Rachel Huxley

Summary

Affiliation: The George Institute for International Health
Country: Australia

Publications

  1. ncbi request reprint Ethnic comparisons of the cross-sectional relationships between measures of body size with diabetes and hypertension
    R Huxley
    The George Institute for International Health, Sydney, NSW, Australia
    Obes Rev 9:53-61. 2008
  2. ncbi request reprint The impact of modifiable risk factors on mortality from prostate cancer in populations of the Asia-Pacific region
    Rachel Huxley
    Asia Pacific Cohort Studies Collaboration Secretariat, The George Institute for International Health, Sydney, NSW, Australia
    Asian Pac J Cancer Prev 8:199-205. 2007
  3. doi request reprint Body mass index, waist circumference and waist:hip ratio as predictors of cardiovascular risk--a review of the literature
    R Huxley
    Renal and Metabolic Division, The George Institute for International Health, The University of Sydney, Sydney, Australia
    Eur J Clin Nutr 64:16-22. 2010
  4. ncbi request reprint The role of lifestyle risk factors on mortality from colorectal cancer in populations of the Asia-Pacific region
    Rachel Huxley
    Asia Pacific Cohort Studies Collaboration Secretariat, The George Institute for International Health, Sydney, NSW, Australia
    Asian Pac J Cancer Prev 8:191-8. 2007
  5. ncbi request reprint Impact of smoking and smoking cessation on lung cancer mortality in the Asia-Pacific region
    R Huxley
    Nutrition and Lifestyle Division, The George Institute for International Health, University of Sydney, Sydney, New South Wales, Australia
    Am J Epidemiol 165:1280-6. 2007
  6. ncbi request reprint Coffee, decaffeinated coffee, and tea consumption in relation to incident type 2 diabetes mellitus: a systematic review with meta-analysis
    Rachel Huxley
    The George Institute for International Health, The University of Sydney, Australia
    Arch Intern Med 169:2053-63. 2009
  7. doi request reprint Smoking, diabetes and cardiovascular diseases in men in the Asia Pacific region
    Andre Pascal Kengne
    The George Institute for International Health, The University of Sydney, NSW, Australia
    J Diabetes 1:173-81. 2009
  8. ncbi request reprint Ethnic comparisons of obesity in the Asia-Pacific region: protocol for a collaborative overview of cross-sectional studies
    Rachel Huxley
    The George Institute for International Health, University of Sydney, Sydney, NSW 2050, Australia
    Obes Rev 6:193-8. 2005
  9. doi request reprint Blood pressure is a major risk factor for renal death: an analysis of 560 352 participants from the Asia-Pacific region
    Conall M O'Seaghdha
    George Institute for International Health, Royal Prince Alfred Hospital, Missenden Road, Camperdown, Sydney, New South Wales 2050, Australia
    Hypertension 54:509-15. 2009
  10. pmc Impact of blood pressure lowering on cardiovascular outcomes in normal weight, overweight, and obese individuals: the Perindopril Protection Against Recurrent Stroke Study trial
    Sebastien Czernichow
    George Institute for International Health, University of Sydney, Sydney, Australia
    Hypertension 55:1193-8. 2010

Collaborators

Detail Information

Publications44

  1. ncbi request reprint Ethnic comparisons of the cross-sectional relationships between measures of body size with diabetes and hypertension
    R Huxley
    The George Institute for International Health, Sydney, NSW, Australia
    Obes Rev 9:53-61. 2008
    ....
  2. ncbi request reprint The impact of modifiable risk factors on mortality from prostate cancer in populations of the Asia-Pacific region
    Rachel Huxley
    Asia Pacific Cohort Studies Collaboration Secretariat, The George Institute for International Health, Sydney, NSW, Australia
    Asian Pac J Cancer Prev 8:199-205. 2007
    ..77 (0.56 - 1.05). Body size is an apparently important determinant of prostate cancer in the Asia-Pacific. Evidence of an adverse effect of smoking is conclusive only in the predominantly Caucasian parts of the region...
  3. doi request reprint Body mass index, waist circumference and waist:hip ratio as predictors of cardiovascular risk--a review of the literature
    R Huxley
    Renal and Metabolic Division, The George Institute for International Health, The University of Sydney, Sydney, Australia
    Eur J Clin Nutr 64:16-22. 2010
    ..associated with cardiovascular risk? (2) Which of the anthropometric measures is a better discriminator of risk? and (3) Are there any notable differences in the strength and nature of these associations across diverse ethnic groups?..
  4. ncbi request reprint The role of lifestyle risk factors on mortality from colorectal cancer in populations of the Asia-Pacific region
    Rachel Huxley
    Asia Pacific Cohort Studies Collaboration Secretariat, The George Institute for International Health, Sydney, NSW, Australia
    Asian Pac J Cancer Prev 8:191-8. 2007
    ..Understanding such mechanisms could provide opportunities for novel preventive and therapeutic intervention...
  5. ncbi request reprint Impact of smoking and smoking cessation on lung cancer mortality in the Asia-Pacific region
    R Huxley
    Nutrition and Lifestyle Division, The George Institute for International Health, University of Sydney, Sydney, New South Wales, Australia
    Am J Epidemiol 165:1280-6. 2007
    ..These results suggest that tobacco control policies in Asia should not solely concentrate on preventing the uptake of smoking but also attend to cessation...
  6. ncbi request reprint Coffee, decaffeinated coffee, and tea consumption in relation to incident type 2 diabetes mellitus: a systematic review with meta-analysis
    Rachel Huxley
    The George Institute for International Health, The University of Sydney, Australia
    Arch Intern Med 169:2053-63. 2009
    ..Similar associations have also been reported for decaffeinated coffee and tea. We report herein the findings of meta-analyses for the association between coffee, decaffeinated coffee, and tea consumption with risk of diabetes...
  7. doi request reprint Smoking, diabetes and cardiovascular diseases in men in the Asia Pacific region
    Andre Pascal Kengne
    The George Institute for International Health, The University of Sydney, NSW, Australia
    J Diabetes 1:173-81. 2009
    ..To assess whether there is a statistical interaction between smoking and diabetes that is related to the risk of cardiovascular disease (CVD) in men in the Asia Pacific region...
  8. ncbi request reprint Ethnic comparisons of obesity in the Asia-Pacific region: protocol for a collaborative overview of cross-sectional studies
    Rachel Huxley
    The George Institute for International Health, University of Sydney, Sydney, NSW 2050, Australia
    Obes Rev 6:193-8. 2005
    ..It will also provide a strong evidence base upon which to define ethnic-specific cut-points for overweight and obesity...
  9. doi request reprint Blood pressure is a major risk factor for renal death: an analysis of 560 352 participants from the Asia-Pacific region
    Conall M O'Seaghdha
    George Institute for International Health, Royal Prince Alfred Hospital, Missenden Road, Camperdown, Sydney, New South Wales 2050, Australia
    Hypertension 54:509-15. 2009
    ..10). The results were similar for cohorts in Asia and Australia. These results suggest that primary prevention strategies for renal disease should focus on individuals with elevated blood pressure, diabetes mellitus, and dyslipidemia...
  10. pmc Impact of blood pressure lowering on cardiovascular outcomes in normal weight, overweight, and obese individuals: the Perindopril Protection Against Recurrent Stroke Study trial
    Sebastien Czernichow
    George Institute for International Health, University of Sydney, Sydney, Australia
    Hypertension 55:1193-8. 2010
    ..However, the greater baseline level of cardiovascular risk in those with higher body mass index meant that these patients obtained the greatest benefit...
  11. ncbi request reprint Does sex matter in the associations between classic risk factors and fatal coronary heart disease in populations from the Asia-Pacific region?
    Rachel Huxley
    The George Institute for International Health, University of Sydney, NSW, Australia
    J Womens Health (Larchmt) 14:820-8. 2005
    ..Previous comparative studies have generally had insufficient numbers of women to quantify such differences reliably...
  12. doi request reprint The effects of blood pressure reduction and of different blood pressure-lowering regimens on major cardiovascular events according to baseline blood pressure: meta-analysis of randomized trials
    Sebastien Czernichow
    The George Institute, Sydney, Australia
    J Hypertens 29:4-16. 2011
    ..The objective was to compare the risk reductions achieved by different blood pressure-lowering regimens among individuals with different baseline blood pressures...
  13. doi request reprint Does body mass index impact on the relationship between systolic blood pressure and cardiovascular disease?: meta-analysis of 419 488 individuals from the Asia pacific cohort studies collaboration
    Rumi Tsukinoki
    Professorial Unit, The George Institute for Global Health, University of Sydney, PO Box M201, Missenden Road, NSW 2050, Australia
    Stroke 43:1478-83. 2012
    ..Elevated blood pressure and excess body mass index (BMI) are established risk factors for cardiovascular disease (CVD) but controversy exists as to whether, and how, they interact...
  14. ncbi request reprint Blood pressure variables and cardiovascular risk: new findings from ADVANCE
    Andre Pascal Kengne
    ADVANCE Collaborative Group, The George Institute for International Health, PO Box M201, Missenden Road, Sydney NSW 2050, Australia
    Hypertension 54:399-404. 2009
    ..However, SBP may be the simplest and most useful predictor across a wider range of age groups and populations...
  15. ncbi request reprint Cigarette smoking, systolic blood pressure, and cardiovascular diseases in the Asia-Pacific region
    Koshi Nakamura
    Nutrition and Lifestyle Division, The George Institute for International Health, PO Box M201, Missenden Road, Camperdown, NSW 2050, Australia
    Stroke 39:1694-702. 2008
    ..If these 2 risk factors have a synergistic impact on cardiovascular events, lowering BP and quitting smoking will contribute more to reducing CVD than would be expected from ignoring their interaction...
  16. pmc The relationship between proteinuria and coronary risk: a systematic review and meta-analysis
    Vlado Perkovic
    The George Institute for International Health, Sydney, New South Wales, Australia
    PLoS Med 5:e207. 2008
    ..We therefore undertook a systematic review of published cohort studies aiming to provide a reliable estimate of the strength of association between proteinuria and coronary heart disease...
  17. ncbi request reprint Elevated total cholesterol: its prevalence and population attributable fraction for mortality from coronary heart disease and ischaemic stroke in the Asia-Pacific region
    Mark Woodward
    The George Institute for International Health, University of Sydney, Australia
    Eur J Cardiovasc Prev Rehabil 15:397-401. 2008
    ..About half of the world's cases of cardiovascular disease occur in the Asia-Pacific region. The contribution of serum total cholesterol (TC) to this burden is poorly quantified...
  18. ncbi request reprint The effect of modifiable risk factors on pancreatic cancer mortality in populations of the Asia-Pacific region
    Alireza Ansary-Moghaddam
    The George Institute, University of Sydney, Australia
    Cancer Epidemiol Biomarkers Prev 15:2435-40. 2006
    ..Known risk factors are smoking and type 2 diabetes. It remains to be seen whether these risk factors are equally important in Asia and whether other modifiable risk factors have important associations with pancreatic cancer...
  19. ncbi request reprint Systematic review: sodium bicarbonate treatment regimens for the prevention of contrast-induced nephropathy
    Sophia Zoungas
    University of Sydney, Sydney, Australia
    Ann Intern Med 151:631-8. 2009
    ..Intravenous sodium bicarbonate has been proposed to reduce the risk for contrast-induced nephropathy (CIN)...
  20. ncbi request reprint Temporal trends in overweight and obesity of children and adolescents from nine Provinces in China from 1991-2006
    Zhaohui Cui
    The George Institute for International Health, University of Sydney, NSW, Australia
    Int J Pediatr Obes 5:365-74. 2010
    ..To assess temporal changes in mean body mass index (BMI) and the impact of socio-economic status on the prevalence of overweight and obesity among Chinese children and adolescents in nine provinces between 1991 and 2006...
  21. ncbi request reprint Obesity and risk of colorectal cancer: a meta-analysis of 31 studies with 70,000 events
    Alireza Ansary Moghaddam
    The George Institute for International Health, Sydney, Australia
    Cancer Epidemiol Biomarkers Prev 16:2533-47. 2007
    ..Previous reviews have suggested that obesity may be associated with 30% to 60% greater risk of colorectal cancer, but little consideration was given to the possible effect of publication bias on the reported association...
  22. ncbi request reprint Is birth weight a risk factor for ischemic heart disease in later life?
    Rachel Huxley
    George Institute, University of Sydney, Sydney, Australia
    Am J Clin Nutr 85:1244-50. 2007
    ..An inverse association between birth weight and ischemic heart disease (IHD) has been seen in observational studies...
  23. ncbi request reprint The development of a national salt reduction strategy for Australia
    Jacqui Webster
    George Institute for International Health, Missenden Road, Sydney, NSW 2050, Australia
    Asia Pac J Clin Nutr 18:303-9. 2009
    ..With industry and government engagement, this promises to be a highly effective, low cost option for preventing chronic disease...
  24. ncbi request reprint Burden of lung cancer deaths due to smoking for men and women in the WHO Western Pacific and South East Asian regions
    Alexandra Martiniuk
    The George Institute for International Health, Sydney, Australia
    Asian Pac J Cancer Prev 11:67-72. 2010
    ..Eighty percent of all smokers live in low and middle-income countries of the Asia Pacific region but actual estimates of the burden of disease due to smoking in the region have yet to be quantified...
  25. ncbi request reprint The burden of blood pressure-related disease: a neglected priority for global health
    Vlado Perkovic
    George Institute for International Health, University of Sydney, Royal Prince Alfred Hospital, NSW, Australia
    Hypertension 50:991-7. 2007
  26. pmc Excess risk of fatal coronary heart disease associated with diabetes in men and women: meta-analysis of 37 prospective cohort studies
    Rachel Huxley
    George Institute for International Health, University of Sydney, PO Box M201, Sydney, NSW 2050, Australia
    BMJ 332:73-8. 2006
    ..To estimate the relative risk for fatal coronary heart disease associated with diabetes in men and women...
  27. ncbi request reprint Fatal flaw in the fetal argument
    Rachel Huxley
    The George Institute University of Sydney, NSW, Australia
    Br J Nutr 95:441-2. 2006
  28. ncbi request reprint Associations between high-density lipoprotein cholesterol and both stroke and coronary heart disease in the Asia Pacific region
    Mark Woodward
    Eur Heart J 28:2653-60. 2007
    ..The inverse relationship between high-density lipoprotein (HDL) cholesterol and coronary heart disease (CHD) is well established. Questions remain about the association between HDL cholesterol and stroke, particularly for stroke subtypes...
  29. ncbi request reprint Association of smoking and smoking cessation with major causes of mortality in the Asia Pacific Region: the Asia Pacific Cohort Studies Collaboration
    F Barzi
    The George Institute for International Health, PO Box M201, Missenden Road, Sydney, NSW 2050, Australia
    Tob Control 17:166-72. 2008
    ..We investigated the associations between smoking (including ex-smoking) and major causes of mortality in Asian men and women, and compared with Australians and New Zealanders (ANZ)...
  30. ncbi request reprint Adult height and the risks of cardiovascular disease and major causes of death in the Asia-Pacific region: 21,000 deaths in 510,000 men and women
    Crystal Man Ying Lee
    The George Institute for International Health, University of Sydney, Sydney, NSW, Australia
    Int J Epidemiol 38:1060-71. 2009
    ..We sought to determine the sex- and region-specific associations between height and cardiovascular outcomes, and deaths due to cancer, respiratory and injury in populations from the Asia-Pacific region...
  31. ncbi request reprint Cohort profile: the Asia Pacific Cohort Studies Collaboration
    M Woodward
    The George Institute, University of Sydney, Australia
    Int J Epidemiol 35:1412-6. 2006
  32. doi request reprint The effects of a reduced-sodium, high-potassium salt substitute on food taste and acceptability in rural northern China
    Nicole Li
    The George Institute for International Health, University of Sydney, PO Box M201, Camperdown, Sydney, NSW 2050, Australia
    Br J Nutr 101:1088-93. 2009
    ..Possible small differences in flavour did not importantly deter the use of the salt substitute in this study group, although the acceptability of the salt substitute by a more general population group would need to be confirmed...
  33. pmc The fraction of ischaemic heart disease and stroke attributable to smoking in the WHO Western Pacific and South-East Asian regions
    A L C Martiniuk
    The George Institute for International Health, PO Box M201, Missenden Road, Camperdown, NSW, 2050, Australia
    Tob Control 15:181-8. 2006
    ..Tobacco will soon be the biggest cause of death worldwide, with the greatest burden being borne by low and middle-income countries where 8/10 smokers now live...
  34. ncbi request reprint Commentary: Modifying body weight not birthweight is the key to lowering blood pressure
    Rachel Huxley
    Institute for International Health, 144 Burren Street, Newtown, Sydney, NSW 2042, Australia
    Int J Epidemiol 31:1051-3. 2002
  35. doi request reprint Proteinuria and stroke: a meta-analysis of cohort studies
    Toshiharu Ninomiya
    The George Institute for International Health, The University of Sydney, Sydney, Australia
    Am J Kidney Dis 53:417-25. 2009
    ..We undertook a meta-analysis of published cohort studies to provide a reliable estimate of the strength of association between proteinuria and risk of stroke...
  36. pmc Type-II diabetes and pancreatic cancer: a meta-analysis of 36 studies
    R Huxley
    The George Institute for International Health, The University of Sydney, PO Box M201, Missenden Road, Sydney NSW 2050, Australia
    Br J Cancer 92:2076-83. 2005
    ..1 vs 1.5; P=0.005). These results support a modest causal association between type-II diabetes and pancreatic cancer...
  37. ncbi request reprint The discrimination of dyslipidaemia using anthropometric measures in ethnically diverse populations of the Asia-Pacific Region: the Obesity in Asia Collaboration
    F Barzi
    The George Institute for International Health, University of Sydney, Sydney, Australia
    Obes Rev 11:127-36. 2010
    ..WHR cut-points of 0.8 for women and 0.9 for men are optimal for discriminating those individuals likely to have adverse lipid profiles and in need of further clinical assessment...
  38. ncbi request reprint Birth weight and subsequent cholesterol levels: exploration of the "fetal origins" hypothesis
    Rachel Huxley
    The George Institute, University of Sydney, Royal Prince Alfred Hospital, Camperdown, Sydney, NSW, Australia
    JAMA 292:2755-64. 2004
    ..Inverse associations between birth weight and subsequent blood cholesterol levels have been used to support the "fetal origins" hypothesis of the relevance of fetal nutrition to adult disease...
  39. ncbi request reprint Leisure-time physical activity alone may not be a sufficient public health approach to prevent obesity--a focus on China
    A Bauman
    Institute for Obesity, Nutrition and Exercise, and School of Public Health, University of Sydney, Sydney, New South Wales, Australia
    Obes Rev 9:119-26. 2008
    ..These will pose policy challenges in the developing world, if they are to be taken seriously as obesity prevention strategies...
  40. ncbi request reprint Waist circumference thresholds provide an accurate and widely applicable method for the discrimination of diabetes
    Rachel Huxley
    Diabetes Care 30:3116-8. 2007
  41. ncbi request reprint Unravelling the fetal origins hypothesis: is there really an inverse association between birthweight and subsequent blood pressure?
    Rachel Huxley
    Institute of Health Sciences, University of Oxford, Oxford, UK
    Lancet 360:659-65. 2002
    ..It had been estimated that a 1 kg higher birthweight is typically associated with a 2-4 mm Hg lower systolic blood pressure...
  42. ncbi request reprint Cholesterol, coronary heart disease and stroke: a review of published evidence from observational studies and randomized controlled trials
    Rachel Huxley
    Department of Public Health Sciences, University of Oxford, Oxford, England
    Semin Vasc Med 2:315-23. 2002
    ..8 mmol/l (that is by 10 to 15%), with four fifths of this reduction being in LDL cholesterol...
  43. ncbi request reprint International Society of Hypertension (ISH): statement on blood pressure lowering and stroke prevention
    John Chalmers
    J Hypertens 21:651-63. 2003
    ..The meeting was conducted under the auspice of the Austin Hospital Medical Research Foundation, Melbourne...