A G Need

Summary

Affiliation: South Australia
Country: Australia

Publications

  1. ncbi The effects of age and other variables on serum parathyroid hormone in postmenopausal women attending an osteoporosis center
    Allan G Need
    Division of Clinical Biochemistry, Royal Adelaide Hospital, Adelaide, South Australia 5000
    J Clin Endocrinol Metab 89:1646-9. 2004
  2. ncbi Relationship between fasting serum glucose, age, body mass index and serum 25 hydroxyvitamin D in postmenopausal women
    Allan G Need
    Division of Clinical Biochemistry, Institute of Medical and Veterinary Science, University of Adelaide, Adelaide, SA, Australia
    Clin Endocrinol (Oxf) 62:738-41. 2005
  3. ncbi Bone resorption markers in vitamin D insufficiency
    Allan G Need
    Department of Clinical Biochemistry, Institute of Medical and Veterinary Science, Frome Road, Adelaide, South Australia 5000, Australia
    Clin Chim Acta 368:48-52. 2006
  4. ncbi Seasonal change in osteoid thickness and mineralization lag time in ambulant patients
    Allan G Need
    Institute of Medical and Veterinary Science, Adelaide, South Australia, Australia
    J Bone Miner Res 22:757-61. 2007
  5. ncbi Vitamin D status: effects on parathyroid hormone and 1, 25-dihydroxyvitamin D in postmenopausal women
    A G Need
    Division of Clinical Biochemistry, Institute of Medical and Veterinary Science, and the Department of Medicine, Royal Adelaide Hospital, Adelaide, Australia
    Am J Clin Nutr 71:1577-81. 2000
  6. doi Misconceptions - vitamin D insufficiency causes malabsorption of calcium
    Allan G Need
    The Division of Clinical Biochemistry, Institute of Medical and Veterinary Science, The Department of Medicine, University of Adelaide and The Hanson Institute, Adelaide, South Australia 5000, Australia
    Bone 42:1021-4. 2008
  7. ncbi Relation between calcium absorption and serum calcitriol in normal men: evidence for age-related intestinal resistance to calcitriol
    F Scopacasa
    Division of Clinical Biochemistry, Institute of Medical and Veterinary Science, Adelaide, South Australia, Australia
    Eur J Clin Nutr 58:264-9. 2004
  8. ncbi The effect of chlorothiazide on bone-related biochemical variables in normal post-menopausal women
    C A Peh
    Department of Medicine, Royal Adelaide Hospital, Australia
    J Am Geriatr Soc 41:513-6. 1993
  9. ncbi Relationship between serum 25-hydroxyvitamin D and bone resorption markers in vitamin D insufficiency
    D Jesudason
    Clinical Biochemistry, Institute of Medical and Veterinary Science, Adelaide, SA, Australia
    Bone 31:626-30. 2002
  10. ncbi Biochemical effects of a calcium supplement in postmenopausal women with primary hyperparathyroidism
    M Horowitz
    Department of Medicine, Royal Adelaide Hospital, Australia
    Horm Metab Res 26:39-42. 1994

Collaborators

Detail Information

Publications28

  1. ncbi The effects of age and other variables on serum parathyroid hormone in postmenopausal women attending an osteoporosis center
    Allan G Need
    Division of Clinical Biochemistry, Royal Adelaide Hospital, Adelaide, South Australia 5000
    J Clin Endocrinol Metab 89:1646-9. 2004
    ..After adjustment for serum ionized calcium, body weight, and age, the rise in serum PTH appeared to start when serum 25(OH)D fell less than 80 nmol/liter...
  2. ncbi Relationship between fasting serum glucose, age, body mass index and serum 25 hydroxyvitamin D in postmenopausal women
    Allan G Need
    Division of Clinical Biochemistry, Institute of Medical and Veterinary Science, University of Adelaide, Adelaide, SA, Australia
    Clin Endocrinol (Oxf) 62:738-41. 2005
    ....
  3. ncbi Bone resorption markers in vitamin D insufficiency
    Allan G Need
    Department of Clinical Biochemistry, Institute of Medical and Veterinary Science, Frome Road, Adelaide, South Australia 5000, Australia
    Clin Chim Acta 368:48-52. 2006
    ..In addition, it appears that optimal levels of bone resorption markers in this population are at or just below the mean level for premenopausal women...
  4. ncbi Seasonal change in osteoid thickness and mineralization lag time in ambulant patients
    Allan G Need
    Institute of Medical and Veterinary Science, Adelaide, South Australia, Australia
    J Bone Miner Res 22:757-61. 2007
    ..Seasonal changes in mineralization correlated inversely with serum 25-hydroxyvitamin D but not the more active metabolite, 1,25-dihydroxyvitamin D. This implies that the latter is produced in bone...
  5. ncbi Vitamin D status: effects on parathyroid hormone and 1, 25-dihydroxyvitamin D in postmenopausal women
    A G Need
    Division of Clinical Biochemistry, Institute of Medical and Veterinary Science, and the Department of Medicine, Royal Adelaide Hospital, Adelaide, Australia
    Am J Clin Nutr 71:1577-81. 2000
    ..The relation between the rise in parathyroid hormone (PTH) with age and the decrease in 25(OH)D is not clear. Neither is there any consensus on the serum concentration of 25(OH)D required for bone health...
  6. doi Misconceptions - vitamin D insufficiency causes malabsorption of calcium
    Allan G Need
    The Division of Clinical Biochemistry, Institute of Medical and Veterinary Science, The Department of Medicine, University of Adelaide and The Hanson Institute, Adelaide, South Australia 5000, Australia
    Bone 42:1021-4. 2008
    ..Using two previously published series of elderly patients we refute this common assumption and present evidence that low circulating levels of 25 hydroxyvitamin D have a direct and deleterious effect on bone...
  7. ncbi Relation between calcium absorption and serum calcitriol in normal men: evidence for age-related intestinal resistance to calcitriol
    F Scopacasa
    Division of Clinical Biochemistry, Institute of Medical and Veterinary Science, Adelaide, South Australia, Australia
    Eur J Clin Nutr 58:264-9. 2004
    ..To obtain information on the causes of age-related bone loss in men and the concomitant decline in calcium absorption...
  8. ncbi The effect of chlorothiazide on bone-related biochemical variables in normal post-menopausal women
    C A Peh
    Department of Medicine, Royal Adelaide Hospital, Australia
    J Am Geriatr Soc 41:513-6. 1993
    ..To evaluate the effects of short-term administration of chlorothiazide on fasting urinary hydroxyproline, an index of bone resorption, and other bone-related biochemical parameters in normal post-menopausal women...
  9. ncbi Relationship between serum 25-hydroxyvitamin D and bone resorption markers in vitamin D insufficiency
    D Jesudason
    Clinical Biochemistry, Institute of Medical and Veterinary Science, Adelaide, SA, Australia
    Bone 31:626-30. 2002
    ..We conclude that rises in three bone resorption markers and ALP can be detected in postmenopausal women when the serum 25(OH)D level falls below 60 nmol/L. Levels above this may be required for optimal bone health...
  10. ncbi Biochemical effects of a calcium supplement in postmenopausal women with primary hyperparathyroidism
    M Horowitz
    Department of Medicine, Royal Adelaide Hospital, Australia
    Horm Metab Res 26:39-42. 1994
    ..01) and the urinary hydroxyproline/creatinine (p < 0.02) fell. These results indicate that calcium loading inhibits bone resorption in postmenopausal women with mild primary hyperparathyroidism...
  11. ncbi Bone density and bone-related biochemical variables in normal men: a longitudinal study
    F Scopacasa
    Department of Medicine, University of Adelaide, South Australia, Australia
    J Gerontol A Biol Sci Med Sci 57:M385-91. 2002
    ..This was a longitudinal study over a median interval of 41 months. The study was conducted in Adelaide, Australia. Study participants were 123 healthy male subjects, between the ages of 20 and 83 years...
  12. ncbi Relationships between intestinal calcium absorption, serum vitamin D metabolites and smoking in postmenopausal women
    A G Need
    Division of Clinical Biochemistry, Institute of Medical and Veterinary Science, Adelaide, SA, Australia
    Osteoporos Int 13:83-8. 2002
    ..This impairment of calcium absorption could lead to accelerated bone loss and limit the usefulness of dietary calcium supplementation...
  13. ncbi Relations between calcium intake, calcitriol, polymorphisms of the vitamin D receptor gene, and calcium absorption in premenopausal women
    J M Wishart
    Department of Medicine, Royal Adelaide Hospital, Australia
    Am J Clin Nutr 65:798-802. 1997
    ..We conclude that serum calcitriol and dietary calcium are independent determinants of calcium absorption in premenopausal women and that VDR gene polymorphisms influence calcium absorption...
  14. ncbi Nutrition, osteoporosis, and aging
    B E Nordin
    Division of Clinical Biochemistry, Institute of Medical and Veterinary Science, Adelaide, South Australia, Australia
    Ann N Y Acad Sci 854:336-51. 1998
    ..Vitamin D supplementation has been shown to retard bone loss and reduce hip fracture incidence in elderly women...
  15. ncbi Cross sectional and longitudinal study of bone mineral content of the distal forearm in adult premenopausal women
    J M Wishart
    Department of Medicine, University of Adelaide, Australia
    Horm Metab Res 23:185-7. 1991
    ..3% yr in those over 35 years of age (P less than 0.10). This data suggests that if there is any distal forearm bone loss before the menopause it is negligible...
  16. ncbi Effects of dose and timing of calcium supplementation on bone resorption in early menopausal women
    Franca Scopacasa
    Division of Clinical Biochemistry, Institute of Medical and Veterinary Science, Royal Adelaide Hospital, Adelaide 5000, South Australia, Australia
    Horm Metab Res 34:44-7. 2002
    ..We conclude that the acute administration of 500 mg of calcium in the morning and 1000 mg in the evening to early postmenopausal women suppresses bone resorption markers during both the day and night...
  17. ncbi A longitudinal study of bone-related biochemical changes at the menopause
    B E Christopher Nordin
    Division of Clinical Biochemistry, Institute of Medical and Veterinary Science, Department of Medicine, University of Adelaide, Adelaide, Australia
    Clin Endocrinol (Oxf) 61:123-30. 2004
    ..To evaluate the effects of the menopause on bone-related biochemical variables in a longitudinal study...
  18. doi Vitamin D, glucose, insulin, and insulin sensitivity
    Kamilia Tai
    University of Adelaide Department of Medicine, Royal Adelaide Hospital, Adelaide, Australia
    Nutrition 24:279-85. 2008
    ..Clinical trials are needed to determine whether vitamin D treatment of vitamin D-deficient individuals is able to prevent or treat diabetes mellitus...
  19. ncbi The effect of menopause on bone mineral density and bone-related biochemical variables in Indonesian women
    Maryantoro Oemardi
    Department of Medicine, Cipto Mangunkusumo Hospital, Jakarta, Indonesia
    Clin Endocrinol (Oxf) 67:93-100. 2007
    ..To determine the effects of menopause on bone-related variables in Indonesian women and to compare them with corresponding data in Caucasian Australian women...
  20. ncbi Additive effects of raloxifene and alendronate on bone density and biochemical markers of bone remodeling in postmenopausal women with osteoporosis
    Olof Johnell
    Department of Orthopaedics, Universiteitssjukhuset MAS, Malmø, Sweden
    J Clin Endocrinol Metab 87:985-92. 2002
    ..RLX+ALN reduced bone turnover more than either drug alone, resulting in greater BMD increment, but whether this difference reflects better fracture risk reduction was not assessed in this study...
  21. ncbi A system for improving vitamin D nutrition in residential care
    Alison E R Wigg
    Royal Adelaide Hospital, Adelaide, SA, Australia
    Med J Aust 185:195-8. 2006
    ..To assess the feasibility of administering an inexpensive preparation of vitamin D(3) 100 000 IU orally 3 monthly to aged-care residents...
  22. ncbi Efficacy and safety of raloxifene 60 milligrams/day in postmenopausal Asian women
    Annie W C Kung
    Department of Medicine, The University of Hong Kong, Division of Endocrinology, Queen Mary Hospital, Hong Kong, People s Republic of China
    J Clin Endocrinol Metab 88:3130-6. 2003
    ..No case of venous thromboembolism was reported. The effects of raloxifene 60 mg/d on bone turnover, BMD, and serum lipids in healthy postmenopausal Asian women were similar to that previously reported in Caucasian women...
  23. ncbi Radiocalcium absorption is reduced in postmenopausal women with vertebral and most types of peripheral fractures
    B E Christopher Nordin
    Division of Clinical Biochemistry, Institute of Medical and Veterinary Science, Frome Road, 5000 Adelaide, South Australia, Australia
    Osteoporos Int 15:27-31. 2004
    ..We conclude that impaired calcium absorption is particularly associated with those fractures for which osteoporosis is a significant risk factor...
  24. ncbi Does the response of bone mass to calcium supplements depend on calcium absorption efficiency?
    Emma Smith
    Division of Clinical Biochemistry, Institute of Medical and Veterinary Science, Department of Medicine, University of Adelaide, SA 5000, Australia
    Eur J Endocrinol 151:759-63. 2004
    ....
  25. ncbi Effect of age on calcium absorption in postmenopausal women
    B E Christopher Nordin
    Division of Clinical Biochemistry, Institute of Medical and Veterinary Science, Adelaide, Australia
    Am J Clin Nutr 80:998-1002. 2004
    ..It is assumed that calcium absorption decreases with age, but this is not well documented. We report a study that addresses this issue...
  26. ncbi Treatment of osteoporosis: why, whom, when and how to treat
    B E Christopher Nordin
    Med J Aust 181:287; author reply 287-8. 2004
  27. doi Suppression of parathyroid hormone and bone resorption by calcium carbonate and calcium citrate in postmenopausal women
    Sunethra D C Thomas
    Division of Clinical Biochemistry, Institute of Medical and Veterinary Science, SA Health, Adelaide, South Australia, Australia
    Calcif Tissue Int 83:81-4. 2008
    ..This may be because calcium as citrate is better absorbed than calcium as carbonate. If calcium citrate can be used in lower doses, it may be better tolerated than calcium carbonate...
  28. ncbi The importance of calculating absolute rather than relative fracture risk
    Graeme Tucker
    Health Statistics Unit, Department of Health, Government of South Australia, Adelaide, South Australia
    Bone 41:937-41. 2007
    ..We conclude that multiplicative factors can be applied to odds but not to risk and that multipliers of risk tend to overstate the effect of continuous variables, such as age and T-score, particularly towards the end of their ranges...