Rachel R Huxley

Summary

Affiliation: The George Institute for International Health
Country: Australia

Publications

  1. pmc Excess risk of fatal coronary heart disease associated with diabetes in men and women: meta-analysis of 37 prospective cohort studies
    Rachel Huxley
    George Institute for International Health, University of Sydney, PO Box M201, Sydney, NSW 2050, Australia
    BMJ 332:73-8. 2006
  2. ncbi request reprint Does sex matter in the associations between classic risk factors and fatal coronary heart disease in populations from the Asia-Pacific region?
    Rachel Huxley
    The George Institute for International Health, University of Sydney, NSW, Australia
    J Womens Health (Larchmt) 14:820-8. 2005
  3. doi request reprint The impact of dietary and lifestyle risk factors on risk of colorectal cancer: a quantitative overview of the epidemiological evidence
    Rachel R Huxley
    The George Institute for International Health, University of Sydney, Sydney, Australia
    Int J Cancer 125:171-80. 2009
  4. ncbi request reprint Ethnic comparisons of obesity in the Asia-Pacific region: protocol for a collaborative overview of cross-sectional studies
    Rachel Huxley
    The George Institute for International Health, University of Sydney, Sydney, NSW 2050, Australia
    Obes Rev 6:193-8. 2005
  5. pmc Type-II diabetes and pancreatic cancer: a meta-analysis of 36 studies
    R Huxley
    The George Institute for International Health, The University of Sydney, PO Box M201, Missenden Road, Sydney NSW 2050, Australia
    Br J Cancer 92:2076-83. 2005
  6. ncbi request reprint Birth weight and subsequent cholesterol levels: exploration of the "fetal origins" hypothesis
    Rachel Huxley
    The George Institute, University of Sydney, Royal Prince Alfred Hospital, Camperdown, Sydney, NSW, Australia
    JAMA 292:2755-64. 2004
  7. ncbi request reprint Is birth weight a risk factor for ischemic heart disease in later life?
    Rachel Huxley
    George Institute, University of Sydney, Sydney, Australia
    Am J Clin Nutr 85:1244-50. 2007
  8. doi request reprint The metabolic syndrome identifies a heterogeneous group of metabolic component combinations in the Asia-Pacific region
    Crystal Man Ying Lee
    The George Institute for International Health, University of Sydney, Sydney, NSW 2050, Australia
    Diabetes Res Clin Pract 81:377-80. 2008
  9. doi request reprint Diabetes, body mass index and the excess risk of coronary heart disease, ischemic and hemorrhagic stroke in the Asia Pacific Cohort Studies Collaboration
    Yoshitaka Murakami
    The George Institute for Global Health, University of Sydney, Sydney, Australia
    Prev Med 54:38-41. 2012
  10. doi request reprint Adult height and the risks of cardiovascular disease and major causes of death in the Asia-Pacific region: 21,000 deaths in 510,000 men and women
    Crystal Man Ying Lee
    The George Institute for International Health, University of Sydney, Sydney, NSW, Australia
    Int J Epidemiol 38:1060-71. 2009

Detail Information

Publications39

  1. pmc Excess risk of fatal coronary heart disease associated with diabetes in men and women: meta-analysis of 37 prospective cohort studies
    Rachel Huxley
    George Institute for International Health, University of Sydney, PO Box M201, Sydney, NSW 2050, Australia
    BMJ 332:73-8. 2006
    ..To estimate the relative risk for fatal coronary heart disease associated with diabetes in men and women...
  2. ncbi request reprint Does sex matter in the associations between classic risk factors and fatal coronary heart disease in populations from the Asia-Pacific region?
    Rachel Huxley
    The George Institute for International Health, University of Sydney, NSW, Australia
    J Womens Health (Larchmt) 14:820-8. 2005
    ..Previous comparative studies have generally had insufficient numbers of women to quantify such differences reliably...
  3. doi request reprint The impact of dietary and lifestyle risk factors on risk of colorectal cancer: a quantitative overview of the epidemiological evidence
    Rachel R Huxley
    The George Institute for International Health, University of Sydney, Sydney, Australia
    Int J Cancer 125:171-80. 2009
    ....
  4. ncbi request reprint Ethnic comparisons of obesity in the Asia-Pacific region: protocol for a collaborative overview of cross-sectional studies
    Rachel Huxley
    The George Institute for International Health, University of Sydney, Sydney, NSW 2050, Australia
    Obes Rev 6:193-8. 2005
    ..It will also provide a strong evidence base upon which to define ethnic-specific cut-points for overweight and obesity...
  5. pmc Type-II diabetes and pancreatic cancer: a meta-analysis of 36 studies
    R Huxley
    The George Institute for International Health, The University of Sydney, PO Box M201, Missenden Road, Sydney NSW 2050, Australia
    Br J Cancer 92:2076-83. 2005
    ..1 vs 1.5; P=0.005). These results support a modest causal association between type-II diabetes and pancreatic cancer...
  6. ncbi request reprint Birth weight and subsequent cholesterol levels: exploration of the "fetal origins" hypothesis
    Rachel Huxley
    The George Institute, University of Sydney, Royal Prince Alfred Hospital, Camperdown, Sydney, NSW, Australia
    JAMA 292:2755-64. 2004
    ..Inverse associations between birth weight and subsequent blood cholesterol levels have been used to support the "fetal origins" hypothesis of the relevance of fetal nutrition to adult disease...
  7. ncbi request reprint Is birth weight a risk factor for ischemic heart disease in later life?
    Rachel Huxley
    George Institute, University of Sydney, Sydney, Australia
    Am J Clin Nutr 85:1244-50. 2007
    ..An inverse association between birth weight and ischemic heart disease (IHD) has been seen in observational studies...
  8. doi request reprint The metabolic syndrome identifies a heterogeneous group of metabolic component combinations in the Asia-Pacific region
    Crystal Man Ying Lee
    The George Institute for International Health, University of Sydney, Sydney, NSW 2050, Australia
    Diabetes Res Clin Pract 81:377-80. 2008
    ..To compare the prevalence of metabolic syndrome (MetS) by combinations of MetS components derived from the National Cholesterol Education Program Adult Treatment Panel III (ATPIII) and International Diabetes Federation (IDF) definitions...
  9. doi request reprint Diabetes, body mass index and the excess risk of coronary heart disease, ischemic and hemorrhagic stroke in the Asia Pacific Cohort Studies Collaboration
    Yoshitaka Murakami
    The George Institute for Global Health, University of Sydney, Sydney, Australia
    Prev Med 54:38-41. 2012
    ..To examine the effects of diabetes on coronary heart disease, ischemic and hemorrhagic stroke and cardiovascular disease according to category of body mass index...
  10. doi request reprint Adult height and the risks of cardiovascular disease and major causes of death in the Asia-Pacific region: 21,000 deaths in 510,000 men and women
    Crystal Man Ying Lee
    The George Institute for International Health, University of Sydney, Sydney, NSW, Australia
    Int J Epidemiol 38:1060-71. 2009
    ..We sought to determine the sex- and region-specific associations between height and cardiovascular outcomes, and deaths due to cancer, respiratory and injury in populations from the Asia-Pacific region...
  11. doi request reprint Comparison of waist-to-hip ratio and other obesity indices as predictors of cardiovascular disease risk in people with type-2 diabetes: a prospective cohort study from ADVANCE
    Sebastien Czernichow
    The George Institute for International Health, The University of Sydney, New South Wales, Australia
    Eur J Cardiovasc Prev Rehabil 18:312-9. 2011
    ....
  12. doi request reprint Indices of abdominal obesity are better discriminators of cardiovascular risk factors than BMI: a meta-analysis
    Crystal Man Ying Lee
    Nutrition and Lifestyle Division, The George Institute for International Health, University of Sydney, PO Box M 201, Missenden Road, Sydney NSW 2050, Australia
    J Clin Epidemiol 61:646-53. 2008
    ..To determine which simple index of overweight and obesity is the best discriminator of cardiovascular risk factors...
  13. doi request reprint Comparisons of metabolic syndrome definitions in four populations of the Asia-Pacific region
    Crystal Man Ying Lee
    The George Institute for International Health, University of Sydney, Sydney, Australia
    Metab Syndr Relat Disord 6:37-46. 2008
    ..To compare the prevalence of metabolic syndrome (MetS) by four MetS definitions in four Asia-Pacific populations, and to compare the prevalence of individual metabolic components...
  14. doi request reprint The risk of upper aero digestive tract cancer associated with smoking, with and without concurrent alcohol consumption
    Alireza Ansary-Moghaddam
    George Institute for International Health, New South Wales, Australia
    Mt Sinai J Med 76:392-403. 2009
    ..Smoking and alcohol are major causal factors for upper aerodigestive tract cancer, but reliable quantification of the combined impact of smoking and alcohol on this cancer and its major subtypes has not been performed...
  15. ncbi request reprint Prevalence of diabetes mellitus and population attributable fractions for coronary heart disease and stroke mortality in the WHO South-East Asia and Western Pacific regions
    Crystal Man Ying Lee
    The George Institute for International Health, PO Box M 201, Missenden Road, Sydney, NSW 2050, Australia
    Asia Pac J Clin Nutr 16:187-92. 2007
    ..Accurate estimates of the prevalence of diabetes are of great importance and standard methods are needed for periodic surveillance across the Asia-Pacific region and elsewhere...
  16. pmc The fraction of ischaemic heart disease and stroke attributable to smoking in the WHO Western Pacific and South-East Asian regions
    A L C Martiniuk
    The George Institute for International Health, PO Box M201, Missenden Road, Camperdown, NSW, 2050, Australia
    Tob Control 15:181-8. 2006
    ..Tobacco will soon be the biggest cause of death worldwide, with the greatest burden being borne by low and middle-income countries where 8/10 smokers now live...
  17. ncbi request reprint Does maternal nutrition in pregnancy and birth weight influence levels of CHD risk factors in adult life?
    Rachel R Huxley
    Institute for International Health, University of Sydney, New South Wales, Australia
    Br J Nutr 91:459-68. 2004
    ..Results from the present study provide no evidence to support the hypothesis that birth weight or maternal nutrition in pregnancy are associated with CHD risk factors in adult life...
  18. doi request reprint Cigarette smoking, systolic blood pressure, and cardiovascular diseases in the Asia-Pacific region
    Koshi Nakamura
    Nutrition and Lifestyle Division, The George Institute for International Health, PO Box M201, Missenden Road, Camperdown, NSW 2050, Australia
    Stroke 39:1694-702. 2008
    ..If these 2 risk factors have a synergistic impact on cardiovascular events, lowering BP and quitting smoking will contribute more to reducing CVD than would be expected from ignoring their interaction...
  19. pmc Sociodemographic correlates of the increasing trend in prevalence of gestational diabetes mellitus in a large population of women between 1995 and 2005
    Vibeke Anna
    The George Institute for International Health and School of Public Health, University of Sydney, Sydney, Australia
    Diabetes Care 31:2288-93. 2008
    ..To better identify women at risk of developing GDM we examined sociodemographic correlates and changes in the prevalence of GDM among all births between 1995 and 2005 in Australia's largest state...
  20. ncbi request reprint Impact of smoking and smoking cessation on lung cancer mortality in the Asia-Pacific region
    R Huxley
    Nutrition and Lifestyle Division, The George Institute for International Health, University of Sydney, Sydney, New South Wales, Australia
    Am J Epidemiol 165:1280-6. 2007
    ..These results suggest that tobacco control policies in Asia should not solely concentrate on preventing the uptake of smoking but also attend to cessation...
  21. doi request reprint Comparison of the Sex-Specific Associations Between Systolic Blood Pressure and the Risk of Cardiovascular Disease: A Systematic Review and Meta-analysis of 124 Cohort Studies, Including 1.2 Million Individuals
    Sanne A E Peters
    From The George Institute for Global Health, University of Sydney, Sydney, Australia S A E P, R R H, M W Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, The Netherlands S A E P Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN R R H and Department of Epidemiology, Johns Hopkins University, Baltimore, MD M W
    Stroke 44:2394-401. 2013
    ..We performed a systematic review with meta-analysis to compare reliably sex-specific associations between SBP and cardiovascular risk...
  22. ncbi request reprint Protein, programming and plumpness: is there a link?
    Rachel R Huxley
    Heart and Vascular Division, Institute for International Health, University of Sydney, 144 Burren Street, Newtown, Sydney, NSW 2042, Australia
    Clin Sci (Lond) 106:113-4. 2004
    ....
  23. doi request reprint Association of smoking and smoking cessation with major causes of mortality in the Asia Pacific Region: the Asia Pacific Cohort Studies Collaboration
    F Barzi
    The George Institute for International Health, PO Box M201, Missenden Road, Sydney, NSW 2050, Australia
    Tob Control 17:166-72. 2008
    ..We investigated the associations between smoking (including ex-smoking) and major causes of mortality in Asian men and women, and compared with Australians and New Zealanders (ANZ)...
  24. doi request reprint Blood pressure is a major risk factor for renal death: an analysis of 560 352 participants from the Asia-Pacific region
    Conall M O'Seaghdha
    George Institute for International Health, Royal Prince Alfred Hospital, Missenden Road, Camperdown, Sydney, New South Wales 2050, Australia
    Hypertension 54:509-15. 2009
    ..10). The results were similar for cohorts in Asia and Australia. These results suggest that primary prevention strategies for renal disease should focus on individuals with elevated blood pressure, diabetes mellitus, and dyslipidemia...
  25. doi request reprint Ethnic comparisons of the cross-sectional relationships between measures of body size with diabetes and hypertension
    R Huxley
    The George Institute for International Health, Sydney, NSW, Australia
    Obes Rev 9:53-61. 2008
    ....
  26. ncbi request reprint Cohort profile: the Asia Pacific Cohort Studies Collaboration
    M Woodward
    The George Institute, University of Sydney, Australia
    Int J Epidemiol 35:1412-6. 2006
  27. doi request reprint Elevated total cholesterol: its prevalence and population attributable fraction for mortality from coronary heart disease and ischaemic stroke in the Asia-Pacific region
    Mark Woodward
    The George Institute for International Health, University of Sydney, Australia
    Eur J Cardiovasc Prev Rehabil 15:397-401. 2008
    ..About half of the world's cases of cardiovascular disease occur in the Asia-Pacific region. The contribution of serum total cholesterol (TC) to this burden is poorly quantified...
  28. ncbi request reprint Obesity and risk of colorectal cancer: a meta-analysis of 31 studies with 70,000 events
    Alireza Ansary Moghaddam
    The George Institute for International Health, Sydney, Australia
    Cancer Epidemiol Biomarkers Prev 16:2533-47. 2007
    ..Previous reviews have suggested that obesity may be associated with 30% to 60% greater risk of colorectal cancer, but little consideration was given to the possible effect of publication bias on the reported association...
  29. ncbi request reprint Commentary: Modifying body weight not birthweight is the key to lowering blood pressure
    Rachel Huxley
    Institute for International Health, 144 Burren Street, Newtown, Sydney, NSW 2042, Australia
    Int J Epidemiol 31:1051-3. 2002
  30. ncbi request reprint Fatal flaw in the fetal argument
    Rachel Huxley
    The George Institute University of Sydney, NSW, Australia
    Br J Nutr 95:441-2. 2006
  31. ncbi request reprint The effect of modifiable risk factors on pancreatic cancer mortality in populations of the Asia-Pacific region
    Alireza Ansary-Moghaddam
    The George Institute, University of Sydney, Australia
    Cancer Epidemiol Biomarkers Prev 15:2435-40. 2006
    ..Known risk factors are smoking and type 2 diabetes. It remains to be seen whether these risk factors are equally important in Asia and whether other modifiable risk factors have important associations with pancreatic cancer...
  32. ncbi request reprint The role of lifestyle risk factors on mortality from colorectal cancer in populations of the Asia-Pacific region
    Rachel Huxley
    Asia Pacific Cohort Studies Collaboration Secretariat, The George Institute for International Health, Sydney, NSW, Australia
    Asian Pac J Cancer Prev 8:191-8. 2007
    ..Understanding such mechanisms could provide opportunities for novel preventive and therapeutic intervention...
  33. ncbi request reprint The impact of modifiable risk factors on mortality from prostate cancer in populations of the Asia-Pacific region
    Rachel Huxley
    Asia Pacific Cohort Studies Collaboration Secretariat, The George Institute for International Health, Sydney, NSW, Australia
    Asian Pac J Cancer Prev 8:199-205. 2007
    ..77 (0.56 - 1.05). Body size is an apparently important determinant of prostate cancer in the Asia-Pacific. Evidence of an adverse effect of smoking is conclusive only in the predominantly Caucasian parts of the region...
  34. ncbi request reprint Waist circumference thresholds provide an accurate and widely applicable method for the discrimination of diabetes
    Rachel Huxley
    Diabetes Care 30:3116-8. 2007
  35. ncbi request reprint The burden of blood pressure-related disease: a neglected priority for global health
    Vlado Perkovic
    George Institute for International Health, University of Sydney, Royal Prince Alfred Hospital, NSW, Australia
    Hypertension 50:991-7. 2007
  36. ncbi request reprint Associations between high-density lipoprotein cholesterol and both stroke and coronary heart disease in the Asia Pacific region
    Mark Woodward
    Eur Heart J 28:2653-60. 2007
    ..The inverse relationship between high-density lipoprotein (HDL) cholesterol and coronary heart disease (CHD) is well established. Questions remain about the association between HDL cholesterol and stroke, particularly for stroke subtypes...
  37. ncbi request reprint Cholesterol, coronary heart disease and stroke: a review of published evidence from observational studies and randomized controlled trials
    Rachel Huxley
    Department of Public Health Sciences, University of Oxford, Oxford, England
    Semin Vasc Med 2:315-23. 2002
    ..8 mmol/l (that is by 10 to 15%), with four fifths of this reduction being in LDL cholesterol...
  38. ncbi request reprint International Society of Hypertension (ISH): statement on blood pressure lowering and stroke prevention
    John Chalmers
    J Hypertens 21:651-63. 2003
    ..The meeting was conducted under the auspice of the Austin Hospital Medical Research Foundation, Melbourne...
  39. ncbi request reprint Unravelling the fetal origins hypothesis: is there really an inverse association between birthweight and subsequent blood pressure?
    Rachel Huxley
    Institute of Health Sciences, University of Oxford, Oxford, UK
    Lancet 360:659-65. 2002
    ..It had been estimated that a 1 kg higher birthweight is typically associated with a 2-4 mm Hg lower systolic blood pressure...