Baglietto
Cancer Epidemiology Centre, The Cancer Council of Victoria, Melbourne, Australia
Int J Cancer 128:1929-34. 2011..79 (0.81 to 3.95) for 20 to 39 g/day, 3.07 (1.26 to 7.47) for 40 to 59 g/day and 2.54 (0.92 to 7.00) for 60 or more g/day. Alcohol consumption at baseline was associated with the risk of glioblastoma in a dose-response relationship... - Consumption of animal products, their nutrient components and postmenopausal circulating steroid hormone concentrationsM T Brinkman
Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Australia
Eur J Clin Nutr 64:176-83. 2010..We aimed to investigate the association between consumption of animal products and the plasma concentrations of steroid hormones and sex hormone-binding globulin (SHBG)... - Population-based estimate of prostate cancer risk for carriers of the HOXB13 missense mutation G84ERobert J Macinnis
Cancer Epidemiology Centre, Cancer Council Victoria, Victoria, Australia
PLoS ONE 8:e54727. 2013.... - Age-dependent associations between androgenetic alopecia and prostate cancer riskDavid C Muller
Cancer Epidemiology Centre, Cancer Council of Victoria, Australia
Cancer Epidemiol Biomarkers Prev 22:209-15. 2013..We aimed to assess whether androgenetic alopecia at ages 20 and 40 years are associated with risk of prostate cancer... - No strong association between second to fourth digit ratio (2D:4D) and adult anthropometric measures with emphasis on adiposityDavid C Muller
Cancer Epidemiology Centre, Cancer Council of Victoria, Melbourne, Australia
Ann Hum Biol 40:201-4. 2013..This report aimed to assess whether second to fourth digit ratio (2D:4D) is associated with adult anthropometric measures and, in particular, measurements of adiposity... - Androgenetic alopecia and prostate cancer: findings from an Australian case-control studyGraham G Giles
Cancer Epidemiology Centre, Anti-Cancer Council of Victoria, Melbourne, VIC 3053 Australia
Cancer Epidemiol Biomarkers Prev 11:549-53. 2002..91 (1.59-5.32) for vertex baldness; and 1.95 (1.10-3.45) for frontal and vertex baldness. This association between the pattern of AA and prostate cancer points to shared androgen pathways that are worthy of additional investigation... - Plasma concentration of Propionibacterium acnes antibodies and prostate cancer risk: results from an Australian population-based case-control studyG Severi
Cancer Epidemiology Centre, The Cancer Council of Victoria, Melbourne, Victoria 3053, Australia
Br J Cancer 103:411-5. 2010..The aim of our study was to test whether circulating levels of P. acnes antibodies are associated with prostate cancer risk and tumour characteristics using plasma samples from a population-based case-control study... - A whole of population-based series of radical prostatectomy in Victoria, 1995 to 2000Damien Bolton
Austin Hospital, Melbourne, Victoria
Aust N Z J Public Health 33:527-33. 2009.... - The effect of socioeconomic status on survival from colorectal cancer in the Melbourne Collaborative Cohort StudyHelen L Kelsall
The Cancer Council Victoria, Carlton, Victoria 3053, Australia
Soc Sci Med 68:290-7. 2009.... - The use of DNA from archival dried blood spots with the Infinium HumanMethylation450 arrayJihoon E Joo
Genetic Epidemiology Laboratory, Department of Pathology, The University of Melbourne, Victoria, 3010, Australia
BMC Biotechnol 13:23. 2013.... - Cancer risks for mismatch repair gene mutation carriers: a population-based early onset case-family studyMark A Jenkins
Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Victoria, Australia
Clin Gastroenterol Hepatol 4:489-98. 2006..These may be overestimates, due to analytic problems, and not generalizable. We estimated average cancer risks for mutations identified in population-based early onset colorectal cancer cases (probands) unselected for family history... - Average volume of alcohol consumed, type of beverage, drinking pattern and the risk of death from all causesLaura Baglietto
Cancer Epidemiology Centre, The Cancer Council of Victoria, Carlton VIC 3053, Melbourne, Australia
Alcohol Alcohol 41:664-71. 2006..04). CONCLUSIONS: These results confirm previous findings about the effect of average volume of alcohol and type of beverage and suggest that drinking pattern is an independent risk factor for all-cause mortality... - Circulating insulin-like growth factor-I and binding protein-3 and the risk of breast cancerLaura Baglietto
Cancer Epidemiology Centre, The Cancer Council Victoria, 1 Rathdowne Street, Carlton, Melbourne, Victoria 3053, Australia
Cancer Epidemiol Biomarkers Prev 16:763-8. 2007..More prospective studies are needed to clarify the age dependence of the association between IGF-I and IGFBP-3 and breast cancer... - Risks of Lynch syndrome cancers for MSH6 mutation carriersLaura Baglietto
Cancer Epidemiology Centre, Victorian Cancer Registry, Carlton, Victoria, Australia
J Natl Cancer Inst 102:193-201. 2010..Germline mutations in MSH6 account for 10%-20% of Lynch syndrome colorectal cancers caused by hereditary DNA mismatch repair gene mutations. Because there have been only a few studies of mutation carriers, their cancer risks are uncertain... - Effect of the synthetic retinoid fenretinide on circulating free prostate-specific antigen, insulin-like growth factor-I, and insulin-like growth factor binding protein-3 levels in men with superficial bladder cancerDavide Serrano
Division of Chemoprevention, Cancer Epidemiology Center, Cancer Council of Victoria, Melbourne, Australia
Clin Cancer Res 11:2083-8. 2005..These effects might support an activity in prostate cancer prevention but further studies are required... - A two-by-two factorial trial comparing oral with transdermal estrogen therapy and fenretinide with placebo on breast cancer biomarkersAndrea Decensi
Divisions of Chemoprevention, Epidemiology and Biostatistics, Laboratory Medicine, Radiology, and Gynecology, European Institute of Oncology, Milan, Italy
Clin Cancer Res 10:4389-97. 2004.... - Effects of raloxifene on sex steroid hormones and C-telopeptide in postmenopausal women with primary breast cancerHarriet Johansson
Division of Chemoprevention, European Institute of Oncology, Milan, Italy
Breast Cancer Res Treat 98:167-72. 2006..024) and E2 (p=0.01), and positively with DHEA-S (p=0.016) and CTX (p=0.040). Our results provide evidence for an early endocrine effect of raloxifene which further suggests a favorable impact on breast cancer prevention... - Segregation analysis of urothelial cell carcinomaKatja K H Aben
Dept. of Epidemiology and Biostatistics, Radboud University, Nijmegen Medical Centre, PO Box 9101, 6500 HB Nijmegen, The Netherlands
Eur J Cancer 42:1428-33. 2006..The 'no major gene' (or sporadic) model appeared to be the most parsimonious one to describe the occurrence of UCC in these families... - Factors associated with circulating levels of insulin-like growth factor-I and insulin-like growth factor binding protein-3 in 740 women at risk for breast cancerHarriet Johansson
Division of Chemoprevention, European Institute of Oncology, Milan, Italy
Breast Cancer Res Treat 88:63-73. 2004..These findings support their putative role as breast cancer risk biomarker... - A phase I-II preoperative biomarker trial of fenretinide in ascitic ovarian cancerNicoletta Colombo
Division of Gynecologic Oncology, European Institute of Oncology, Milan, Italy
Cancer Epidemiol Biomarkers Prev 15:1914-9. 2006..Under our experimental conditions, 4-HPR did not show activity in advanced ovarian cancer cells. However, clinical evidence supports further investigation of fenretinide for ovarian cancer prevention... - Relationships between circulating hormone levels, mammographic percent density and breast cancer risk factors in postmenopausal womenHarriet Johansson
Division of Cancer Prevention and Genetics, European Institute of Oncology, Milan, Italy
Breast Cancer Res Treat 108:57-67. 2008..The aim of this study was to assess the relationships between circulating hormones, clinical features related to breast cancer risk and mammographic density in postmenopausal women... - The clinical phenotype of Lynch syndrome due to germ-line PMS2 mutationsLeigha Senter
Human Cancer Genetics Program, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, USA
Gastroenterology 135:419-28. 2008..Information about the clinical significance of PMS2 mutations is crucial for appropriate counseling. Here, we report the clinical characteristics of a large series of PMS2 mutation carriers... - Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristicsMontserrat Garcia-Closas
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Marylan, United States of America
PLoS Genet 4:e1000054. 2008..Understanding the etiologic heterogeneity of breast cancer may ultimately result in improvements in prevention, early detection, and treatment...