Research Topics
Genomes and GenesSpecies | B C NordinSummaryAffiliation: South Australia Country: Australia Publications
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Publications
The difference between hazard and risk in the relation between bone density and fractureB E Christopher Nordin
Institute of Medical and Veterinary Science, Frome Road, PO Box 14, Rundle Mall, Adelaide, 5000, South Australia, Australia
Calcif Tissue Int 80:349-52. 2007..Here, we show how "hazard" can be converted to risk and how misleading the current practice of equating relative hazards with relative risks can be...
Nutrition, osteoporosis, and agingB E Nordin
Division of Clinical Biochemistry, Institute of Medical and Veterinary Science, Adelaide, South Australia, Australia
Ann N Y Acad Sci 854:336-51. 1998..Vitamin D supplementation has been shown to retard bone loss and reduce hip fracture incidence in elderly women...
Calcium malabsorption does not cause secondary hyperparathyroidismB E Christopher Nordin
Clinical Biochemistry, SA Pathology, Frome Road, Adelaide, SA 5000, Australia
Calcif Tissue Int 85:31-6. 2009....
The effect of calcium supplementation on bone loss in 32 controlled trials in postmenopausal womenB E C Nordin
Endocrine and Metabolic Unit, Royal Adelaide Hospital, Adelaide, Australia
Osteoporos Int 20:2135-43. 2009..07% p.a. and in the treated subjects -0.27% p.a. (P for difference <0.001). The effect was similar at all measured sites and at all doses of 700 mg or more but became weaker after 4 years...
In defence of calciumB E Christopher Nordin
Endocrine and Metabolic Unit, Royal Adelaide Hospital, Adelaide, SA, Australia
Med J Aust 194:3-4. 2011..Reports of adverse events related to calcium supplementation should be supported by rigorous evidence...
Effect of age on calcium absorption in postmenopausal womenB E Christopher Nordin
Division of Clinical Biochemistry, Institute of Medical and Veterinary Science, Adelaide, Australia
Am J Clin Nutr 80:998-1002. 2004..It is assumed that calcium absorption decreases with age, but this is not well documented. We report a study that addresses this issue...
Should the treatment of osteoporosis be more selective?B E Christopher Nordin
Division of Clinical Biochemistry, Institute of Medical and Veterinary Science, Frome Road, 5000, Adelaide, Australia
Osteoporos Int 14:99-102. 2003
Radiocalcium absorption is reduced in postmenopausal women with vertebral and most types of peripheral fracturesB E Christopher Nordin
Division of Clinical Biochemistry, Institute of Medical and Veterinary Science, Frome Road, 5000 Adelaide, South Australia, Australia
Osteoporos Int 15:27-31. 2004..We conclude that impaired calcium absorption is particularly associated with those fractures for which osteoporosis is a significant risk factor...
A longitudinal study of bone-related biochemical changes at the menopauseB E Christopher Nordin
Division of Clinical Biochemistry, Institute of Medical and Veterinary Science, Department of Medicine, University of Adelaide, Adelaide, Australia
Clin Endocrinol (Oxf) 61:123-30. 2004..To evaluate the effects of the menopause on bone-related biochemical variables in a longitudinal study...
Vitamin D status: effects on parathyroid hormone and 1, 25-dihydroxyvitamin D in postmenopausal womenA G Need
Division of Clinical Biochemistry, Institute of Medical and Veterinary Science, and the Department of Medicine, Royal Adelaide Hospital, Adelaide, Australia
Am J Clin Nutr 71:1577-81. 2000..The relation between the rise in parathyroid hormone (PTH) with age and the decrease in 25(OH)D is not clear. Neither is there any consensus on the serum concentration of 25(OH)D required for bone health...
Vitamin D metabolites and calcium absorption in severe vitamin D deficiencyAllan G Need
Division of Clinical Biochemistry, Institute of Medical and Veterinary Science, University of Adelaide, Adelaide, South Australia
J Bone Miner Res 23:1859-63. 2008..Further studies are needed to see how these changes correlate with the histological changes of osteomalacia...
Suppression of C-terminal telopeptide in hypovitaminosis D requires calcium as well as vitamin DS Devika C Thomas
Chemical Pathology, SA Pathology, Frome Road, Adelaide 5000, Adelaide, SA, Australia
Calcif Tissue Int 86:367-74. 2010..We suggest that calcium may elevate serum 25OHD by prolonging its half-life and that it may have an inhibitory effect on bone resorption independent of, or in addition to, its suppression of PTH...
Relationship between fasting serum glucose, age, body mass index and serum 25 hydroxyvitamin D in postmenopausal womenAllan G Need
Division of Clinical Biochemistry, Institute of Medical and Veterinary Science, University of Adelaide, Adelaide, SA, Australia
Clin Endocrinol (Oxf) 62:738-41. 2005....
Recalculation of the calcium requirement of adult menB E Christopher Nordin
Endocrine and Metabolic Unit, Royal Adelaide Hospital, Adelaide, South Australia, Australia
Am J Clin Nutr 93:442-5. 2011..There is uncertainty about the calcium requirement with particular respect to age and sex differences and the calculation of skin calcium losses...
The effects of age and other variables on serum parathyroid hormone in postmenopausal women attending an osteoporosis centerAllan G Need
Division of Clinical Biochemistry, Royal Adelaide Hospital, Adelaide, South Australia 5000
J Clin Endocrinol Metab 89:1646-9. 2004..After adjustment for serum ionized calcium, body weight, and age, the rise in serum PTH appeared to start when serum 25(OH)D fell less than 80 nmol/liter...
Misconceptions - vitamin D insufficiency causes malabsorption of calciumAllan G Need
The Division of Clinical Biochemistry, Institute of Medical and Veterinary Science, The Department of Medicine, University of Adelaide and The Hanson Institute, Adelaide, South Australia 5000, Australia
Bone 42:1021-4. 2008..Using two previously published series of elderly patients we refute this common assumption and present evidence that low circulating levels of 25 hydroxyvitamin D have a direct and deleterious effect on bone...
Suppression of parathyroid hormone and bone resorption by calcium carbonate and calcium citrate in postmenopausal womenSunethra D C Thomas
Division of Clinical Biochemistry, Institute of Medical and Veterinary Science, SA Health, Adelaide, South Australia, Australia
Calcif Tissue Int 83:81-4. 2008..This may be because calcium as citrate is better absorbed than calcium as carbonate. If calcium citrate can be used in lower doses, it may be better tolerated than calcium carbonate...
The importance of calculating absolute rather than relative fracture riskGraeme Tucker
Health Statistics Unit, Department of Health, Government of South Australia, Adelaide, South Australia
Bone 41:937-41. 2007..We conclude that multiplicative factors can be applied to odds but not to risk and that multipliers of risk tend to overstate the effect of continuous variables, such as age and T-score, particularly towards the end of their ranges...
The effect of menopause on bone mineral density and bone-related biochemical variables in Indonesian womenMaryantoro Oemardi
Department of Medicine, Cipto Mangunkusumo Hospital, Jakarta, Indonesia
Clin Endocrinol (Oxf) 67:93-100. 2007..To determine the effects of menopause on bone-related variables in Indonesian women and to compare them with corresponding data in Caucasian Australian women...
Treatment of osteoporosis: why, whom, when and how to treatB E Christopher Nordin
Med J Aust 181:287; author reply 287-8. 2004
Bone density and fracture riskB E Christopher Nordin
Med J Aust 189:7-8. 2008
Calcium supplementation does not increase mortalityBenjamin M P Tang
Med J Aust 188:547. 2008
