G G Giles

Summary

Affiliation: The Cancer Council Victoria
Country: Australia

Publications

  1. ncbi request reprint Detection of infectious organisms in archival prostate cancer tissues
    Melissa A Yow
    Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, VIC 3004, Australia
    BMC Cancer 14:579. 2014
  2. pmc The relationship between retinal vessel calibre and knee cartilage and BMLs
    Miranda L Davies-Tuck
    Department of Epidemiology and Preventive Medicine, Monash University, Central and Eastern Clinical School, Alfred Hospital, Melbourne, Vic, 3004, Australia
    BMC Musculoskelet Disord 13:255. 2012
  3. pmc Analysis of Xq27-28 linkage in the international consortium for prostate cancer genetics (ICPCG) families
    Joan E Bailey-Wilson
    Inherited Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Baltimore, MD 21224, USA
    BMC Med Genet 13:46. 2012
  4. pmc The use of DNA from archival dried blood spots with the Infinium HumanMethylation450 array
    Jihoon E Joo
    Genetic Epidemiology Laboratory, Department of Pathology, The University of Melbourne, Victoria, 3010, Australia
    BMC Biotechnol 13:23. 2013
  5. pmc A longitudinal study of the association between dietary factors, serum lipids, and bone marrow lesions of the knee
    Dawn Dore
    Menzies Research Institute Tasmania, University of Tasmania, Private Bag 23, Hobart, Tasmania, 7000, Australia
    Arthritis Res Ther 14:R13. 2012
  6. pmc Second to fourth digit ratio (2D:4D) and concentrations of circulating sex hormones in adulthood
    David C Muller
    Cancer Epidemiology Centre, The Cancer Council of Victoria, Melbourne, Australia
    Reprod Biol Endocrinol 9:57. 2011
  7. pmc Contribution of large genomic BRCA1 alterations to early-onset breast cancer selected for family history and tumour morphology: a report from The Breast Cancer Family Registry
    Letitia D Smith
    Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne, Melbourne, Victoria 3010, Australia
    Breast Cancer Res 13:R14. 2011
  8. pmc Assessing interactions between the associations of common genetic susceptibility variants, reproductive history and body mass index with breast cancer risk in the breast cancer association consortium: a combined case-control study
    Roger L Milne
    Genetic and Molecular Epidemiology Group, Human Cancer Genetics Programme, Spanish National Cancer Research Centre CNIO, Madrid, 28029, Spain
    Breast Cancer Res 12:R110. 2010
  9. pmc A PALB2 mutation associated with high risk of breast cancer
    Melissa C Southey
    Department of Pathology, The University of Melbourne, Victoria 3010, Australia
    Breast Cancer Res 12:R109. 2010
  10. pmc The androgen receptor CAG repeat polymorphism and modification of breast cancer risk in BRCA1 and BRCA2 mutation carriers
    Amanda B Spurdle
    Queensland Institute of Medical Research, Brisbane, Australia
    Breast Cancer Res 7:R176-83. 2005

Collaborators

Detail Information

Publications141 found, 100 shown here

  1. ncbi request reprint Detection of infectious organisms in archival prostate cancer tissues
    Melissa A Yow
    Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, VIC 3004, Australia
    BMC Cancer 14:579. 2014
    ..This study sought DNA evidence of candidate organisms in archival prostate cancer tissues with the aim of assessing if a subset of these cancers show any association with common genital infections...
  2. pmc The relationship between retinal vessel calibre and knee cartilage and BMLs
    Miranda L Davies-Tuck
    Department of Epidemiology and Preventive Medicine, Monash University, Central and Eastern Clinical School, Alfred Hospital, Melbourne, Vic, 3004, Australia
    BMC Musculoskelet Disord 13:255. 2012
    ....
  3. pmc Analysis of Xq27-28 linkage in the international consortium for prostate cancer genetics (ICPCG) families
    Joan E Bailey-Wilson
    Inherited Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Baltimore, MD 21224, USA
    BMC Med Genet 13:46. 2012
    ..Current evidence suggests that genetic linkage to prostate cancer has been found on several chromosomes including the X; however, identification of causative genes has been elusive...
  4. pmc The use of DNA from archival dried blood spots with the Infinium HumanMethylation450 array
    Jihoon E Joo
    Genetic Epidemiology Laboratory, Department of Pathology, The University of Melbourne, Victoria, 3010, Australia
    BMC Biotechnol 13:23. 2013
    ....
  5. pmc A longitudinal study of the association between dietary factors, serum lipids, and bone marrow lesions of the knee
    Dawn Dore
    Menzies Research Institute Tasmania, University of Tasmania, Private Bag 23, Hobart, Tasmania, 7000, Australia
    Arthritis Res Ther 14:R13. 2012
    ..Bone marrow lesions (BMLs) play an important role in knee osteoarthritis, but their etiology is not well understood. The aim of this longitudinal study was to describe the association between dietary factors, serum lipids, and BMLs...
  6. pmc Second to fourth digit ratio (2D:4D) and concentrations of circulating sex hormones in adulthood
    David C Muller
    Cancer Epidemiology Centre, The Cancer Council of Victoria, Melbourne, Australia
    Reprod Biol Endocrinol 9:57. 2011
    ..The objective of this study was to examine whether circulating concentrations of sex hormones and SHBG measured in adulthood was associated with 2D:4D...
  7. pmc Contribution of large genomic BRCA1 alterations to early-onset breast cancer selected for family history and tumour morphology: a report from The Breast Cancer Family Registry
    Letitia D Smith
    Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne, Melbourne, Victoria 3010, Australia
    Breast Cancer Res 13:R14. 2011
    ..We sought to test the value of selecting women for BRCA1 mutation testing on the basis of family history and/or breast tumour morphology criteria as well as the value of testing for large genomic alterations in BRCA1...
  8. pmc Assessing interactions between the associations of common genetic susceptibility variants, reproductive history and body mass index with breast cancer risk in the breast cancer association consortium: a combined case-control study
    Roger L Milne
    Genetic and Molecular Epidemiology Group, Human Cancer Genetics Programme, Spanish National Cancer Research Centre CNIO, Madrid, 28029, Spain
    Breast Cancer Res 12:R110. 2010
    ....
  9. pmc A PALB2 mutation associated with high risk of breast cancer
    Melissa C Southey
    Department of Pathology, The University of Melbourne, Victoria 3010, Australia
    Breast Cancer Res 12:R109. 2010
    ..Little is known about by how much or whether risk differs by mutation or family history, owing to the paucity of studies of cases unselected for family history...
  10. pmc The androgen receptor CAG repeat polymorphism and modification of breast cancer risk in BRCA1 and BRCA2 mutation carriers
    Amanda B Spurdle
    Queensland Institute of Medical Research, Brisbane, Australia
    Breast Cancer Res 7:R176-83. 2005
    ..Women with germline BRCA1 mutations who carry at least one AR allele with 28 or more repeats have been reported to have an earlier age at onset of breast cancer...
  11. pmc The AIB1 glutamine repeat polymorphism is not associated with risk of breast cancer before age 40 years in Australian women
    Karen G Montgomery
    Cancer Genetics Laboratory, Victorian Breast Cancer Research Consortium, Peter MacCallum Cancer Centre, St, Andrews Place, East Melbourne, Victoria, Australia
    Breast Cancer Res 7:R353-6. 2005
    ..It contains a glutamine repeat (CAG/CAA) polymorphism at its carboxyl-terminal region that may alter the transcriptional activation of the receptor and affect susceptibility to breast cancer through altered sensitivity to hormones...
  12. pmc CYP17 genetic polymorphism, breast cancer, and breast cancer risk factors: Australian Breast Cancer Family Study
    Jiun Horng Chang
    Centre for Genetic Epidemiology, The University of Melbourne, Victoria, Australia
    Breast Cancer Res 7:R513-21. 2005
    ..We attempted to replicate the findings of studies assessing such interactions with the -34T-->C polymorphism...
  13. pmc Meat consumption and risk of primary hip and knee joint replacement due to osteoarthritis: a prospective cohort study
    Yuanyuan Wang
    Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Alfred Hospital, Melbourne, VIC 3004, Australia
    BMC Musculoskelet Disord 12:17. 2011
    ..However, whether it affects the risk of knee and hip osteoarthritis is unknown. We performed a prospective cohort study to examine the relationship between meat consumption and risk of primary hip and knee replacement for osteoarthritis...
  14. pmc Validation of de-identified record linkage to ascertain hospital admissions in a cohort study
    Alison Beauchamp
    Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia
    BMC Med Res Methodol 11:42. 2011
    ..We sought to develop and validate a method for linking a cohort study to a state-wide hospital admissions dataset with limited availability of unique identifying variables...
  15. pmc The 4q27 locus and prostate cancer risk
    Elizabeth A Tindall
    Cancer Genetics Group, Children s Cancer Institute Australia for Medical Research, Sydney Children s Hospital, High St, Randwick, NSW, Australia
    BMC Cancer 10:69. 2010
    ..This region harbors two cytokine genes IL-2 and the recently described IL-21...
  16. pmc Relationship between body adiposity measures and risk of primary knee and hip replacement for osteoarthritis: a prospective cohort study
    Yuanyuan Wang
    Department of Epidemiology and Preventive Medicine, Monash University, Central and Eastern Clinical School, Alfred Hospital, Melbourne, VIC 3004, Australia
    Arthritis Res Ther 11:R31. 2009
    ..It is unknown whether the adipose mass and the distribution of adipose mass are associated with the risk of primary knee and hip replacement for osteoarthritis. The aim of the present investigation was to examine this in a cohort study...
  17. pmc Effect of antioxidants on knee cartilage and bone in healthy, middle-aged subjects: a cross-sectional study
    Yuanyuan Wang
    Department of Epidemiology and Preventive Medicine, Monash University, Central and Eastern Clinical School, Alfred Hospital, Melbourne, VIC 3004, Australia
    Arthritis Res Ther 9:R66. 2007
    ..While our findings need to be confirmed by longitudinal studies, they highlight the potential of the diet to modify the risk of osteoarthritis...
  18. pmc Dietary fatty acid intake affects the risk of developing bone marrow lesions in healthy middle-aged adults without clinical knee osteoarthritis: a prospective cohort study
    Yuanyuan Wang
    Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Alfred Hospital, Commercial Road, Melbourne, VIC 3004, Australia
    Arthritis Res Ther 11:R63. 2009
    ..The aim of this study was to examine the association between fatty acid consumption and the incidence of BMLs in healthy middle-aged adults without clinical knee OA...
  19. pmc Reduced rates of primary joint replacement for osteoarthritis in Italian and Greek migrants to Australia: the Melbourne Collaborative Cohort Study
    Yuanyuan Wang
    Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Alfred Hospital, Melbourne, VIC 3004, Australia
    Arthritis Res Ther 11:R86. 2009
    ..The aim of this study was to compare the rates of primary joint replacement for osteoarthritis for Italian and Greek migrants to Australia and Australian-born individuals...
  20. pmc Development of bone marrow lesions is associated with adverse effects on knee cartilage while resolution is associated with improvement--a potential target for prevention of knee osteoarthritis: a longitudinal study
    Miranda L Davies-Tuck
    Department of Epidemiology and Preventive Medicine, Monash University, Central and Eastern Clinical School, Alfred Hospital, Melbourne, VIC 3004, Australia
    Arthritis Res Ther 12:R10. 2010
    ..To examine the relationship between development or resolution of bone marrow lesions (BMLs) and knee cartilage properties in a 2 year prospective study of asymptomatic middle-aged adults...
  21. pmc Vastus medialis cross-sectional area is positively associated with patella cartilage and bone volumes in a pain-free community-based population
    Patricia A Berry
    Department of Epidemiology and Preventive Medicine, Monash University Central and Eastern Clinical School, Melbourne, Australia
    Arthritis Res Ther 10:R143. 2008
    ..The aim of this study was to examine potential determinants of vastus medialis and lateralis cross-sectional areas and the relationship between the cross-sectional area and patella cartilage and bone volumes...
  22. ncbi request reprint Cancer statistics: everything you wanted to know about the cancer registry data but were too afraid to ask
    Graham G Giles
    Victorian Cancer Registry, The Cancer Council Victoria, Melbourne, Victoria, Australia
    ANZ J Surg 74:931-4. 2004
    ..To promote the use of ANZ population cancer data, the following paper describes the principal statistics that are available and identifies common problems with their use...
  23. ncbi request reprint Body size and composition and risk of postmenopausal breast cancer
    Robert J Macinnis
    Cancer Epidemiology Centre, Cancer Control Research Institute, The Cancer Council Victoria, 1 Rathdowne Street, Carlton South, Victoria 3053, Australia
    Cancer Epidemiol Biomarkers Prev 13:2117-25. 2004
    ....
  24. ncbi request reprint Dietary carbohydrate, fibre, glycaemic index, glycaemic load and the risk of postmenopausal breast cancer
    Graham G Giles
    Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Australia
    Int J Cancer 118:1843-7. 2006
    ..43, 0.99), p = 0.005. Our data do not support a strong role for GI and GL in breast carcinogenesis but suggest that increased intake of fibre and carbohydrate may be associated with the diagnosis of cancers of more favourable prognosis...
  25. ncbi request reprint Sexual factors and prostate cancer
    G G Giles
    Cancer Epidemiology Centre, and Centre for Behavioural Research in Cancer, The Cancer Council Victoria, Melbourne, Australia
    BJU Int 92:211-6. 2003
    ..To assess whether prostate cancer might be related to hormone levels and, by inference, to differences in sexual activity...
  26. ncbi request reprint Early growth, adult body size and prostate cancer risk
    Graham G Giles
    Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia
    Int J Cancer 103:241-5. 2003
    ....
  27. ncbi request reprint Population-based estimate of the average age-specific cumulative risk of breast cancer for a defined set of protein-truncating mutations in BRCA1 and BRCA2. Australian Breast Cancer Family Study
    J L Hopper
    The University of Melbourne, Centre for Genetic Epidemiology, Carlton, Victoria, Australia
    Cancer Epidemiol Biomarkers Prev 8:741-7. 1999
    ..Breast cancer risk in BRCA1 or BRCA2 mutation carriers may be modified by other genetic or environmental factors. Genetic counselors may need to take into account the family history of the consultand...
  28. ncbi request reprint CFTR deltaF508 carrier status, risk of breast cancer before the age of 40 and histological grading in a population-based case-control study
    M C Southey
    Department of Pathology, Peter MacCallum Cancer Institute, Melbourne, Australia
    Int J Cancer 79:487-9. 1998
    ..A combination of our data with other large population-based samples of cases and controls is required to resolve this issue...
  29. ncbi request reprint Estrogen receptor polymorphism at codon 325 and risk of breast cancer in women before age forty
    M C Southey
    Department of Pathology and Research, Peter MacCallum Cancer Institute, Melbourne, Australia
    J Natl Cancer Inst 90:532-6. 1998
    ..28+/-0.05 versus 0.11+/-0.02; P<.001). To determine whether this polymorphism is a risk factor for early-onset breast cancer, we conducted a population-based, case-control-family study in Australia...
  30. pmc Prospective validation of the breast cancer risk prediction model BOADICEA and a batch-mode version BOADICEACentre
    R J MacInnis
    Cancer Epidemiology Centre, Cancer Council Victoria, Victoria, Melbourne, Australia
    Br J Cancer 109:1296-301. 2013
    ..It is uncertain whether BOADICEA performs adequately for populations outside the United Kingdom...
  31. pmc Second to fourth digit ratio (2D:4D), breast cancer risk factors, and breast cancer risk: a prospective cohort study
    D C Muller
    Cancer Epidemiology Centre, Cancer Council Victoria, 100 Drummond Street, Carlton South, Victoria 3053, Australia
    Br J Cancer 107:1631-6. 2012
    ..We aimed to assess whether 2D:4D measures are associated with breast cancer risk...
  32. ncbi request reprint Dietary intake of B vitamins and methionine and risk of lung cancer
    J K Bassett
    Cancer Epidemiology Centre, Cancer Council Victoria, Carlton South, Victoria, Australia
    Eur J Clin Nutr 66:182-7. 2012
    ..Disruption of one-carbon mechanism may affect cancer risk. We investigated prospectively the relationship between dietary intakes of methionine, B vitamins associated with one-carbon metabolism and risk of lung cancer...
  33. pmc Plasma concentration of Propionibacterium acnes antibodies and prostate cancer risk: results from an Australian population-based case-control study
    G Severi
    Cancer Epidemiology Centre, The Cancer Council of Victoria, Melbourne, Victoria 3053, Australia
    Br J Cancer 103:411-5. 2010
    ..The aim of our study was to test whether circulating levels of P. acnes antibodies are associated with prostate cancer risk and tumour characteristics using plasma samples from a population-based case-control study...
  34. doi request reprint Obesity and adiposity are associated with the rate of patella cartilage volume loss over 2 years in adults without knee osteoarthritis
    A J Teichtahl
    Department of Epidemiology and Preventive Medicine, Monash University, Central and Eastern Clinical School, Alfred Hospital, Melbourne, Australia
    Ann Rheum Dis 68:909-13. 2009
    ..The aim of this study was to determine whether measures of obesity and adiposity are associated with the rate of patella cartilage volume loss in healthy adults...
  35. ncbi request reprint Smoking and prostate cancer: findings from an Australian case-control study
    G G Giles
    Cancer Epidemiology Centre, Anti Cancer Council of Victoria, Melbourne, Australia
    Ann Oncol 12:761-5. 2001
    ..To examine the risk of smoking on histopathologically-confirmed moderate- and high-grade prostate cancer...
  36. ncbi request reprint Regressive logistic and proportional hazards disease models for within-family analyses of measured genotypes, with application to a CYP17 polymorphism and breast cancer
    Jisheng S Cui
    Centre for Genetic Epidemiology, The University of Melbourne, Melbourne, Victoria, Australia
    Genet Epidemiol 24:161-72. 2003
    ..This analytical approach is well-suited to the data that arise from population-based case-control-family studies, in which cases, controls and relatives are studied, and genotype is measured for some but not all subjects...
  37. pmc Morphological predictors of BRCA1 germline mutations in young women with breast cancer
    M C Southey
    Department of Pathology, Genetic Epidemiology Laboratory, Victoria, Carlton, Australia
    Br J Cancer 104:903-9. 2011
    ..We sought an optimal strategy for identifying carriers using family history, breast cancer morphology and hormone receptor status data...
  38. ncbi request reprint The relationship between the angle of the trochlear groove and patella cartilage and bone morphology--a cross-sectional study of healthy adults
    A J Teichtahl
    Department of Epidemiology and Preventive Medicine, Monash University, Central and Eastern Clinical School, Alfred Hospital, Melbourne, Victoria 3004, Australia
    Osteoarthritis Cartilage 15:1158-62. 2007
    ..This cross-sectional study investigated the relationship between the shape of the trochlear groove and patella cartilage and bone morphology in healthy adults...
  39. ncbi request reprint Body size and composition and prostate cancer risk
    Robert J Macinnis
    Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia
    Cancer Epidemiol Biomarkers Prev 12:1417-21. 2003
    ..2 (95% confidence interval, 1.2-4.1). For each 10-kg increase in fat mass, the risk ratio was 1.4 (95% confidence interval, 1.0-1.8). Energy imbalance may play a role in the development of aggressive prostate cancer...
  40. ncbi request reprint Adult serum cytokine concentrations and the persistence of asthma
    R K Kandane-Rathnayake
    Centre for MEGA Epidemiology, Melbourne School of Population Health, The University of Melbourne, Melbourne, Vic, Australia
    Int Arch Allergy Immunol 161:342-50. 2013
    ..Cytokines play a pivotal role in regulating the development and persistence of the inflammatory process in asthma. Our aim was to investigate whether asthma persistence or remission is associated with a specific cytokine profile...
  41. doi request reprint Consumption of animal products, their nutrient components and postmenopausal circulating steroid hormone concentrations
    M T Brinkman
    Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Australia
    Eur J Clin Nutr 64:176-83. 2010
    ..We aimed to investigate the association between consumption of animal products and the plasma concentrations of steroid hormones and sex hormone-binding globulin (SHBG)...
  42. doi request reprint The natural history of bone marrow lesions in community-based adults with no clinical knee osteoarthritis
    M L Davies-Tuck
    Department of Epidemiology and Preventive Medicine, Monash University, Central and Eastern Clinical School, Alfred Hospital, Melbourne, Australia
    Ann Rheum Dis 68:904-8. 2009
    ..This study in a healthy, pain-free population aimed to examine the natural history of BML; factors associated with incidence and progression of BML over 2 years and whether incident BML are associated with the development of pain...
  43. ncbi request reprint Bone marrow lesions predict progression of cartilage defects and loss of cartilage volume in healthy middle-aged adults without knee pain over 2 yrs
    A E Wluka
    Department of Epidemiology and Preventive Medicine, Monash University Medical School, Alfred Hospital, Prahran, Melbourne, Victoria 3004, Australia
    Rheumatology (Oxford) 47:1392-6. 2008
    ..In knee OA, the presence of bone marrow lesions (BMLs) predicts pain and progression of disease. Their occurrence has been described in healthy, pain-free subjects, but whether their presence affects change in cartilage is unknown...
  44. pmc Increased cancer risks for relatives of very early-onset breast cancer cases with and without BRCA1 and BRCA2 mutations
    G S Dite
    Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Level 1, 723 Swanston Street, Melbourne, Carlton VIC 3053, Australia
    Br J Cancer 103:1103-8. 2010
    ..Little is known regarding cancer risks for relatives of women with very early-onset breast cancer...
  45. pmc Risks of Lynch syndrome cancers for MSH6 mutation carriers
    Laura Baglietto
    Cancer Epidemiology Centre, Victorian Cancer Registry, Carlton, Victoria, Australia
    J Natl Cancer Inst 102:193-201. 2010
    ..Germline mutations in MSH6 account for 10%-20% of Lynch syndrome colorectal cancers caused by hereditary DNA mismatch repair gene mutations. Because there have been only a few studies of mutation carriers, their cancer risks are uncertain...
  46. pmc Segregation analyses of 1,476 population-based Australian families affected by prostate cancer
    J Cui
    Centre for Genetic Epidemiology, The University of Melbourne, Carlton, Victoria 3053, Australia
    Am J Hum Genet 68:1207-18. 2001
    ..Within discussed limitations, these analyses confirm the genetic heterogeneity, of prostate cancer susceptibility, that is becoming evident from linkage analyses, and they may aid future efforts in gene discovery...
  47. pmc Dietary patterns and risk of breast cancer
    L Baglietto
    Cancer Epidemiology Centre, The Cancer Council Victoria, 100 Drummond Street, Carlton, Melbourne, Victoria 3053, Australia
    Br J Cancer 104:524-31. 2011
    ..Evidence is emerging that prudent/healthy dietary patterns might be associated with a reduced risk of breast cancer...
  48. ncbi request reprint Hormone replacement therapy and accuracy of mammographic screening
    A M Kavanagh
    Cancer Epidemiology Centre, Anti Cancer Council of Victoria, Australia
    Lancet 355:270-4. 2000
    ..Hormone replacement therapy (HRT) is commonly used and may affect the accuracy of mammographic screening...
  49. ncbi request reprint Body size and composition and risk of rectal cancer (Australia)
    Robert J Macinnis
    Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Carlton South, Vic, Australia
    Cancer Causes Control 17:1291-7. 2006
    ..The relationship between rectal cancer risk and central adiposity, overall fat mass, and fat-free mass is unknown...
  50. ncbi request reprint Body size and composition and colon cancer risk in women
    Robert J Macinnis
    Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia
    Int J Cancer 118:1496-500. 2006
    ..Central adiposity appears to be associated with colon cancer risk in women...
  51. ncbi request reprint Men with colorectal cancer are predisposed to prostate cancer
    Andrew R Moot
    Cabrini Monash University Academic Surgical Unit, Cancer Epidemiology Centre and Victorian Cancer Registry, Anti Cancer Council of Victoria, and Cabrini Hospital, Victoria, Australia
    ANZ J Surg 73:289-93. 2003
    ..The objective of the present study was to investigate the relationship between colorectal and prostate cancer...
  52. doi request reprint Evaluation of an FFQ for assessment of antioxidant intake using plasma biomarkers in an ethnically diverse population
    Allison M Hodge
    Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Australia
    Public Health Nutr 12:2438-47. 2009
    ....
  53. ncbi request reprint A comparison of adiposity measures as predictors of all-cause mortality: the Melbourne Collaborative Cohort Study
    Julie A Simpson
    Cancer Epidemiology Centre, Council Council Victoria, and Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, University of Melbourne, Level 2 723 Swanston St, Carlton, Victoria 3053, Australia
    Obesity (Silver Spring) 15:994-1003. 2007
    ..Our goal was to examine five different measures of adiposity as predictors of all-cause mortality...
  54. ncbi request reprint Variants in the prostate-specific antigen (PSA) gene and prostate cancer risk, survival, and circulating PSA
    Gianluca Severi
    Cancer Epidemiology Center, The Cancer Council Victoria, Melbourne, Victoria, Australia
    Cancer Epidemiol Biomarkers Prev 15:1142-7. 2006
    ..The genotypes and haplotypes studied might be associated with the PSA gene function or be in linkage disequilibrium with other unmeasured and functional variants in the PSA or other genes...
  55. ncbi request reprint Average volume of alcohol consumed, type of beverage, drinking pattern and the risk of death from all causes
    Laura Baglietto
    Cancer Epidemiology Centre, The Cancer Council of Victoria, Carlton VIC 3053, Melbourne, Australia
    Alcohol Alcohol 41:664-71. 2006
    ..The objective was to investigate associations between average volume of alcohol consumption, type of beverage and drinking pattern and all-cause mortality in the Melbourne Collaborative Cohort Study...
  56. ncbi request reprint Familial risks, early-onset breast cancer, and BRCA1 and BRCA2 germline mutations
    Gillian S Dite
    Centre for Genetic Epidemiology, The University of Melbourne, Melbourne, Australia
    J Natl Cancer Inst 95:448-57. 2003
    ....
  57. pmc Tumour morphology predicts PALB2 germline mutation status
    Z L Teo
    Genetic Epidemiology Laboratory, The University of Melbourne, Melbourne, Victoria 3010, Australia
    Br J Cancer 109:154-63. 2013
    ..We sought to determine whether morphological features of breast tumours can predict PALB2 germline mutation status...
  58. pmc Rare mutations in XRCC2 increase the risk of breast cancer
    D J Park
    Genetic Epidemiology Laboratory, The University of Melbourne, Victoria, Australia
    Am J Hum Genet 90:734-9. 2012
    ..This study demonstrates the power of massively parallel sequencing for discovering susceptibility genes for common, complex diseases...
  59. ncbi request reprint Familial patterns of covariation for cardiovascular risk factors in adults: The Victorian Family Heart Study
    S B Harrap
    Department of Physiology, University of Melbourne, Parkville, Victoria, Australia
    Am J Epidemiol 152:704-15. 2000
    ..On a background of genetic influences, there are periods in early life during which the family environment cements long-term correlations between adult relatives in cardiovascular risk factors...
  60. ncbi request reprint The sensitivity, specificity, and positive predictive value of screening mammography and symptomatic status
    A M Kavanagh
    Australian Research Centre in Sex, Health and Society, La Trobe University, Melbourne, Victoria, Australia
    J Med Screen 7:105-10. 2000
    ..To examine whether the accuracy of screening mammography varies according to symptomatic status reported at the time of screening...
  61. pmc The role of SMAD4 in early-onset colorectal cancer
    S G Royce
    Department of Pathology, University of Melbourne, Victoria, Australia
    Colorectal Dis 12:213-9. 2010
    ..Chromosomal loss within the region of 18q and loss of SMAD4 expression have been reported to be frequent somatic events during colorectal cancer tumour progression; however, their associations with age at onset have not been widely studied...
  62. pmc Second to fourth digit ratio (2D:4D) and prostate cancer risk in the Melbourne Collaborative Cohort Study
    D C Muller
    Cancer Epidemiology Centre, Cancer Council of Victoria, Melbourne, Victoria, Australia
    Br J Cancer 105:438-40. 2011
    ..Recent studies have reported a strong association between 2D:4D and risk of prostate cancer...
  63. ncbi request reprint Circulating insulin-like growth factor-I and binding protein-3 and the risk of breast cancer
    Laura Baglietto
    Cancer Epidemiology Centre, The Cancer Council Victoria, 1 Rathdowne Street, Carlton, Melbourne, Victoria 3053, Australia
    Cancer Epidemiol Biomarkers Prev 16:763-8. 2007
    ..More prospective studies are needed to clarify the age dependence of the association between IGF-I and IGFBP-3 and breast cancer...
  64. ncbi request reprint Uptake of offer to receive genetic information about BRCA1 and BRCA2 mutations in an Australian population-based study
    Louise A Keogh
    Centre for Genetic Epidemiology, University of Melbourne, 723 Swanston Street, Carlton, Victoria 3053, Australia
    Cancer Epidemiol Biomarkers Prev 13:2258-63. 2004
    ....
  65. ncbi request reprint Dietary patterns and cardiovascular mortality in the Melbourne Collaborative Cohort Study
    Linton R Harriss
    Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia
    Am J Clin Nutr 86:221-9. 2007
    ..Despite increased cardiovascular disease risk factors, migrants to Australia from Mediterranean countries have lower mortality than do native-born Australians. Dietary patterns may contribute to this...
  66. ncbi request reprint Obesity and outcomes in premenopausal and postmenopausal breast cancer
    Sherene Loi
    Peter MacCallum Cancer Centre, 723 Swanston Street, Carlton, Victoria 3053, Australia
    Cancer Epidemiol Biomarkers Prev 14:1686-91. 2005
    ..Obesity is associated with adverse outcomes in postmenopausal women with breast cancer. In premenopausal women, the association is less clear...
  67. ncbi request reprint Foods, nutrients and prostate cancer
    Allison M Hodge
    Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Australia
    Cancer Causes Control 15:11-20. 2004
    ..To examine the risk of prostate cancer associated with foods and nutrients, including individual fatty acids and carotenoids...
  68. ncbi request reprint Body size and composition and the risk of lymphohematopoietic malignancies
    Robert J Macinnis
    Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia
    J Natl Cancer Inst 97:1154-7. 2005
    ..83, 95% CI = 1.15 to 2.90; P = .01), and waist circumference (per 10-cm increase HR = 1.35, 95% CI = 1.06 to 1.72; P = .02). Lymphoproliferative malignancies and subgroups showed little relationship with body size...
  69. ncbi request reprint Androgenetic alopecia and prostate cancer: findings from an Australian case-control study
    Graham G Giles
    Cancer Epidemiology Centre, Anti Cancer Council of Victoria, Melbourne, VIC 3053 Australia
    Cancer Epidemiol Biomarkers Prev 11:549-53. 2002
    ..91 (1.59-5.32) for vertex baldness; and 1.95 (1.10-3.45) for frontal and vertex baldness. This association between the pattern of AA and prostate cancer points to shared androgen pathways that are worthy of additional investigation...
  70. pmc Associations between congenital malformations and childhood cancer. A register-based case-control study
    A E Altmann
    Consultative Council on Obstetric and Paediatric Mortality and Morbidity, Perinatal Data Collection Unit, Department of Human Services, Victoria, Australia
    Br J Cancer 78:1244-9. 1998
    ..The usefulness of record linkage between accurate population-based registers in the epidemiological study of disease has also been reinforced...
  71. pmc BRCA1 mutations and other sequence variants in a population-based sample of Australian women with breast cancer
    M C Southey
    Department of Pathology and Research, Peter MacCallum Cancer Institute, Melbourne, Victoria, Australia
    Br J Cancer 79:34-9. 1999
    ..6%). Seven rare variants were also detected, but for none was there evidence of a strong effect on breast cancer susceptibility. Therefore, on a population basis, rare variants are likely to contribute little to breast cancer incidence...
  72. ncbi request reprint A positive association of smoking and articular knee joint cartilage in healthy people
    T L Racunica
    Department of Epidemiology and Preventive Medicine, Monash University, Central and Eastern Clinical School, Alfred Hospital, Melbourne, Victoria 3004, Australia
    Osteoarthritis Cartilage 15:587-90. 2007
    ..To determine whether smoking affects knee cartilage in healthy adults by examining the association of tobacco use with tibial cartilage volume and tibiofemoral cartilage defects...
  73. ncbi request reprint A protein-truncating mutation in CYP17A1 in three sisters with early-onset breast cancer
    John L Hopper
    Centre for Genetic Epidemiology, The University of Melbourne, Carlton, Victoria, Australia
    Hum Mutat 26:298-302. 2005
    ....
  74. doi request reprint Dietary patterns and prostate cancer risk
    David C Muller
    Cancer Epidemiology Centre, The Cancer Council of Victoria and Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Melbourne, Australia
    Cancer Epidemiol Biomarkers Prev 18:3126-9. 2009
    ..87 to 1.14 and all 95% confidence intervals included 1. The analyses by aggressiveness, Gleason score groups, and age at diagnosis did not show any association (all P(trend) > 0.07)...
  75. ncbi request reprint Body size, weight change, and risk of colon cancer
    Julie K Bassett
    Cancer Epidemiology Centre, Cancer Council Victoria, Carlton, Victoria, Australia
    Cancer Epidemiol Biomarkers Prev 19:2978-86. 2010
    ..Few studies have investigated effects of weight change on colon cancer risk...
  76. ncbi request reprint The beliefs, and reported and intended behaviors of unaffected men in response to their family history of prostate cancer
    Ruth Cowan
    Department of Paediatrics, The University of Melbourne, Parkville, Victoria, Australia
    Genet Med 10:430-8. 2008
    ....
  77. doi request reprint Circulating steroid hormone concentrations in postmenopausal women in relation to body size and composition
    Laura Baglietto
    Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Vic, Australia
    Breast Cancer Res Treat 115:171-9. 2009
    ..This effect requires around 6 years to be detectable by way of circulating steroid hormone levels...
  78. ncbi request reprint Asthma, asthma medications, and prostate cancer risk
    Gianluca Severi
    Cancer Epidemiology Centre, The Cancer Council of Victoria, Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Carlton, VIC 3053, Australia
    Cancer Epidemiol Biomarkers Prev 19:2318-24. 2010
    ..The aim of this study was to assess whether a history of asthma or the use of asthma medications is associated with prostate cancer risk...
  79. pmc HFE Cys282Tyr homozygotes with serum ferritin concentrations below 1000 microg/L are at low risk of hemochromatosis
    Katrina J Allen
    Murdoch Childrens Research Institute, Melbourne, Australia
    Hepatology 52:925-33. 2010
    ..22) and for normal SF was 6% (arthritis medicine use, 95% confidence interval = -3%, 16%; P = 0.11)...
  80. pmc Does dietary folate intake modify effect of alcohol consumption on breast cancer risk? Prospective cohort study
    Laura Baglietto
    Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, 100 Drummond Street, Carlton, Victoria 3053, Australia
    BMJ 331:807. 2005
    ..To evaluate the effect of dietary folate intake on the relation between alcohol consumption and breast cancer risk...
  81. ncbi request reprint Cancer risks for mismatch repair gene mutation carriers: a population-based early onset case-family study
    Mark A Jenkins
    Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Victoria, Australia
    Clin Gastroenterol Hepatol 4:489-98. 2006
    ..These may be overestimates, due to analytic problems, and not generalizable. We estimated average cancer risks for mutations identified in population-based early onset colorectal cancer cases (probands) unselected for family history...
  82. doi request reprint Fat consumption and its association with age-related macular degeneration
    Elaine W T Chong
    Centre for Eye Research Australia, University of Melbourne, East Melbourne, Victoria, Australia
    Arch Ophthalmol 127:674-80. 2009
    ..To evaluate associations between past dietary fat intake and the prevalence of age-related macular degeneration (AMD)...
  83. pmc Population-based, case-control-family design to investigate genetic and environmental influences on melanoma risk: Australian Melanoma Family Study
    Anne E Cust
    Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, School of Population Health, The University of Melbourne, Level 1, Melbourne, Victoria, Australia
    Am J Epidemiol 170:1541-54. 2009
    ..The authors discuss methodological and analytical issues related to the study design and conduct, as well as the potentially novel insights the study can deliver...
  84. doi request reprint The effect of socioeconomic status on survival from colorectal cancer in the Melbourne Collaborative Cohort Study
    Helen L Kelsall
    The Cancer Council Victoria, Carlton, Victoria 3053, Australia
    Soc Sci Med 68:290-7. 2009
    ....
  85. ncbi request reprint Alcohol consumption and prostate cancer risk: results from the Melbourne collaborative cohort study
    Laura Baglietto
    Cancer Epidemiology Centre, Cancer Council of Victoria, Melbourne, Vic, Australia
    Int J Cancer 119:1501-4. 2006
    ..Our results show that alcohol consumption does not influence overall prostate cancer incidence but we found suggestive evidence that alcohol consumption might decrease the incidence of aggressive prostate cancer and mortality...
  86. pmc HFE C282Y homozygotes are at increased risk of breast and colorectal cancer
    Nicholas J Osborne
    Gut and Liver, Murdoch Childrens Research Institute, Melbourne, Vic, Australia
    Hepatology 51:1311-8. 2010
    ..43, 2.15; P = 0.92). C282Y/H63D compound heterozygotes were not at increased risk for colorectal cancer (HR = 1.27; 95% CI = 0.80, 2.01), breast cancer (HR = 1.16; 95% CI = 0.74, 1.84), or prostate cancer (HR = 1.08; 95% CI = 0.68, 1.70)...
  87. doi request reprint Circulating steroid hormone levels and risk of breast cancer for postmenopausal women
    Laura Baglietto
    Cancer Epidemiology Centre, The Cancer Council Victoria, Victoria, Melbourne, Australia
    Cancer Epidemiol Biomarkers Prev 19:492-502. 2010
    ....
  88. ncbi request reprint Circulating steroid hormones and the risk of prostate cancer
    Gianluca Severi
    Cancer Epidemiology Centre, The Cancer Council Victoria, University of Melbourne, Melbourne, Australia
    Cancer Epidemiol Biomarkers Prev 15:86-91. 2006
    ..06, 0.2, and 0.1, respectively). High levels of testosterone and adrenal androgens are thus associated with reduced risk of aggressive prostate cancer but not with nonaggressive disease...
  89. doi request reprint Using mammographic density to improve breast cancer screening outcomes
    Anne M Kavanagh
    Key Centre for Women s Health in Society, School of Population Health, University of Melbourne, Melbourne, Australia
    Cancer Epidemiol Biomarkers Prev 17:2818-24. 2008
    ..There would be little additional benefit in targeting screening based on age and hormone therapy use...
  90. ncbi request reprint The common variant rs1447295 on chromosome 8q24 and prostate cancer risk: results from an Australian population-based case-control study
    Gianluca Severi
    Cancer Epidemiology Centre, The Cancer Council Victoria, 1 Rathdowne Street, Carlton, Victoria 3053, Australia
    Cancer Epidemiol Biomarkers Prev 16:610-2. 2007
    ....
  91. ncbi request reprint Dietary patterns and diabetes incidence in the Melbourne Collaborative Cohort Study
    Allison M Hodge
    Cancer Epidemiology Centre, The Cancer Council Victoria, 1 Rathdowne Street, Carlton, Victoria 3053, Australia
    Am J Epidemiol 165:603-10. 2007
    ..Avoidance of a dietary pattern including meats and fatty foods, as well as adherence to a pattern including salad and cooked vegetables, is recommended...
  92. ncbi request reprint Rectal cancer in Victoria in 1994: patterns of reported management
    K Chip Farmer
    Victorian Cancer Registry, Anti Cancer Council of Victoria, Carlton, Australia
    ANZ J Surg 72:265-70. 2002
    ..A retrospective survey of medical practitioners was conducted to describe the management of patients newly diagnosed with rectal cancer in 1994, prior to the publication of best practice guidelines...
  93. ncbi request reprint Plasma phospholipid fatty acid composition as a biomarker of habitual dietary fat intake in an ethnically diverse cohort
    Allison M Hodge
    Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Australia
    Nutr Metab Cardiovasc Dis 17:415-26. 2007
    ....
  94. ncbi request reprint A comparison of different methods for including 'age at menopause' in analyses of the association between hormone replacement therapy use and breast cancer
    Julie A Simpson
    Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne and the Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, University of Melbourne, Melbourne, Australia
    J Fam Plann Reprod Health Care 33:11-6. 2007
    ....
  95. ncbi request reprint Epidemiological investigation of prostate cancer
    Graham G Giles
    Cancer Epidemiology Centre, Cancer Control Research Institute, Carlton South, Australia
    Methods Mol Med 81:1-19. 2003
  96. ncbi request reprint Measures of familial aggregation depend on definition of family history: meta-analysis for colorectal cancer
    Laura Baglietto
    Cancer Epidemiology Centre, The Cancer Council of Victoria, 100 Rathdowne Street, Carlton, Melbourne, Victoria 3053, Australia
    J Clin Epidemiol 59:114-24. 2006
    ....
  97. ncbi request reprint Circulating insulin-like growth factor-I and binding protein-3 and risk of prostate cancer
    Gianluca Severi
    Cancer Epidemiology Centre, Cancer Council Victoria, 1 Rathdowne Street, Carlton, Victoria 3053, Australia
    Cancer Epidemiol Biomarkers Prev 15:1137-41. 2006
    ..49 (95% confidence interval, 1.11-2.00). The HRs did not differ by tumor aggressiveness or age at onset (all Ps > or = 0.4). In our study, high levels of IGFBP-3 but not IGF-I were associated with an increased risk of prostate cancer...
  98. ncbi request reprint Prognosis of premenopausal breast cancer and childbirth prior to diagnosis
    Kelly Anne Phillips
    Peter MacCallum Cancer Centre, University of Melbourne, Carlton, Victoria 3053, Australia
    J Clin Oncol 22:699-705. 2004
    ..The time interval between last childbirth and subsequent breast cancer diagnosis is emerging as an important prognostic factor for premenopausal women...
  99. ncbi request reprint Plasma phospholipid and dietary fatty acids as predictors of type 2 diabetes: interpreting the role of linoleic acid
    Allison M Hodge
    Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Australia
    Am J Clin Nutr 86:189-97. 2007
    ..Dietary fatty acids may be associated with diabetes but are difficult to measure accurately...
  100. ncbi request reprint Body size and composition and colon cancer risk in men
    Robert J Macinnis
    Cancer Epidemiology Centre, The Cancer Council Victoria, 1 Rathdowne Street, Carlton South, Melbourne, Victoria 3053, Australia
    Cancer Epidemiol Biomarkers Prev 13:553-9. 2004
    ..It is uncertain whether this relationship is due to non-adipose mass, adipose mass, distribution of adipose mass such as central adiposity, or all three...
  101. ncbi request reprint Is cancer risk associated with anger control and negative affect? Findings from a prospective cohort study
    Victoria M White
    Centre for Behavioural Research in Cancer, The Cancer Council Victoria, 1 Rathdowne Street, Carlton VIC 3053, Australia
    Psychosom Med 69:667-74. 2007
    ..To examine the associations between anger control and negative affect and the risk of five common cancers and total cancers. Possible associations between emotional states and the risk of cancer have long been postulated...