Elgene Lim

Summary

Affiliation: The Walter and Eliza Hall Institute of Medical Research
Country: Australia

Publications

  1. ncbi Desmoplastic melanoma: comparison of expression of differentiation antigens and cancer testis antigens
    Elgene Lim
    Ludwig Institute for Cancer Research Department of Medical Oncology, Austin Health, Heidelberg, Victoria, Australia
    Melanoma Res 16:347-55. 2006
  2. pmc Transcriptome analyses of mouse and human mammary cell subpopulations reveal multiple conserved genes and pathways
    Elgene Lim
    The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, VIC 3052, Australia
    Breast Cancer Res 12:R21. 2010
  3. pmc ROAST: rotation gene set tests for complex microarray experiments
    Di Wu
    The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Victoria, Australia
    Bioinformatics 26:2176-82. 2010
  4. doi Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers
    Elgene Lim
    The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia
    Nat Med 15:907-13. 2009
  5. pmc Sensitization of BCL-2-expressing breast tumors to chemotherapy by the BH3 mimetic ABT-737
    Samantha R Oakes
    The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia
    Proc Natl Acad Sci U S A 109:2766-71. 2012

Collaborators

Detail Information

Publications5

  1. ncbi Desmoplastic melanoma: comparison of expression of differentiation antigens and cancer testis antigens
    Elgene Lim
    Ludwig Institute for Cancer Research Department of Medical Oncology, Austin Health, Heidelberg, Victoria, Australia
    Melanoma Res 16:347-55. 2006
    ..Low levels of expression of cancer testis antigen may indicate that they are suboptimal targets for vaccine development in desmoplastic melanoma...
  2. pmc Transcriptome analyses of mouse and human mammary cell subpopulations reveal multiple conserved genes and pathways
    Elgene Lim
    The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, VIC 3052, Australia
    Breast Cancer Res 12:R21. 2010
    ..The epithelial cell signatures were used to interrogate mouse models of mammary tumorigenesis and to compare with their normal human counterpart subsets to identify conserved genes and networks...
  3. pmc ROAST: rotation gene set tests for complex microarray experiments
    Di Wu
    The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Victoria, Australia
    Bioinformatics 26:2176-82. 2010
    ..Methods that rely on permutation of probes unrealistically assume independence of genes, while those that rely on permutation of sample are suitable only for two-group comparisons with a good number of replicates in each group...
  4. doi Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers
    Elgene Lim
    The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia
    Nat Med 15:907-13. 2009
    ..Our findings suggest that an aberrant luminal progenitor population is a target for transformation in BRCA1-associated basal tumors ...
  5. pmc Sensitization of BCL-2-expressing breast tumors to chemotherapy by the BH3 mimetic ABT-737
    Samantha R Oakes
    The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia
    Proc Natl Acad Sci U S A 109:2766-71. 2012
    ..Our findings provide in vivo evidence that BH3 mimetics can be used to sensitize primary breast tumors to chemotherapy and further suggest that elevated BCL-2 expression constitutes a predictive response marker in breast cancer...