Research Topics
| Maria MakridesSummaryAffiliation: South Australia Country: Australia Publications
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Publications
DHA supplementation during the perinatal period and neurodevelopment: do some babies benefit more than others?Maria Makrides
Women s and Children s Health Research Institute, North Adelaide, SA 5006, Australia
Prostaglandins Leukot Essent Fatty Acids 88:87-90. 2013....- Is there a dietary requirement for DHA in pregnancy?Maria Makrides
Women s and Children s Health Research Institute, Level 7, Clarence Rieger Building, Women s and Children s Hospital, 72 King William Road, North Adelaide, SA 5006, Australia
Prostaglandins Leukot Essent Fatty Acids 81:171-4. 2009..On the other hand, large-scale trials assessing marine oil supplementation with large doses indicate that DHA supplementation in pregnancy is safe... - Effect of DHA supplementation during pregnancy on maternal depression and neurodevelopment of young children: a randomized controlled trialMaria Makrides
Child Nutrition Research Centre, Women s and Children s Health Research Institute, Women s and Children s Hospital, 72 King William Rd, North Adelaide SA 5006, Australia
JAMA 304:1675-83. 2010..Uncertainty about the benefits of dietary docosahexaenoic acid (DHA) for pregnant women and their children exists, despite international recommendations that pregnant women increase their DHA intakes... - Impact of fatty acid status on growth and neurobehavioural development in humansMaria Makrides
Child Nutrition Research Centre, Women s and Children s Health Research Institute, Flinders Medical Centre, 72 King William Road, Bedford Park, SA 5006, Australia
Matern Child Nutr 7:80-8. 2011..Further work is required to determine whether dietary n-3 LCPUFA is neuroprotective for children from disadvantaged or low-income backgrounds... - Maternal supplementation with docosahexaenoic acid during pregnancy does not affect early visual development in the infant: a randomized controlled trialLisa G Smithers
Women s and Children s Health Research Institute, Children, Youth and Women s Health Service, North Adelaide, Australia
Am J Clin Nutr 93:1293-9. 2011..The docosahexaenoic acid (DHA) intake of pregnant women is lower than estimates of the DHA accretion by the fetus, and recommendations were made to increase the DHA intake of pregnant women... 
Higher dose of docosahexaenoic acid in the neonatal period improves visual acuity of preterm infants: results of a randomized controlled trialLisa G Smithers
Women s and Children s Health Research Institute and the School of Agriculture, Food and Wine, University of Adelaide, Adelaide, SA, Australia
Am J Clin Nutr 88:1049-56. 2008..Preterm infants have improved visual outcomes when fed a formula containing 0.2-0.4% docosahexaenoic acid (DHA) compared with infants fed no DHA, but the optimal DHA dose is unknown...- Effect of increasing protein content of human milk fortifier on growth in preterm infants born at <31 wk gestation: a randomized controlled trialJacqueline Miller
Child Nutrition Research Centre, Women s and Children s Health Research Institute, Flinders Medical Centre, Bedford Park, Australia
Am J Clin Nutr 95:648-55. 2012..Preterm human milk-fed infants often experience suboptimal growth despite the use of human milk fortifier (HMF). The extra protein supplied in fortifiers may be inadequate to meet dietary protein requirements for preterm infants... - Pre- and post-term growth in pre-term infants supplemented with higher-dose DHA: a randomised controlled trialCarmel T Collins
Women s and Children s Health Research Institute, Child Nutrition Research Centre, Flinders Medical Centre, Flinders Drive, Bedford Park, SA 5042, Australia
Br J Nutr 105:1635-43. 2011..Our data show that DHA up to 1 % total dietary fatty acids does not adversely affect growth... - Fish-oil supplementation in pregnancy does not reduce the risk of gestational diabetes or preeclampsiaShao J Zhou
Women s and Children s Health Research Centre, North Adelaide, Australia
Am J Clin Nutr 95:1378-84. 2012..There is uncertainty regarding the efficacy of increasing n-3 long-chain PUFA (LCPUFA) intake during pregnancy in reducing the risk of gestational diabetes mellitus (GDM) and preeclampsia... - Neurodevelopmental outcomes of preterm infants fed high-dose docosahexaenoic acid: a randomized controlled trialMaria Makrides
Child Nutrition Research Centre, Women s and Children s Health Research Institute, Women s and Children s Hospital, 72 King William Rd, North Adelaide SA 5006, Australia
JAMA 301:175-82. 2009..Uncertainty exists about the benefit of dietary docosahexaenoic acid (DHA) on the neurodevelopment of preterm infants... - Effect of long-chain polyunsaturated fatty acid supplementation of preterm infants on disease risk and neurodevelopment: a systematic review of randomized controlled trialsLisa G Smithers
Child Health Research Institute, Child, Youth and Women s Health Service, North Adelaide, Australia
Am J Clin Nutr 87:912-20. 2008..Supplementation of preterm formulas with long-chain polyunsaturated fatty acids (LCPUFAs) is based on their effectiveness to increase blood status and improve visual outcomes. Dispute remains over their efficacy on global development... - Effect of iron supplementation during pregnancy on the intelligence quotient and behavior of children at 4 y of age: long-term follow-up of a randomized controlled trialShao J Zhou
Child Nutrition Research Centre and the Department of Pediatrics, Women's and Children's Hospital, University of Adelaide, North Adelaide, Australia
Am J Clin Nutr 83:1112-7. 2006..CONCLUSIONS: Prenatal iron supplementation that reduces the incidence of iron deficiency anemia from 11% to 1% has no effect on the IQ of the offspring at 4 y of age... - Effect of iron supplementation during pregnancy on the behaviour of children at early school age: long-term follow-up of a randomised controlled trialAnnie G Parsons
Child Nutrition Research Centre, Flinders Medical Centre and Women s and Children s Hospital, Child Health Research Institute, North Adelaide, SA, Australia
Br J Nutr 99:1133-9. 2008..026). We conclude that prenatal Fe supplementation had no consistent effect on child behaviour at early school age in this study population. Further investigation regarding the long-term effects of this common practice is warranted... - Conversion of linoleic acid and alpha-linolenic acid to long-chain polyunsaturated fatty acids (LCPUFAs), with a focus on pregnancy, lactation and the first 2 years of lifeRobert A Gibson
Child Nutrition Research Centre, Women s and Children s Health Research Institute, Children, Youth and Women s Health Service, North Adelaide, South Australia, Australia
Matern Child Nutr 7:17-26. 2011.... - The effect of alpha-linolenic acid and linoleic acid on the growth and development of formula-fed infants: a systematic review and meta-analysis of randomized controlled trialsTuesday Udell
Department of Paediatrics and Child Health, Flinders University, Bedford Park, South Australia, Australia
Lipids 40:1-11. 2005..The findings suggest that ALA-supplemented diets improve the DHA status of infants. Further studies are needed to provide convincing evidence regarding the effects of ALA supplementation of formula on infant growth and development... - Dietary nucleotides do not alter erythrocyte long-chain polyunsaturated fatty acids in formula-fed term infantsRobert A Gibson
Child Health Research Institute, Flinders Medical Centre and Flinders University, Bedford Park, South Australia 5042, Australia
Lipids 40:631-4. 2005..We conclude that there is no induction of LCPUFA accumulation in erythrocyte phospholipids of term, formula-fed infants following 7 mon of NT supplementation... - The role of fats in the lifecycle stages: pregnancy and the first year of lifeMaria Makrides
Child Nutrition Research Centre, Child Health Research Institute, Women's and Children's Hospital, Flinders Medical Centre, Adelaide, SA 5042, Australia
Med J Aust 176:S111-2. 2002..Debate continues about the importance of DHA supplementation for term infants; the current consensus is that the benefits of DHA supplementation in term infants are smaller than for preterm infants... - Higher protein and energy intake is associated with increased weight gain in pre-term infantsCarmel T Collins
Child Nutrition Research Centre, Women s and Children s Hospital, Flinders Medical Centre and Women s and Children s Health Research Institute, Adelaide, Australia
J Paediatr Child Health 46:96-102. 2010..To characterise and compare the nutritional management and growth in infants <33 weeks' gestation in two tertiary centres... - Outcomes for mothers and their babies: do n-3 long-chain polyunsaturated fatty acids and seafoods make a difference?Maria Makrides
Women s and Children s Health Research Institute, North Adelaide, SA, Australia
J Am Diet Assoc 108:1622-6. 2008 - Safety of supplementing infant formula with long-chain polyunsaturated fatty acids and Bifidobacterium lactis in term infants: a randomised controlled trialRobert A Gibson
Women s and Children s Health Research Institute, Children, Youth and Women s Health Service, North Adelaide, Australia
Br J Nutr 101:1706-13. 2009..No influence of the supplements on the response to vaccines was observed. Growth characteristics of term infants fed the starter formula containing a probiotic and LC-PUFA were similar to standard formula-fed infants... - Home environment, not duration of breast-feeding, predicts intelligence quotient of children at four yearsShao J Zhou
Child Nutrition Research Centre, Flinders Medical Centre and Women s and Children s Hospital, Child Health Research Institute, North Adelaide, South Australia, Australia
Nutrition 23:236-41. 2007..We investigated the relation between duration of breast-feeding in infancy and the intelligence quotient (IQ) of children at 4 y of age in a well-nourished population of an industrialized country... - Carbohydrate intake is the main determinant of growth in infants born <33 weeks' gestation when protein intake is adequateCarmel T Collins
Child Health Research Institute, Women s and Children s Hospital, North Adelaide and Flinders Medical Centre, Bedford Park, South Australia, Australia
Nutrition 24:451-7. 2008..We investigated the relative contribution of macronutrients to postnatal growth in preterm infants born <33 wk of gestation... - Nutrient intakes and status of preschool children in Adelaide, South AustraliaShao J Zhou
Women s and Children s Health Research Institute, Adelaide, SA
Med J Aust 196:696-700. 2012..To determine the nutrient intakes and status of preschool children from a representative population sample in Adelaide... - Responses to immunisation with Hib conjugate vaccine in Australian breastfed and formula-fed infantsJoanna S Hawkes
Child Health Research Institute, Flinders Medical Centre and Flinders University, Bedford Park, South Australia, Australia
J Paediatr Child Health 43:597-600. 2007..These observations prompted us to investigate the effect of feeding method on the antibody concentration to Hib polyribosylribitol (PRP) both prior to and 3 months after the primary course of immunisation with Hib (PRP-OMP)... - Routine iron supplementation in pregnancy has no effect on iron status of children at six months and four years of ageShao J Zhou
Child Nutrition Research Centre, Flinders Medical Centre and Women s and Children s Hospital, Child Health Research Institute, North Adelaide, Australia
J Pediatr 151:438-40. 2007..The iron status at 6 months and 4 years of children born to women who were randomly allocated to receive 20 mg of iron daily in the second half of pregnancy did not differ from children of mothers in the control group... - Respiratory hospitalisation of infants supplemented with docosahexaenoic acid as preterm neonatesKerryn Atwell
Neonatal Medicine, Women s and Children s Hospital, North Adelaide, South Australia, Australia
J Paediatr Child Health 49:E17-22. 2013..To determine the effect of neonatal docosahexaenoic acid (DHA) supplementation in preterm infants on later respiratory-related hospitalisations... - Effect of long-chain polyunsaturated fatty acid supplementation during pregnancy or lactation on infant and child body composition: a systematic reviewBeverly S Muhlhausler
School of Agriculture, Food, and Wine, The University of Adelaide, Adelaide, Australia
Am J Clin Nutr 92:857-63. 2010.... - Optimizing DHA levels in piglets by lowering the linoleic acid to alpha-linolenic acid ratioCordula Blank
Department of Paediatrics and Child Health, Flinders Medical Centre, Bedford Park, South Australia 5042, Australia
J Lipid Res 43:1537-43. 2002.... - Nutritional effect of including egg yolk in the weaning diet of breast-fed and formula-fed infants: a randomized controlled trialMaria Makrides
Child Nutrition Research Centre, Child Health Research Institute, Women's and Children's Hospital, North Adelaide, Australia
Am J Clin Nutr 75:1084-92. 2002..Egg yolks may also be a useful source of iron during the weaning period and can be safely included in the weaning diet with no perturbations in plasma cholesterol... - Essential role of fats throughout the lifecycle: summary and recommendationsRobert A Gibson
Child Nutrition Research Centre, Child Health Research Institute, Women's and Children's Hospital, Flinders Medical Centre, Adelaide, SA 5042, Australia
Med J Aust 176:S107-9. 2002 - Efficacy and tolerability of low-dose iron supplements during pregnancy: a randomized controlled trialMaria Makrides
Child Nutrition Research Centre, Child Health Research Institute, and Department of Paediatrics, University of Adelaide, Women s and Children s Hospital, North Adelaide, SA, Australia
Am J Clin Nutr 78:145-53. 2003..Iron deficiency anemia (IDA) is common in pregnant women, but previous trials aimed at preventing IDA used high-dose iron supplements that are known to cause gastrointestinal side effects... - Evaluation of an iron specific checklist for the assessment of dietary iron intake in pregnant and postpartum womenShao J Zhou
Child Nutrition Research Centre, Child Health Research Institute and Department of Paediatrics, University of Adelaide, Women's and Children's Hospital, North Adelaide, South Australia, Australia
Nutrition 21:908-13. 2005..CONCLUSION: This simple iron checklist is a useful tool in describing iron intake of population samples of pregnant women but has limited ability to predict iron status... - Evaluation of dietetic product innovations: the relative role of preclinical and clinical studiesMaria Makrides
Women s and Children s Health Research Institute and University of Adelaide, Adelaide, S A, Australia
Nestle Nutr Workshop Ser Pediatr Program 66:143-50. 2010..Ultimately, there is a need for tests of pragmatic interventions that can easily be incorporated into usual dietary practices of the culture in which it is tested... - Supplementation of infant formula with long-chain polyunsaturated fatty acids does not influence the growth of term infantsMaria Makrides
Applied Nutrition Group, Child Health Research Institute, Women s and Children s Hospital, North Adelaide, SA, Australia
Am J Clin Nutr 81:1094-101. 2005..Adequate growth is an important indicator of health and well-being in infants... - The effect of dairy foods on CHD: a systematic review of prospective cohort studiesRobert A Gibson
Child Youth and Women s Health Service, Women s and Children s Health Research Institute, Level 7, Clarence Reiger Building, North Adelaide, SA, Australia
Br J Nutr 102:1267-75. 2009..This could be due to the limited sensitivity of the dietary assessment methods to detect an effect of a single food in a mixed diet on complex clinical outcomes... - A randomized trial of supplementation with docosahexaenoic acid-rich tuna oil and its effects on the human milk cytokines interleukin 1 beta, interleukin 6, and tumor necrosis factor alphaJoanna S Hawkes
Child Nutrition Research Centre, Flinders Medical Centre, Bedford Park, SA, Australia
Am J Clin Nutr 75:754-60. 2002..CONCLUSIONS: Consumption of < or = 600 mg DHA and 140 mg EPA/d for 4 wk increased n-3 PUFA concentrations in relevant tissues but did not cause perturbations in cytokine concentrations in human milk... - Diet of lactating women and allergic reactions in their infantsDebra Jane Palmer
Child Health Research Institute, and Department of Paediatrics, The University of Adelaide, Women's and Children's Hospital, North Adelaide, South Australia, Australia
Curr Opin Clin Nutr Metab Care 9:284-8. 2006..Controlled trials are required to evaluate the efficacy of maternal dietary n-3 fatty acid interventions in preventing allergic disease in at-risk infants... - The effect of maternal omega-3 (n-3) LCPUFA supplementation during pregnancy on early childhood cognitive and visual development: a systematic review and meta-analysis of randomized controlled trialsJacqueline F Gould
Women s and Children s Health Research Institute, Adelaide, Australia
Am J Clin Nutr 97:531-44. 2013....