Nora E Straznicky

Summary

Country: Australia

Publications

  1. pmc Weight loss may reverse blunted sympathetic neural responsiveness to glucose ingestion in obese subjects with metabolic syndrome
    Nora E Straznicky
    Human Neurotransmitters Laboratory, Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, Australia
    Diabetes 58:1126-32. 2009
  2. ncbi request reprint Neuroadrenergic dysfunction in obesity: an overview of the effects of weight loss
    Nora E Straznicky
    Human Neurotransmitters Laboratory, Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, Australia
    Curr Opin Lipidol 21:21-30. 2010
  3. doi request reprint The effects of weight loss versus weight loss maintenance on sympathetic nervous system activity and metabolic syndrome components
    Nora E Straznicky
    Laboratories of Human Neurotransmitters, Baker IDI Heart and Diabetes Institute, P O Box 6492, St Kilda Road Central, Melbourne, Victoria 8008, Australia
    J Clin Endocrinol Metab 96:E503-8. 2011
  4. doi request reprint The relation of glucose metabolism to left ventricular mass and function and sympathetic nervous system activity in obese subjects with metabolic syndrome
    Nora E Straznicky
    Laboratories of Human Neurotransmitters, Baker IDI Heart and Diabetes Institute, PO Box 6492, St Kilda Road Central, Melbourne, Victoria, Australia a
    J Clin Endocrinol Metab 98:E227-37. 2013
  5. pmc Neuroadrenergic dysfunction along the diabetes continuum: a comparative study in obese metabolic syndrome subjects
    Nora E Straznicky
    Laboratory of Human Neurotransmitters, Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, Australia
    Diabetes 61:2506-16. 2012
  6. doi request reprint The effects of dietary weight loss with or without exercise training on liver enzymes in obese metabolic syndrome subjects
    N E Straznicky
    Laboratories of Human Neurotransmitters, Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, Australia
    Diabetes Obes Metab 14:139-48. 2012
  7. doi request reprint Baseline sympathetic nervous system activity predicts dietary weight loss in obese metabolic syndrome subjects
    Nora E Straznicky
    Laboratory of Human Neurotransmitters, Baker IDI Heart and Diabetes Institute, P O Box 6492, St Kilda Road Central, Melbourne, Victoria 8008, Australia
    J Clin Endocrinol Metab 97:605-13. 2012
  8. doi request reprint Exercise augments weight loss induced improvement in renal function in obese metabolic syndrome individuals
    Nora E Straznicky
    Baker IDI Heart and Diabetes Institute, P O Box 6492, St Kilda Road Central, Melbourne, VIC 8008, Australia
    J Hypertens 29:553-64. 2011
  9. pmc Sympathetic neural adaptation to hypocaloric diet with or without exercise training in obese metabolic syndrome subjects
    Nora E Straznicky
    Human Neurotransmitters Laboratory, Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, Australia
    Diabetes 59:71-9. 2010
  10. doi request reprint Blunted sympathetic neural response to oral glucose in obese subjects with the insulin-resistant metabolic syndrome
    Nora E Straznicky
    Human Neurotransmitters and Heart Failure Division, Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, Australia
    Am J Clin Nutr 89:27-36. 2009

Detail Information

Publications20

  1. pmc Weight loss may reverse blunted sympathetic neural responsiveness to glucose ingestion in obese subjects with metabolic syndrome
    Nora E Straznicky
    Human Neurotransmitters Laboratory, Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, Australia
    Diabetes 58:1126-32. 2009
    ..The purpose of this study was to examine the effects of weight loss on sympathetic nervous system responsiveness to glucose ingestion in obese subjects with metabolic syndrome, in whom such responses are reportedly blunted...
  2. ncbi request reprint Neuroadrenergic dysfunction in obesity: an overview of the effects of weight loss
    Nora E Straznicky
    Human Neurotransmitters Laboratory, Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, Australia
    Curr Opin Lipidol 21:21-30. 2010
    ..Weight loss is recommended as first-line treatment for obesity. This review examines the effects of nonpharmacological weight loss on sympathetic nervous system function under basal and stimulated conditions...
  3. doi request reprint The effects of weight loss versus weight loss maintenance on sympathetic nervous system activity and metabolic syndrome components
    Nora E Straznicky
    Laboratories of Human Neurotransmitters, Baker IDI Heart and Diabetes Institute, P O Box 6492, St Kilda Road Central, Melbourne, Victoria 8008, Australia
    J Clin Endocrinol Metab 96:E503-8. 2011
    ..Sympathetic nervous system (SNS) overactivity participates in both the pathogenesis and adverse clinical complications of metabolic syndrome (MetS) obesity...
  4. doi request reprint The relation of glucose metabolism to left ventricular mass and function and sympathetic nervous system activity in obese subjects with metabolic syndrome
    Nora E Straznicky
    Laboratories of Human Neurotransmitters, Baker IDI Heart and Diabetes Institute, PO Box 6492, St Kilda Road Central, Melbourne, Victoria, Australia a
    J Clin Endocrinol Metab 98:E227-37. 2013
    ..Altered cardiac structure and function have been reported in prediabetic and diabetic populations; however, the contribution of the sympathetic nervous system (SNS) to these changes has yet to be delineated...
  5. pmc Neuroadrenergic dysfunction along the diabetes continuum: a comparative study in obese metabolic syndrome subjects
    Nora E Straznicky
    Laboratory of Human Neurotransmitters, Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, Australia
    Diabetes 61:2506-16. 2012
    ..35, P = 0.047). These findings demonstrate that progression to T2D is associated with increased central sympathetic drive, blunted sympathetic responsiveness, and altered norepinephrine disposition...
  6. doi request reprint The effects of dietary weight loss with or without exercise training on liver enzymes in obese metabolic syndrome subjects
    N E Straznicky
    Laboratories of Human Neurotransmitters, Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, Australia
    Diabetes Obes Metab 14:139-48. 2012
    ....
  7. doi request reprint Baseline sympathetic nervous system activity predicts dietary weight loss in obese metabolic syndrome subjects
    Nora E Straznicky
    Laboratory of Human Neurotransmitters, Baker IDI Heart and Diabetes Institute, P O Box 6492, St Kilda Road Central, Melbourne, Victoria 8008, Australia
    J Clin Endocrinol Metab 97:605-13. 2012
    ..The sympathetic nervous system is an important physiological modulator of basal and postprandial energy expenditure...
  8. doi request reprint Exercise augments weight loss induced improvement in renal function in obese metabolic syndrome individuals
    Nora E Straznicky
    Baker IDI Heart and Diabetes Institute, P O Box 6492, St Kilda Road Central, Melbourne, VIC 8008, Australia
    J Hypertens 29:553-64. 2011
    ..This study was conducted to examine the effects of lifestyle interventions on renal parameters and putative metabolic, neuroadrenergic and hemodynamic mediators of renal injury...
  9. pmc Sympathetic neural adaptation to hypocaloric diet with or without exercise training in obese metabolic syndrome subjects
    Nora E Straznicky
    Human Neurotransmitters Laboratory, Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, Australia
    Diabetes 59:71-9. 2010
    ..This study was conducted to examine the effects of lifestyle interventions (weight loss alone or together with exercise) on SNS function...
  10. doi request reprint Blunted sympathetic neural response to oral glucose in obese subjects with the insulin-resistant metabolic syndrome
    Nora E Straznicky
    Human Neurotransmitters and Heart Failure Division, Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, Australia
    Am J Clin Nutr 89:27-36. 2009
    ..Glucose ingestion stimulates sympathetic nervous system (SNS) activity in lean subjects, whereas blunted responses have been reported in the obese...
  11. ncbi request reprint Mediators of sympathetic activation in metabolic syndrome obesity
    Nora E Straznicky
    Human Neurotransmitters Laboratory, Baker IDI Heart and Diabetes Institute, Melbourne, Victoria 8008, Australia
    Curr Hypertens Rep 10:440-7. 2008
    ..Because chronic sympathetic activation contributes to hypertension and its target-organ damage, sympathoinhibition remains an important goal in the therapeutic management of the metabolic syndrome...
  12. ncbi request reprint Effects of dietary weight loss on sympathetic activity and cardiac risk factors associated with the metabolic syndrome
    Nora E Straznicky
    Cardiovascular Nutrition Laboratory, Wynn Domain, Baker Heart Research Institute, P O Box 6492, St Kilda Road Central, Melbourne, Victoria 8008, Australia
    J Clin Endocrinol Metab 90:5998-6005. 2005
    ....
  13. ncbi request reprint Leptin-receptor polymorphisms relate to obesity through blunted leptin-mediated sympathetic nerve activation in a Caucasian male population
    Kazuko Masuo
    Human Neurotransmitter Laboratory, Baker Heart Research Institute, Melbourne, Australia
    Hypertens Res 31:1093-100. 2008
    ..We therefore hypothesize that leptin-receptor play a role in the development of obesity through leptin resistance and blunted leptin-mediated sympathetic nerve activity...
  14. doi request reprint Sympathetic nervous activation in obesity and the metabolic syndrome--causes, consequences and therapeutic implications
    Gavin W Lambert
    Human Neurotransmitters Laboratory, Baker IDI Heart and Diabetes Institute, Melbourne, Australia
    Pharmacol Ther 126:159-72. 2010
    ..Importantly, the benefit may not necessarily be weight related but may be associated with a reduction in end organ damage...
  15. ncbi request reprint The effects of dietary weight loss on indices of norepinephrine turnover: modulatory influence of hyperinsulinemia
    Nora E Straznicky
    Laboratories of Human Neurotransmitters, Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, Australia
    Obesity (Silver Spring) 22:652-62. 2014
    ..This study was conducted to examine (1) the effects of dietary weight loss on indices of norepinephrine (NE) turnover and (2) whether baseline hyperinsulinemia modulates sympathetic neural adaptations...
  16. ncbi request reprint Surgical approaches to the treatment of obesity
    John B Dixon
    Baker IDI Heart and Diabetes Institute, PO Box 6492 St Kilda Road Central, Melbourne, VIC 3004, Australia
    Nat Rev Gastroenterol Hepatol 8:429-37. 2011
    ..Gastroenterologists also need to be familiar with the risks and benefits of current and emerging procedures as they are likely to be increasingly involved in the integrated care of these patients...
  17. pmc The effects of exercise training in addition to energy restriction on functional capacities and body composition in obese adults during weight loss: a systematic review
    Clint T Miller
    Centre for Exercise and Sports Science, School of Exercise and Nutrition Sciences, Deakin University, Melbourne, Australia
    PLoS ONE 8:e81692. 2013
    ..This review examines the specific effects of exercise training in relation to body composition and physical function demonstrated by changes in cardiovascular fitness, and muscle strength when obese adults undergo energy restriction...
  18. doi request reprint A sympathetic view of human obesity
    Elisabeth A Lambert
    Human Neurotransmitters Laboratory, Baker IDI Heart and Diabetes Institute, Melbourne, Vic, Australia
    Clin Auton Res 23:9-14. 2013
    ..Targeting the SNS may be an attractive and important avenue for the pharmacological treatment of obesity-related disturbances...
  19. pmc Predicting the glycemic response to gastric bypass surgery in patients with type 2 diabetes
    John B Dixon
    Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, Australia
    Diabetes Care 36:20-6. 2013
    ..Predicting the improvement in glycemic control in those with type 2 diabetes after bariatric surgery may help in patient selection...