Victor A Streltsov

Summary

Country: Australia

Publications

  1. ncbi request reprint Structure of the haemagglutinin-neuraminidase from human parainfluenza virus type III
    Michael C Lawrence
    CSIRO Health Sciences and Nutrition, 343 Royal Parade, Parkville, VIC 3052, Australia
    J Mol Biol 335:1343-57. 2004
  2. pmc The structure of the amyloid-beta peptide high-affinity copper II binding site in Alzheimer disease
    Victor A Streltsov
    Commonwealth Scientific Industrial Research Organization Molecular and Health Technologies, and Preventative Health Flagship, Parkville, Victoria 3052, Australia
    Biophys J 95:3447-56. 2008
  3. ncbi request reprint Structural insights into the interaction of platinum-based inhibitors with the Alzheimer's disease amyloid-β peptide
    Victor A Streltsov
    CSIRO Materials Science and Engineering and Preventative Health Flagship, Parkville, Victoria 3052, Australia
    Chem Commun (Camb) 49:11364-6. 2013
  4. ncbi request reprint Haloalkane dehalogenase LinB from Sphingomonas paucimobilis UT26: X-ray crystallographic studies of dehalogenation of brominated substrates
    Victor A Streltsov
    Crystallography Centre, School of Biomedical and Chemical Sciences, University of Western Australia, 35 Stirling Highway, Crawley 6009, Western Australia, Australia
    Biochemistry 42:10104-12. 2003
  5. doi request reprint Crystal structure of the amyloid-β p3 fragment provides a model for oligomer formation in Alzheimer's disease
    Victor A Streltsov
    Commonwealth Scientific and Industrial Research Organization, Parkville, Victoria 3052, Australia
    J Neurosci 31:1419-26. 2011
  6. ncbi request reprint X-ray absorption and diffraction studies of the metal binding sites in amyloid beta-peptide
    Victor Streltsov
    CSIRO Molecular and Health Technologies, 343 Royal Parade, Parkville, Vic, Australia
    Eur Biophys J 37:257-63. 2008
  7. ncbi request reprint Crystal structure study of a beta'-copper vanadium bronze, Cu(x)V2O5 (x = 0.63), by X-ray and convergent beam electron diffraction
    Victor A Streltsov
    CSIRO HSN, 343 Royal Parade, Parkville, Victoria 3052, Australia
    Acta Crystallogr B 61:17-24. 2005
  8. pmc Structure of a shark IgNAR antibody variable domain and modeling of an early-developmental isotype
    Victor A Streltsov
    CSIRO Molecular and Health Technologies, 343 Royal Parade, Parkville, Victoria 3052, Australia
    Protein Sci 14:2901-9. 2005
  9. ncbi request reprint Structure of an IgNAR-AMA1 complex: targeting a conserved hydrophobic cleft broadens malarial strain recognition
    Kylie A Henderson
    CSIRO Molecular and Health Technologies, 343 Royal Parade, Parkville 3052, Australia
    Structure 15:1452-66. 2007
  10. ncbi request reprint Shark IgNAR antibody mimotopes target a murine immunoglobulin through extended CDR3 loop structures
    David P Simmons
    CSIRO Division of Molecular and Health Technologies, Parkville, Victoria 3052, Australia
    Proteins 71:119-30. 2008

Collaborators

Detail Information

Publications24

  1. ncbi request reprint Structure of the haemagglutinin-neuraminidase from human parainfluenza virus type III
    Michael C Lawrence
    CSIRO Health Sciences and Nutrition, 343 Royal Parade, Parkville, VIC 3052, Australia
    J Mol Biol 335:1343-57. 2004
    ..However, in contrast to the NDV structures, we observe no ligand-induced structural changes that extend beyond the active site and modify the dimer interface...
  2. pmc The structure of the amyloid-beta peptide high-affinity copper II binding site in Alzheimer disease
    Victor A Streltsov
    Commonwealth Scientific Industrial Research Organization Molecular and Health Technologies, and Preventative Health Flagship, Parkville, Victoria 3052, Australia
    Biophys J 95:3447-56. 2008
    ..The structure of the high-affinity Cu(2+) binding site is consistent with the hypothesis that the redox activity of the metal ion bound to Abeta can lead to the formation of dityrosine-linked dimers found in AD...
  3. ncbi request reprint Structural insights into the interaction of platinum-based inhibitors with the Alzheimer's disease amyloid-β peptide
    Victor A Streltsov
    CSIRO Materials Science and Engineering and Preventative Health Flagship, Parkville, Victoria 3052, Australia
    Chem Commun (Camb) 49:11364-6. 2013
    ....
  4. ncbi request reprint Haloalkane dehalogenase LinB from Sphingomonas paucimobilis UT26: X-ray crystallographic studies of dehalogenation of brominated substrates
    Victor A Streltsov
    Crystallography Centre, School of Biomedical and Chemical Sciences, University of Western Australia, 35 Stirling Highway, Crawley 6009, Western Australia, Australia
    Biochemistry 42:10104-12. 2003
    ..This also leads to slight contraction of the whole complex structures. The flexibility detected by crystallographic analysis is in remarkable agreement with flexibility observed by molecular dynamic simulations...
  5. doi request reprint Crystal structure of the amyloid-β p3 fragment provides a model for oligomer formation in Alzheimer's disease
    Victor A Streltsov
    Commonwealth Scientific and Industrial Research Organization, Parkville, Victoria 3052, Australia
    J Neurosci 31:1419-26. 2011
    ....
  6. ncbi request reprint X-ray absorption and diffraction studies of the metal binding sites in amyloid beta-peptide
    Victor Streltsov
    CSIRO Molecular and Health Technologies, 343 Royal Parade, Parkville, Vic, Australia
    Eur Biophys J 37:257-63. 2008
    ..This review provides a blend of X-ray diffraction results on amyloid structures and selected works on A beta Cu2+ binding based on spectroscopic measurements with emphasis on the X-ray absorption technique...
  7. ncbi request reprint Crystal structure study of a beta'-copper vanadium bronze, Cu(x)V2O5 (x = 0.63), by X-ray and convergent beam electron diffraction
    Victor A Streltsov
    CSIRO HSN, 343 Royal Parade, Parkville, Victoria 3052, Australia
    Acta Crystallogr B 61:17-24. 2005
    ..038 and z=0.357. The crystal structure changes little with temperature. Disorder of the Cu ion over two sites is seen at 9.6 K. This suggests that distribution of the Cu atoms over two sites is of a more static than dynamic nature...
  8. pmc Structure of a shark IgNAR antibody variable domain and modeling of an early-developmental isotype
    Victor A Streltsov
    CSIRO Molecular and Health Technologies, 343 Royal Parade, Parkville, Victoria 3052, Australia
    Protein Sci 14:2901-9. 2005
    ....
  9. ncbi request reprint Structure of an IgNAR-AMA1 complex: targeting a conserved hydrophobic cleft broadens malarial strain recognition
    Kylie A Henderson
    CSIRO Molecular and Health Technologies, 343 Royal Parade, Parkville 3052, Australia
    Structure 15:1452-66. 2007
    ..These findings provide insights into mechanisms of single-domain antibody binding, and may enable design of reagents targeting otherwise cryptic epitopes in pathogen antigens...
  10. ncbi request reprint Shark IgNAR antibody mimotopes target a murine immunoglobulin through extended CDR3 loop structures
    David P Simmons
    CSIRO Division of Molecular and Health Technologies, Parkville, Victoria 3052, Australia
    Proteins 71:119-30. 2008
    ....
  11. ncbi request reprint The insulin and EGF receptor structures: new insights into ligand-induced receptor activation
    Colin W Ward
    Australian Commonwealth Scientific and Research Organization Molecular and Health Technologies, 343 Royal Parade, Parkville, Victoria 3052, Australia
    Trends Biochem Sci 32:129-37. 2007
    ..This is very different from the folded-over (tethered) conformation of the unactivated EGFR and provides insight into the potential mechanism of activation of the IR...
  12. doi request reprint Structural studies of the tethered N-terminus of the Alzheimer's disease amyloid-β peptide
    Rebecca M Nisbet
    Materials Science and Engineering and Preventative Health Flagship, CSIRO, Parkville, Victoria, 3052, Australia
    Proteins 81:1748-58. 2013
    ....
  13. ncbi request reprint Structure of the insulin receptor ectodomain reveals a folded-over conformation
    Neil M McKern
    CSIRO Molecular and Health Technologies, 343 Royal Parade, Parkville, Victoria 3052, Australia
    Nature 443:218-21. 2006
    ..Instead, the structure implicates the carboxy-terminal surface of the first fibronectin type III domain as the second binding site involved in high-affinity binding...
  14. pmc Germline humanization of a murine Abeta antibody and crystal structure of the humanized recombinant Fab fragment
    Remy Robert
    CSIRO Molecular and Health Technologies, 343 Royal Parade, Parkville, Victoria 3052, Australia
    Protein Sci 19:299-308. 2010
    ..This humanized version retains a high affinity for the Abeta peptide and therefore is a potential candidate for passive immunotherapy of Alzheimer's disease...
  15. ncbi request reprint Dimerisation strategies for shark IgNAR single domain antibody fragments
    David P Simmons
    CRC for Diagnostics, Parkville, Victoria 3052, Australia
    J Immunol Methods 315:171-84. 2006
    ....
  16. pmc Structural and functional basis of resistance to neuraminidase inhibitors of influenza B viruses
    Aaron J Oakley
    CSIRO Materials Science and Engineering, Parkville, 343 Royal Parade, Parkville, Victoria, 3052, Australia
    J Med Chem 53:6421-31. 2010
    ..Lack of the E275 rotation would also account for the loss of slow binding and the partial resistance of influenza B wild type NAs to oseltamivir...
  17. ncbi request reprint In vitro improvement of a shark IgNAR antibody by Qbeta replicase mutation and ribosome display mimics in vivo affinity maturation
    George Kopsidas
    EvoGenix Limited, 343 Royal Parade, Parkville, VIC 3052, Australia
    Immunol Lett 107:163-8. 2006
    ....
  18. doi request reprint Oligomerization and toxicity of Aβ fusion proteins
    Joanne M Caine
    CSIRO Materials Science and Engineering and the Preventive Health Flagship, Parkville, Victoria, Australia
    Biochem Biophys Res Commun 409:477-82. 2011
    ..This study demonstrates the potential utility of MBP-Aβ42 as a reagent for drug screening assays in yeast and neuronal cell cultures and as a candidate for further Aβ42 characterization...
  19. doi request reprint Isolation, kinetic analysis, and structural characterization of an antibody targeting the Bacillus anthracis major spore surface protein BclA
    Stewart D Nuttall
    CSIRO Division of Materials Science and Engineering, Parkville, Victoria, 3052, Australia
    Proteins 79:1306-17. 2011
    ....
  20. doi request reprint In vitro passaging of a pandemic H1N1/09 virus selects for viruses with neuraminidase mutations conferring high-level resistance to oseltamivir and peramivir, but not to zanamivir
    Jennifer L McKimm-Breschkin
    CSIRO Materials Science and Engineering, Parkville, Australia 3052
    J Antimicrob Chemother 67:1874-83. 2012
    ..We also wanted to investigate if passaging in a combination of zanamivir and oseltamivir could prevent the emergence of the H274Y mutation...
  21. ncbi request reprint Unprecedented conformational flexibility revealed in the ligand-binding domains of the Bovicola ovis ecdysone receptor (EcR) and ultraspiracle (USP) subunits
    Bin Ren
    CSIRO Materials Science and Engineering, 343 Royal Parade, Parkville, VIC 3052, Australia
    Acta Crystallogr D Biol Crystallogr 70:1954-64. 2014
    ..Interestingly, the new USP conformation presents an open, unoccupied ligand-binding pocket. ..
  22. pmc Ammonium hydroxide treatment of Aβ produces an aggregate free solution suitable for biophysical and cell culture characterization
    Timothy M Ryan
    The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Victoria, Australia
    Peerj 1:e73. 2013
    ..These techniques for solubilising and controlling the oligomeric state of Aβ are valuable starting points for future biophysical and toxicity assays...
  23. ncbi request reprint Construction, crystal structure and application of a recombinant protein that lacks the collagen-like region of BclA from Bacillus anthracis spores
    Chun Qiang Liu
    DSTO Human Protection and Performance Division, 506 Lorimer Street, Fishermans Bend, Melbourne, Victoria 3207, Australia
    Biotechnol Bioeng 99:774-82. 2008
    ..anthracis spores. Biotechnol. Bioeng. 2008;99: 774-782. (c) 2007 Wiley Periodicals, Inc...
  24. ncbi request reprint Structural rationale for low-nanomolar binding of transition state mimics to a family GH3 beta-D-glucan glucohydrolase from barley
    Maria Hrmova
    School of Agriculture and Wine and Australian Centre for Plant Functional Genomics, University of Adelaide, Waite Campus, Glen Osmond, SA 5064, Australia
    Biochemistry 44:16529-39. 2005
    ..Finally, the high-resolution structures enabled us to define minimal structures of oligosaccharides attached to Asn221, Asn498, and Asn600 N-glycosylation sites...