Danielle L Krebs

Summary

Affiliation: The Walter and Eliza Hall Institute of Medical Research
Country: Australia

Publications

  1. ncbi request reprint SOCS proteins: negative regulators of cytokine signaling
    D L Krebs
    The Walter and Eliza Hall Institute of Medical Research and the Cooperative Research Center for Cellular Growth Factors, Royal Melbourne Hospital, Victoria, Australia
    Stem Cells 19:378-87. 2001
  2. ncbi request reprint SOCS: physiological suppressors of cytokine signaling
    D L Krebs
    The Walter and Eliza Hall Institute of Medical Research and the Cooperative Research Center for Cellular Growth Factors, Post Office, Royal Melbourne Hospital, Victoria 3050, Australia
    J Cell Sci 113:2813-9. 2000
  3. pmc SOCS-6 binds to insulin receptor substrate 4, and mice lacking the SOCS-6 gene exhibit mild growth retardation
    Danielle L Krebs
    The Walter and Eliza Hall Institute of Medical Research and the Cooperative Research Centre for Cellular Growth Factors, Royal Melbourne Hospital, Victoria 3050, Australia
    Mol Cell Biol 22:4567-78. 2002
  4. ncbi request reprint A new role for SOCS in insulin action. Suppressor of cytokine signaling
    Danielle L Krebs
    The Walter and Eliza Hall Institute of Medical Research, Post Office Royal Melbourne Hospital, Victoria, Australia
    Sci STKE 2003:PE6. 2003
  5. ncbi request reprint The comparative roles of suppressor of cytokine signaling-1 and -3 in the inhibition and desensitization of cytokine signaling
    Samuel Wormald
    Division of Cancer and Haematology, The Walter and Eliza Hall Institute of Medicial Research, Parkville, Victoria, Australia
    J Biol Chem 281:11135-43. 2006
  6. pmc Development of hydrocephalus in mice lacking SOCS7
    Danielle L Krebs
    The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Victoria 3050, Australia
    Proc Natl Acad Sci U S A 101:15446-51. 2004
  7. ncbi request reprint SOCS3 negatively regulates IL-6 signaling in vivo
    Ben A Croker
    Cancer and Haematology Division, The Walter and Eliza Hall Institute of Medical Research and the Cooperative Research Centre for Cellular Growth Factors, 1G Royal Parade, Parkville, Victoria 3050, Australia
    Nat Immunol 4:540-5. 2003
  8. pmc Agm1/Pgm3-mediated sugar nucleotide synthesis is essential for hematopoiesis and development
    Kylie T Greig
    Division of Molecular Medicine, The Walter and Eliza Hall Institute of Medical Research, Victoria, Australia
    Mol Cell Biol 27:5849-59. 2007
  9. pmc A mutation in the translation initiation codon of Gata-1 disrupts megakaryocyte maturation and causes thrombocytopenia
    Ian J Majewski
    The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Victoria 3050, Australia
    Proc Natl Acad Sci U S A 103:14146-51. 2006
  10. pmc C3G regulates the size of the cerebral cortex neural precursor population
    Anne K Voss
    The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia
    EMBO J 25:3652-63. 2006

Collaborators

Detail Information

Publications11

  1. ncbi request reprint SOCS proteins: negative regulators of cytokine signaling
    D L Krebs
    The Walter and Eliza Hall Institute of Medical Research and the Cooperative Research Center for Cellular Growth Factors, Royal Melbourne Hospital, Victoria, Australia
    Stem Cells 19:378-87. 2001
    ..Additionally, the study of embryos lacking socs3 has revealed that SOCS3 is an important regulator of fetal liver hematopoiesis. The biological role of other SOCS proteins remains to be determined...
  2. ncbi request reprint SOCS: physiological suppressors of cytokine signaling
    D L Krebs
    The Walter and Eliza Hall Institute of Medical Research and the Cooperative Research Center for Cellular Growth Factors, Post Office, Royal Melbourne Hospital, Victoria 3050, Australia
    J Cell Sci 113:2813-9. 2000
    ..Thus, the use of gene targeting has confirmed that SOCS proteins regulate cytokine signaling in a physiological setting...
  3. pmc SOCS-6 binds to insulin receptor substrate 4, and mice lacking the SOCS-6 gene exhibit mild growth retardation
    Danielle L Krebs
    The Walter and Eliza Hall Institute of Medical Research and the Cooperative Research Centre for Cellular Growth Factors, Royal Melbourne Hospital, Victoria 3050, Australia
    Mol Cell Biol 22:4567-78. 2002
    ..However, both male and female SOCS-6(-/-) mice weighed approximately 10% less than wild-type littermates...
  4. ncbi request reprint A new role for SOCS in insulin action. Suppressor of cytokine signaling
    Danielle L Krebs
    The Walter and Eliza Hall Institute of Medical Research, Post Office Royal Melbourne Hospital, Victoria, Australia
    Sci STKE 2003:PE6. 2003
    ....
  5. ncbi request reprint The comparative roles of suppressor of cytokine signaling-1 and -3 in the inhibition and desensitization of cytokine signaling
    Samuel Wormald
    Division of Cancer and Haematology, The Walter and Eliza Hall Institute of Medicial Research, Parkville, Victoria, Australia
    J Biol Chem 281:11135-43. 2006
    ....
  6. pmc Development of hydrocephalus in mice lacking SOCS7
    Danielle L Krebs
    The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Victoria 3050, Australia
    Proc Natl Acad Sci U S A 101:15446-51. 2004
    ..In situ hybridization studies revealed prominent expression of Socs7 in the brain, suggestive of an important functional role of SOCS7 in this organ...
  7. ncbi request reprint SOCS3 negatively regulates IL-6 signaling in vivo
    Ben A Croker
    Cancer and Haematology Division, The Walter and Eliza Hall Institute of Medical Research and the Cooperative Research Centre for Cellular Growth Factors, 1G Royal Parade, Parkville, Victoria 3050, Australia
    Nat Immunol 4:540-5. 2003
    ..Our data indicate that SOCS3 and SOCS1 have reciprocal functions in IL-6 and IFN-gamma regulation and imply that SOCS3 has a role in preventing IFN-gamma-like responses in cells stimulated by IL-6...
  8. pmc Agm1/Pgm3-mediated sugar nucleotide synthesis is essential for hematopoiesis and development
    Kylie T Greig
    Division of Molecular Medicine, The Walter and Eliza Hall Institute of Medical Research, Victoria, Australia
    Mol Cell Biol 27:5849-59. 2007
    ....
  9. pmc A mutation in the translation initiation codon of Gata-1 disrupts megakaryocyte maturation and causes thrombocytopenia
    Ian J Majewski
    The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Victoria 3050, Australia
    Proc Natl Acad Sci U S A 103:14146-51. 2006
    ..Although the equivalent mutation to Gata-1Plt13 in humans results in production of GATA-1s, a short protein isoform initiated from a start codon downstream of the mutated initiation codon, Gata-1s was not detected in Gata-1Plt13/+ mice...
  10. pmc C3G regulates the size of the cerebral cortex neural precursor population
    Anne K Voss
    The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia
    EMBO J 25:3652-63. 2006
    ..Our results show that the size of the cortical neural precursor population is controlled by C3G-mediated inhibition of the Ras signalling pathway...
  11. ncbi request reprint The PSF.p54nrb complex is a novel Mnk substrate that binds the mRNA for tumor necrosis factor alpha
    Maria Buxade
    Division of Molecular Physiology, College of Life Sciences, University of Dundee, Dundee, UK
    J Biol Chem 283:57-65. 2008
    ..These findings identify a novel Mnk substrate. They also suggest that the Mnk-catalyzed phosphorylation of PSF may regulate the fate of specific mRNAs by modulating their binding to PSF.p54(nrb)...