Mark A Hall

Summary

Affiliation: The Walter and Eliza Hall Institute of Medical Research
Country: Australia

Publications

  1. ncbi request reprint SCL is required for normal function of short-term repopulating hematopoietic stem cells
    David J Curtis
    Rotary Bone Marrow Research Laboratory, Royal Melbourne Hospital, Melbourne, Victoria 3050, Australia
    Blood 103:3342-8. 2004
  2. pmc The critical regulator of embryonic hematopoiesis, SCL, is vital in the adult for megakaryopoiesis, erythropoiesis, and lineage choice in CFU-S12
    Mark A Hall
    Rotary Bone Marrow Research Laboratory, Royal Melbourne Hospital, Melbourne, Victoria 3050, Australia
    Proc Natl Acad Sci U S A 100:992-7. 2003
  3. ncbi request reprint Aberrant mast-cell differentiation in mice lacking the stem-cell leukemia gene
    Jessica M Salmon
    Rotary Bone Marrow Research Laboratories, Royal Melbourne Hospital, Melbourne, Australia
    Blood 110:3573-81. 2007
  4. ncbi request reprint Genetically tagging endothelial cells in vivo: bone marrow-derived cells do not contribute to tumor endothelium
    Joachim R Gothert
    Division of Cancer Biology, Telethon Institute for Child Health Research, Centre for Child Health Research and Western Australian Institute for Medical Research, University of Western Australia, West Perth, Australia
    Blood 104:1769-77. 2004
  5. ncbi request reprint In vivo fate-tracing studies using the Scl stem cell enhancer: embryonic hematopoietic stem cells significantly contribute to adult hematopoiesis
    Joachim R Gothert
    Division of Cancer Biology, Telethon Institute for Child Health Research, Center for Child Health Research, University of Western Australia, West Perth, Australia
    Blood 105:2724-32. 2005
  6. pmc Functional but abnormal adult erythropoiesis in the absence of the stem cell leukemia gene
    Mark A Hall
    Rotary Bone Marrow Research Laboratories, P O Royal Melbourne Hospital, Grattan St, Parkville, Melbourne 3050, Australia
    Mol Cell Biol 25:6355-62. 2005
  7. ncbi request reprint The essential haematopoietic transcription factor Scl is also critical for neuronal development
    Cara K Bradley
    Telethon Institute for Child Health Research and Centre for Child Health Research at the University of Western Australia, Subiaco WA 6008, Australia
    Eur J Neurosci 23:1677-89. 2006
  8. pmc A critical role for the transcription factor Scl in platelet production during stress thrombopoiesis
    Matthew P McCormack
    Bone Marrow Research Laboratories, Royal Melbourne Hospital, Melbourne Health Research Directorate, c o Royal Melbourne Hospital Post Office, Grattan St, Parkville VIC 3050 Australia
    Blood 108:2248-56. 2006
  9. pmc Selection against PUMA gene expression in Myc-driven B-cell lymphomagenesis
    Sean P Garrison
    Department of Biochemistry, St Jude Children s Research Hospital, 332 N Lauderdale, Memphis, TN 38105, USA
    Mol Cell Biol 28:5391-402. 2008

Collaborators

Detail Information

Publications9

  1. ncbi request reprint SCL is required for normal function of short-term repopulating hematopoietic stem cells
    David J Curtis
    Rotary Bone Marrow Research Laboratory, Royal Melbourne Hospital, Melbourne, Victoria 3050, Australia
    Blood 103:3342-8. 2004
    ..Generation of SCL-deleted cells within SCL-wild-type mice rescued the early repopulating defect. Together, our results suggest that SCL is required for the normal function of short-term repopulating HSCs...
  2. pmc The critical regulator of embryonic hematopoiesis, SCL, is vital in the adult for megakaryopoiesis, erythropoiesis, and lineage choice in CFU-S12
    Mark A Hall
    Rotary Bone Marrow Research Laboratory, Royal Melbourne Hospital, Melbourne, Victoria 3050, Australia
    Proc Natl Acad Sci U S A 100:992-7. 2003
    ..These results suggest that SCL is critical for megakaryopoiesis and erythropoiesis, but is dispensable for production of myeloid cells during adult hematopoiesis...
  3. ncbi request reprint Aberrant mast-cell differentiation in mice lacking the stem-cell leukemia gene
    Jessica M Salmon
    Rotary Bone Marrow Research Laboratories, Royal Melbourne Hospital, Melbourne, Australia
    Blood 110:3573-81. 2007
    ..Together, these studies suggest that loss of SCL leads to aberrant mast-cell differentiation of megakaryocyte-erythroid progenitors...
  4. ncbi request reprint Genetically tagging endothelial cells in vivo: bone marrow-derived cells do not contribute to tumor endothelium
    Joachim R Gothert
    Division of Cancer Biology, Telethon Institute for Child Health Research, Centre for Child Health Research and Western Australian Institute for Medical Research, University of Western Australia, West Perth, Australia
    Blood 104:1769-77. 2004
    ..Thus, this genetic model strongly suggests that BM cells do not contribute to tumor endothelium and demonstrates the lineage relation between pre-existing endothelium and newly generated tumor endothelial cells...
  5. ncbi request reprint In vivo fate-tracing studies using the Scl stem cell enhancer: embryonic hematopoietic stem cells significantly contribute to adult hematopoiesis
    Joachim R Gothert
    Division of Cancer Biology, Telethon Institute for Child Health Research, Center for Child Health Research, University of Western Australia, West Perth, Australia
    Blood 105:2724-32. 2005
    ..Additionally, the HSC-SCL-Cre-ER(T) mice will provide a valuable tool to achieve temporally controlled genetic manipulation of HSCs...
  6. pmc Functional but abnormal adult erythropoiesis in the absence of the stem cell leukemia gene
    Mark A Hall
    Rotary Bone Marrow Research Laboratories, P O Royal Melbourne Hospital, Grattan St, Parkville, Melbourne 3050, Australia
    Mol Cell Biol 25:6355-62. 2005
    ....
  7. ncbi request reprint The essential haematopoietic transcription factor Scl is also critical for neuronal development
    Cara K Bradley
    Telethon Institute for Child Health Research and Centre for Child Health Research at the University of Western Australia, Subiaco WA 6008, Australia
    Eur J Neurosci 23:1677-89. 2006
    ..This finding underlines Scl's critical function in cell fate determination of mesodermal as well as neuroectodermal tissues...
  8. pmc A critical role for the transcription factor Scl in platelet production during stress thrombopoiesis
    Matthew P McCormack
    Bone Marrow Research Laboratories, Royal Melbourne Hospital, Melbourne Health Research Directorate, c o Royal Melbourne Hospital Post Office, Grattan St, Parkville VIC 3050 Australia
    Blood 108:2248-56. 2006
    ..These findings suggest that Scl acts up-stream of NF-E2 expression to control megakaryocyte development and platelet release in settings of thrombopoietic stress...
  9. pmc Selection against PUMA gene expression in Myc-driven B-cell lymphomagenesis
    Sean P Garrison
    Department of Biochemistry, St Jude Children s Research Hospital, 332 N Lauderdale, Memphis, TN 38105, USA
    Mol Cell Biol 28:5391-402. 2008
    ..These findings establish that PUMA is silenced in human malignancies, and they suggest PUMA as a target for the development of novel chemotherapeutics...