Research Topics
Species | G G GilesSummaryAffiliation: The Cancer Council Victoria Country: Australia Publications
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Detail Information
Publications
A longitudinal study of the association between dietary factors, serum lipids, and bone marrow lesions of the kneeDawn Dore
Menzies Research Institute Tasmania, University of Tasmania, Private Bag 23, Hobart, Tasmania, 7000, Australia
Arthritis Res Ther 14:R13. 2012..Bone marrow lesions (BMLs) play an important role in knee osteoarthritis, but their etiology is not well understood. The aim of this longitudinal study was to describe the association between dietary factors, serum lipids, and BMLs...- Second to fourth digit ratio (2D:4D) and concentrations of circulating sex hormones in adulthoodDavid C Muller
Cancer Epidemiology Centre, The Cancer Council of Victoria, Melbourne, Australia
Reprod Biol Endocrinol 9:57. 2011..The objective of this study was to examine whether circulating concentrations of sex hormones and SHBG measured in adulthood was associated with 2D:4D... - Contribution of large genomic BRCA1 alterations to early-onset breast cancer selected for family history and tumour morphology: a report from The Breast Cancer Family RegistryLetitia D Smith
Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne, Melbourne, Victoria 3010, Australia
Breast Cancer Res 13:R14. 2011..We sought to test the value of selecting women for BRCA1 mutation testing on the basis of family history and/or breast tumour morphology criteria as well as the value of testing for large genomic alterations in BRCA1... - Assessing interactions between the associations of common genetic susceptibility variants, reproductive history and body mass index with breast cancer risk in the breast cancer association consortium: a combined case-control studyRoger L Milne
Genetic and Molecular Epidemiology Group, Human Cancer Genetics Programme, Spanish National Cancer Research Centre CNIO, Madrid, 28029, Spain
Breast Cancer Res 12:R110. 2010.... - A PALB2 mutation associated with high risk of breast cancerMelissa C Southey
Department of Pathology, The University of Melbourne, Victoria 3010, Australia
Breast Cancer Res 12:R109. 2010..Little is known about by how much or whether risk differs by mutation or family history, owing to the paucity of studies of cases unselected for family history... 
The androgen receptor CAG repeat polymorphism and modification of breast cancer risk in BRCA1 and BRCA2 mutation carriersAmanda B Spurdle
Queensland Institute of Medical Research, Brisbane, Australia
Breast Cancer Res 7:R176-83. 2005..Women with germline BRCA1 mutations who carry at least one AR allele with 28 or more repeats have been reported to have an earlier age at onset of breast cancer...- The AIB1 glutamine repeat polymorphism is not associated with risk of breast cancer before age 40 years in Australian womenKaren G Montgomery
Cancer Genetics Laboratory, Victorian Breast Cancer Research Consortium, Peter MacCallum Cancer Centre, St, Andrews Place, East Melbourne, Victoria, Australia
Breast Cancer Res 7:R353-6. 2005..It contains a glutamine repeat (CAG/CAA) polymorphism at its carboxyl-terminal region that may alter the transcriptional activation of the receptor and affect susceptibility to breast cancer through altered sensitivity to hormones... - CYP17 genetic polymorphism, breast cancer, and breast cancer risk factors: Australian Breast Cancer Family StudyJiun Horng Chang
Centre for Genetic Epidemiology, The University of Melbourne, Victoria, Australia
Breast Cancer Res 7:R513-21. 2005..We attempted to replicate the findings of studies assessing such interactions with the -34T-->C polymorphism... - Meat consumption and risk of primary hip and knee joint replacement due to osteoarthritis: a prospective cohort studyYuanyuan Wang
Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Alfred Hospital, Melbourne, VIC 3004, Australia
BMC Musculoskelet Disord 12:17. 2011..However, whether it affects the risk of knee and hip osteoarthritis is unknown. We performed a prospective cohort study to examine the relationship between meat consumption and risk of primary hip and knee replacement for osteoarthritis... - Validation of de-identified record linkage to ascertain hospital admissions in a cohort studyAlison Beauchamp
Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia
BMC Med Res Methodol 11:42. 2011..We sought to develop and validate a method for linking a cohort study to a state-wide hospital admissions dataset with limited availability of unique identifying variables... - The 4q27 locus and prostate cancer riskElizabeth A Tindall
Cancer Genetics Group, Children s Cancer Institute Australia for Medical Research, Sydney Children s Hospital, High St, Randwick, NSW, Australia
BMC Cancer 10:69. 2010..This region harbors two cytokine genes IL-2 and the recently described IL-21... - Relationship between body adiposity measures and risk of primary knee and hip replacement for osteoarthritis: a prospective cohort studyYuanyuan Wang
Department of Epidemiology and Preventive Medicine, Monash University, Central and Eastern Clinical School, Alfred Hospital, Melbourne, VIC 3004, Australia
Arthritis Res Ther 11:R31. 2009..It is unknown whether the adipose mass and the distribution of adipose mass are associated with the risk of primary knee and hip replacement for osteoarthritis. The aim of the present investigation was to examine this in a cohort study... - Effect of antioxidants on knee cartilage and bone in healthy, middle-aged subjects: a cross-sectional studyYuanyuan Wang
Department of Epidemiology and Preventive Medicine, Monash University, Central and Eastern Clinical School, Alfred Hospital, Melbourne, VIC 3004, Australia
Arthritis Res Ther 9:R66. 2007..While our findings need to be confirmed by longitudinal studies, they highlight the potential of the diet to modify the risk of osteoarthritis... - Dietary fatty acid intake affects the risk of developing bone marrow lesions in healthy middle-aged adults without clinical knee osteoarthritis: a prospective cohort studyYuanyuan Wang
Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Alfred Hospital, Commercial Road, Melbourne, VIC 3004, Australia
Arthritis Res Ther 11:R63. 2009..The aim of this study was to examine the association between fatty acid consumption and the incidence of BMLs in healthy middle-aged adults without clinical knee OA... - Reduced rates of primary joint replacement for osteoarthritis in Italian and Greek migrants to Australia: the Melbourne Collaborative Cohort StudyYuanyuan Wang
Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Alfred Hospital, Melbourne, VIC 3004, Australia
Arthritis Res Ther 11:R86. 2009..The aim of this study was to compare the rates of primary joint replacement for osteoarthritis for Italian and Greek migrants to Australia and Australian-born individuals... - Development of bone marrow lesions is associated with adverse effects on knee cartilage while resolution is associated with improvement--a potential target for prevention of knee osteoarthritis: a longitudinal studyMiranda L Davies-Tuck
Department of Epidemiology and Preventive Medicine, Monash University, Central and Eastern Clinical School, Alfred Hospital, Melbourne, VIC 3004, Australia
Arthritis Res Ther 12:R10. 2010..To examine the relationship between development or resolution of bone marrow lesions (BMLs) and knee cartilage properties in a 2 year prospective study of asymptomatic middle-aged adults... - Vastus medialis cross-sectional area is positively associated with patella cartilage and bone volumes in a pain-free community-based populationPatricia A Berry
Department of Epidemiology and Preventive Medicine, Monash University Central and Eastern Clinical School, Melbourne, Australia
Arthritis Res Ther 10:R143. 2008..The aim of this study was to examine potential determinants of vastus medialis and lateralis cross-sectional areas and the relationship between the cross-sectional area and patella cartilage and bone volumes... 
Body size and composition and risk of postmenopausal breast cancerRobert J Macinnis
Cancer Epidemiology Centre, Cancer Control Research Institute, The Cancer Council Victoria, 1 Rathdowne Street, Carlton South, Victoria 3053, Australia
Cancer Epidemiol Biomarkers Prev 13:2117-25. 2004....- Sexual factors and prostate cancerG G Giles
Cancer Epidemiology Centre, and Centre for Behavioural Research in Cancer, The Cancer Council Victoria, Melbourne, Australia
BJU Int 92:211-6. 2003..To assess whether prostate cancer might be related to hormone levels and, by inference, to differences in sexual activity... - Dietary carbohydrate, fibre, glycaemic index, glycaemic load and the risk of postmenopausal breast cancerGraham G Giles
Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Australia
Int J Cancer 118:1843-7. 2006..43, 0.99), p = 0.005. Our data do not support a strong role for GI and GL in breast carcinogenesis but suggest that increased intake of fibre and carbohydrate may be associated with the diagnosis of cancers of more favourable prognosis... - Cancer statistics: everything you wanted to know about the cancer registry data but were too afraid to askGraham G Giles
Victorian Cancer Registry, The Cancer Council Victoria, Melbourne, Victoria, Australia
ANZ J Surg 74:931-4. 2004..To promote the use of ANZ population cancer data, the following paper describes the principal statistics that are available and identifies common problems with their use... - Early growth, adult body size and prostate cancer riskGraham G Giles
Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia
Int J Cancer 103:241-5. 2003.... - CFTR deltaF508 carrier status, risk of breast cancer before the age of 40 and histological grading in a population-based case-control studyM C Southey
Department of Pathology, Peter MacCallum Cancer Institute, Melbourne, Australia
Int J Cancer 79:487-9. 1998..A combination of our data with other large population-based samples of cases and controls is required to resolve this issue... - Population-based estimate of the average age-specific cumulative risk of breast cancer for a defined set of protein-truncating mutations in BRCA1 and BRCA2. Australian Breast Cancer Family StudyJ L Hopper
The University of Melbourne, Centre for Genetic Epidemiology, Carlton, Victoria, Australia
Cancer Epidemiol Biomarkers Prev 8:741-7. 1999..Breast cancer risk in BRCA1 or BRCA2 mutation carriers may be modified by other genetic or environmental factors. Genetic counselors may need to take into account the family history of the consultand... - Estrogen receptor polymorphism at codon 325 and risk of breast cancer in women before age fortyM C Southey
Department of Pathology and Research, Peter MacCallum Cancer Institute, Melbourne, Australia
J Natl Cancer Inst 90:532-6. 1998..28+/-0.05 versus 0.11+/-0.02; P<.001). To determine whether this polymorphism is a risk factor for early-onset breast cancer, we conducted a population-based, case-control-family study in Australia... 
Dietary intake of B vitamins and methionine and risk of lung cancerJ K Bassett
Cancer Epidemiology Centre, Cancer Council Victoria, Carlton South, Victoria, Australia
Eur J Clin Nutr 66:182-7. 2012..Disruption of one-carbon mechanism may affect cancer risk. We investigated prospectively the relationship between dietary intakes of methionine, B vitamins associated with one-carbon metabolism and risk of lung cancer...- Plasma concentration of Propionibacterium acnes antibodies and prostate cancer risk: results from an Australian population-based case-control studyG Severi
Cancer Epidemiology Centre, The Cancer Council of Victoria, Melbourne, Victoria 3053, Australia
Br J Cancer 103:411-5. 2010..The aim of our study was to test whether circulating levels of P. acnes antibodies are associated with prostate cancer risk and tumour characteristics using plasma samples from a population-based case-control study... - Smoking and prostate cancer: findings from an Australian case-control studyG G Giles
Cancer Epidemiology Centre, Anti Cancer Council of Victoria, Melbourne, Australia
Ann Oncol 12:761-5. 2001..To examine the risk of smoking on histopathologically-confirmed moderate- and high-grade prostate cancer... - Obesity and adiposity are associated with the rate of patella cartilage volume loss over 2 years in adults without knee osteoarthritisA J Teichtahl
Department of Epidemiology and Preventive Medicine, Monash University, Central and Eastern Clinical School, Alfred Hospital, Melbourne, Australia
Ann Rheum Dis 68:909-13. 2009..The aim of this study was to determine whether measures of obesity and adiposity are associated with the rate of patella cartilage volume loss in healthy adults... - Regressive logistic and proportional hazards disease models for within-family analyses of measured genotypes, with application to a CYP17 polymorphism and breast cancerJisheng S Cui
Centre for Genetic Epidemiology, The University of Melbourne, Melbourne, Victoria, Australia
Genet Epidemiol 24:161-72. 2003..This analytical approach is well-suited to the data that arise from population-based case-control-family studies, in which cases, controls and relatives are studied, and genotype is measured for some but not all subjects... - The relationship between the angle of the trochlear groove and patella cartilage and bone morphology--a cross-sectional study of healthy adultsA J Teichtahl
Department of Epidemiology and Preventive Medicine, Monash University, Central and Eastern Clinical School, Alfred Hospital, Melbourne, Victoria 3004, Australia
Osteoarthritis Cartilage 15:1158-62. 2007..This cross-sectional study investigated the relationship between the shape of the trochlear groove and patella cartilage and bone morphology in healthy adults... - Morphological predictors of BRCA1 germline mutations in young women with breast cancerM C Southey
Department of Pathology, Genetic Epidemiology Laboratory, Victoria, Carlton, Australia
Br J Cancer 104:903-9. 2011..We sought an optimal strategy for identifying carriers using family history, breast cancer morphology and hormone receptor status data... - Body size and composition and prostate cancer riskRobert J Macinnis
Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia
Cancer Epidemiol Biomarkers Prev 12:1417-21. 2003..2 (95% confidence interval, 1.2-4.1). For each 10-kg increase in fat mass, the risk ratio was 1.4 (95% confidence interval, 1.0-1.8). Energy imbalance may play a role in the development of aggressive prostate cancer... - The natural history of bone marrow lesions in community-based adults with no clinical knee osteoarthritisM L Davies-Tuck
Department of Epidemiology and Preventive Medicine, Monash University, Central and Eastern Clinical School, Alfred Hospital, Melbourne, Australia
Ann Rheum Dis 68:904-8. 2009..This study in a healthy, pain-free population aimed to examine the natural history of BML; factors associated with incidence and progression of BML over 2 years and whether incident BML are associated with the development of pain... - Increased cancer risks for relatives of very early-onset breast cancer cases with and without BRCA1 and BRCA2 mutationsG S Dite
Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Level 1, 723 Swanston Street, Melbourne, Carlton VIC 3053, Australia
Br J Cancer 103:1103-8. 2010..Little is known regarding cancer risks for relatives of women with very early-onset breast cancer... - Consumption of animal products, their nutrient components and postmenopausal circulating steroid hormone concentrationsM T Brinkman
Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Australia
Eur J Clin Nutr 64:176-83. 2010..We aimed to investigate the association between consumption of animal products and the plasma concentrations of steroid hormones and sex hormone-binding globulin (SHBG)... - Bone marrow lesions predict progression of cartilage defects and loss of cartilage volume in healthy middle-aged adults without knee pain over 2 yrsA E Wluka
Department of Epidemiology and Preventive Medicine, Monash University Medical School, Alfred Hospital, Prahran, Melbourne, Victoria 3004, Australia
Rheumatology (Oxford) 47:1392-6. 2008..In knee OA, the presence of bone marrow lesions (BMLs) predicts pain and progression of disease. Their occurrence has been described in healthy, pain-free subjects, but whether their presence affects change in cartilage is unknown... - Risks of Lynch syndrome cancers for MSH6 mutation carriersLaura Baglietto
Cancer Epidemiology Centre, Victorian Cancer Registry, Carlton, Victoria, Australia
J Natl Cancer Inst 102:193-201. 2010..Germline mutations in MSH6 account for 10%-20% of Lynch syndrome colorectal cancers caused by hereditary DNA mismatch repair gene mutations. Because there have been only a few studies of mutation carriers, their cancer risks are uncertain... - Second to fourth digit ratio (2D : 4D), breast cancer risk factors, and breast cancer risk: a prospective cohort studyD C Muller
1 Cancer Epidemiology Centre, Cancer Council Victoria, 100 Drummond Street, Carlton South, Victoria 3053, Australia 2 Centre for MEGA Epidemiology, The University of Melbourne, Melbourne, Victoria, Australia
Br J Cancer 107:1631-6. 2012..If confirmed in other studies, this suggests that lower exposure or sensitivity to prenatal testosterone might be associated with lower risk of breast cancer... - Segregation analyses of 1,476 population-based Australian families affected by prostate cancerJ Cui
Centre for Genetic Epidemiology, The University of Melbourne, Carlton, Victoria 3053, Australia
Am J Hum Genet 68:1207-18. 2001..Within discussed limitations, these analyses confirm the genetic heterogeneity, of prostate cancer susceptibility, that is becoming evident from linkage analyses, and they may aid future efforts in gene discovery... - Hormone replacement therapy and accuracy of mammographic screeningA M Kavanagh
Cancer Epidemiology Centre, Anti Cancer Council of Victoria, Australia
Lancet 355:270-4. 2000..Hormone replacement therapy (HRT) is commonly used and may affect the accuracy of mammographic screening... - Dietary patterns and risk of breast cancerL Baglietto
Cancer Epidemiology Centre, The Cancer Council Victoria, 100 Drummond Street, Carlton, Melbourne, Victoria 3053, Australia
Br J Cancer 104:524-31. 2011..Evidence is emerging that prudent/healthy dietary patterns might be associated with a reduced risk of breast cancer... - Men with colorectal cancer are predisposed to prostate cancerAndrew R Moot
Cabrini Monash University Academic Surgical Unit, Cancer Epidemiology Centre and Victorian Cancer Registry, Anti-Cancer Council of Victoria, and Cabrini Hospital, Victoria, Australia
ANZ J Surg 73:289-93. 2003..However, there is no direct evidence that screening for prostate cancer leads to a reduction in mortality. This should be considered when discussing long-term follow up... - Body size and composition and risk of rectal cancer (Australia)Robert J Macinnis
Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Carlton South, Vic, Australia
Cancer Causes Control 17:1291-7. 2006..0) were positively associated with rectal cancer risk. There was no evidence that risk differed by sex for any of the anthropometric measures. CONCLUSIONS: Waist circumference and fat mass may be weakly related to risk of rectal cancer... - Body size and composition and colon cancer risk in womenRobert J Macinnis
Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia
Int J Cancer 118:1496-500. 2006..Central adiposity appears to be associated with colon cancer risk in women... - Variants in the prostate-specific antigen (PSA) gene and prostate cancer risk, survival, and circulating PSAGianluca Severi
Cancer Epidemiology Center, The Cancer Council Victoria, Melbourne, Victoria, Australia
Cancer Epidemiol Biomarkers Prev 15:1142-7. 2006..The genotypes and haplotypes studied might be associated with the PSA gene function or be in linkage disequilibrium with other unmeasured and functional variants in the PSA or other genes... - A comparison of adiposity measures as predictors of all-cause mortality: the Melbourne Collaborative Cohort StudyJulie A Simpson
Cancer Epidemiology Centre, Council Council Victoria, and Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, University of Melbourne, Level 2 723 Swanston St, Carlton, Victoria 3053, Australia
Obesity (Silver Spring) 15:994-1003. 2007..Our goal was to examine five different measures of adiposity as predictors of all-cause mortality... - Average volume of alcohol consumed, type of beverage, drinking pattern and the risk of death from all causesLaura Baglietto
Cancer Epidemiology Centre, The Cancer Council of Victoria, Carlton VIC 3053, Melbourne, Australia
Alcohol Alcohol 41:664-71. 2006..04). CONCLUSIONS: These results confirm previous findings about the effect of average volume of alcohol and type of beverage and suggest that drinking pattern is an independent risk factor for all-cause mortality... - Familial risks, early-onset breast cancer, and BRCA1 and BRCA2 germline mutationsGillian S Dite
Centre for Genetic Epidemiology, The University of Melbourne, Melbourne, Australia
J Natl Cancer Inst 95:448-57. 2003.... - Evaluation of an FFQ for assessment of antioxidant intake using plasma biomarkers in an ethnically diverse populationAllison M Hodge
Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Australia
Public Health Nutr 12:2438-47. 2009.... - Rare mutations in XRCC2 increase the risk of breast cancerD J Park
Genetic Epidemiology Laboratory, The University of Melbourne, Victoria, Australia
Am J Hum Genet 90:734-9. 2012..This study demonstrates the power of massively parallel sequencing for discovering susceptibility genes for common, complex diseases... - The sensitivity, specificity, and positive predictive value of screening mammography and symptomatic statusA M Kavanagh
Australian Research Centre in Sex, Health and Society, La Trobe University, Melbourne, Victoria, Australia
J Med Screen 7:105-10. 2000..To examine whether the accuracy of screening mammography varies according to symptomatic status reported at the time of screening... - Second to fourth digit ratio (2D:4D) and prostate cancer risk in the Melbourne Collaborative Cohort StudyD C Muller
Cancer Epidemiology Centre, Cancer Council of Victoria, Melbourne, Victoria, Australia
Br J Cancer 105:438-40. 2011..Recent studies have reported a strong association between 2D:4D and risk of prostate cancer... - The role of SMAD4 in early-onset colorectal cancerS G Royce
Department of Pathology, University of Melbourne, Victoria, Australia
Colorectal Dis 12:213-9. 2010..Chromosomal loss within the region of 18q and loss of SMAD4 expression have been reported to be frequent somatic events during colorectal cancer tumour progression; however, their associations with age at onset have not been widely studied... - Familial patterns of covariation for cardiovascular risk factors in adults: The Victorian Family Heart StudyS B Harrap
Department of Physiology, University of Melbourne, Parkville, Victoria, Australia
Am J Epidemiol 152:704-15. 2000..On a background of genetic influences, there are periods in early life during which the family environment cements long-term correlations between adult relatives in cardiovascular risk factors... - Circulating insulin-like growth factor-I and binding protein-3 and the risk of breast cancerLaura Baglietto
Cancer Epidemiology Centre, The Cancer Council Victoria, 1 Rathdowne Street, Carlton, Melbourne, Victoria 3053, Australia
Cancer Epidemiol Biomarkers Prev 16:763-8. 2007..More prospective studies are needed to clarify the age dependence of the association between IGF-I and IGFBP-3 and breast cancer... - Uptake of offer to receive genetic information about BRCA1 and BRCA2 mutations in an Australian population-based studyLouise A Keogh
Centre for Genetic Epidemiology, University of Melbourne, 723 Swanston Street, Carlton, Victoria 3053, Australia
Cancer Epidemiol Biomarkers Prev 13:2258-63. 2004.... - Foods, nutrients and prostate cancerAllison M Hodge
Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Australia
Cancer Causes Control 15:11-20. 2004..CONCLUSIONS: Based on these findings, diets rich in olive oil (a source of oleic acid), tomatoes and allium vegetables might reduce the risk of prostate cancer... - Dietary patterns and cardiovascular mortality in the Melbourne Collaborative Cohort StudyLinton R Harriss
Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia
Am J Clin Nutr 86:221-9. 2007..Despite increased cardiovascular disease risk factors, migrants to Australia from Mediterranean countries have lower mortality than do native-born Australians. Dietary patterns may contribute to this... - Body size and composition and the risk of lymphohematopoietic malignanciesRobert J Macinnis
Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia
J Natl Cancer Inst 97:1154-7. 2005..83, 95% CI = 1.15 to 2.90; P = .01), and waist circumference (per 10-cm increase HR = 1.35, 95% CI = 1.06 to 1.72; P = .02). Lymphoproliferative malignancies and subgroups showed little relationship with body size... - Androgenetic alopecia and prostate cancer: findings from an Australian case-control studyGraham G Giles
Cancer Epidemiology Centre, Anti-Cancer Council of Victoria, Melbourne, VIC 3053 Australia
Cancer Epidemiol Biomarkers Prev 11:549-53. 2002..91 (1.59-5.32) for vertex baldness; and 1.95 (1.10-3.45) for frontal and vertex baldness. This association between the pattern of AA and prostate cancer points to shared androgen pathways that are worthy of additional investigation... - Obesity and outcomes in premenopausal and postmenopausal breast cancerSherene Loi
Peter MacCallum Cancer Centre, 723 Swanston Street, Carlton, Victoria 3053, Australia
Cancer Epidemiol Biomarkers Prev 14:1686-91. 2005..Given the high and increasing prevalence of obesity in western countries, more research on improving the treatment of obese breast cancer patients is warranted... - Associations between congenital malformations and childhood cancer. A register-based case-control studyA E Altmann
Consultative Council on Obstetric and Paediatric Mortality and Morbidity, Perinatal Data Collection Unit, Department of Human Services, Victoria, Australia
Br J Cancer 78:1244-9. 1998..The usefulness of record linkage between accurate population-based registers in the epidemiological study of disease has also been reinforced... - A positive association of smoking and articular knee joint cartilage in healthy peopleT L Racunica
Department of Epidemiology and Preventive Medicine, Monash University, Central and Eastern Clinical School, Alfred Hospital, Melbourne, Victoria 3004, Australia
Osteoarthritis Cartilage 15:587-90. 2007..To determine whether smoking affects knee cartilage in healthy adults by examining the association of tobacco use with tibial cartilage volume and tibiofemoral cartilage defects... - BRCA1 mutations and other sequence variants in a population-based sample of Australian women with breast cancerM C Southey
Department of Pathology and Research, Peter MacCallum Cancer Institute, Melbourne, Victoria, Australia
Br J Cancer 79:34-9. 1999..6%). Seven rare variants were also detected, but for none was there evidence of a strong effect on breast cancer susceptibility. Therefore, on a population basis, rare variants are likely to contribute little to breast cancer incidence... - Circulating steroid hormone concentrations in postmenopausal women in relation to body size and compositionLaura Baglietto
Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Vic, Australia
Breast Cancer Res Treat 115:171-9. 2009..This effect requires around 6 years to be detectable by way of circulating steroid hormone levels... - The rs743572 common variant in the promoter of CYP17A1 is not associated with prostate cancer risk or circulating hormonal levelsGianluca Severi
Cancer Epidemiology Centre, The Cancer Council Victoria, Carlton, Victoria 3053, Australia
BJU Int 101:492-6. 2008..To use a large population-based case-control study to test the association between the common genetic variant rs743572 (-34 T to C), prostate cancer risk and circulating levels of several hormones... - Using mammographic density to improve breast cancer screening outcomesAnne M Kavanagh
Key Centre for Women s Health in Society, School of Population Health, University of Melbourne, Melbourne, Australia
Cancer Epidemiol Biomarkers Prev 17:2818-24. 2008..There would be little additional benefit in targeting screening based on age and hormone therapy use... - The beliefs, and reported and intended behaviors of unaffected men in response to their family history of prostate cancerRuth Cowan
Department of Paediatrics, The University of Melbourne, Parkville, Victoria, Australia
Genet Med 10:430-8. 2008.... - Body size and composition and colon cancer risk in menRobert J Macinnis
Cancer Epidemiology Centre, The Cancer Council Victoria, 1 Rathdowne Street, Carlton South, Melbourne, Victoria 3053, Australia
Cancer Epidemiol Biomarkers Prev 13:553-9. 2004..CONCLUSION: Male colon cancer appears to be related to body size and composition by two different pathways, via central adiposity and via non-adipose mass... - Red meat, chicken, and fish consumption and risk of colorectal cancerDallas R English
Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia
Cancer Epidemiol Biomarkers Prev 13:1509-14. 2004..Evidence on the relationship between risk of colorectal cancer and poultry and fish consumption is inconsistent... - The effect of socioeconomic status on survival from colorectal cancer in the Melbourne Collaborative Cohort StudyHelen L Kelsall
The Cancer Council Victoria, Carlton, Victoria 3053, Australia
Soc Sci Med 68:290-7. 2009.... - Prognosis of premenopausal breast cancer and childbirth prior to diagnosisKelly-Anne Phillips
Peter MacCallum Cancer Centre, University of Melbourne, Carlton, Victoria 3053, Australia
J Clin Oncol 22:699-705. 2004..Clinicians should be aware that women diagnosed with breast cancer within a few years following childbirth may have a worse outcome than that suggested solely by the standard histopathological prognostic factors of their cancer... - Asthma, asthma medications, and prostate cancer riskGianluca Severi
Cancer Epidemiology Centre, The Cancer Council of Victoria, Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Carlton, VIC 3053, Australia
Cancer Epidemiol Biomarkers Prev 19:2318-24. 2010..The aim of this study was to assess whether a history of asthma or the use of asthma medications is associated with prostate cancer risk... - HFE Cys282Tyr homozygotes with serum ferritin concentrations below 1000 microg/L are at low risk of hemochromatosisKatrina J Allen
Murdoch Childrens Research Institute, Melbourne, Australia
Hepatology 52:925-33. 2010..These observations have implications for the management of C282Y homozygotes... - HFE C282Y homozygotes are at increased risk of breast and colorectal cancerNicholas J Osborne
Gut and Liver, Murdoch Childrens Research Institute, Melbourne, Vic, Australia
Hepatology 51:1311-8. 2010..16; 95% CI = 0.74, 1.84), or prostate cancer (HR = 1.08; 95% CI = 0.68, 1.70). Conclusion: HFE C282Y homozygotes have twice the risk of colorectal and breast cancer compared with those individuals without the C282Y variant... - Rectal cancer in Victoria in 1994: patterns of reported managementK Chip Farmer
Victorian Cancer Registry, Anti Cancer Council of Victoria, Carlton, Australia
ANZ J Surg 72:265-70. 2002..A retrospective survey of medical practitioners was conducted to describe the management of patients newly diagnosed with rectal cancer in 1994, prior to the publication of best practice guidelines... - Population-based, case-control-family design to investigate genetic and environmental influences on melanoma risk: Australian Melanoma Family StudyAnne E Cust
Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, School of Population Health, The University of Melbourne, Level 1, Melbourne, Victoria, Australia
Am J Epidemiol 170:1541-54. 2009..The authors discuss methodological and analytical issues related to the study design and conduct, as well as the potentially novel insights the study can deliver... - Dietary patterns and prostate cancer riskDavid C Muller
Cancer Epidemiology Centre, The Cancer Council of Victoria and Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Melbourne, Australia
Cancer Epidemiol Biomarkers Prev 18:3126-9. 2009..87 to 1.14 and all 95% confidence intervals included 1. The analyses by aggressiveness, Gleason score groups, and age at diagnosis did not show any association (all P(trend) > 0.07)... - Epidemiological investigation of prostate cancerGraham G Giles
Cancer Epidemiology Centre, Cancer Control Research Institute, Carlton South, Australia
Methods Mol Med 81:1-19. 2003 - Fat consumption and its association with age-related macular degenerationElaine W T Chong
Centre for Eye Research Australia, University of Melbourne, East Melbourne, Victoria, Australia
Arch Ophthalmol 127:674-80. 2009..To evaluate associations between past dietary fat intake and the prevalence of age-related macular degeneration (AMD)... - Circulating steroid hormone levels and risk of breast cancer for postmenopausal womenLaura Baglietto
Cancer Epidemiology Centre, The Cancer Council Victoria, Victoria, Melbourne, Australia
Cancer Epidemiol Biomarkers Prev 19:492-502. 2010.... - Body size, weight change, and risk of colon cancerJulie K Bassett
Cancer Epidemiology Centre, Cancer Council Victoria, Carlton, Victoria, Australia
Cancer Epidemiol Biomarkers Prev 19:2978-86. 2010..Few studies have investigated effects of weight change on colon cancer risk... - Cancer risks for mismatch repair gene mutation carriers: a population-based early onset case-family studyMark A Jenkins
Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Victoria, Australia
Clin Gastroenterol Hepatol 4:489-98. 2006..These may be overestimates, due to analytic problems, and not generalizable. We estimated average cancer risks for mutations identified in population-based early onset colorectal cancer cases (probands) unselected for family history... - A comparison of different methods for including 'age at menopause' in analyses of the association between hormone replacement therapy use and breast cancerJulie A Simpson
Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne and the Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, University of Melbourne, Melbourne, Australia
J Fam Plann Reprod Health Care 33:11-6. 2007.... - The common variant rs1447295 on chromosome 8q24 and prostate cancer risk: results from an Australian population-based case-control studyGianluca Severi
Cancer Epidemiology Centre, The Cancer Council Victoria, 1 Rathdowne Street, Carlton, Victoria 3053, Australia
Cancer Epidemiol Biomarkers Prev 16:610-2. 2007.... - Measures of familial aggregation depend on definition of family history: meta-analysis for colorectal cancerLaura Baglietto
Cancer Epidemiology Centre, The Cancer Council of Victoria, 100 Rathdowne Street, Carlton, Melbourne, Victoria 3053, Australia
J Clin Epidemiol 59:114-24. 2006.... - Plasma phospholipid fatty acid composition as a biomarker of habitual dietary fat intake in an ethnically diverse cohortAllison M Hodge
Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Australia
Nutr Metab Cardiovasc Dis 17:415-26. 2007.... - Circulating steroid hormones and the risk of prostate cancerGianluca Severi
Cancer Epidemiology Centre, The Cancer Council Victoria, University of Melbourne, Melbourne, Australia
Cancer Epidemiol Biomarkers Prev 15:86-91. 2006..06, 0.2, and 0.1, respectively). High levels of testosterone and adrenal androgens are thus associated with reduced risk of aggressive prostate cancer but not with nonaggressive disease... - Circulating insulin-like growth factor-I and binding protein-3 and risk of prostate cancerGianluca Severi
Cancer Epidemiology Centre, Cancer Council Victoria, 1 Rathdowne Street, Carlton, Victoria 3053, Australia
Cancer Epidemiol Biomarkers Prev 15:1137-41. 2006..49 (95% confidence interval, 1.11-2.00). The HRs did not differ by tumor aggressiveness or age at onset (all Ps > or = 0.4). In our study, high levels of IGFBP-3 but not IGF-I were associated with an increased risk of prostate cancer... - Dietary patterns and diabetes incidence in the Melbourne Collaborative Cohort StudyAllison M Hodge
Cancer Epidemiology Centre, The Cancer Council Victoria, 1 Rathdowne Street, Carlton, Victoria 3053, Australia
Am J Epidemiol 165:603-10. 2007..Avoidance of a dietary pattern including meats and fatty foods, as well as adherence to a pattern including salad and cooked vegetables, is recommended... - Alcohol consumption and prostate cancer risk: results from the Melbourne collaborative cohort studyLaura Baglietto
Cancer Epidemiology Centre, Cancer Council of Victoria, Melbourne, Vic, Australia
Int J Cancer 119:1501-4. 2006..Our results show that alcohol consumption does not influence overall prostate cancer incidence but we found suggestive evidence that alcohol consumption might decrease the incidence of aggressive prostate cancer and mortality... - Glycemic index and dietary fiber and the risk of type 2 diabetesAllison M Hodge
Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Australia
Diabetes Care 27:2701-6. 2004..To examine associations between type 2 diabetes and fiber, glycemic load (GL), dietary glycemic index (GI), and fiber-rich foods... - Does dietary folate intake modify effect of alcohol consumption on breast cancer risk? Prospective cohort studyLaura Baglietto
Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, 100 Drummond Street, Carlton, Victoria 3053, Australia
BMJ 331:807. 2005..To evaluate the effect of dietary folate intake on the relation between alcohol consumption and breast cancer risk... - Is cancer risk associated with anger control and negative affect? Findings from a prospective cohort studyVictoria M White
Centre for Behavioural Research in Cancer, The Cancer Council Victoria, 1 Rathdowne Street, Carlton VIC 3053, Australia
Psychosom Med 69:667-74. 2007..To examine the associations between anger control and negative affect and the risk of five common cancers and total cancers. Possible associations between emotional states and the risk of cancer have long been postulated... - Increased diabetes incidence in Greek and Italian migrants to Australia: how much can be explained by known risk factors?Allison M Hodge
Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Australia
Diabetes Care 27:2330-4. 2004.... - Plasma phospholipid and dietary fatty acids as predictors of type 2 diabetes: interpreting the role of linoleic acidAllison M Hodge
Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Australia
Am J Clin Nutr 86:189-97. 2007..Dietary fatty acids may be associated with diabetes but are difficult to measure accurately... - A protein-truncating mutation in CYP17A1 in three sisters with early-onset breast cancerJohn L Hopper
Centre for Genetic Epidemiology, The University of Melbourne, Carlton, Victoria, Australia
Hum Mutat 26:298-302. 2005.... - The Melbourne Collaborative Cohort StudyG G Giles
Cancer Epidemiology Centre, Cancer Control Research Institute, Anti-Cancer Council of Victoria, Melbourne, Australia
IARC Sci Publ 156:69-70. 2002 - Alcohol intake, consumption pattern and beverage type, and the risk of Type 2 diabetesA M Hodge
Cancer Epidemiology Centre, The Cancer Council Victoria, Carlton, Australia
Diabet Med 23:690-7. 2006..To examine associations between amount and frequency of alcohol consumption, and Type 2 diabetes... - Insulin resistance as a major determinant of increased coronary heart disease risk in postmenopausal women with Type 2 diabetes mellitusR M Stoney
Nutrition Department, Alfred Hospital, Melbourne, Australia
Diabet Med 18:476-82. 2001..Therapeutic approaches that increase insulin sensitivity may serve to reduce CHD risk in this vulnerable group. Diabet. Med. 18, 476-482 (2001)..