A Keogh

Summary

Affiliation: St Vincent's Hospital
Country: Australia

Publications

  1. ncbi Public funding of bosentan for the treatment of pulmonary artery hypertension in Australia: cost effectiveness and risk sharing
    John H Wlodarczyk
    John Wlodarczyk Consulting Services, New Lambton, New South Wales, Australia
    Pharmacoeconomics 24:903-15. 2006
  2. ncbi Quality of life in pulmonary arterial hypertension: improvement and maintenance with bosentan
    Anne M Keogh
    Victor Chang Research Institute, St Vincent s Hospital, Sydney, Australia
    J Heart Lung Transplant 26:181-7. 2007
  3. pmc Hemodynamics in pulmonary arterial hypertension (PAH): do they explain long-term clinical outcomes with PAH-specific therapy?
    Peter Steele
    Department of Epidemiology and Preventative Medicine, Monash University, Melbourne, Vic, Australia
    BMC Cardiovasc Disord 10:9. 2010
  4. ncbi Sirolimus in de novo heart transplant recipients reduces acute rejection and prevents coronary artery disease at 2 years: a randomized clinical trial
    Anne Keogh
    St Vincent s Hospital, Xavier 4, Victoria St, Darlinghurst, Sydney, New South Wales 2010, Australia
    Circulation 110:2694-700. 2004
  5. ncbi Long-term benefits of mycophenolate mofetil after heart transplantation
    Anne Keogh
    Heart Transplant Unit, St Vincent s Hospital, Sydney, Australia
    Transplantation 79:S45-6. 2005
  6. ncbi Improving outcomes in heart transplantation: the potential of proliferation signal inhibitors
    A Keogh
    Heart and Lung Transplant Unit, St Vincent s Hospital, Sydney, Australia
    Transplant Proc 37:1S-3S. 2005
  7. ncbi Calcineurin inhibitors in heart transplantation
    Anne Keogh
    Victor Chang Cardiac Research Institute and Heart Lung Transplant Unit, St Vincent s Hospital, Darlinghurst, New South Wales, Australia
    J Heart Lung Transplant 23:S202-6. 2004
  8. ncbi Pulmonary arterial hypertension: a new era in management
    Anne M Keogh
    Xavier 4, St Vincent s Hospital, Victoria Street, Darlinghurst, NSW 2010, Australia
    Med J Aust 178:564-7. 2003
  9. ncbi Interventional and surgical modalities of treatment in pulmonary hypertension
    Anne M Keogh
    St Vincent s Hospital, Sydney, NSW, Australia
    J Am Coll Cardiol 54:S67-77. 2009
  10. doi The Bosentan Patient Registry: long-term survival in pulmonary arterial hypertension
    A Keogh
    St Vincent s Hospital, Sydney, John Wlodarczyk Consulting Services, Newcastle, New South Wales, Australia
    Intern Med J 41:227-34. 2011

Collaborators

Detail Information

Publications31

  1. ncbi Public funding of bosentan for the treatment of pulmonary artery hypertension in Australia: cost effectiveness and risk sharing
    John H Wlodarczyk
    John Wlodarczyk Consulting Services, New Lambton, New South Wales, Australia
    Pharmacoeconomics 24:903-15. 2006
    ....
  2. ncbi Quality of life in pulmonary arterial hypertension: improvement and maintenance with bosentan
    Anne M Keogh
    Victor Chang Research Institute, St Vincent s Hospital, Sydney, Australia
    J Heart Lung Transplant 26:181-7. 2007
    ..The VITAL study assessed the effect of bosentan on quality of life in patients with WHO Functional Class III or IV PAH (idiopathic or associated with connective tissue diseases)...
  3. pmc Hemodynamics in pulmonary arterial hypertension (PAH): do they explain long-term clinical outcomes with PAH-specific therapy?
    Peter Steele
    Department of Epidemiology and Preventative Medicine, Monash University, Melbourne, Vic, Australia
    BMC Cardiovasc Disord 10:9. 2010
    ..There remains a need to differentiate between available therapies and current endpoint responses which in turn, could be used to guide treatment selection and provide long-term prognostic information for patients...
  4. ncbi Sirolimus in de novo heart transplant recipients reduces acute rejection and prevents coronary artery disease at 2 years: a randomized clinical trial
    Anne Keogh
    St Vincent s Hospital, Xavier 4, Victoria St, Darlinghurst, Sydney, New South Wales 2010, Australia
    Circulation 110:2694-700. 2004
    ..Its effects on rejection and transplant vasculopathy in human heart transplant recipients are unknown...
  5. ncbi Long-term benefits of mycophenolate mofetil after heart transplantation
    Anne Keogh
    Heart Transplant Unit, St Vincent s Hospital, Sydney, Australia
    Transplantation 79:S45-6. 2005
    ..Malignancy was numerically but not significantly lower at 3 years; in open label experience up to 7 years, it is diminished by 37% on MMF. MMF protects heart transplant recipients against both vasculopathy and malignancy...
  6. ncbi Improving outcomes in heart transplantation: the potential of proliferation signal inhibitors
    A Keogh
    Heart and Lung Transplant Unit, St Vincent s Hospital, Sydney, Australia
    Transplant Proc 37:1S-3S. 2005
  7. ncbi Calcineurin inhibitors in heart transplantation
    Anne Keogh
    Victor Chang Cardiac Research Institute and Heart Lung Transplant Unit, St Vincent s Hospital, Darlinghurst, New South Wales, Australia
    J Heart Lung Transplant 23:S202-6. 2004
    ..Because cyclosporine and tacrolimus have similar efficacy against acute rejection the choice of CNI for heart transplant recipients should be based on the relative risk of cardiovascular and renal side effects...
  8. ncbi Pulmonary arterial hypertension: a new era in management
    Anne M Keogh
    Xavier 4, St Vincent s Hospital, Victoria Street, Darlinghurst, NSW 2010, Australia
    Med J Aust 178:564-7. 2003
    ..Best management of PAH is comprehensive and multidisciplinary. Centres of excellence are needed in geographically strategic areas. Aggressive efforts must be made to diagnose PAH and to facilitate access to effective therapies...
  9. ncbi Interventional and surgical modalities of treatment in pulmonary hypertension
    Anne M Keogh
    St Vincent s Hospital, Sydney, NSW, Australia
    J Am Coll Cardiol 54:S67-77. 2009
    ..Right ventricular synchronization therapy has not yet been tested. Novel shunts (e.g., Potts anastomosis) also hold promise. All surgery for pulmonary hypertension should be performed in centers with experience in these techniques...
  10. doi The Bosentan Patient Registry: long-term survival in pulmonary arterial hypertension
    A Keogh
    St Vincent s Hospital, Sydney, John Wlodarczyk Consulting Services, Newcastle, New South Wales, Australia
    Intern Med J 41:227-34. 2011
    ..The primary aim of the registry was to collect survival data in patients with pulmonary arterial hypertension (PAH) treated with bosentan...
  11. doi Survival after the initiation of combination therapy in patients with pulmonary arterial hypertension: an Australian collaborative report
    A Keogh
    St Vincent s Hospital, Xavier 4, Victoria St, Darlinghurst, NSW 2010, Australia
    Intern Med J 41:235-44. 2011
    ..In clinical practice, combination therapy is often used in patients deteriorating on monotherapy, despite the absence of firm evidence from randomized controlled controls...
  12. ncbi Efficacy and safety of pravastatin vs simvastatin after cardiac transplantation
    A Keogh
    Heart Transplant Unit and Victor Chang Research Unit, St Vincent s Hospital, Sydney, Australia
    J Heart Lung Transplant 19:529-37. 2000
    ..For safety and pharmacokinetic reasons, pravastatin should be considered the statin of choice after heart transplantation...
  13. ncbi Pulmonary hypertension and breathlessness: is it a combination we can ignore?
    G Strange
    University of Notre Dame, Fremantle, Western Australia Pulmonary Research, Pulmonary Hypertension Society ANZ, Inc, Sydney, New South Wales, Australia Royal Prince Alfred Hospital, Sydney, New South Wales, Australia
    Intern Med J 44:114-23. 2014
    ..We also review the current treatment options on monotherapy and in poly-pharmacy or combination therapy, along with the strategic management implications of the lack of funded combination therapy associated with prognosis. ..
  14. ncbi Predicting the occurrence of diabetes mellitus in recipients of heart transplants
    B Depczynski
    Diabetes Centre, St Vincent s Hospital, Darlinghurst, Sydney, New South Wales, Australia
    Diabet Med 17:15-9. 2000
    ..To establish the incidence of post-transplant diabetes mellitus (PTDM) and factors predictive of its development...
  15. ncbi Protective effect of short-tem calcitriol or cyclical etidronate on bone loss after cardiac or lung transplantation
    K Henderson
    Bone and Mineral Research Program, Garvan Institute of Medical Research, Sydney, Australia
    J Bone Miner Res 16:565-71. 2001
    ..These data suggest short-term prophylaxis with calcitriol or cyclical etidronate is partially effective in reducing bone loss after cardiac or lung transplantation but treatment needs to be continued for a longer term...
  16. ncbi Chronic sildenafil lowers transpulmonary gradient and improves cardiac output allowing successful heart transplantation
    Andrew Jabbour
    Heart Transplant Unit, St Vincent s Hospital, Sydney, New South Wales, Australia
    Eur J Heart Fail 9:674-7. 2007
    ..This study aimed to assess the effects of chronic sildenafil administration on the PVR, transpulmonary gradient (TPG), and cardiac output (CO) in patients with heart failure awaiting heart transplantation...
  17. ncbi Severe diverticulitis after heart, lung, and heart-lung transplantation
    Raffi A Qasabian
    Department of Colorectal Surgery, St Vincent s Hospital, Sydney, Australia
    J Heart Lung Transplant 23:845-9. 2004
    ....
  18. pmc Successful valganciclovir treatment of post-transplant cytomegalovirus infection in the presence of UL97 mutation N597D
    Jenna M Iwasenko
    Virology Division, Department of Microbiology, SEALS, POWH and UNSW Research Laboratories, Prince of Wales Hospital, Randwick, NSW, Australia
    J Med Virol 81:507-10. 2009
    ..Accurate interpretation of genotypic test results ultimately requires experimental determination of the level of resistance conferred by newly discovered UL97 mutations...
  19. ncbi Reversal of chronic cyclosporine nephrotoxicity after heart transplantation-potential role of mycophenolate mofetil
    Takeo Tedoriya
    Heart and Lung Transplant Unit, St Vincent s Hospital, Sydney, Australia
    J Heart Lung Transplant 21:976-82. 2002
    ....
  20. ncbi Safety and efficacy of transition from subcutaneous treprostinil to oral sildenafil in patients with pulmonary arterial hypertension
    Anne M Keogh
    Heart Lung Transplant Unit, St Vincent s Hospital, Sydney, Australia
    J Heart Lung Transplant 26:1079-83. 2007
    ....
  21. ncbi Reduction of immunosuppressant therapy requirement in heart transplantation by calcitriol
    N Kathryn Briffa
    Bone and Mineral Research Program, Garvan Institute of Medical Research, Sydney, NSW, Australia
    Transplantation 75:2133-4. 2003
    ....
  22. ncbi Decision support tool to individualize cyclosporine dose in stable, long-term heart transplant recipients receiving metabolic inhibitors: overcoming limitations of cyclosporine C2 monitoring
    John E Ray
    Department of Clinical Pharmacology and Toxicology, SydPath, St Vincent s Hospital, Sydney, Australia
    J Heart Lung Transplant 25:1223-9. 2006
    ....
  23. ncbi Apparent clearance of sirolimus in heart transplant recipients: impact of primary diagnosis and serum lipids
    Hamim Zahir
    Department of Biomedical and Pharmaceutical Sciences, College of Pharmacy, University of Rhode Island, Kingston, 02881, USA
    Ther Drug Monit 28:614-22. 2006
    ..This information may assist in dose individualization of sirolimus in transplant recipients...
  24. ncbi Similar efficacy and safety of enteric-coated mycophenolate sodium (EC-MPS, myfortic) compared with mycophenolate mofetil (MMF) in de novo heart transplant recipients: results of a 12-month, single-blind, randomized, parallel-group, multicenter study
    Jon A Kobashigawa
    Department of Cardiology, University of California at Los Angeles, Los Angeles, California 90095, USA
    J Heart Lung Transplant 25:935-41. 2006
    ..Enteric-coated mycophenolate sodium (EC-MPS, myfortic) is an advanced formulation that delays the release of mycophenolic acid (MPA). Its efficacy and safety has been proven in several clinical trials in renal transplantation...
  25. ncbi Bosentan for the treatment of pulmonary arterial hypertension associated with congenital cardiac disease
    Eugene Kotlyar
    St Vincent s Hospital, Sydney, Australia
    Cardiol Young 16:268-74. 2006
    ..We sought to evaluate its effect in adults with Eisenmenger's syndrome...
  26. ncbi Prehydration alone is sufficient to prevent contrast-induced nephropathy after day-only angiography procedures--a randomised controlled trial
    Eugene Kotlyar
    Heart and Lung Transplant Unit, Cardiology Department, St Vincent s Hospital, Xavier 4, Victoria St, Darlinghurst, NSW 2010, Australia
    Heart Lung Circ 14:245-51. 2005
    ..It is uncertain whether administration of intravenous (IV) anti-oxidant, N-acetylcysteine (NAC), can prevent reduction in renal function and whether this is a cost-effective approach...
  27. ncbi Cyclosporin C(2) and C(0) concentration monitoring in stable, long-term heart transplant recipients receiving metabolic inhibitors
    John E Ray
    Department of Clinical Pharmacology and Toxicology, Institute of Laboratory Medicine, Sydney, Australia
    J Heart Lung Transplant 22:715-22. 2003
    ....
  28. ncbi Nitric oxide pathway and phosphodiesterase inhibitors in pulmonary arterial hypertension
    Hossein A Ghofrani
    Department of Internal Medicine Pulmonary Hypertension Center, University Hospital, Giessen, Germany
    J Am Coll Cardiol 43:68S-72S. 2004
    ..The results of such studies have to confirm the current encouraging findings before recommendations regarding the use of PDE-5 inhibitors as a new treatment for PH can be made...
  29. ncbi The use of clinical reasoning to promote patient choice
    Anne M Keogh
    Clinical Solutions Ltd, Thurcaston, Leicester, UK
    EDTNA ERCA J 28:151-2. 2002
  30. ncbi Mycoplasma hominis infection in heart and lung transplantation
    Peter M Hopkins
    Heart Lung Transplant Unit, St Vincent s Hospital, Darlinghurst, Sydney, Australia
    J Heart Lung Transplant 21:1225-9. 2002
    ..This cluster raises the question of nosocomial transmission of infection and supports a recommendation for single-room isolation and universal precautions for infected individuals...
  31. ncbi Ambrisentan therapy for pulmonary arterial hypertension
    Nazzareno Galie
    University of Bologna, Bologna, Italy
    J Am Coll Cardiol 46:529-35. 2005
    ..The purpose of this study was to examine the efficacy and safety of four doses of ambrisentan, an oral endothelin type A receptor-selective antagonist, in patients with pulmonary arterial hypertension (PAH)...