Sonja Klebe

Summary

Affiliation: South Australia
Country: Australia

Publications

  1. doi request reprint Malignant mesothelioma with heterologous elements: clinicopathological correlation of 27 cases and literature review
    Sonja Klebe
    Department of Anatomical Pathology, Flinders University of South Australia, Adelaide, SA, Australia
    Mod Pathol 21:1084-94. 2008
  2. ncbi request reprint A practical approach to interpretation of corneal specimens
    Sonja Klebe
    Department of Anatomical Pathology, Flinders Medical Centre, Bedford Park, SA, Australia
    Adv Anat Pathol 11:150-61. 2004
  3. ncbi request reprint Delayed surface opacification of a hydroview intraocular lens
    Sonja Klebe
    Department of Anatomical Pathology, Flinders Medical Centre and Flinders University, Adelaide, South Australia, Australia
    Clin Exp Optom 89:386-9. 2006
  4. doi request reprint Challenges and controversies in the diagnosis of malignant mesothelioma: Part 2. Malignant mesothelioma subtypes, pleural synovial sarcoma, molecular and prognostic aspects of mesothelioma, BAP1, aquaporin-1 and microRNA
    Douglas W Henderson
    Department of Surgical Pathology, SA Pathology, Flinders Medical Centre, Adelaide, South Australia
    J Clin Pathol 66:854-61. 2013
  5. doi request reprint Sarcomatoid mesothelioma: a clinical-pathologic correlation of 326 cases
    Sonja Klebe
    Department of Anatomical Pathology, Flinders University and Medical Centre, Adelaide, Australia
    Mod Pathol 23:470-9. 2010
  6. pmc Association of TCF4 and CLU polymorphisms with Fuchs' endothelial dystrophy and implication of CLU and TGFBI proteins in the disease process
    Abraham Kuot
    Department of Ophthalmology, Flinders University, Bedford Park, South Australia, Australia
    Eur J Hum Genet 20:632-8. 2012
  7. doi request reprint Challenges and controversies in the diagnosis of mesothelioma: Part 1. Cytology-only diagnosis, biopsies, immunohistochemistry, discrimination between mesothelioma and reactive mesothelial hyperplasia, and biomarkers
    Douglas W Henderson
    Department of Surgical Pathology, SA Pathology, Flinders Medical Centre, Bedford Park, South Australia
    J Clin Pathol 66:847-53. 2013
  8. doi request reprint Gene therapy for corneal dystrophies and disease, where are we?
    Keryn A Williams
    Department of Ophthalmology, Flinders University, Adelaide, SA 5042, Australia
    Curr Opin Ophthalmol 23:276-9. 2012
  9. doi request reprint Diagnosis of epithelial mesothelioma using tree-based regression analysis and a minimal panel of antibodies
    Sonja Klebe
    Department of Anatomical Pathology, Flinders Medical Centre, Adelaide, SA, Australia
    Pathology 41:140-8. 2009
  10. doi request reprint Early stages of mesothelioma, screening and biomarkers
    Sonja Klebe
    Department of Anatomical Pathology, Flinders University of South Australia, Adelaide, SA, Australia
    Recent Results Cancer Res 189:169-93. 2011

Collaborators

Detail Information

Publications25

  1. doi request reprint Malignant mesothelioma with heterologous elements: clinicopathological correlation of 27 cases and literature review
    Sonja Klebe
    Department of Anatomical Pathology, Flinders University of South Australia, Adelaide, SA, Australia
    Mod Pathol 21:1084-94. 2008
    ....
  2. ncbi request reprint A practical approach to interpretation of corneal specimens
    Sonja Klebe
    Department of Anatomical Pathology, Flinders Medical Centre, Bedford Park, SA, Australia
    Adv Anat Pathol 11:150-61. 2004
    ..It is the role of the pathologist to make optimal use of a small specimen to reach the relevant diagnosis in the minimum space of time...
  3. ncbi request reprint Delayed surface opacification of a hydroview intraocular lens
    Sonja Klebe
    Department of Anatomical Pathology, Flinders Medical Centre and Flinders University, Adelaide, South Australia, Australia
    Clin Exp Optom 89:386-9. 2006
    ..Pathological analysis of an explanted IOL may assist in a better understanding of the condition and may become relevant in medico-legal proceedings...
  4. doi request reprint Challenges and controversies in the diagnosis of malignant mesothelioma: Part 2. Malignant mesothelioma subtypes, pleural synovial sarcoma, molecular and prognostic aspects of mesothelioma, BAP1, aquaporin-1 and microRNA
    Douglas W Henderson
    Department of Surgical Pathology, SA Pathology, Flinders Medical Centre, Adelaide, South Australia
    J Clin Pathol 66:854-61. 2013
    ....
  5. doi request reprint Sarcomatoid mesothelioma: a clinical-pathologic correlation of 326 cases
    Sonja Klebe
    Department of Anatomical Pathology, Flinders University and Medical Centre, Adelaide, Australia
    Mod Pathol 23:470-9. 2010
    ..The relationship with asbestos exposure--particularly amosite--and an association with pleural plaques and less often asbestosis is confirmed...
  6. pmc Association of TCF4 and CLU polymorphisms with Fuchs' endothelial dystrophy and implication of CLU and TGFBI proteins in the disease process
    Abraham Kuot
    Department of Ophthalmology, Flinders University, Bedford Park, South Australia, Australia
    Eur J Hum Genet 20:632-8. 2012
    ..Differential expression of CLU and TGFBI proteins in FED-affected corneas provides novel insights into the disease mechanism...
  7. doi request reprint Challenges and controversies in the diagnosis of mesothelioma: Part 1. Cytology-only diagnosis, biopsies, immunohistochemistry, discrimination between mesothelioma and reactive mesothelial hyperplasia, and biomarkers
    Douglas W Henderson
    Department of Surgical Pathology, SA Pathology, Flinders Medical Centre, Bedford Park, South Australia
    J Clin Pathol 66:847-53. 2013
    ....
  8. doi request reprint Gene therapy for corneal dystrophies and disease, where are we?
    Keryn A Williams
    Department of Ophthalmology, Flinders University, Adelaide, SA 5042, Australia
    Curr Opin Ophthalmol 23:276-9. 2012
    ..We assess the studies on vector systems for delivery of transgenes to the cornea that have been published over the last year and summarize new work on the identification of specific transgenes for corneal diseases...
  9. doi request reprint Diagnosis of epithelial mesothelioma using tree-based regression analysis and a minimal panel of antibodies
    Sonja Klebe
    Department of Anatomical Pathology, Flinders Medical Centre, Adelaide, SA, Australia
    Pathology 41:140-8. 2009
    ..It was the aim of this study to use a novel statistical approach to identify a minimal panel of antibodies, which would make this distinction in the majority of cases...
  10. doi request reprint Early stages of mesothelioma, screening and biomarkers
    Sonja Klebe
    Department of Anatomical Pathology, Flinders University of South Australia, Adelaide, SA, Australia
    Recent Results Cancer Res 189:169-93. 2011
    ....
  11. doi request reprint Rejection and acceptance of corneal allografts
    Sonja Klebe
    Department of Ophthalmology, Flinders University, Adelaide, Australia
    Curr Opin Organ Transplant 14:4-9. 2009
    ..Corneal transplantation is successful in the short-term, but the long-term prognosis has not improved over the past 20 years. Here, we review recent findings that may contribute to improved corneal allograft survival...
  12. doi request reprint Acute critical leg ischemia: an uncommon initial manifestation of esophageal adenocarcinoma
    Tuck Y Yong
    Department of General Medicine, Flinders Medical Centre, Bedford Park, Adelaide, South Australia, Australia
    J Palliat Med 12:841-4. 2009
    ..Where possible in such setting, revascularisation can be attempted to provide pain relief and improve quality of life but major vascular reconstructive surgery is not recommended in most cases...
  13. doi request reprint Comparative outcomes of penetrating and component endothelial cell corneal allografts in outbred sheep
    Richard A D Mills
    Department of Ophthalmology, Flinders University, Adelaide, South Australia, Australia
    Cell Transplant 23:133-8. 2014
    ..We conclude that, in the absence of immunosuppression, all endothelial cell allografts do undergo immunological rejection, albeit at a slower rate than penetrating grafts. ..
  14. ncbi request reprint Novel therapeutic approaches for corneal disease
    Keryn A Williams
    Department of Ophthalmology, Flinders University, Adelaide, Australia
    Discov Med 15:291-9. 2013
    ..Finally, gene therapy is being tested in experimental animals to improve the outcomes of corneal transplantation, and to halt or reverse the pathophysiology of some corneal dystrophies...
  15. doi request reprint Pythium insidiosum keratitis in an Australian child
    Paul R Badenoch
    Department of Ophthalmology, Flinders Medical Centre and Flinders University, Bedford Park, South Australia, Australia
    Clin Experiment Ophthalmol 37:806-9. 2009
    ..Although the diagnosis of P. insidiosum keratitis is not difficult, and the organism is susceptible in vitro to a number of antimicrobial agents, early corneal transplantation remains the treatment of choice...
  16. doi request reprint Co-expression of a scFv antibody fragment and a reporter protein using lentiviral shuttle plasmid containing a self-processing furin-2A sequence
    Sarah L Appleby
    Department of Ophthalmology, Flinders University, Adelaide, SA 5042, Australia
    J Immunol Methods 397:61-5. 2013
    ..05). Moreover, protein expression from double-cDNA plasmids was significantly lower than from their corresponding single transgene counterparts (p<0.05). ..
  17. doi request reprint Malignant pleural mesothelioma with associated minimal change disease and acute renal failure
    Jordan Y Z Li
    Department of Renal Medicine, Flinders Medical Centre and Flinders University, Adelaide, South Australia, Australia
    Ren Fail 32:1012-5. 2010
    ..The renal biopsy demonstrated MCD. The underlying pathogenesis of this association remains unknown...
  18. doi request reprint Novel quantitative trait loci for central corneal thickness identified by candidate gene analysis of osteogenesis imperfecta genes
    David P Dimasi
    Department of Ophthalmology, Flinders University, Adelaide, SA 5042, Australia
    Hum Genet 127:33-44. 2010
    ....
  19. doi request reprint ZIC1 is silenced and has tumor suppressor function in malignant pleural mesothelioma
    Yuen Yee Cheng
    Asbestos Diseases Research Institute, University of Sydney, Sydney, Australia Department of Anatomical Pathology, Flinders Medical Centre, Adelaide, Australia Cardiothoracic Surgical Unit, Royal Prince Alfred Hospital The Baird Institute, Sydney Medical School, University of Sydney, Sydney, Australia and Biomedical Research Center, Sir RunRun Shaw Hospital, Zhejiang University, Hangzhou, China
    J Thorac Oncol 8:1317-28. 2013
    ..ZIC1, a potential tumor suppressor gene involved in regulating cell growth and apoptosis, was investigated in MPM cell lines and tumors...
  20. doi request reprint Evaluation of mesoporous silicon/polycaprolactone composites as ophthalmic implants
    Soheila Kashanian
    School of Chemical and Physical Sciences, Flinders University, GPO Box 2100, Adelaide, SA 5001, Australia
    Acta Biomater 6:3566-72. 2010
    ..We suggest that these novel composite materials hold considerable promise as scaffolds in tissue engineering with controlled release applications...
  21. doi request reprint Exposure to cyclic oxygen sufficient for development of oxygen-induced retinopathy does not induce bronchopulmonary dysplasia in rats
    Sonja Klebe
    Department of Anatomical Pathology, Flinders University and Flinders Medical Centre, South Australia, Australia
    Exp Lung Res 36:175-82. 2010
    ....
  22. doi request reprint Identification of LOXL1 protein and Apolipoprotein E as components of surgically isolated pseudoexfoliation material by direct mass spectrometry
    Shiwani Sharma
    Department of Ophthalmology, Flinders University, Bedford Park, South Australia 5042, Australia
    Exp Eye Res 89:479-85. 2009
    ..In conclusion, additional as yet unknown components are present in pathological PEX deposits and mass spectrometry of "isolated" PEX material is an effective strategy for their identification...
  23. ncbi request reprint Prolongation of sheep corneal allograft survival by transfer of the gene encoding ovine IL-12-p40 but not IL-4 to donor corneal endothelium
    Sonja Klebe
    Department of Ophthalmology, Flinders University and Flinders Medical Centre, Adelaide, South Australia, Australia
    J Immunol 175:2219-26. 2005
    ..These findings have important implications for the development of novel strategies to improve human corneal graft survival...
  24. doi request reprint Reduced surface tension normalizes static lung mechanics in a rodent chronic heart failure model
    Dani Louise Dixon
    Intensive and Critical Care Unit, Flinders Medical Centre, Bedford Park, Adelaide, South Australia 5042, Australia
    Am J Respir Crit Care Med 180:181-7. 2009
    ..Chronic elevation of pulmonary microvascular pressure in chronic heart failure results in compensatory changes in the lung that reduce alveolar fluid filtration and protect against pulmonary microvascular rupture...
  25. doi request reprint Resolution of primary acquired melanosis with atypia after minimal mitomycin C treatment
    Jern Yee Chen
    Clin Experiment Ophthalmol 35:865-7. 2007
    ..This case report describes successful treatment of PAM with atypia with a single four day cycle of 0.02% MMC...