Stephen MacMahon

Summary

Affiliation: The George Institute for International Health
Country: Australia

Publications

  1. doi request reprint Blood-pressure-related disease is a global health priority
    Stephen MacMahon
    George Institute for International Health, University of Sydney, Sydney, NSW 2050, Australia
    Lancet 371:1480-2. 2008
  2. pmc Lowering blood pressure reduces renal events in type 2 diabetes
    Bastiaan E De Galan
    George Institute for International Health, University of Sydney, Sydney, NSW, Australia
    J Am Soc Nephrol 20:883-92. 2009
  3. ncbi request reprint Efficacy and safety of routine blood pressure lowering in older patients with diabetes: results from the ADVANCE trial
    Toshiharu Ninomiya
    The George Institute for International Health, University of Sydney, New South Wales, Australia
    J Hypertens 28:1141-9. 2010
  4. ncbi request reprint Perindopril-based blood pressure-lowering reduces major vascular events in patients with atrial fibrillation and prior stroke or transient ischemic attack
    Hisatomi Arima
    George Institute for International Health, University of Sydney, Australia
    Stroke 36:2164-9. 2005
  5. pmc Combined effects of routine blood pressure lowering and intensive glucose control on macrovascular and microvascular outcomes in patients with type 2 diabetes: New results from the ADVANCE trial
    Sophia Zoungas
    The George Institute for International Health, University of Sydney, Sydney, New South Wales, Australia
    Diabetes Care 32:2068-74. 2009
  6. ncbi request reprint Effects of visit-to-visit variability in systolic blood pressure on macrovascular and microvascular complications in patients with type 2 diabetes mellitus: the ADVANCE trial
    Jun Hata
    From The George Institute for Global Health, University of Sydney, Sydney, Australia J H, H A, M W, S Z, C A, A P, B N, S M, J C University of Oxford, Oxford, United Kingdom P M R, S M School of Public Health, Monash University, Clayton, Australia S Z Bond University, Gold Coast, Australia P G Université de Montréal, Montreal, Canada P H University of Milan Bicocca, Milan, Italy G M Imperial College, London, United Kingdom N P and University College London UCL and the National Institute for Health Research UCL Hospitals Biomedical Research Centre, London, United Kingdom B W
    Circulation 128:1325-34. 2013
  7. doi request reprint Effects of perindopril-based lowering of blood pressure on intracerebral hemorrhage related to amyloid angiopathy: the PROGRESS trial
    Hisatomi Arima
    The George Institute for International Health, University of Sydney and The Royal Prince Alfred Hospital, Sydney, Australia
    Stroke 41:394-6. 2010
  8. doi request reprint Fatal and nonfatal cardiovascular disease and the use of therapies for secondary prevention in a rural region of India
    Rohina Joshi
    The George Institute for International Health, Lecturer, Faculty of Medicine, University of Sydney, Sydney, NSW, Australia
    Circulation 119:1950-5. 2009
  9. doi request reprint Severe hypoglycemia and risks of vascular events and death
    Sophia Zoungas
    George Institute for International Health, University of Sydney, Sydney, Australia
    N Engl J Med 363:1410-8. 2010
  10. ncbi request reprint Lower target blood pressures are safe and effective for the prevention of recurrent stroke: the PROGRESS trial
    Hisatomi Arima
    The George Institute for International Health, University of Sydney, Sydney, NSW, Australia
    J Hypertens 24:1201-8. 2006

Collaborators

Detail Information

Publications50

  1. doi request reprint Blood-pressure-related disease is a global health priority
    Stephen MacMahon
    George Institute for International Health, University of Sydney, Sydney, NSW 2050, Australia
    Lancet 371:1480-2. 2008
  2. pmc Lowering blood pressure reduces renal events in type 2 diabetes
    Bastiaan E De Galan
    George Institute for International Health, University of Sydney, Sydney, NSW, Australia
    J Am Soc Nephrol 20:883-92. 2009
    ..We could not identify a BP threshold below which renal benefit is lost...
  3. ncbi request reprint Efficacy and safety of routine blood pressure lowering in older patients with diabetes: results from the ADVANCE trial
    Toshiharu Ninomiya
    The George Institute for International Health, University of Sydney, New South Wales, Australia
    J Hypertens 28:1141-9. 2010
    ....
  4. ncbi request reprint Perindopril-based blood pressure-lowering reduces major vascular events in patients with atrial fibrillation and prior stroke or transient ischemic attack
    Hisatomi Arima
    George Institute for International Health, University of Sydney, Australia
    Stroke 36:2164-9. 2005
    ..The primary objective here is to determine whether routine blood pressure-lowering provides additional protection for this high-risk patient group...
  5. pmc Combined effects of routine blood pressure lowering and intensive glucose control on macrovascular and microvascular outcomes in patients with type 2 diabetes: New results from the ADVANCE trial
    Sophia Zoungas
    The George Institute for International Health, University of Sydney, Sydney, New South Wales, Australia
    Diabetes Care 32:2068-74. 2009
    ..To assess the magnitude and independence of the effects of routine blood pressure lowering and intensive glucose control on clinical outcomes in patients with long-standing type 2 diabetes...
  6. ncbi request reprint Effects of visit-to-visit variability in systolic blood pressure on macrovascular and microvascular complications in patients with type 2 diabetes mellitus: the ADVANCE trial
    Jun Hata
    From The George Institute for Global Health, University of Sydney, Sydney, Australia J H, H A, M W, S Z, C A, A P, B N, S M, J C University of Oxford, Oxford, United Kingdom P M R, S M School of Public Health, Monash University, Clayton, Australia S Z Bond University, Gold Coast, Australia P G Université de Montréal, Montreal, Canada P H University of Milan Bicocca, Milan, Italy G M Imperial College, London, United Kingdom N P and University College London UCL and the National Institute for Health Research UCL Hospitals Biomedical Research Centre, London, United Kingdom B W
    Circulation 128:1325-34. 2013
    ..However, it remains uncertain whether these parameters predict the risks of macrovascular and microvascular complications in patients with type 2 diabetes mellitus...
  7. doi request reprint Effects of perindopril-based lowering of blood pressure on intracerebral hemorrhage related to amyloid angiopathy: the PROGRESS trial
    Hisatomi Arima
    The George Institute for International Health, University of Sydney and The Royal Prince Alfred Hospital, Sydney, Australia
    Stroke 41:394-6. 2010
    ..The objective is to determine whether lowering of blood pressure (BP) provides protection for this high-risk patient group...
  8. doi request reprint Fatal and nonfatal cardiovascular disease and the use of therapies for secondary prevention in a rural region of India
    Rohina Joshi
    The George Institute for International Health, Lecturer, Faculty of Medicine, University of Sydney, Sydney, NSW, Australia
    Circulation 119:1950-5. 2009
    ..Precise and reliable data on fatal and nonfatal cardiovascular disease, however, are few, and little is known about the use of preventive therapies. This is particularly true for rural regions...
  9. doi request reprint Severe hypoglycemia and risks of vascular events and death
    Sophia Zoungas
    George Institute for International Health, University of Sydney, Sydney, Australia
    N Engl J Med 363:1410-8. 2010
    ..We analyzed data from a large study of intensive glucose lowering to explore the relationship between severe hypoglycemia and adverse clinical outcomes...
  10. ncbi request reprint Lower target blood pressures are safe and effective for the prevention of recurrent stroke: the PROGRESS trial
    Hisatomi Arima
    The George Institute for International Health, University of Sydney, Sydney, NSW, Australia
    J Hypertens 24:1201-8. 2006
    ..To explore the likely optimum blood pressure (BP) level for patients with a history of cerebrovascular disease...
  11. ncbi request reprint Prior events predict cerebrovascular and coronary outcomes in the PROGRESS trial
    Hisatomi Arima
    The George Institute for International Health, University of Sydney, Australia
    Stroke 37:1497-502. 2006
    ..We examined the relationship between initial event and various types of further vascular outcomes and associated effects of blood pressure (BP)-lowering...
  12. pmc Effects of the endpoint adjudication process on the results of a randomised controlled trial: the ADVANCE trial
    Jun Hata
    The George Institute for Global Health, University of Sydney, Sydney, New South Wales, Australia
    PLoS ONE 8:e55807. 2013
    ..The aim of the present analysis is to assess the effects of the endpoint adjudication process on the main findings of the ADVANCE trial (Trial registration: ClinicalTrials.gov NCT00145925)...
  13. ncbi request reprint Intensive glucose control improves kidney outcomes in patients with type 2 diabetes
    Vlado Perkovic
    The George Institute for Global Health, University of Sydney, Sydney, New South Wales, Australia
    Kidney Int 83:517-23. 2013
    ..Thus, improved glucose control will improve major kidney outcomes in patients with type 2 diabetes...
  14. pmc The PROGRESS trial three years later: time for more action, less distraction
    Stephen MacMahon
    The George Institute for International Health, University of Sydney, PO Box M201, Sydney, NSW 2050, Australia
    BMJ 329:970-1. 2004
  15. doi request reprint The Framingham Study, diabetes mellitus and cardiovascular disease: turning back the clock
    Andre Pascal Kengne
    The George Institute for International Health, The University of Sydney, Camperdown, Sydney, NSW, Australia
    Prog Cardiovasc Dis 53:45-51. 2010
    ..Lines of investigation regarding cardiovascular health in this population are still wide open, and the Framingham Study continues to be part of this journey...
  16. doi request reprint The effects of blood pressure reduction and of different blood pressure-lowering regimens on major cardiovascular events according to baseline blood pressure: meta-analysis of randomized trials
    Sebastien Czernichow
    The George Institute, Sydney, Australia
    J Hypertens 29:4-16. 2011
    ..The objective was to compare the risk reductions achieved by different blood pressure-lowering regimens among individuals with different baseline blood pressures...
  17. pmc Effects of intensive blood pressure lowering on cardiovascular and renal outcomes: a systematic review and meta-analysis
    Jicheng Lv
    The George Institute for Global Health, The University of Sydney, Sydney, Australia
    PLoS Med 9:e1001293. 2012
    ..We did a systematic review to assess the effects of intensive BP lowering on vascular, eye, and renal outcomes...
  18. doi request reprint Blood pressure and cardiovascular disease: tracing the steps from Framingham
    Fiona Turnbull
    Cardiovascular Division, The George Institute for International Health, Camperdown, NSW 2050, Australia
    Prog Cardiovasc Dis 53:39-44. 2010
    ..Much of our current understanding of the role blood pressure in cardiovascular disease can be attributed to decades of high quality research from Framingham...
  19. pmc Albuminuria and kidney function independently predict cardiovascular and renal outcomes in diabetes
    Toshiharu Ninomiya
    George Institute for International Health, University of Sydney, Sydney, NSW, Australia
    J Am Soc Nephrol 20:1813-21. 2009
    ..In conclusion, high albuminuria and low eGFR are independent risk factors for cardiovascular and renal events among patients with type 2 diabetes...
  20. ncbi request reprint Chronic kidney disease, cardiovascular events, and the effects of perindopril-based blood pressure lowering: data from the PROGRESS study
    Vlado Perkovic
    George Institute for International Health, PO Box M201, Sydney, Australia, 2050
    J Am Soc Nephrol 18:2766-72. 2007
    ..In conclusion, kidney function should be considered when determining the need for blood pressure lowering therapy in patients with cerebrovascular disease...
  21. ncbi request reprint Clinical implications of PROGRESS: questions and answers
    John Chalmers
    Institute for International Health, University of Sydney, Newtown, NSW, Australia
    J Hypertens Suppl 21:S21-4. 2003
  22. ncbi request reprint Effects of different blood pressure-lowering regimens on major cardiovascular events in individuals with and without diabetes mellitus: results of prospectively designed overviews of randomized trials
    Fiona Turnbull
    The George Institute for International Health, University of Sydney, New South Wales, Australia
    Arch Intern Med 165:1410-9. 2005
    ..The overviews reported herein were performed to formally compare the effects on cardiovascular events and death of different BP-lowering regimens in individuals with and without diabetes...
  23. ncbi request reprint Perindopril pROtection aGainst REcurrent Stroke Study (PROGRESS): interpretation and implementation
    John Chalmers
    Institute for International Health, University of Sydney, Newtown, NSW, Australia
    J Hypertens Suppl 21:S9-14. 2003
    ..To determine the effects of a perindopril-based blood pressure lowering regimen in hypertensive and non-hypertensive patients with a history of stroke or transient ischaemic attack (TIA)...
  24. doi request reprint Global inequalities in access to cardiovascular health care: our greatest challenge
    Rohina Joshi
    The George Institute for International Health, Faculty of Medicine, University of Sydney, Sydney, NSW, Australia
    J Am Coll Cardiol 52:1817-25. 2008
    ..We propose that upgrading primary health care services is a central requirement for the control of the CVD epidemics facing the developing world...
  25. pmc Verbal autopsy coding: are multiple coders better than one?
    Rohina Joshi
    The George Institute for International Health, University of Sydney, Sydney, Australia
    Bull World Health Organ 87:51-7. 2009
    ..To assess the impact on the reported cause-of-death patterns of a verbal autopsy coding strategy based on a review of every death by multiple coders versus a single coder...
  26. ncbi request reprint Plasma lipids predict myocardial infarction, but not stroke, in patients with established cerebrovascular disease
    Anushka Patel
    The George Institute for International Health, University of Sydney, PO Box M201, Missenden Road, Sydney, NSW 2050, Australia
    Eur Heart J 26:1910-5. 2005
    ..To evaluate the role of plasma lipids in recurrent vascular events, including stroke, among individuals with established cerebrovascular disease...
  27. doi request reprint Monitoring initial response to Angiotensin-converting enzyme inhibitor-based regimens: an individual patient data meta-analysis from randomized, placebo-controlled trials
    Katy J L Bell
    Screening and Test Evaluation Program, School of Public Health, Edward Ford Building A27, University of Sydney, NSW 2006, Australia
    Hypertension 56:533-9. 2010
    ..Instead of monitoring an individual's blood pressure response, a better approach may be to simply assume the mean treatment effect...
  28. ncbi request reprint The burden of blood pressure-related disease: a neglected priority for global health
    Vlado Perkovic
    George Institute for International Health, University of Sydney, Royal Prince Alfred Hospital, NSW, Australia
    Hypertension 50:991-7. 2007
  29. pmc Safety and efficacy of routine postoperative ibuprofen for pain and disability related to ectopic bone formation after hip replacement surgery (HIPAID): randomised controlled trial
    Marlene Fransen
    The George Institute for International Health, University of Sydney, Australia
    BMJ 333:519. 2006
    ..To determine the benefits and risks of a non-steroidal anti-inflammatory drug (NSAID) as prophylaxis for ectopic bone formation in patients undergoing total hip replacement (or revision) surgery...
  30. doi request reprint Rationale and design of the Rural Andhra Pradesh Cardiovascular Prevention Study (RAPCAPS): a factorial, cluster-randomized trial of 2 practical cardiovascular disease prevention strategies developed for rural Andhra Pradesh, India
    Clara K Chow
    The George Institute for International Health, University of Sydney, Sydney, Australia
    Am Heart J 158:349-55. 2009
    ..This study aimed to implement and evaluate a CVD prevention program in a rural area of India...
  31. ncbi request reprint Effects of blood pressure lowering with perindopril and indapamide therapy on dementia and cognitive decline in patients with cerebrovascular disease
    Christophe Tzourio
    PROGRESS Collaborative Group c o Institute for International Health, University of Sydney, PO Box 576, Newtown, Sydney, NSW 2042, Australia
    Arch Intern Med 163:1069-75. 2003
    ..This study aimed to determine whether blood pressure lowering would reduce the risks of dementia and cognitive decline among individuals with cerebrovascular disease...
  32. ncbi request reprint Perindopril-based blood pressure lowering in individuals with cerebrovascular disease: consistency of benefits by age, sex and region
    Anthony Rodgers
    Clinical Trials Research Unit, University of Auckland, New Zealand
    J Hypertens 22:653-9. 2004
    ..To assess the consistency of the benefits of blood pressure lowering on secondary stroke risk by age, sex and geographic region of recruitment...
  33. ncbi request reprint Effects of the vasopeptidase inhibitor, omapatrilat, in 723 patients with coronary heart disease
    Bruce Neal
    Institute for International Health, Newtown, NSW, 2042, Australia
    J Renin Angiotensin Aldosterone Syst 3:270-6. 2002
    ....
  34. ncbi request reprint International Society of Hypertension (ISH): statement on blood pressure lowering and stroke prevention
    John Chalmers
    J Hypertens 21:651-63. 2003
    ..The meeting was conducted under the auspice of the Austin Hospital Medical Research Foundation, Melbourne...
  35. ncbi request reprint Blood pressure and the global burden of disease 2000. Part 1: estimates of blood pressure levels
    Carlene M M Lawes
    Clinical Trials Research Unit, University of Auckland, Auckland, New Zealand
    J Hypertens 24:413-22. 2006
    ..To provide global estimates of blood pressure by age and sex for adults aged > or = 30 years, by WHO subregion...
  36. ncbi request reprint Blood pressure and the global burden of disease 2000. Part II: estimates of attributable burden
    Carlene M M Lawes
    Clinical Trials Research Unit, University of Auckland, Auckland, New Zealand
    J Hypertens 24:423-30. 2006
    ..To provide estimates of the global burden of disease attributable to non-optimal blood pressure by age and sex for adults aged > or = 30 years, by WHO subregion...
  37. ncbi request reprint Dose-dependent effects of folic acid on plasma homocysteine in a randomized trial conducted among 723 individuals with coronary heart disease
    Bruce Neal
    Eur Heart J 23:1509-15. 2002
    ..2 mg dose. Fortification of foods with folic acid should result in population-wide lower levels of homocysteine but high-dose pharmacological supplementation would produce greater reductions for high-risk individuals...
  38. ncbi request reprint Does capture-recapture analysis provide more reliable estimates of the incidence and prevalence of leg ulcers in the community?
    Natalie K Walker
    Department of Medicine, University of Auckland, New Zealand
    Aust N Z J Public Health 26:451-5. 2002
    ..To determine whether capture-recapture analysis provides more reliable estimates of the cumulative incidence and prevalence of leg ulcers in Auckland, New Zealand...
  39. ncbi request reprint Leg ulcers in New Zealand: age at onset, recurrence and provision of care in an urban population
    Natalie Walker
    Clinical Trials Research Unit, University of Auckland
    N Z Med J 115:286-9. 2002
    ..To describe the age at onset, recurrence rate, and provision of care for people with leg ulcers in New Zealand...
  40. ncbi request reprint The occurrence of leg ulcers in Auckland: results of a population-based study
    Natalie Walker
    Department of Medicine, University of Auckland
    N Z Med J 115:159-62. 2002
    ..To estimate the cumulative incidence rate and prevalence of leg ulcers in Auckland...
  41. ncbi request reprint Is body mass index a risk factor for motor vehicle driver injury? A cohort study with prospective and retrospective outcomes
    Gary Whitlock
    Clinical Trials Research Unit, University of Auckland, New Zealand
    Int J Epidemiol 32:147-9. 2003
    ..To investigate the association between risk of motor vehicle driver injury and body mass index (BMI)...
  42. ncbi request reprint Incidence of heterotopic bone formation after major hip surgery
    Bruce Neal
    Institute for International Health, University of Sydney, New South Wales, Australia
    ANZ J Surg 72:808-21. 2002
    ..Heterotopic bone formation is a well-established complication of major hip surgery, but traditional reviews of the published literature may have underestimated its frequency...
  43. ncbi request reprint The ACE gene I/D polymorphism is not associated with the blood pressure and cardiovascular benefits of ACE inhibition
    Stephen B Harrap
    Department of Physiology, University of Melbourne, Melbourne, Australia
    Hypertension 42:297-303. 2003
    ..This study provides no evidence that in patients with cerebrovascular disease, knowledge of ACE genotype is useful for predicting either the risk of disease or the benefits of perindopril-based blood pressure-lowering treatment...
  44. ncbi request reprint Leg ulceration as a long-term complication of deep vein thrombosis
    Natalie Walker
    Clinical Trials Research Unit, Department of Medicine, University of Auckland, PB 92019, Auckland, New Zealand
    J Vasc Surg 38:1331-5. 2003
    ..To evaluate the role of deep vein thrombosis as a cause of leg ulcers...
  45. ncbi request reprint Leg ulceration and perceived health: a population based case-control study
    Andrew Jull
    Clinical Trials Research Unit, University of Auckland
    Age Ageing 33:236-41. 2004
    ..To quantify the effect of leg ulceration on health-related quality of life and to estimate a health state value for leg ulceration...
  46. ncbi request reprint International collaborative study of cardiovascular disease in Asia: design, rationale, and preliminary results
    Jiang He
    Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, 1430 Tulane Avenue SL 18, New Orleans, LA 70112 2073, USA
    Ethn Dis 14:260-8. 2004
    ....
  47. ncbi request reprint Effects of blood pressure lowering on cerebral white matter hyperintensities in patients with stroke: the PROGRESS (Perindopril Protection Against Recurrent Stroke Study) Magnetic Resonance Imaging Substudy
    Carole Dufouil
    INSERM U708, Paris, France
    Circulation 112:1644-50. 2005
    ..We report here the results of an MRI substudy of PROGRESS (Perindopril Protection Against Recurrent Stroke Study), a randomized trial of blood pressure lowering in subjects with cerebrovascular disease...
  48. doi request reprint Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes
    Anushka Patel
    N Engl J Med 358:2560-72. 2008
    ..In patients with type 2 diabetes, the effects of intensive glucose control on vascular outcomes remain uncertain...
  49. doi request reprint Increasing prevalence and low awareness, treatment and control of diabetes mellitus among Chinese adults: the InterASIA study
    Dongsheng Hu
    Department of Epidemiology, College of Public Health, Zhengzhou University, Zhengzhou, Henan, China
    Diabetes Res Clin Pract 81:250-7. 2008
    ..To estimate the prevalence rates of impaired fasting glucose (IFG) and diabetes mellitus (DM) and to evaluate the awareness, treatment, and control of DM in the Chinese adult population...
  50. doi request reprint Retinal vascular lesions in patients of Caucasian and Asian origin with type 2 diabetes: baseline results from the ADVANCE Retinal Measurements (AdRem) study
    Ronald P Stolk
    Department of Epidemiology, University Medical Center Groningen, P O Box 30 001, 9700RB Groningen, The Netherlands
    Diabetes Care 31:708-13. 2008
    ....