Research Topics
Genomes and Genes | Sonja KlebeSummaryAffiliation: South Australia Country: Australia Publications
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Detail Information
Publications
Malignant mesothelioma with heterologous elements: clinicopathological correlation of 27 cases and literature reviewSonja Klebe
Department of Anatomical Pathology, Flinders University of South Australia, Adelaide, SA, Australia
Mod Pathol 21:1084-94. 2008....
A practical approach to interpretation of corneal specimensSonja Klebe
Department of Anatomical Pathology, Flinders Medical Centre, Bedford Park, SA, Australia
Adv Anat Pathol 11:150-61. 2004..It is the role of the pathologist to make optimal use of a small specimen to reach the relevant diagnosis in the minimum space of time...
Delayed surface opacification of a hydroview intraocular lensSonja Klebe
Department of Anatomical Pathology, Flinders Medical Centre and Flinders University, Adelaide, South Australia, Australia
Clin Exp Optom 89:386-9. 2006..Pathological analysis of an explanted IOL may assist in a better understanding of the condition and may become relevant in medico-legal proceedings...
Sarcomatoid mesothelioma: a clinical-pathologic correlation of 326 casesSonja Klebe
Department of Anatomical Pathology, Flinders University and Medical Centre, Adelaide, Australia
Mod Pathol 23:470-9. 2010..The relationship with asbestos exposure--particularly amosite--and an association with pleural plaques and less often asbestosis is confirmed...
Association of TCF4 and CLU polymorphisms with Fuchs' endothelial dystrophy and implication of CLU and TGFBI proteins in the disease processAbraham Kuot
Department of Ophthalmology, Flinders University, Bedford Park, South Australia, Australia
Eur J Hum Genet 20:632-8. 2012..Differential expression of CLU and TGFBI proteins in FED-affected corneas provides novel insights into the disease mechanism...
Gene therapy for corneal dystrophies and disease, where are we?Keryn A Williams
Department of Ophthalmology, Flinders University, Adelaide, SA 5042, Australia
Curr Opin Ophthalmol 23:276-9. 2012..We assess the studies on vector systems for delivery of transgenes to the cornea that have been published over the last year and summarize new work on the identification of specific transgenes for corneal diseases...
Rejection and acceptance of corneal allograftsSonja Klebe
Department of Ophthalmology, Flinders University, Adelaide, Australia
Curr Opin Organ Transplant 14:4-9. 2009..Corneal transplantation is successful in the short-term, but the long-term prognosis has not improved over the past 20 years. Here, we review recent findings that may contribute to improved corneal allograft survival...
Early stages of mesothelioma, screening and biomarkersSonja Klebe
Department of Anatomical Pathology, Flinders University of South Australia, Adelaide, SA, Australia
Recent Results Cancer Res 189:169-93. 2011....
Diagnosis of epithelial mesothelioma using tree-based regression analysis and a minimal panel of antibodiesSonja Klebe
Department of Anatomical Pathology, Flinders Medical Centre, Adelaide, SA, Australia
Pathology 41:140-8. 2009..It was the aim of this study to use a novel statistical approach to identify a minimal panel of antibodies, which would make this distinction in the majority of cases...
Acute critical leg ischemia: an uncommon initial manifestation of esophageal adenocarcinomaTuck Y Yong
Department of General Medicine, Flinders Medical Centre, Bedford Park, Adelaide, South Australia, Australia
J Palliat Med 12:841-4. 2009..Where possible in such setting, revascularisation can be attempted to provide pain relief and improve quality of life but major vascular reconstructive surgery is not recommended in most cases...
Pythium insidiosum keratitis in an Australian childPaul R Badenoch
Department of Ophthalmology, Flinders Medical Centre and Flinders University, Bedford Park, South Australia, Australia
Clin Experiment Ophthalmol 37:806-9. 2009..Although the diagnosis of P. insidiosum keratitis is not difficult, and the organism is susceptible in vitro to a number of antimicrobial agents, early corneal transplantation remains the treatment of choice...
Malignant pleural mesothelioma with associated minimal change disease and acute renal failureJordan Y Z Li
Department of Renal Medicine, Flinders Medical Centre and Flinders University, Adelaide, South Australia, Australia
Ren Fail 32:1012-5. 2010..The renal biopsy demonstrated MCD. The underlying pathogenesis of this association remains unknown...
Novel quantitative trait loci for central corneal thickness identified by candidate gene analysis of osteogenesis imperfecta genesDavid P Dimasi
Department of Ophthalmology, Flinders University, Adelaide, SA 5042, Australia
Hum Genet 127:33-44. 2010....
Exposure to cyclic oxygen sufficient for development of oxygen-induced retinopathy does not induce bronchopulmonary dysplasia in ratsSonja Klebe
Department of Anatomical Pathology, Flinders University and Flinders Medical Centre, South Australia, Australia
Exp Lung Res 36:175-82. 2010....
Evaluation of mesoporous silicon/polycaprolactone composites as ophthalmic implantsSoheila Kashanian
School of Chemical and Physical Sciences, Flinders University, GPO Box 2100, Adelaide, SA 5001, Australia
Acta Biomater 6:3566-72. 2010..We suggest that these novel composite materials hold considerable promise as scaffolds in tissue engineering with controlled release applications...
Identification of LOXL1 protein and Apolipoprotein E as components of surgically isolated pseudoexfoliation material by direct mass spectrometryShiwani Sharma
Department of Ophthalmology, Flinders University, Bedford Park, South Australia 5042, Australia
Exp Eye Res 89:479-85. 2009..In conclusion, additional as yet unknown components are present in pathological PEX deposits and mass spectrometry of "isolated" PEX material is an effective strategy for their identification...
Prolongation of sheep corneal allograft survival by transfer of the gene encoding ovine IL-12-p40 but not IL-4 to donor corneal endotheliumSonja Klebe
Department of Ophthalmology, Flinders University and Flinders Medical Centre, Adelaide, South Australia, Australia
J Immunol 175:2219-26. 2005..These findings have important implications for the development of novel strategies to improve human corneal graft survival...
Reduced surface tension normalizes static lung mechanics in a rodent chronic heart failure modelDani Louise Dixon
Intensive and Critical Care Unit, Flinders Medical Centre, Bedford Park, Adelaide, South Australia 5042, Australia
Am J Respir Crit Care Med 180:181-7. 2009..Chronic elevation of pulmonary microvascular pressure in chronic heart failure results in compensatory changes in the lung that reduce alveolar fluid filtration and protect against pulmonary microvascular rupture...
Resolution of primary acquired melanosis with atypia after minimal mitomycin C treatmentJern Yee Chen
Clin Experiment Ophthalmol 35:865-7. 2007..This case report describes successful treatment of PAM with atypia with a single four day cycle of 0.02% MMC...
