Research Topics
| Alan CassSummaryAffiliation: The George Institute for International Health Country: Australia Publications
| Collaborators
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Detail Information
Publications
Study Protocol--accurate assessment of kidney function in Indigenous Australians: aims and methods of the eGFR studyLouise J Maple-Brown
Menzies School of Health Research, Institute of Advanced Studies, Charles Darwin University, Darwin, Australia
BMC Public Health 10:80. 2010....- Oxpentifylline versus placebo in the treatment of erythropoietin-resistant anaemia: a randomized controlled trialDavid Wayne Johnson
Australian Kidney Trials Network, School of Population Health, University of Queensland, Brisbane, Australia
BMC Nephrol 9:8. 2008..The main hypothesis of this study is that Oxpentifylline administration will effectively treat erythropoietin- or darbepoietin-resistant anaemia in chronic kidney disease patients... - Preventing AVF thrombosis: the rationale and design of the Omega-3 fatty acids (Fish Oils) and Aspirin in Vascular access OUtcomes in REnal Disease (FAVOURED) studyAshley Irish
Renal Unit, Royal Perth Hospital, Perth, WA, Australia
BMC Nephrol 10:1. 2009.... 
Decision-making about suitability for kidney transplantation: Results of a national survey of Australian nephrologistsAlan Cass
The George Institute for International Health, Central Clinical School, University of Sydney, and Statewide Renal Services, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia
Nephrology (Carlton) 12:299-304. 2007..Given the reduced access to transplantation for Indigenous Australians, the role of patient's ethnicity was of particular interest...- Lowering blood pressure reduces renal events in type 2 diabetesBastiaan E De Galan
George Institute for International Health, University of Sydney, Sydney, NSW, Australia
J Am Soc Nephrol 20:883-92. 2009..We could not identify a BP threshold below which renal benefit is lost... - Efficacy and safety of routine blood pressure lowering in older patients with diabetes: results from the ADVANCE trialToshiharu Ninomiya
The George Institute for International Health, University of Sydney, New South Wales, Australia
J Hypertens 28:1141-9. 2010.... 
Aspirin is beneficial in hypertensive patients with chronic kidney disease: a post-hoc subgroup analysis of a randomized controlled trialMeg J Jardine
The George Institute for Global Health, Sydney, Australia Concord Repatriation General Hospital, Sydney, Australia
J Am Coll Cardiol 56:956-65. 2010..The purpose of this study was to determine the benefit and risk associated with antiplatelet therapy in the chronic kidney disease (CKD) population...- Cardiovascular risk management in chronic kidney disease in general practice (the AusHEART study)Mona Razavian
The George Institute for Global Health, Sydney, Australia
Nephrol Dial Transplant 27:1396-402. 2012..The objectives of this study were to assess the prevalence, general practitioner (GP) awareness and extent of current evidence-practice gaps in the management of CKD in Australian primary care... - Combined effects of routine blood pressure lowering and intensive glucose control on macrovascular and microvascular outcomes in patients with type 2 diabetes: New results from the ADVANCE trialSophia Zoungas
The George Institute for International Health, University of Sydney, Sydney, New South Wales, Australia
Diabetes Care 32:2068-74. 2009..To assess the magnitude and independence of the effects of routine blood pressure lowering and intensive glucose control on clinical outcomes in patients with long-standing type 2 diabetes... - Factors that influence the decision to be an organ donor: a systematic review of the qualitative literatureMichelle J Irving
School of Public Health, The University of Sydney, Sydney, Australia
Nephrol Dial Transplant 27:2526-33. 2012..We conducted a systematic review of qualitative studies that explored community attitudes towards living and deceased solid organ donation to inform strategies to improve organ donation rates... - Prediction of kidney-related outcomes in patients with type 2 diabetesMeg J Jardine
George Institute For Global Health, Sydney, Australia
Am J Kidney Dis 60:770-8. 2012..Tools are needed to predict which individuals with diabetes will develop kidney disease and its complications... - Cost-effectiveness of screening and optimal management for diabetes, hypertension, and chronic kidney disease: a modeled analysisKirsten Howard
School of Public Health, University of Sydney, and The Royal Prince Alfred Hospital, Sydney, NSW, Australia
Value Health 13:196-208. 2010..We therefore sought to estimate the costs and health outcomes of alternative strategies to prevent end-stage kidney disease, compared with usual care... - Nephrologists' perspectives on waitlisting and allocation of deceased donor kidneys for transplantAllison Tong
Centre for Kidney Research, The Children s Hospital at Westmead, Sydney, NSW, Australia
Am J Kidney Dis 58:704-16. 2011..This study aims to elicit nephrologists' perspectives on waitlisting patients for kidney transplant and the allocation of deceased kidneys... - If you can't comply with dialysis, how do you expect me to trust you with transplantation? Australian nephrologists' views on indigenous Australians' 'non-compliance' and their suitability for kidney transplantationKate Anderson
The George Institute for Global Health, Sydney, Australia
Int J Equity Health 11:21. 2012.... - Patient preferences for the allocation of deceased donor kidneys for transplantation: a mixed methods studyAllison Tong
Sydney School of Public Health, The University of Sydney, Sydney, NSW 2006, Australia
BMC Nephrol 13:18. 2012..Deceased donor kidneys are a scarce health resource, yet patient preferences for organ allocation are largely unknown. The aim of this study was to determine patient preferences for how kidneys should be allocated for transplantation... - Alcohol consumption and 5-year onset of chronic kidney disease: the AusDiab studySarah L White
The George Institute for International Health, Sydney, Australia
Nephrol Dial Transplant 24:2464-72. 2009..Excessive alcohol consumption is a risk factor for hypertension and stroke; however, evidence for an association with chronic kidney disease is conflicting... - Effects of a fixed combination of perindopril and indapamide in patients with type 2 diabetes and chronic kidney diseaseHiddo J Lambers Heerspink
The George Institute for International Health, University of Sydney, Missenden Road, Camperdown, Sydney, NSW 2050, Australia
Eur Heart J 31:2888-96. 2010..In these analyses of the ADVANCE trial, we assessed the effects of a fixed combination of perindopril-indapamide on renal and cardiovascular outcomes in patients with type 2 diabetes according to baseline CKD stage... - Community attitudes to deceased organ donation: a focus group studyMichelle J Irving
School of Public Health, The University of Sydney, Sydney, NSW, Australia
Transplantation 93:1064-9. 2012..Despite broad community support for organ donation, there is a chronic shortage of donor organs for transplantation. This study elicited community attitudes on deceased organ donation and the current Australian organ donation system... - Gender disparities in the assessment and management of cardiovascular risk in primary care: the AusHEART studyFiona Turnbull
The George Institute for Global Health, University of Sydney, New South Wales, Australia
Eur J Cardiovasc Prev Rehabil 18:498-503. 2011.... - Study Protocol--Improving Access to Kidney Transplants (IMPAKT): a detailed account of a qualitative study investigating barriers to transplant for Australian Indigenous people with end-stage kidney diseaseJeannie Devitt
The George Institute for International Health, PO Box M201, Missenden Road Sydney, NSW, 2050 Australia
BMC Health Serv Res 8:31. 2008.... - The relationship between proteinuria and coronary risk: a systematic review and meta-analysisVlado Perkovic
The George Institute for International Health, Sydney, New South Wales, Australia
PLoS Med 5:e207. 2008..We therefore undertook a systematic review of published cohort studies aiming to provide a reliable estimate of the strength of association between proteinuria and coronary heart disease... - Physical inactivity and chronic kidney disease in Australian adults: the AusDiab studySarah L White
The George Institute for International Health, PO Box M201, Missenden Rd, Camperdown, NSW 2050, Australia Central Clinical School, Faculty of Medicine, University of Sydney, Australia
Nutr Metab Cardiovasc Dis 21:104-12. 2011..We examined the association between leisure-time physical activity and risk of chronic kidney disease in a prospective, population-based cohort of Australians aged ≥ 25 years (AusDiab)... - The risk of cancer in people with diabetes and chronic kidney diseaseGermaine Wong
Centre for Kidney Research and Kids Research Institute, The Children s Hospital at Westmead, Sydney, Australia
Nephrol Dial Transplant 27:3337-44. 2012.... - "All they said was my kidneys were dead": Indigenous Australian patients' understanding of their chronic kidney diseaseKate Anderson
The George Institute for International Health, Sydney, NSW
Med J Aust 189:499-503. 2008..To explore the understanding of both Indigenous and non-Indigenous Australians with end-stage kidney disease (ESKD) about the cause of their disease, and how this understanding could affect patients' engagement with their treatment... - They really want to go back home, they hate it here: the importance of place in Canadian health professionals' views on the barriers facing Aboriginal patients accessing kidney transplantsKate Anderson
The George Institute for International Health and the University of Sydney, PO Box M201, Missenden Road, Camperdown, NSW 2096, Australia
Health Place 15:390-3. 2009..Understanding the role of 'place' as a barrier to accessing care and the lived experiences of Aboriginal patients emerged as key research priorities... - Long-term cancer risk of immunosuppressive regimens after kidney transplantationMartin P Gallagher
Renal Division, George Institute for International Health, Camperdown, New South Wales, Australia
J Am Soc Nephrol 21:852-8. 2010..In conclusion, these immunosuppressive regimens, widely used in recent decades, carry similar risks for carcinogenicity after kidney transplantation... - Gaps in cardiovascular disease risk management in Australian general practiceRuth J Webster
The George Institute for International Health, University of Sydney, Sydney, NSW, Australia
Med J Aust 191:324-9. 2009..To evaluate the management of cardiovascular disease (CVD) risk in Australian general practice... - Intensities of renal replacement therapy in acute kidney injury: a systematic review and meta-analysisMin Jun
The George Institute for International Health, University of Sydney, Sydney, New South Wales, Australia
Clin J Am Soc Nephrol 5:956-63. 2010..A systematic review and meta-analysis was undertaken to assess the effect of different intensities of RRT on all-cause mortality and renal recovery in AKI patients... - Community Preferences for the Allocation & Donation of Organs--the PAraDOx StudyKirsten Howard
School of Public Health, University of Sydney, NSW, 2006, Australia
BMC Public Health 11:386. 2011..Reasons for the chronic shortage of deceased organ donations are unclear; there appears to be no lack of 'in principle' public support for organ donation... - Systematic review: sodium bicarbonate treatment regimens for the prevention of contrast-induced nephropathySophia Zoungas
University of Sydney, Sydney, Australia
Ann Intern Med 151:631-8. 2009..Intravenous sodium bicarbonate has been proposed to reduce the risk for contrast-induced nephropathy (CIN)... - Cyclosporine withdrawal improves long-term graft survival in renal transplantationMartin Gallagher
Renal Division, The George Institute for International Health, Camperdown, NSW, Australia
Transplantation 87:1877-83. 2009..Cyclosporine has been central to immunosuppressive regimens throughout this period but its effect on long-term transplant outcomes remains unclear... - Patient views about treatment of stage 5 CKD: a qualitative analysis of semistructured interviewsRachael L Morton
School of Public Health, University of Sydney, Sydney, Australia
Am J Kidney Dis 55:431-40. 2010.... - The use of psychosocial criteria in Australian patient selection guidelines for kidney transplantationKate Anderson
The George Institute, University of Sydney, Sydney, NSW, Australia
Soc Sci Med 64:2107-14. 2007..The priority given to such criteria in transplant guidelines requires attention and debate... - Proteinuria and stroke: a meta-analysis of cohort studiesToshiharu Ninomiya
The George Institute for International Health, The University of Sydney, Sydney, Australia
Am J Kidney Dis 53:417-25. 2009..We undertook a meta-analysis of published cohort studies to provide a reliable estimate of the strength of association between proteinuria and risk of stroke... - Barriers to access by Indigenous Australians to kidney transplantation: the IMPAKT studyAlan Cass
The George Institute for International Health, Sydney, Australia
Nephrology (Carlton) 9:S144-6. 2004..It will systematically examine each of the steps a new dialysis patient must negotiate in order to receive a transplant. Each of these steps can become a barrier... - New tools for an old trade: a socio-technical appraisal of how electronic decision support is used by primary care practitionersDavid Peiris
The George Institute for Global Health, Sydney, New South Wales, Australia
Sociol Health Illn 33:1002-18. 2011..While EDS tools show promise in improving health practitioner performance, the socio-technical dimensions of their implementation warrant careful consideration... - Community preferences for the allocation of solid organs for transplantation: a systematic reviewAllison Tong
Centre for Kidney Research, The Children s Hospital at Westmead, Sydney, NSW 2145, Australia
Transplantation 89:796-805. 2010..This systematic review aimed to ascertain community preferences for organ allocation and the principles underpinning these preferences... - Building better systems of care for Aboriginal and Torres Strait Islander people: findings from the Kanyini health systems assessmentDavid Peiris
The George Institute for Global Health, University of Sydney, Sydney, Australia
BMC Health Serv Res 12:369. 2012..In this qualitative study we explored Aboriginal Medical Service (AMS) staff views on factors needed to improve chronic care systems and assessed their relevance to the new policy environment... - Hydroxyethyl starch or saline for fluid resuscitation in intensive careJohn A Myburgh
Division of Critical Care and Trauma, George Institute For Global Health, Sydney, NSW, Australia
N Engl J Med 367:1901-11. 2012..The safety and efficacy of hydroxyethyl starch (HES) for fluid resuscitation have not been fully evaluated, and adverse effects of HES on survival and renal function have been reported... - Disparities between prescribing of secondary prevention therapies for stroke and coronary artery disease in general practiceEmma Heeley
The George Institute for Global Health, Royal Prince Alfred Hospital and University of Sydney, Sydney, NSW, Australia
Int J Stroke 7:649-54. 2012..Extensive evidence exists regarding the effectiveness of secondary prevention measures in patients with cardiovascular disease... - Rationale and design of the Kanyini guidelines adherence with the polypill (Kanyini-GAP) study: a randomised controlled trial of a polypill-based strategy amongst indigenous and non indigenous people at high cardiovascular riskHueiming Liu
The George Institute for International Health, PO Box M201, Missenden Road, NSW 2050, Australia
BMC Public Health 10:458. 2010.... - Intensive glycemic control and renal outcomeMin Jun
Renal and Metabolic Division, The George Institute for Global Health, Sydney Medical School, University of Sydney, Camperdown, NSW, Australia
Contrib Nephrol 170:196-208. 2011..Until further data are available, an individualized approach to glucose management is recommended in people with reduced glomerular filtration rate... - Applying evidence into routine clinical care at a unit level: the exemplar of renal anaemia managementMartin P Gallagher
The George Institute for International Health, Renal Division, PO Box 201, Missenden Road, Camperdown, NSW 2050, Australia
Nephrology (Carlton) 15:429-33. 2010..Measurement against an agreed standard is fundamental to this process. We use the example of renal anaemia management across a dialysis unit to illustrate an approach to these issues... - Effects of fibrates on cardiovascular outcomes: a systematic review and meta-analysisMin Jun
The George Institute for International Health, University of Sydney, Sydney, Australia
Lancet 375:1875-84. 2010..Several clinical trials have reported inconsistent findings for the effect of fibrates on cardiovascular risk. We undertook a systematic review and meta-analysis to investigate the effects of fibrates on major clinical outcomes... - Survival of elderly dialysis patients is predicted by both patient and practice characteristicsCeline Foote
Renal and Metabolic Division, The George Institute for Global Health, Sydney, Australia
Nephrol Dial Transplant 27:3581-7. 2012..Improved understanding of contemporary patient and practice factors influencing prognosis may assist decision making for individual patients and their care providers... - Effects of fibrates in kidney disease: a systematic review and meta-analysisMin Jun
George Institute For Global Health, The University of Sydney, Sydney, New South Wales, Australia
J Am Coll Cardiol 60:2061-71. 2012..The purpose of this systematic review and meta-analysis was to determine the efficacy and safety of fibrate therapy in the chronic kidney disease (CKD) population... - Cardiovascular disease risk management for Aboriginal and Torres Strait Islander peoples in primary health care settings: findings from the Kanyini AuditDavid P Peiris
The George Institute for International Health, University of Sydney, Sydney, NSW, Australia
Med J Aust 191:304-9. 2009..To describe cardiovascular disease (CVD) risk management in Indigenous primary health care... - Socioeconomic disadvantage and kidney disease in the United States, Australia, and ThailandSarah L White
George Institute, Sydney, NSW, Australia
Am J Public Health 98:1306-13. 2008..We sought to determine whether an elevated burden of chronic kidney disease is found among disadvantaged groups living in the United States, Australia, and Thailand... - Effect of lowering blood pressure on cardiovascular events and mortality in patients on dialysis: a systematic review and meta-analysis of randomised controlled trialsHiddo J Lambers Heerspink
George Institute for International Health, University of Sydney, Sydney, Australia
Lancet 373:1009-15. 2009..We did a systematic review and meta-analysis to assess the effect of blood pressure lowering in patients on dialysis... - Cardiovascular risk perception and evidence--practice gaps in Australian general practice (the AusHEART study)Emma L Heeley
The George Institute for International Health, Sydney, NSW, Australia
Med J Aust 192:254-9. 2010..To examine the perception and management of cardiovascular disease (CVD) risk in Australian primary care... - How can we achieve global equity in provision of renal replacement therapy?Sarah L White
The George Institute for International Health, Royal Prince Alfred Hospital, Missenden Road, Sydney, NSW, Australia
Bull World Health Organ 86:229-37. 2008..Prevention of end-stage kidney disease, ideally as part of an integrated approach to chronic vascular diseases, must also be a key objective... - Robust data to close the gap: current vascular and maternal/newborn indicators as measures of progress in Aboriginal health in New South WalesDavid Peiris
The George Institute for International Health, University of Sydney, New South Wales
Aust N Z J Public Health 34:563-71. 2010..Focussing on maternal/newborn health and vascular diseases, to review NSW Health's reporting, by Aboriginal status, against national performance indicators relevant to preventable chronic diseases... - Is low birth weight an antecedent of CKD in later life? A systematic review of observational studiesSarah L White
The George Institute, Faculty of Medicine, University of Sydney, Sydney, Australia
Am J Kidney Dis 54:248-61. 2009..There has been considerable interest in the hypothesis that low birth weight may be a marker of impaired nephrogenesis and that this is causally related to chronic kidney disease (CKD)... - Blood pressure is a major risk factor for renal death: an analysis of 560 352 participants from the Asia-Pacific regionConall M O'Seaghdha
George Institute for International Health, Royal Prince Alfred Hospital, Missenden Road, Camperdown, Sydney, New South Wales 2050, Australia
Hypertension 54:509-15. 2009..10). The results were similar for cohorts in Asia and Australia. These results suggest that primary prevention strategies for renal disease should focus on individuals with elevated blood pressure, diabetes mellitus, and dyslipidemia... - The cost-effectiveness of increasing kidney transplantation and home-based dialysisKirsten Howard
University of Sydney, Australia
Nephrology (Carlton) 14:123-32. 2009..We aimed to quantify these implications for increasing kidney transplantation and improving the rate of home-based dialysis... - Addressing inequities in access to quality health care for indigenous peopleDavid Peiris
George Institute for International Health, New South Wales, Australia
CMAJ 179:985-6. 2008 - Limited knowledge of kidney disease in a survey of AusDiab study participantsSarah L White
Renal Division, The George Institute, Sydney, NSW, Australia
Med J Aust 188:204-8. 2008..To explore awareness of the causes of kidney disease and recollection of kidney function testing in a cohort of Australian adults... - Health outcomes in Aboriginal populationsAlan Cass
The George Institute for International Health, Sydney, Australia
CMAJ 171:597-8. 2004 - Albuminuria and kidney function independently predict cardiovascular and renal outcomes in diabetesToshiharu Ninomiya
George Institute for International Health, University of Sydney, Sydney, NSW, Australia
J Am Soc Nephrol 20:1813-21. 2009..In conclusion, high albuminuria and low eGFR are independent risk factors for cardiovascular and renal events among patients with type 2 diabetes... - Chronic kidney disease, cardiovascular events, and the effects of perindopril-based blood pressure lowering: data from the PROGRESS studyVlado Perkovic
George Institute for International Health, PO Box M201, Sydney, Australia, 2050
J Am Soc Nephrol 18:2766-72. 2007..In conclusion, kidney function should be considered when determining the need for blood pressure lowering therapy in patients with cerebrovascular disease... - The RENAL (Randomised Evaluation of Normal vs. Augmented Level of Replacement Therapy) study: statistical analysis planSimon Finfer
The George Institute for International Health, Sydney, NSW
Crit Care Resusc 11:58-66. 2009..The Randomised Evaluation of Normal vs. Augmented Level of Replacement Therapy (RENAL) study is the largest interventional trial ever conducted in patients with acute renal failure... - Kidney disease: are you at risk?Alan Cass
Med J Aust 176:515-6. 2002 - End-stage renal disease in indigenous Australians: a disease of disadvantageAlan Cass
Menzies School of Health Research, Casuarina, NT, Australia
Ethn Dis 12:373-8. 2002..To determine the relation between area level indicators of socioeconomic disadvantage and the regional incidence of end-stage renal disease (ESRD) in indigenous Australians... - Delayed referral to a nephrologist: outcomes among patients who survive at least one year on dialysisAlan Cass
Menzies School of Health Research, PO Box 41096, Casuarina, NT 0811, Australia
Med J Aust 177:135-8. 2002..To investigate whether late referral to a nephrologist of patients with chronic renal insufficiency influences the likelihood of both transplantation and mortality among those who survive at least one year on dialysis... - The relationship between the incidence of end-stage renal disease and markers of socioeconomic disadvantageAlan Cass
Menzies School of Health Research, Darwin, Northern Territory
N S W Public Health Bull 13:147-51. 2002 - Urban disadvantage and delayed nephrology referral in AustraliaAlan Cass
Menzies School of Health Research, P O Box 41096, Casuarina, NT 0811, Australia
Health Place 9:175-82. 2003..This may indicate inequitable access to optimal pre-ESRD care... - Access to renal transplantation among American Indians and HispanicsThomas D Sequist
Department of Health Care Policy, Harvard Medical School, Boston, MA, USA
Am J Kidney Dis 44:344-52. 2004..Policies to address these disparities should address specific barriers within the transplant evaluation process... - Late referral to a nephrologist reduces access to renal transplantationAlan Cass
Department of Health Care Policy, Harvard Medical School, Boston, MA 02115, USA
Am J Kidney Dis 42:1043-9. 2003..Late referral is associated with higher morbidity and worse long-term survival rates. The authors examined the effect of late referral on access to renal transplantation... - Renal transplantation for Indigenous Australians: identifying the barriers to equitable accessAlan Cass
Menzies School of Health Research, Cooperative Research Centre for Aboriginal and Tropical Health, Casuarina, Northern Territory, Australia
Ethn Health 8:111-9. 2003..To examine whether disparities are due to a lower rate of acceptance onto the waiting list and/or a lower rate of moving from the list to transplantation... - Exploring the pathways leading from disadvantage to end-stage renal disease for indigenous AustraliansAlan Cass
Menzies School of Health Research, PO Box 41096, Darwin, Casarina NT 0811, Australia
Soc Sci Med 58:767-85. 2004.... - Trends in the incidence of treated end-stage kidney disease among Indigenous Australians and access to treatmentAnnie Preston-Thomas
WuChopperen Health Service, Cairns, Queensland
Aust N Z J Public Health 31:419-21. 2007..To determine temporal trends of incidence of treated end-stage kidney disease in Indigenous Australians and the extent to which these patients had to move from their home community to access renal replacement therapy... - Australian nephrologists' attitudes towards living kidney donationJoan Cunningham
Nephrol Dial Transplant 21:1178-83. 2006..Meeting the growing demand for kidney transplantation will require an increased supply of both live and deceased donor kidneys. We should develop, evaluate and implement best-practice approaches to achieve this... - Access to renal transplantation for minority patients with ESRD in CanadaKaren E Yeates
Division of Nephrology, Queen s University, Kingston, Ontario, Canada
Am J Kidney Dis 44:1083-9. 2004..It is unknown whether similar differences exist in Canada... - Cause of death in patients with end-stage renal disease: assessing concordance of death certificates with registry reportsShu Qin Li
Northern Territory Department of Health and Community Services, Northern Territory University
Aust N Z J Public Health 27:419-24. 2003..Information from these sources was not directly comparable. Neither dataset provided a complete picture of renal disease as a cause of death in Australia... - Bridging the treatment gap for Indigenous Australians. Demands for efficiency should not be met at the expense of equityJoan Cunningham
Med J Aust 182:505-6. 2005..Demands for efficiency should not be met at the expense of equity...