Research Topics
| Rachel R HuxleySummaryAffiliation: The George Institute for International Health Country: Australia Publications
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Detail Information
Publications
Is birth weight a risk factor for ischemic heart disease in later life?Rachel Huxley
George Institute, University of Sydney, Sydney, Australia
Am J Clin Nutr 85:1244-50. 2007..An inverse association between birth weight and ischemic heart disease (IHD) has been seen in observational studies...
The impact of dietary and lifestyle risk factors on risk of colorectal cancer: a quantitative overview of the epidemiological evidenceRachel R Huxley
The George Institute for International Health, University of Sydney, Sydney, Australia
Int J Cancer 125:171-80. 2009....
Excess risk of fatal coronary heart disease associated with diabetes in men and women: meta-analysis of 37 prospective cohort studiesRachel Huxley
George Institute for International Health, University of Sydney, PO Box M201, Sydney, NSW 2050, Australia
BMJ 332:73-8. 2006..To estimate the relative risk for fatal coronary heart disease associated with diabetes in men and women...- Does sex matter in the associations between classic risk factors and fatal coronary heart disease in populations from the Asia-Pacific region?Rachel Huxley
The George Institute for International Health, University of Sydney, NSW, Australia
J Womens Health (Larchmt) 14:820-8. 2005..Previous comparative studies have generally had insufficient numbers of women to quantify such differences reliably... - Birth weight and subsequent cholesterol levels: exploration of the "fetal origins" hypothesisRachel Huxley
The George Institute, University of Sydney, Royal Prince Alfred Hospital, Camperdown, Sydney, NSW, Australia
JAMA 292:2755-64. 2004..Inverse associations between birth weight and subsequent blood cholesterol levels have been used to support the "fetal origins" hypothesis of the relevance of fetal nutrition to adult disease... - Type-II diabetes and pancreatic cancer: a meta-analysis of 36 studiesR Huxley
The George Institute for International Health, The University of Sydney, PO Box M201, Missenden Road, Sydney NSW 2050, Australia
Br J Cancer 92:2076-83. 2005..1 vs 1.5; P=0.005). These results support a modest causal association between type-II diabetes and pancreatic cancer... - Ethnic comparisons of obesity in the Asia-Pacific region: protocol for a collaborative overview of cross-sectional studiesRachel Huxley
The George Institute for International Health, University of Sydney, Sydney, NSW 2050, Australia
Obes Rev 6:193-8. 2005..It will also provide a strong evidence base upon which to define ethnic-specific cut-points for overweight and obesity... - The metabolic syndrome identifies a heterogeneous group of metabolic component combinations in the Asia-Pacific regionCrystal Man Ying Lee
The George Institute for International Health, University of Sydney, Sydney, NSW 2050, Australia
Diabetes Res Clin Pract 81:377-80. 2008..To compare the prevalence of metabolic syndrome (MetS) by combinations of MetS components derived from the National Cholesterol Education Program Adult Treatment Panel III (ATPIII) and International Diabetes Federation (IDF) definitions... - Diabetes, body mass index and the excess risk of coronary heart disease, ischemic and hemorrhagic stroke in the Asia Pacific Cohort Studies CollaborationYoshitaka Murakami
The George Institute for Global Health, University of Sydney, Sydney, Australia
Prev Med 54:38-41. 2012..To examine the effects of diabetes on coronary heart disease, ischemic and hemorrhagic stroke and cardiovascular disease according to category of body mass index... - Adult height and the risks of cardiovascular disease and major causes of death in the Asia-Pacific region: 21,000 deaths in 510,000 men and womenCrystal Man Ying Lee
The George Institute for International Health, University of Sydney, Sydney, NSW, Australia
Int J Epidemiol 38:1060-71. 2009..We sought to determine the sex- and region-specific associations between height and cardiovascular outcomes, and deaths due to cancer, respiratory and injury in populations from the Asia-Pacific region... - Comparison of waist-to-hip ratio and other obesity indices as predictors of cardiovascular disease risk in people with type-2 diabetes: a prospective cohort study from ADVANCESebastien Czernichow
The George Institute for International Health, The University of Sydney, New South Wales, Australia
Eur J Cardiovasc Prev Rehabil 18:312-9. 2011.... - Indices of abdominal obesity are better discriminators of cardiovascular risk factors than BMI: a meta-analysisCrystal Man Ying Lee
Nutrition and Lifestyle Division, The George Institute for International Health, University of Sydney, PO Box M 201, Missenden Road, Sydney NSW 2050, Australia
J Clin Epidemiol 61:646-53. 2008..To determine which simple index of overweight and obesity is the best discriminator of cardiovascular risk factors... - The risk of upper aero digestive tract cancer associated with smoking, with and without concurrent alcohol consumptionAlireza Ansary-Moghaddam
George Institute for International Health, New South Wales, Australia
Mt Sinai J Med 76:392-403. 2009..Smoking and alcohol are major causal factors for upper aerodigestive tract cancer, but reliable quantification of the combined impact of smoking and alcohol on this cancer and its major subtypes has not been performed... - Prevalence of diabetes mellitus and population attributable fractions for coronary heart disease and stroke mortality in the WHO South-East Asia and Western Pacific regionsCrystal Man Ying Lee
The George Institute for International Health, PO Box M 201, Missenden Road, Sydney, NSW 2050, Australia
Asia Pac J Clin Nutr 16:187-92. 2007..Accurate estimates of the prevalence of diabetes are of great importance and standard methods are needed for periodic surveillance across the Asia-Pacific region and elsewhere... - Comparisons of metabolic syndrome definitions in four populations of the Asia-Pacific regionCrystal Man Ying Lee
The George Institute for International Health, University of Sydney, Sydney, Australia
Metab Syndr Relat Disord 6:37-46. 2008..To compare the prevalence of metabolic syndrome (MetS) by four MetS definitions in four Asia-Pacific populations, and to compare the prevalence of individual metabolic components... - The fraction of ischaemic heart disease and stroke attributable to smoking in the WHO Western Pacific and South-East Asian regionsA L C Martiniuk
The George Institute for International Health, PO Box M201, Missenden Road, Camperdown, NSW, 2050, Australia
Tob Control 15:181-8. 2006..Tobacco will soon be the biggest cause of death worldwide, with the greatest burden being borne by low and middle-income countries where 8/10 smokers now live... - Does maternal nutrition in pregnancy and birth weight influence levels of CHD risk factors in adult life?Rachel R Huxley
Institute for International Health, University of Sydney, New South Wales, Australia
Br J Nutr 91:459-68. 2004..Results from the present study provide no evidence to support the hypothesis that birth weight or maternal nutrition in pregnancy are associated with CHD risk factors in adult life... - Cigarette smoking, systolic blood pressure, and cardiovascular diseases in the Asia-Pacific regionKoshi Nakamura
Nutrition and Lifestyle Division, The George Institute for International Health, PO Box M201, Missenden Road, Camperdown, NSW 2050, Australia
Stroke 39:1694-702. 2008..If these 2 risk factors have a synergistic impact on cardiovascular events, lowering BP and quitting smoking will contribute more to reducing CVD than would be expected from ignoring their interaction... - Sociodemographic correlates of the increasing trend in prevalence of gestational diabetes mellitus in a large population of women between 1995 and 2005Vibeke Anna
The George Institute for International Health and School of Public Health, University of Sydney, Sydney, Australia
Diabetes Care 31:2288-93. 2008..To better identify women at risk of developing GDM we examined sociodemographic correlates and changes in the prevalence of GDM among all births between 1995 and 2005 in Australia's largest state... - Impact of smoking and smoking cessation on lung cancer mortality in the Asia-Pacific regionR Huxley
Nutrition and Lifestyle Division, The George Institute for International Health, University of Sydney, Sydney, New South Wales, Australia
Am J Epidemiol 165:1280-6. 2007..These results suggest that tobacco control policies in Asia should not solely concentrate on preventing the uptake of smoking but also attend to cessation... - Protein, programming and plumpness: is there a link?Rachel R Huxley
Heart and Vascular Division, Institute for International Health, University of Sydney, 144 Burren Street, Newtown, Sydney, NSW 2042, Australia
Clin Sci (Lond) 106:113-4. 2004.... - Association of smoking and smoking cessation with major causes of mortality in the Asia Pacific Region: the Asia Pacific Cohort Studies CollaborationF Barzi
The George Institute for International Health, PO Box M201, Missenden Road, Sydney, NSW 2050, Australia
Tob Control 17:166-72. 2008..We investigated the associations between smoking (including ex-smoking) and major causes of mortality in Asian men and women, and compared with Australians and New Zealanders (ANZ)... - Blood pressure is a major risk factor for renal death: an analysis of 560 352 participants from the Asia-Pacific regionConall M O'Seaghdha
George Institute for International Health, Royal Prince Alfred Hospital, Missenden Road, Camperdown, Sydney, New South Wales 2050, Australia
Hypertension 54:509-15. 2009..10). The results were similar for cohorts in Asia and Australia. These results suggest that primary prevention strategies for renal disease should focus on individuals with elevated blood pressure, diabetes mellitus, and dyslipidemia... - Ethnic comparisons of the cross-sectional relationships between measures of body size with diabetes and hypertensionR Huxley
The George Institute for International Health, Sydney, NSW, Australia
Obes Rev 9:53-61. 2008.... - Cohort profile: the Asia Pacific Cohort Studies CollaborationM Woodward
The George Institute, University of Sydney, Australia
Int J Epidemiol 35:1412-6. 2006 - Elevated total cholesterol: its prevalence and population attributable fraction for mortality from coronary heart disease and ischaemic stroke in the Asia-Pacific regionMark Woodward
The George Institute for International Health, University of Sydney, Australia
Eur J Cardiovasc Prev Rehabil 15:397-401. 2008..About half of the world's cases of cardiovascular disease occur in the Asia-Pacific region. The contribution of serum total cholesterol (TC) to this burden is poorly quantified... - Obesity and risk of colorectal cancer: a meta-analysis of 31 studies with 70,000 eventsAlireza Ansary Moghaddam
The George Institute for International Health, Sydney, Australia
Cancer Epidemiol Biomarkers Prev 16:2533-47. 2007..Previous reviews have suggested that obesity may be associated with 30% to 60% greater risk of colorectal cancer, but little consideration was given to the possible effect of publication bias on the reported association... - Commentary: Modifying body weight not birthweight is the key to lowering blood pressureRachel Huxley
Institute for International Health, 144 Burren Street, Newtown, Sydney, NSW 2042, Australia
Int J Epidemiol 31:1051-3. 2002 - Fatal flaw in the fetal argumentRachel Huxley
The George Institute University of Sydney, NSW, Australia
Br J Nutr 95:441-2. 2006 - The effect of modifiable risk factors on pancreatic cancer mortality in populations of the Asia-Pacific regionAlireza Ansary-Moghaddam
The George Institute, University of Sydney, Australia
Cancer Epidemiol Biomarkers Prev 15:2435-40. 2006..Activities to prevent them can be expected to lead to a major reduction in the number of deaths from this cancer, particularly in Asia with its enormous population... - The role of lifestyle risk factors on mortality from colorectal cancer in populations of the Asia-Pacific regionRachel Huxley
Asia Pacific Cohort Studies Collaboration Secretariat, The George Institute for International Health, Sydney, NSW, Australia
Asian Pac J Cancer Prev 8:191-8. 2007..Understanding such mechanisms could provide opportunities for novel preventive and therapeutic intervention... - The impact of modifiable risk factors on mortality from prostate cancer in populations of the Asia-Pacific regionRachel Huxley
Asia Pacific Cohort Studies Collaboration Secretariat, The George Institute for International Health, Sydney, NSW, Australia
Asian Pac J Cancer Prev 8:199-205. 2007..77 (0.56 - 1.05). Body size is an apparently important determinant of prostate cancer in the Asia-Pacific. Evidence of an adverse effect of smoking is conclusive only in the predominantly Caucasian parts of the region... - Waist circumference thresholds provide an accurate and widely applicable method for the discrimination of diabetesRachel Huxley
Diabetes Care 30:3116-8. 2007 - The burden of blood pressure-related disease: a neglected priority for global healthVlado Perkovic
George Institute for International Health, University of Sydney, Royal Prince Alfred Hospital, NSW, Australia
Hypertension 50:991-7. 2007 - Associations between high-density lipoprotein cholesterol and both stroke and coronary heart disease in the Asia Pacific regionMark Woodward
Eur Heart J 28:2653-60. 2007..The inverse relationship between high-density lipoprotein (HDL) cholesterol and coronary heart disease (CHD) is well established. Questions remain about the association between HDL cholesterol and stroke, particularly for stroke subtypes... - Cholesterol, coronary heart disease and stroke: a review of published evidence from observational studies and randomized controlled trialsRachel Huxley
Department of Public Health Sciences, University of Oxford, Oxford, England
Semin Vasc Med 2:315-23. 2002..8 mmol/l (that is by 10 to 15%), with four fifths of this reduction being in LDL cholesterol... - International Society of Hypertension (ISH): statement on blood pressure lowering and stroke preventionJohn Chalmers
J Hypertens 21:651-63. 2003..The meeting was conducted under the auspice of the Austin Hospital Medical Research Foundation, Melbourne... - Unravelling the fetal origins hypothesis: is there really an inverse association between birthweight and subsequent blood pressure?Rachel Huxley
Institute of Health Sciences, University of Oxford, Oxford, UK
Lancet 360:659-65. 2002..It had been estimated that a 1 kg higher birthweight is typically associated with a 2-4 mm Hg lower systolic blood pressure...