Research Topics
| Shivakumar ChitturiSummaryAffiliation: The Canberra Hospital Country: Australia Publications
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Detail Information
Publications
Nonalcoholic fatty liver in Asia: Firmly entrenched and rapidly gaining groundShivakumar Chitturi
The Canberra Hospital, Australian Capital Territory, Australia
J Gastroenterol Hepatol 26:163-72. 2011..Attention should be paid to prevention through public education of campaigns addressing the increase in both adult and childhood obesity...
Treatment options for nonalcoholic Fatty liver diseaseShivakumar Chitturi
Australian National University Medical School, Gastroenterology and Hepatology Unit, Canberra Hospital, Australian Capital Territory, Australia
Therap Adv Gastroenterol 1:173-89. 2008..Moreover, issues related to weight gain, cardiovascular risk need to be addressed. The use of endocannabinoid antagonists and insulin secretagogues are novel strategies to combat this disorder...
Hepatotoxic slimming aids and other herbal hepatotoxinsShivakumar Chitturi
Gastroenterology and Hepatology Unit, The Canberra Hospital, Canberra, Australian Capital Territory, Australia
J Gastroenterol Hepatol 23:366-73. 2008....
Non-alcoholic fatty liver disease in the Asia-Pacific region: definitions and overview of proposed guidelinesShivakumar Chitturi
Gastroenterology and Hepatology Unit, The Canberra Hospital, Canberra, Australian Capital Territory, Garran, Australia
J Gastroenterol Hepatol 22:778-87. 2007..The present document reviews the reasoning and evidence behind the APWP-NAFLD proposals for definition, assessment, and management of NAFLD in the Asia-Pacific region...
Postprandial hyperinsulinemia is universal in non-diabetic patients with nonalcoholic fatty liver diseaseJayani Manchanayake
Gastroenterology and Hepatology Unit, The Australian National University Medical School, Canberra, Australian Capital Territory, Australia
J Gastroenterol Hepatol 26:510-6. 2011..Relationships between hyperglycemia, postprandial hyperinsulinemia and NAFLD severity also need clarification...
Guidelines for the assessment and management of non-alcoholic fatty liver disease in the Asia-Pacific region: executive summaryGeoffrey C Farrell
Gastroenterology and Hepatology Unit, The Canberra Hospital, Canberra, Australian Capital Territory, Garran, Australia
J Gastroenterol Hepatol 22:775-7. 2007
Mechanisms and implications of age-related changes in the liver: nonalcoholic Fatty liver disease in the elderlyLay Gan
Liver Research Group, Gastroenterology and Hepatology Unit, The Canberra Hospital, Australian National University Medical School, Yamba Drive, Garran, ACT 2605, Australia
Curr Gerontol Geriatr Res 2011:831536. 2011..An approach to the management of NASH and its complications in the elderly, will also be presented here...
What are the risk factors and settings for non-alcoholic fatty liver disease in Asia-Pacific?Jian Gao Fan
Center for Fatty Liver Disease, Shanghai First People s Hospital, Jiaotong University, Shanghai, China
J Gastroenterol Hepatol 22:794-800. 2007..In addition, a perspective of NAFLD beyond its hepatic consequences is now warranted; this needs to be considered in relation to management guidelines for affected individuals...
Non-alcoholic steatohepatitis in the Asia-Pacific region: future shock?Shivakumar Chitturi
Storr Liver Unit, Westmead Millennium Institute, University of Sydney, Westmead Hospital, Westmead, New South Wales, Australia
J Gastroenterol Hepatol 19:368-74. 2004..Pharmacotherapy may play a role in selected individuals. A regional agenda for case definition, future study and public health initiatives is urgently required...
TNF-alpha as therapeutic target in NASH: tried, but not yet provenShivakumar Chitturi
J Gastroenterol Hepatol 22:613-4. 2007
HFE mutations, hepatic iron, and fibrosis: ethnic-specific association of NASH with C282Y but not with fibrotic severityShivakumar Chitturi
Storr Liver Unit, Westmead Millennium Institute, University of Sydney at Westmead Hospital, Westmead, New South Wales 2145, Australia
Hepatology 36:142-9. 2002..In conclusion, hepatic iron is not a factor linked to hepatic fibrogenesis in patients with NASH. HFE mutations do not confer an additional risk of hepatic fibrosis in this disorder...
Serum leptin in NASH correlates with hepatic steatosis but not fibrosis: a manifestation of lipotoxicity?Shivakumar Chitturi
Storr Liver Unit, Westmead Millennium Institute, University of Sydney, Westmead Hospital, New South Wales, Australia
Hepatology 36:403-9. 2002..We propose that the relationship between leptin and steatosis reflects a pathogenic role of leptin in hepatic insulin resistance and/or a failure of the antisteatotic actions of leptin ("peripheral leptin resistance")...
Interaction of iron, insulin resistance, and nonalcoholic steatohepatitisShivakumar Chitturi
Storr Liver Unit, Westmead Millennium Institute, University of Sydney, Westmead, New South Wales 2145, Australia
Curr Gastroenterol Rep 5:18-25. 2003..A recent study showed improvement in insulin sensitivity with the use of venesection in patients with NAFLD, but this approach cannot be implemented without extensive review...
Hepatitis B and fatty liver: causal or coincidental?Jian Gao Fan
J Gastroenterol Hepatol 23:679-81. 2008
Transjugular liver biopsy effecting changes in clinical managementDavid Lee
Department of Radiology, Westmead Hospital and Westmead Millennium Institute, University of Sydney, Sydney, Australia
Australas Radiol 47:117-20. 2003..Transjugular liver biopsies can be effectively and safely performed in high-risk patients with impaired coagulation. They aid accurate histological appraisal of liver dysfunction in these patients and influence clinical decision-making...
Fatty liver now, diabetes and heart attack later? The liver as a barometer of metabolic healthShivakumar Chitturi
J Gastroenterol Hepatol 22:967-9. 2007
Long-term outcomes of cirrhosis in nonalcoholic steatohepatitis compared with hepatitis CJason M Hui
Storr Liver Unit, Westmead Millennium Institute, and Department of Gastroenterology and Hepatology, Westmead Hospital, University of Sydney, NSW, Australia
Hepatology 38:420-7. 2003..In conclusion, liver failure is the main cause of morbidity and mortality in NASH-associated cirrhosis. The prognosis is either similar or less severe than HCV-cirrhosis, except that HCC appears less common...
NASH and insulin resistance: Insulin hypersecretion and specific association with the insulin resistance syndromeShivakumar Chitturi
Storr Liver Unit, Westmead Millennium Institute, University of Sydney, New South Wales, Australia
Hepatology 35:373-9. 2002..IR is present in mild as well as advanced cases of NASH but is unusual in chronic HCV of similar fibrotic severity...
