M Makrides

Summary

Affiliation: South Australia
Country: Australia

Publications

  1. ncbi request reprint Outcomes for mothers and their babies: do n-3 long-chain polyunsaturated fatty acids and seafoods make a difference?
    Maria Makrides
    Women s and Children s Health Research Institute, North Adelaide, SA, Australia
    J Am Diet Assoc 108:1622-6. 2008
  2. doi request reprint Neurodevelopmental outcomes of preterm infants fed high-dose docosahexaenoic acid: a randomized controlled trial
    Maria Makrides
    Child Nutrition Research Centre, Women s and Children s Health Research Institute, Women s and Children s Hospital, 72 King William Rd, North Adelaide SA 5006, Australia
    JAMA 301:175-82. 2009
  3. ncbi request reprint Marine oil, and other prostaglandin precursor, supplementation for pregnancy uncomplicated by pre-eclampsia or intrauterine growth restriction
    M Makrides
    Child Health Research Institute, Women s and Children s Hospital, 72 King William Road, North Adelaide, SA, Australia 5006
    Cochrane Database Syst Rev 3:CD003402. 2006
  4. ncbi request reprint Randomized controlled trial of fish oil supplementation in pregnancy on childhood allergies
    D J Palmer
    Women s and Children s Health Research Institute, North Adelaide, SA, Australia School of Paediatrics and Child Health, University of Western Australia, Subiaco, WA, Australia
    Allergy 68:1370-6. 2013
  5. pmc Effect of n-3 long chain polyunsaturated fatty acid supplementation in pregnancy on infants' allergies in first year of life: randomised controlled trial
    D J Palmer
    Women s and Children s Health Research Institute, North Adelaide, South Australia, Australia
    BMJ 344:e184. 2012
  6. doi request reprint Effect of maternal egg consumption on breast milk ovalbumin concentration
    D J Palmer
    Department of Paediatrics, Women s and Children s Health Research Institute, The University of Adelaide, Woman s and Children s Hospital, North Adelaide, SA, Australia
    Clin Exp Allergy 38:1186-91. 2008
  7. ncbi request reprint Transforming growth factor beta in human milk does not change in response to modest intakes of docosahexaenoic acid
    J S Hawkes
    Child Nutrition Research Centre, Flinders Medical Centre, Bedford Park, South Australia, Australia
    Lipids 36:1179-81. 2001
  8. ncbi request reprint Effect of two doses of docosahexaenoic acid (DHA) in the diet of preterm infants on infant fatty acid status: results from the DINO trial
    L G Smithers
    Women s and Children s Health Research Institute, Children Youth and Women s Health Service, North Adelaide and Flinders Medical Centre, Flinders Drive, Bedford Park, Australia, Australia
    Prostaglandins Leukot Essent Fatty Acids 79:141-6. 2008
  9. ncbi request reprint n-3 polyunsaturated fatty acid requirements of term infants
    R A Gibson
    Child Nutrition Research Centre, Child Health Research Institute, North Adelaide, Australia
    Am J Clin Nutr 71:251S-5S. 2000
  10. ncbi request reprint Randomized trials with polyunsaturated fatty acid interventions in preterm and term infants: functional and clinical outcomes
    R A Gibson
    Child Health Research Institute at Flinders Centre and Women s and Children s Hospital, Adelaide, SA, Australia
    Lipids 36:873-83. 2001

Detail Information

Publications43

  1. ncbi request reprint Outcomes for mothers and their babies: do n-3 long-chain polyunsaturated fatty acids and seafoods make a difference?
    Maria Makrides
    Women s and Children s Health Research Institute, North Adelaide, SA, Australia
    J Am Diet Assoc 108:1622-6. 2008
  2. doi request reprint Neurodevelopmental outcomes of preterm infants fed high-dose docosahexaenoic acid: a randomized controlled trial
    Maria Makrides
    Child Nutrition Research Centre, Women s and Children s Health Research Institute, Women s and Children s Hospital, 72 King William Rd, North Adelaide SA 5006, Australia
    JAMA 301:175-82. 2009
    ..Uncertainty exists about the benefit of dietary docosahexaenoic acid (DHA) on the neurodevelopment of preterm infants...
  3. ncbi request reprint Marine oil, and other prostaglandin precursor, supplementation for pregnancy uncomplicated by pre-eclampsia or intrauterine growth restriction
    M Makrides
    Child Health Research Institute, Women s and Children s Hospital, 72 King William Road, North Adelaide, SA, Australia 5006
    Cochrane Database Syst Rev 3:CD003402. 2006
    ..It is suggested that the fatty acids of marine foods may be the underlying cause of these associations...
  4. ncbi request reprint Randomized controlled trial of fish oil supplementation in pregnancy on childhood allergies
    D J Palmer
    Women s and Children s Health Research Institute, North Adelaide, SA, Australia School of Paediatrics and Child Health, University of Western Australia, Subiaco, WA, Australia
    Allergy 68:1370-6. 2013
    ..The aim of this study was to determine whether n-3 LCPUFA supplementation of pregnant women reduces IgE-mediated allergic disease in their children...
  5. pmc Effect of n-3 long chain polyunsaturated fatty acid supplementation in pregnancy on infants' allergies in first year of life: randomised controlled trial
    D J Palmer
    Women s and Children s Health Research Institute, North Adelaide, South Australia, Australia
    BMJ 344:e184. 2012
    ..To determine whether dietary n-3 long chain polyunsaturated fatty acid (LCPUFA) supplementation of pregnant women with a fetus at high risk of allergic disease reduces immunoglobulin E associated eczema or food allergy at 1 year of age...
  6. doi request reprint Effect of maternal egg consumption on breast milk ovalbumin concentration
    D J Palmer
    Department of Paediatrics, Women s and Children s Health Research Institute, The University of Adelaide, Woman s and Children s Hospital, North Adelaide, SA, Australia
    Clin Exp Allergy 38:1186-91. 2008
    ..Maternal dietary avoidance of egg has been recommended to treat egg allergy in breastfed infants. However, only one of three randomized controlled trials have produced evidence in favour of this recommendation...
  7. ncbi request reprint Transforming growth factor beta in human milk does not change in response to modest intakes of docosahexaenoic acid
    J S Hawkes
    Child Nutrition Research Centre, Flinders Medical Centre, Bedford Park, South Australia, Australia
    Lipids 36:1179-81. 2001
    ..The DHA increase in milk and plasma was proportional to dietary DHA. There was no relationship between milk DHA status and TGFbeta1 and TGFbeta2 levels...
  8. ncbi request reprint Effect of two doses of docosahexaenoic acid (DHA) in the diet of preterm infants on infant fatty acid status: results from the DINO trial
    L G Smithers
    Women s and Children s Health Research Institute, Children Youth and Women s Health Service, North Adelaide and Flinders Medical Centre, Flinders Drive, Bedford Park, Australia, Australia
    Prostaglandins Leukot Essent Fatty Acids 79:141-6. 2008
    ..2, p<0.0005). Feeding preterm infants human milk and formula with 1% DHA raises but does not saturate erythrocyte phospholipids with DHA. Milk exceeding 1% DHA may be required to increase DHA status to levels seen in term infants...
  9. ncbi request reprint n-3 polyunsaturated fatty acid requirements of term infants
    R A Gibson
    Child Nutrition Research Centre, Child Health Research Institute, North Adelaide, Australia
    Am J Clin Nutr 71:251S-5S. 2000
    ..Therefore, there is a clear need to associate a measure of LCPUFA status with a specific functional outcome before any recommendations can be made for achieving optimal or maximal LCPUFA status...
  10. ncbi request reprint Randomized trials with polyunsaturated fatty acid interventions in preterm and term infants: functional and clinical outcomes
    R A Gibson
    Child Health Research Institute at Flinders Centre and Women s and Children s Hospital, Adelaide, SA, Australia
    Lipids 36:873-83. 2001
    ..In summary, there appear to be few safety concerns relating to the use of LC-PUFA in infant nutrition. The potential medium- and long-term effects of including these compounds in the early diet of infants remain to be assessed...
  11. ncbi request reprint Higher dose of docosahexaenoic acid in the neonatal period improves visual acuity of preterm infants: results of a randomized controlled trial
    Lisa G Smithers
    Women s and Children s Health Research Institute and the School of Agriculture, Food and Wine, University of Adelaide, Adelaide, SA, Australia
    Am J Clin Nutr 88:1049-56. 2008
    ..Preterm infants have improved visual outcomes when fed a formula containing 0.2-0.4% docosahexaenoic acid (DHA) compared with infants fed no DHA, but the optimal DHA dose is unknown...
  12. ncbi request reprint Effect of long-chain polyunsaturated fatty acid supplementation of preterm infants on disease risk and neurodevelopment: a systematic review of randomized controlled trials
    Lisa G Smithers
    Child Health Research Institute, Child, Youth and Women s Health Service, North Adelaide, Australia
    Am J Clin Nutr 87:912-20. 2008
    ..Supplementation of preterm formulas with long-chain polyunsaturated fatty acids (LCPUFAs) is based on their effectiveness to increase blood status and improve visual outcomes. Dispute remains over their efficacy on global development...
  13. ncbi request reprint Long-chain polyunsaturated fatty acid requirements during pregnancy and lactation
    M Makrides
    Department of Obstetrics and Gynaecology, University of Adelaide, Women s and Children s Hospital, 72 King William Road, North Adelaide, SA 5006, Australia
    Am J Clin Nutr 71:307S-11S. 2000
    ..Careful attention should be paid to study design, measurement of appropriate health outcomes, and defining minimum and maximum plasma n-3 LCPUFA concentrations that are optimal for both mothers and infants...
  14. ncbi request reprint Effect of iron supplementation during pregnancy on the behaviour of children at early school age: long-term follow-up of a randomised controlled trial
    Annie G Parsons
    Child Nutrition Research Centre, Flinders Medical Centre and Women s and Children s Hospital, Child Health Research Institute, North Adelaide, SA, Australia
    Br J Nutr 99:1133-9. 2008
    ..026). We conclude that prenatal Fe supplementation had no consistent effect on child behaviour at early school age in this study population. Further investigation regarding the long-term effects of this common practice is warranted...
  15. ncbi request reprint Effect of iron supplementation during pregnancy on the intelligence quotient and behavior of children at 4 y of age: long-term follow-up of a randomized controlled trial
    Shao J Zhou
    Child Nutrition Research Centre and the Department of Pediatrics, Women s and Children s Hospital, University of Adelaide, North Adelaide, Australia
    Am J Clin Nutr 83:1112-7. 2006
    ..Iron supplements are often prescribed during pregnancy despite the lack of intervention trials that have assessed the effects of supplementation in pregnancy on childhood development...
  16. doi request reprint Dietary alpha-linolenic acid enhances omega-3 long chain polyunsaturated fatty acid levels in chicken tissues
    L R Kartikasari
    Foodplus Research Centre, School of Agriculture, Food and Wine, University of Adelaide, Adelaide, SA, Australia
    Prostaglandins Leukot Essent Fatty Acids 87:103-9. 2012
    ..In contrast, arachidonic acid (AA) was reduced in response to increasing dietary ALA...
  17. ncbi request reprint Long-chain polyunsaturated fatty acids in breast milk: are they essential?
    R A Gibson
    Child Nutrition Research Centre, Child Health Research Institute, Flinders Medical Centre, Adelaide, SA, Australia
    Adv Exp Med Biol 501:375-83. 2001
    ..However, only tissue DHA levels have consistently correlated with outcomes...
  18. ncbi request reprint Efficacy and tolerability of low-dose iron supplements during pregnancy: a randomized controlled trial
    Maria Makrides
    Child Nutrition Research Centre, Child Health Research Institute, and Department of Paediatrics, University of Adelaide, Women s and Children s Hospital, North Adelaide, SA, Australia
    Am J Clin Nutr 78:145-53. 2003
    ..Iron deficiency anemia (IDA) is common in pregnant women, but previous trials aimed at preventing IDA used high-dose iron supplements that are known to cause gastrointestinal side effects...
  19. doi request reprint Effect of DHA supplementation during pregnancy on maternal depression and neurodevelopment of young children: a randomized controlled trial
    Maria Makrides
    Child Nutrition Research Centre, Women s and Children s Health Research Institute, Women s and Children s Hospital, 72 King William Rd, North Adelaide SA 5006, Australia
    JAMA 304:1675-83. 2010
    ..Uncertainty about the benefits of dietary docosahexaenoic acid (DHA) for pregnant women and their children exists, despite international recommendations that pregnant women increase their DHA intakes...
  20. ncbi request reprint Supplementation of infant formula with long-chain polyunsaturated fatty acids does not influence the growth of term infants
    Maria Makrides
    Applied Nutrition Group, Child Health Research Institute, Women s and Children s Hospital, North Adelaide, SA, Australia
    Am J Clin Nutr 81:1094-101. 2005
    ..Adequate growth is an important indicator of health and well-being in infants...
  21. doi request reprint Is there a dietary requirement for DHA in pregnancy?
    Maria Makrides
    Women s and Children s Health Research Institute, Level 7, Clarence Rieger Building, Women s and Children s Hospital, 72 King William Road, North Adelaide, SA 5006, Australia
    Prostaglandins Leukot Essent Fatty Acids 81:171-4. 2009
    ..On the other hand, large-scale trials assessing marine oil supplementation with large doses indicate that DHA supplementation in pregnancy is safe...
  22. doi request reprint Impact of fatty acid status on growth and neurobehavioural development in humans
    Maria Makrides
    Child Nutrition Research Centre, Women s and Children s Health Research Institute, Flinders Medical Centre, 72 King William Road, Bedford Park, SA 5006, Australia
    Matern Child Nutr 7:80-8. 2011
    ..Further work is required to determine whether dietary n-3 LCPUFA is neuroprotective for children from disadvantaged or low-income backgrounds...
  23. ncbi request reprint Should we lower the dose of iron when treating anaemia in pregnancy? A randomized dose-response trial
    S J Zhou
    Child Nutrition Research Centre, Flinders Medical Centre and Women s and Children s Hospital, Child Health Research Institute, North Adelaide, SA, Australia
    Eur J Clin Nutr 63:183-90. 2009
    ..To compare the efficacy and side effects of low-dose vs high-dose iron supplements to correct anaemia in pregnancy...
  24. ncbi request reprint Perinatal characteristics may influence the outcome of visual acuity
    M Makrides
    Child Nutrition Research Centre, Child Health Research Institute and Women's and Children's Hospital, North Adelaide, SA 5006, Australia
    Lipids 36:897-900. 2001
    ..It is possible that a combination of perinatal factors could accumulate to either mask or enhance effects of diet on VEP acuity, given the relatively modest effects of long-chain PUFA on visual outcome...
  25. doi request reprint Safety of supplementing infant formula with long-chain polyunsaturated fatty acids and Bifidobacterium lactis in term infants: a randomised controlled trial
    Robert A Gibson
    Women s and Children s Health Research Institute, Children, Youth and Women s Health Service, North Adelaide, Australia
    Br J Nutr 101:1706-13. 2009
    ..No influence of the supplements on the response to vaccines was observed. Growth characteristics of term infants fed the starter formula containing a probiotic and LC-PUFA were similar to standard formula-fed infants...
  26. ncbi request reprint Evaluation of an iron specific checklist for the assessment of dietary iron intake in pregnant and postpartum women
    Shao J Zhou
    Child Nutrition Research Centre, Child Health Research Institute and Department of Paediatrics, University of Adelaide, Women s and Children s Hospital, North Adelaide, South Australia, Australia
    Nutrition 21:908-13. 2005
    ..This study developed and validated an iron checklist for assessing dietary iron intake of pregnant and postpartum women...
  27. ncbi request reprint Nutritional effect of including egg yolk in the weaning diet of breast-fed and formula-fed infants: a randomized controlled trial
    Maria Makrides
    Child Nutrition Research Centre, Child Health Research Institute, Women s and Children s Hospital, North Adelaide, Australia
    Am J Clin Nutr 75:1084-92. 2002
    ..Egg yolks can be a source of docosahexaenoic acid (DHA) and iron but are often associated with adverse consequences on plasma cholesterol...
  28. doi request reprint Prediction of body water compartments in preterm infants by bioelectrical impedance spectroscopy
    C T Collins
    Foodplus Research Centre, Women s and Children s Health Research Institute, Women s and Children s Hospital and Flinders Medical Centre, Adelaide, South Australia, Australia
    Eur J Clin Nutr 67:S47-53. 2013
    ..Bioelectrical impedance may provide such a method. The aim of this study was to develop resistivity coefficients appropriate for use in bioelectrical impedance spectroscopy (BIS) analysis of body water volumes in preterm infants...
  29. ncbi request reprint Polyunsaturated fatty acids and infant visual development: a critical appraisal of randomized clinical trials
    R A Gibson
    Child Nutrition Research Centre, Flinders Medical Centre, Bedford Park Adelaide, SA, Australia
    Lipids 34:179-84. 1999
    ..Our evaluation of the trials to date suggests that the definitive answer to the degree to which dietary long-chain PUFA is likely to influence visual development may only be resolved with impeccably conducted RCT...
  30. ncbi request reprint A randomized trial of supplementation with docosahexaenoic acid-rich tuna oil and its effects on the human milk cytokines interleukin 1 beta, interleukin 6, and tumor necrosis factor alpha
    Joanna S Hawkes
    Child Nutrition Research Centre, Flinders Medical Centre, Bedford Park, SA, Australia
    Am J Clin Nutr 75:754-60. 2002
    ..The production of proinflammatory cytokines by human peripheral blood mononuclear cells (PBMCs) can be modified by dietary n-3 PUFAs...
  31. ncbi request reprint Essential role of fats throughout the lifecycle: summary and recommendations
    Robert A Gibson
    Child Nutrition Research Centre, Child Health Research Institute, Women s and Children s Hospital, Flinders Medical Centre, Adelaide, SA 5042, Australia
    Med J Aust 176:S107-9. 2002
  32. ncbi request reprint The role of fats in the lifecycle stages: pregnancy and the first year of life
    Maria Makrides
    Child Nutrition Research Centre, Child Health Research Institute, Women s and Children s Hospital, Flinders Medical Centre, Adelaide, SA 5042, Australia
    Med J Aust 176:S111-2. 2002
    ..Debate continues about the importance of DHA supplementation for term infants; the current consensus is that the benefits of DHA supplementation in term infants are smaller than for preterm infants...
  33. ncbi request reprint Routine iron supplementation in pregnancy has no effect on iron status of children at six months and four years of age
    Shao J Zhou
    Child Nutrition Research Centre, Flinders Medical Centre and Women s and Children s Hospital, Child Health Research Institute, North Adelaide, Australia
    J Pediatr 151:438-40. 2007
    ..The iron status at 6 months and 4 years of children born to women who were randomly allocated to receive 20 mg of iron daily in the second half of pregnancy did not differ from children of mothers in the control group...
  34. ncbi request reprint Effect of cooked and raw egg consumption on ovalbumin content of human milk: a randomized, double-blind, cross-over trial
    D J Palmer
    Child Health Research Institute, Women s and Children s Hospital, North Adelaide, SA, Australia
    Clin Exp Allergy 35:173-8. 2005
    ..Maternal avoidance of egg intake has been recommended to treat egg allergy in breastfed infants...
  35. ncbi request reprint Effect of dietary nucleotide supplementation on growth and immune function in term infants: a randomized controlled trial
    J S Hawkes
    Child Health Research Institute, Flinders Medical Centre and Flinders University, Bedford Park, SA, Australia
    Eur J Clin Nutr 60:254-64. 2006
    ..To examine the effect of nucleotide (NT)-supplemented cow's milk-based formula on growth and biochemical indices of immune function in healthy infants...
  36. doi request reprint Carbohydrate intake is the main determinant of growth in infants born <33 weeks' gestation when protein intake is adequate
    Carmel T Collins
    Child Health Research Institute, Women s and Children s Hospital, North Adelaide and Flinders Medical Centre, Bedford Park, South Australia, Australia
    Nutrition 24:451-7. 2008
    ..We investigated the relative contribution of macronutrients to postnatal growth in preterm infants born <33 wk of gestation...
  37. ncbi request reprint Dietary nucleotides do not alter erythrocyte long-chain polyunsaturated fatty acids in formula-fed term infants
    Robert A Gibson
    Child Health Research Institute, Flinders Medical Centre and Flinders University, Bedford Park, South Australia 5042, Australia
    Lipids 40:631-4. 2005
    ..We conclude that there is no induction of LCPUFA accumulation in erythrocyte phospholipids of term, formula-fed infants following 7 mon of NT supplementation...
  38. doi request reprint Higher protein and energy intake is associated with increased weight gain in pre-term infants
    Carmel T Collins
    Child Nutrition Research Centre, Women s and Children s Hospital, Flinders Medical Centre and Women s and Children s Health Research Institute, Adelaide, Australia
    J Paediatr Child Health 46:96-102. 2010
    ..To characterise and compare the nutritional management and growth in infants <33 weeks' gestation in two tertiary centres...
  39. ncbi request reprint Diet of lactating women and allergic reactions in their infants
    Debra Jane Palmer
    Child Health Research Institute, and Department of Paediatrics, The University of Adelaide, Women s and Children s Hospital, North Adelaide, South Australia, Australia
    Curr Opin Clin Nutr Metab Care 9:284-8. 2006
    ..To evaluate whether the diet of lactating women modulates the development of allergic disease in their children...
  40. ncbi request reprint The effect of alpha-linolenic acid and linoleic acid on the growth and development of formula-fed infants: a systematic review and meta-analysis of randomized controlled trials
    Tuesday Udell
    Department of Paediatrics and Child Health, Flinders University, Bedford Park, South Australia, Australia
    Lipids 40:1-11. 2005
    ..The findings suggest that ALA-supplemented diets improve the DHA status of infants. Further studies are needed to provide convincing evidence regarding the effects of ALA supplementation of formula on infant growth and development...
  41. ncbi request reprint Selenium status of term infants fed selenium-supplemented formula in a randomized dose-response trial
    Lynne Daniels
    Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Australia
    Am J Clin Nutr 88:70-6. 2008
    ..The optimal form and dose of selenium supplementation required to achieve indicators of selenium status equivalent to those in breastfed infants are unclear...
  42. ncbi request reprint The importance of early complementary feeding in the development of oral tolerance: concerns and controversies
    Susan L Prescott
    School of Paediatrics and Child Health Research, University of Western Australia, Perth, WA, Australia
    Pediatr Allergy Immunol 19:375-80. 2008
    ..It will also examine the growing case for introducing complementary foods from around 4 months of age and maintaining breastfeeding during this early feeding period, for at least 6 months if possible...
  43. ncbi request reprint Plasma phospholipid fatty acid composition as a biomarker of habitual dietary fat intake in an ethnically diverse cohort
    Allison M Hodge
    Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Australia
    Nutr Metab Cardiovasc Dis 17:415-26. 2007
    ....