Richard H Holloway

Summary

Affiliation: South Australia
Country: Australia

Publications

  1. ncbi request reprint Inhibition of transient lower esophageal sphincter relaxations by electrical acupoint stimulation
    Duowu Zou
    Dept of Gastroenterology, Hepatology, and General Medicine, Royal Adelaide Hospital, North Terrace, Adelaide, SA 5000, Australia
    Am J Physiol Gastrointest Liver Physiol 289:G197-201. 2005
  2. pmc Capsule pH monitoring: is wireless more?
    R H Holloway
    Department of Gastroenterology, Royal Adelaide Hospital, North Terrace, Adelaide, SA 5000, Australia
    Gut 54:1672-3. 2005
  3. doi request reprint The acid pocket and its relevance to reflux disease
    Richard H Holloway
    Department of Gastroenterology and Hepatology, Royal Adelaide Hospital, North Terrace, Adelaide, SA 5000, Australia
    Gut 57:285-6. 2008
  4. doi request reprint Effects of physiological hyperglycemia on duodenal motility and flow events, glucose absorption, and incretin secretion in healthy humans
    Paul Kuo
    Discipline of Medicine, University of Adelaide, Level 6, Eleanor Harrald Building, Royal Adelaide Hospital, Adelaide, Australia
    J Clin Endocrinol Metab 95:3893-900. 2010
  5. doi request reprint Effects of metoclopramide on duodenal motility and flow events, glucose absorption, and incretin hormone release in response to intraduodenal glucose infusion
    Paul Kuo
    Royal Adelaide Hospital, University of Adelaide, Australia
    Am J Physiol Gastrointest Liver Physiol 299:G1326-33. 2010
  6. ncbi request reprint Proximal gastric response to small intestinal nutrients is abnormal in mechanically ventilated critically ill patients
    Nam Q Nguyen
    Department of Gastroenterology, Hepatology and General Medicine, Royal Adelaide Hospital, South Australia
    World J Gastroenterol 12:4383-8. 2006
  7. doi request reprint Disturbed colonic motility contributes to anorectal symptoms and dysfunction after radiotherapy for carcinoma of the prostate
    Eric K Yeoh
    Department of Radiation Oncology, Royal Adelaide Hospital, Adelaide, SA, Australia
    Int J Radiat Oncol Biol Phys 78:773-80. 2010
  8. ncbi request reprint The effects of sedation on gastric emptying and intra-gastric meal distribution in critical illness
    Nam Q Nguyen
    Department of Gastroenterology and Hepatology, Royal Adelaide Hospital, North Terrace, SA 5000, Adelaide, Australia
    Intensive Care Med 34:454-60. 2008
  9. doi request reprint The impact of delaying enteral feeding on gastric emptying, plasma cholecystokinin, and peptide YY concentrations in critically ill patients
    Nam Q Nguyen
    Department of Gastroenterology and Hepatology, Royal Adelaide Hospital, South Australia
    Crit Care Med 36:1469-74. 2008
  10. doi request reprint Pathophysiology and natural history of anorectal sequelae following radiation therapy for carcinoma of the prostate
    Eric K Yeoh
    Department of Radiation Oncology, Royal Adelaide Hospital, Adelaide, Australia
    Int J Radiat Oncol Biol Phys 84:e593-9. 2012

Collaborators

Detail Information

Publications47

  1. ncbi request reprint Inhibition of transient lower esophageal sphincter relaxations by electrical acupoint stimulation
    Duowu Zou
    Dept of Gastroenterology, Hepatology, and General Medicine, Royal Adelaide Hospital, North Terrace, Adelaide, SA 5000, Australia
    Am J Physiol Gastrointest Liver Physiol 289:G197-201. 2005
    ..Electric acupoint stimulation at the Neiguan significantly inhibits the frequency of TLESRs in response to gastric distention in healthy subjects. This effect does not appear to be mediated through mu-opioid receptors...
  2. pmc Capsule pH monitoring: is wireless more?
    R H Holloway
    Department of Gastroenterology, Royal Adelaide Hospital, North Terrace, Adelaide, SA 5000, Australia
    Gut 54:1672-3. 2005
  3. doi request reprint The acid pocket and its relevance to reflux disease
    Richard H Holloway
    Department of Gastroenterology and Hepatology, Royal Adelaide Hospital, North Terrace, Adelaide, SA 5000, Australia
    Gut 57:285-6. 2008
  4. doi request reprint Effects of physiological hyperglycemia on duodenal motility and flow events, glucose absorption, and incretin secretion in healthy humans
    Paul Kuo
    Discipline of Medicine, University of Adelaide, Level 6, Eleanor Harrald Building, Royal Adelaide Hospital, Adelaide, Australia
    J Clin Endocrinol Metab 95:3893-900. 2010
    ....
  5. doi request reprint Effects of metoclopramide on duodenal motility and flow events, glucose absorption, and incretin hormone release in response to intraduodenal glucose infusion
    Paul Kuo
    Royal Adelaide Hospital, University of Adelaide, Australia
    Am J Physiol Gastrointest Liver Physiol 299:G1326-33. 2010
    ..Furthermore, GLP-1 and GIP release increased with metoclopramide, but insulin release paradoxically decreased...
  6. ncbi request reprint Proximal gastric response to small intestinal nutrients is abnormal in mechanically ventilated critically ill patients
    Nam Q Nguyen
    Department of Gastroenterology, Hepatology and General Medicine, Royal Adelaide Hospital, South Australia
    World J Gastroenterol 12:4383-8. 2006
    ..To determine the response of the proximal stomach to small intestinal nutrients in critically ill patients...
  7. doi request reprint Disturbed colonic motility contributes to anorectal symptoms and dysfunction after radiotherapy for carcinoma of the prostate
    Eric K Yeoh
    Department of Radiation Oncology, Royal Adelaide Hospital, Adelaide, SA, Australia
    Int J Radiat Oncol Biol Phys 78:773-80. 2010
    ..To evaluate the role of colonic motility in the pathogenesis of anorectal symptoms and dysfunction after radiotherapy (RT) for carcinoma of the prostate...
  8. ncbi request reprint The effects of sedation on gastric emptying and intra-gastric meal distribution in critical illness
    Nam Q Nguyen
    Department of Gastroenterology and Hepatology, Royal Adelaide Hospital, North Terrace, SA 5000, Adelaide, Australia
    Intensive Care Med 34:454-60. 2008
    ..To evaluate the effects of sedation with morphine and midazolam (M&M) versus propofol on gastric emptying in critically ill patients...
  9. doi request reprint The impact of delaying enteral feeding on gastric emptying, plasma cholecystokinin, and peptide YY concentrations in critically ill patients
    Nam Q Nguyen
    Department of Gastroenterology and Hepatology, Royal Adelaide Hospital, South Australia
    Crit Care Med 36:1469-74. 2008
    ..This study examined the impact of delayed feeding on GE, plasma CCK, and peptide YY (PYY) concentrations in the critically ill...
  10. doi request reprint Pathophysiology and natural history of anorectal sequelae following radiation therapy for carcinoma of the prostate
    Eric K Yeoh
    Department of Radiation Oncology, Royal Adelaide Hospital, Adelaide, Australia
    Int J Radiat Oncol Biol Phys 84:e593-9. 2012
    ..To characterize the prevalence, pathophysiology, and natural history of chronic radiation proctitis 5 years following radiation therapy (RT) for localized carcinoma of the prostate...
  11. ncbi request reprint Proximal gastric motility in critically ill patients with type 2 diabetes mellitus
    Nam Q Nguyen
    Department of Gastroenterology, Royal Adelaide Hospital, North Terrace, Adelaide, SA 5000, Australia
    World J Gastroenterol 13:270-5. 2007
    ..To investigate the proximal gastric motor response to duodenal nutrients in critically ill patients with long-standing type 2 diabetes mellitus...
  12. pmc The relationship between gastric emptying, plasma cholecystokinin, and peptide YY in critically ill patients
    Nam Q Nguyen
    Department of Gastroenterology and Hepatology, Royal Adelaide Hospital, North Terrace, Adelaide, South Australia, 5000
    Crit Care 11:R132. 2007
    ..This study aimed to evaluate the relationship between CCK and PYY concentrations and GE in critical illness...
  13. doi request reprint Diminished functional association between proximal and distal gastric motility in critically ill patients
    Nam Q Nguyen
    Department of Gastroenterology and Hepatology, Royal Adelaide Hospital, North Terrace, SA, Australia
    Intensive Care Med 34:1246-55. 2008
    ..This study examined the effects of critical illness on the relationship between proximal and distal gastric motor activity during fasting and duodenal nutrient stimulation...
  14. doi request reprint Delayed enteral feeding impairs intestinal carbohydrate absorption in critically ill patients
    Nam Q Nguyen
    Department of Gastroenterology and Hepatology, Royal Adelaide Hospital, School of Medicine, University of Adelaide, Adelaide, South Australia
    Crit Care Med 40:50-4. 2012
    ..However, its impact on intestinal absorptive function in critically ill patients is unknown. The aim of this study was to examine the impact of delayed enteral nutrition on small intestinal absorption of 3-O-methyl-glucose...
  15. pmc Fasting and nutrient-stimulated plasma peptide-YY levels are elevated in critical illness and associated with feed intolerance: an observational, controlled study
    Nam Q Nguyen
    Department of Gastroenterology, Hepatology and General Medicine, Royal Adelaide Hospital, North Terracce, Adelaide, 5000, South Australia, Australia
    Crit Care 10:R175. 2006
    ..Peptide YY (PYY) slows gastric emptying. The aim of this study was to determine fasting and nutrient-stimulated plasma PYY concentrations and their relationship to cholecystokinin (CCK) in critically ill patients...
  16. ncbi request reprint Prokinetic therapy for feed intolerance in critical illness: one drug or two?
    Nam Q Nguyen
    Department of Gastroenterology and Hepatology, University of Adelaide, Royal Adelaide Hospital, South Australia
    Crit Care Med 35:2561-7. 2007
    ..To compare the efficacy of combination therapy, with erythromycin and metoclopramide, to erythromycin alone in the treatment of feed intolerance in critically ill patients...
  17. pmc Impact of bolus volume on small intestinal intra-luminal impedance in healthy subjects
    Nam Q Nguyen
    Department of Gastroenterology and Hepatology, Royal Adelaide Hospital, North Terrace, Adelaide 5000, Australia
    World J Gastroenterol 16:2151-7. 2010
    ..To assess the impact of bolus volume on the characteristics of small intestinal (SI) impedance signals...
  18. ncbi request reprint Feed intolerance in critical illness is associated with increased basal and nutrient-stimulated plasma cholecystokinin concentrations
    Nam Q Nguyen
    Department of Gastroenterology, Hepatology, and General Medicine, Royal Adelaide Hospital, Adelaide, South Australia, Australia
    Crit Care Med 35:82-8. 2007
    ..Cholecystokinin (CCK) slows gastric emptying. The aim of this study was to determine plasma CCK concentrations during fasting and in response to small-intestine nutrient infusion in critically ill patients...
  19. doi request reprint Plasma erythromycin concentrations predict feeding outcomes in critically ill patients with feed intolerance
    Nam Q Nguyen
    Department of Gastroenterology, Royal Adelaide Hospital, Adelaide, South Australia, Australia
    Crit Care Med 39:868-71. 2011
    ..This study aimed to evaluate the relationship between plasma erythromycin concentrations and feeding outcomes in critically ill patients...
  20. ncbi request reprint Concurrent duodenal manometric and impedance recording to evaluate the effects of hyoscine on motility and flow events, glucose absorption, and incretin release
    Reawika Chaikomin
    Discipline of Medicine, Royal Adelaide Hospital, North Terrace, Adelaide, SA, Australia
    Am J Physiol Gastrointest Liver Physiol 292:G1099-104. 2007
    ..A reduction in the frequency of duodenal flow events is associated with a decreased rate of glucose absorption and incretin release in healthy subjects...
  21. doi request reprint Hypofractionated versus conventionally fractionated radiotherapy for prostate carcinoma: final results of phase III randomized trial
    Eric E Yeoh
    Department of Radiation Oncology, Royal Adelaide Hospital, Adelaide, Australia
    Int J Radiat Oncol Biol Phys 81:1271-8. 2011
    ..a conventionally fractionated (64 Gy in 32 fractions within 6.5 weeks) dose schedule for radiotherapy (RT) for localized carcinoma of the prostate...
  22. pmc The impact of admission diagnosis on gastric emptying in critically ill patients
    Nam Q Nguyen
    Department of Gastroenterology, Royal Adelaide Hospital, Adelaide, Australia
    Crit Care 11:R16. 2007
    ..This study aimed to evaluate the impact of admission diagnosis on GE in critically ill patients...
  23. doi request reprint Gastric emptying measurement of liquid nutrients using the (13)C-octanoate breath test in critically ill patients: a comparison with scintigraphy
    Nam Q Nguyen
    Department of Gastroenterology and Hepatology, Royal Adelaide Hospital, North Terrace, Adelaide, South Australia 5000, Australia
    Intensive Care Med 39:1238-46. 2013
    ..The (13)C-octanoate breath test ((13)C-OBT) is a simple, non-invasive technique that does not involve radiation exposure...
  24. doi request reprint Relationship between altered small intestinal motility and absorption after abdominal aortic aneurysm repair
    Nam Q Nguyen
    Departments of Gastroenterology and Hepatology, Royal Adelaide Hospital, North Terrace, Adelaide, SA, 5000, Australia
    Intensive Care Med 37:610-8. 2011
    ..This study examines interactions between SI motility, flow and absorption in the first 3 days after surgical repair of abdominal aortic aneurysm (AAA)...
  25. ncbi request reprint Risk of Clostridium difficile diarrhoea in critically ill patients treated with erythromycin-based prokinetic therapy for feed intolerance
    Nam Q Nguyen
    Department of Gastroenterology and Hepatology, Royal Adelaide Hospital, North Terrace, 5000, Adelaide, Australia
    Intensive Care Med 34:169-73. 2008
    ..To determine the incidence of Clostridium difficile (CD) diarrhoea in feed-intolerant, critically ill patients who received erythromycin-based prokinetic therapy...
  26. ncbi request reprint Erythromycin is more effective than metoclopramide in the treatment of feed intolerance in critical illness
    Nam Q Nguyen
    Department of Gastroenterology, Hepatology and General Medicine, Royal Adelaide Hospital, and University Department of Medicine, University of Adelaide, South Australia, Australia
    Crit Care Med 35:483-9. 2007
    ....
  27. ncbi request reprint Mechanisms of gastroesophageal reflux in critically ill mechanically ventilated patients
    Garry Nind
    Department of Gastroenterology, Hepatology and General Medicine, Royal Adelaide Hospital, Adelaide, South Australia, Australia
    Gastroenterology 128:600-6. 2005
    ..The aim of this study was to determine the mechanisms underlying gastroesophageal reflux in mechanically ventilated patients in the intensive care unit...
  28. ncbi request reprint Long-standing type II diabetes mellitus is not a risk factor for slow gastric emptying in critically ill patients
    Nam Q Nguyen
    Department of Gastroenterology, Royal Adelaide Hospital, Adelaide SA, Australia
    Intensive Care Med 32:1365-70. 2006
    ..The effect of DM on the incidence of slow GE in these patients is unknown. We evaluated the effect of DM on liquid GE in critically ill patients...
  29. ncbi request reprint Relationship between pressure wave amplitude and esophageal bolus clearance assessed by combined manometry and multichannel intraluminal impedance measurement
    Nam Q Nguyen
    Department of Gastroenterology, Hepatology and General Medicine, Royal Adelaide Hospital and University of Adelaide, Adelaide, South Australia, Australia
    Am J Gastroenterol 101:2476-84. 2006
    ..The aim of this study was to assess the impact of peristaltic wave amplitude on esophageal volume clearance using multiple intraluminal impedance (MII) measurement...
  30. doi request reprint Anorectal function after three- versus two-dimensional radiation therapy for carcinoma of the prostate
    Eric K Yeoh
    Department of Radiation Oncology, Royal Adelaide Hospital, Adelaide SA, Australia
    Int J Radiat Oncol Biol Phys 73:46-52. 2009
    ..To compare the effects of (three-dimensional) 3D vs. two-dimensional (2D) radiation therapy (RT) for carcinoma of the prostate on the prevalence and pathophysiology of anorectal dysfunction...
  31. doi request reprint Current and future techniques in the evaluation of dysphagia
    Paul Kuo
    Department of Gastroenterology and Hepatology, Royal Adelaide Hospital, Adelaide, South Australia, Australia
    J Gastroenterol Hepatol 27:873-81. 2012
    ..Several new techniques for motility testing have also become available, such as esophageal ultrasound and functional lumen imaging probe, but are currently limited to the research setting...
  32. ncbi request reprint Effect of hyperglycemia on triggering of transient lower esophageal sphincter relaxations
    Qing Zhang
    Dept Gastroenterology, Hepatology and General Medicine, Royal Adelaide Hospital, North Terrace, Adelaide, SA 5000, Australia
    Am J Physiol Gastrointest Liver Physiol 286:G797-803. 2004
    ..Mechanisms underlying the effect remain to be determined. Hyperglycemia may be an important factor contributing to the increased esophageal acid exposure in patients with diabetes mellitus...
  33. ncbi request reprint Hypofractionated versus conventionally fractionated radiation therapy for prostate carcinoma: updated results of a phase III randomized trial
    Eric E Yeoh
    Department of Radiation Oncology, Royal Adelaide Hospital, Adelaide, Australia
    Int J Radiat Oncol Biol Phys 66:1072-83. 2006
    ..a conventionally fractionated (64 Gy/32 fractions/6.5 weeks) dose schedule...
  34. ncbi request reprint Recent developments in esophageal motor disorders
    Nam Q Nguyen
    Department of Gastroenterology, Hepatology and General Medicine, Royal Adelaide Hospital, South Australia
    Curr Opin Gastroenterol 21:478-84. 2005
    ..This review outlines the major developments in these areas...
  35. ncbi request reprint Impact of endoscopic suturing of the gastroesophageal junction on lower esophageal sphincter function and gastroesophageal reflux in patients with reflux disease
    William C E Tam
    Department of Gastroenterology, Hepatology and General Medicine, Royal Adelaide Hospital, Adelaide, South Australia 5000, Australia
    Am J Gastroenterol 99:195-202. 2004
    ..The mechanisms underlying these effects are not well defined. The aims of our study were to determine the impact of endoscopic suturing of the gastroesophageal junction on lower esophageal sphincter (LES) function in patients with GERD...
  36. doi request reprint Beyond acid suppression: new pharmacologic approaches for treatment of GERD
    Paul Kuo
    Department of Gastroenterology and Hepatology, Royal Adelaide Hospital, North Terrace, Adelaide, SA, 5000, Australia
    Curr Gastroenterol Rep 12:175-80. 2010
    ..Macrolide antibiotics (eg, erythromycin) show early promise in a select group of patients with possible reflux associated post-lung transplant problems...
  37. doi request reprint Objective outcomes 14 years after laparoscopic anterior 180-degree partial versus nissen fundoplication: results from a randomized trial
    Joris A Broeders
    Discipline of Surgery, University of Adelaide, Royal Adelaide Hospital, Adelaide, South Australia, Australia
    Ann Surg 258:233-9. 2013
    ..To investigate late objective outcomes 14 years after laparoscopic anterior 180-degree partial versus Nissen fundoplication...
  38. pmc Gastroesophageal reflux disease after diagnostic endoscopy in the clinical setting
    Nora B Zschau
    Nora B Zschau, Jane M Andrews, Richard H Holloway, Mark N Schoeman, William CE Tam, Gerald J Holtmann, Department of Gastroenterology and Hepatology, Royal Adelaide Hospital, Adelaide, SA 5000, Australia
    World J Gastroenterol 19:2514-20. 2013
    ..To investigate the outcome of patients with symptoms of gastroesophageal reflux disease (GERD) referred for endoscopy at 2 and 6 mo post endoscopy...
  39. doi request reprint A pragmatic symptom-based approach
    Paul Kuo
    Department of Gastroenterology and Hepatology, Royal Adelaide Hospital, North Terrace, South Australia, Australia
    Best Pract Res Clin Gastroenterol 24:765-73. 2010
    ..Questionnaires have been developed in order to standardise and improve symptom-based diagnosis, and perform as well as primary care clinicians. These have yet to become mainstream practise but offer great potential...
  40. ncbi request reprint Anorectal dysfunction increases with time following radiation therapy for carcinoma of the prostate
    Eric E K Yeoh
    Department of Radiation Oncology, Royal Adelaide Hospital, Adelaide SA 5000, Australia
    Am J Gastroenterol 99:361-9. 2004
    ..To characterize the prevalence and pathophysiology of anorectal dysfunction up to 2 yr following radiation therapy (RT) for localized carcinoma of the prostate...
  41. doi request reprint Association between clinical manifestations of complicated and uncomplicated peptic ulcer and visceral sensory dysfunction
    Montri Gururatsakul
    Department of Gastroenterology and Hepatology, Royal Adelaide Hospital, Adelaide, SA, Australia
    J Gastroenterol Hepatol 25:1162-9. 2010
    ..The aim of this study was to assess symptom profiles and compare visceral sensory thresholds in patients with bleeding peptic ulcer (BPU) and uncomplicated PUD...
  42. ncbi request reprint The impact of continuous positive airway pressure on the lower esophageal sphincter
    Kelly L Shepherd
    West Australian Sleep Disorders Research Institute, Department of Pulmonary Physiology, Sir Charles Gairdner Hospital, Nedlands, Western Australia 6009, Australia
    Am J Physiol Gastrointest Liver Physiol 292:G1200-5. 2007
    ..The findings suggest CPAP may make the LES less susceptible to reflux by increasing Pb and decreasing the duration of LES relaxation...
  43. ncbi request reprint Defective triggering of secondary peristalsis in patients with non-erosive reflux disease
    Katsuhiko Iwakiri
    Department of Medicine, Division of Gastroenterology, Nippon Medical School, Tokyo, Japan
    J Gastroenterol Hepatol 22:2208-11. 2007
    ..The aim of this study was to evaluate the difference in esophageal motility between patients with non-erosive reflux disease and healthy subjects...
  44. ncbi request reprint Radiofrequency energy delivery to the gastric cardia inhibits triggering of transient lower esophageal sphincter relaxation and gastroesophageal reflux in dogs
    Michael S Kim
    Stanford University Medical Center VA Palo Alto Health Care System, Palo Alto, California, USA
    Gastrointest Endosc 57:17-22. 2003
    ..The study assessed the effect of radiofrequency energy delivery to the gastric cardia on the triggering of transient lower esophageal sphincter relaxations and gastroesophageal reflux in dogs...
  45. ncbi request reprint Transient lower esophageal sphincter relaxations (TLESRs) are the major mechanism of gastroesophageal reflux but are not the cause of reflux disease
    Katsuhiko Iwakiri
    Third Department of Internal Medicine, Nippon Medical School, Tokyo, Japan
    Dig Dis Sci 50:1072-7. 2005
    ..These findings, therefore, indicate that reflux disease is not a disorder of TLESRs and relates more to the proximal extent of the refluxate...
  46. ncbi request reprint Esophageal ultrasonography: A new view on esophageal motility
    Richard H Holloway
    Am J Gastroenterol 102:146-8. 2007
    ..The place of HFIUS in the assessment of esophageal function remains to be determined, but it offers the possibility of greater insights into esophageal physiology as well as clinical esophageal motor disorders...
  47. ncbi request reprint Multichannel intraluminal impedance monitoring in the evaluation of patients with non-obstructive Dysphagia
    José M Conchillo
    Department of Gastroenterology and Hepatology, University Medical Center, Utrecht, The Netherlands
    Am J Gastroenterol 100:2624-32. 2005
    ..The aim of this study was to evaluate the value of the addition of multichannel intraluminal impedance (MII) recording to esophageal manometry in the work-up of patients with NOD...