Research Topics
Genomes and GenesSpecies | Stan GronthosSummaryAffiliation: South Australia Country: Australia Publications
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Publications
The role of the chemokine CXCL12 in osteoclastogenesisStan Gronthos
Mesenchymal Stem Cell Group, Division of Haematology, Institute of Medical and Veterinary Science, Hanson Institute, Adelaide, South Australia, Australia
Trends Endocrinol Metab 18:108-13. 2007..Recent studies have highlighted an emerging role for CXCL12 in the processes of physiological and pathological bone remodelling...
A method to isolate and purify human bone marrow stromal stem cellsStan Gronthos
Mesenchymal Stem Cell Group, Division of Haematology, Institute of Medical and Veterinary Science, Hanson Institute, University of Adelaide, SA, Australia
Methods Mol Biol 449:45-57. 2008....- Methods for the purification and characterization of human adipose-derived stem cellsStan Gronthos
Mesenchymal Stem Cell Group, Department of Haematology, Institute of Medical and Veterinary Science Hanson Institute and Centre for Stem Cell Research, University of Adelaide, Adelaide, SA, Australia
Methods Mol Biol 702:109-20. 2011.... 
Immunomodulatory properties of stem cells from human exfoliated deciduous teethTakayoshi Yamaza
Center for Craniofacial Molecular Biology, University of Southern California School of Dentistry, 2250 Alcazar Street, CSA 103, Los Angeles, CA 90033, USA
Stem Cell Res Ther 1:5. 2010..Herein we have characterized mesenchymal stem cell properties of SHED in comparison to human bone marrow mesenchymal stem cells (BMMSCs)...- Pentosan polysulfate promotes proliferation and chondrogenic differentiation of adult human bone marrow-derived mesenchymal precursor cellsPeter Ghosh
Proteobioactives Pty Ltd, 27 9 Powells Road, Brookvale, New South Wales 2100, Australia
Arthritis Res Ther 12:R28. 2010..This study was undertaken to determine whether the anti-osteoarthritis drug pentosan polysulfate (PPS) influenced mesenchymal precursor cell (MPC) proliferation and differentiation... - Reconstruction of human mandible by tissue engineeringStan Gronthos
Mesenchymal Stem Cell Group, Division of Haematology, Institute of Medical and Veterinary Science, Adelaide 5000, South Australia, Australia
Lancet 364:735-6. 2004 - Molecular and cellular characterisation of highly purified stromal stem cells derived from human bone marrowStan Gronthos
Mesenchymal Stem Cell Group, Division of Haematology, Institute of Medical and Veterinary Science, Adelaide, South Australia, Australia
J Cell Sci 116:1827-35. 2003..Our novel selection protocol provides a means to generate purified populations of BMSSCs for use in a range of different tissue engineering and gene therapy strategies... - Heat shock protein-90 beta is expressed at the surface of multipotential mesenchymal precursor cells: generation of a novel monoclonal antibody, STRO-4, with specificity for mesenchymal precursor cells from human and ovine tissuesStan Gronthos
Mesenchymal Stem Cell Group, University of Adelaide, Adelaide SA 5000, Australia
Stem Cells Dev 18:1253-62. 2009..In addition to identifying an antibody reagent that identifies a highly conserved epitope expressed by MSCs from different species, our study also points to a potential role for Hsp90beta in MSC biology... - A method to isolate and culture expand human dental pulp stem cellsStan Gronthos
Mesenchymal Stem Cell Group, Division of Haematology, Institute of Medical and Veterinary Science Hanson Institute CSCR, University of Adelaide, Adelaide, SA, Australia
Methods Mol Biol 698:107-21. 2011..This process involves the enzymatic digestion of fresh samples of human dental pulp tissue followed by the isolation of DPSC using magnetic bead cell separation, based on their expression of mesenchymal stem cell associated markers... - Targeted disruption of the CXCL12/CXCR4 axis inhibits osteolysis in a murine model of myeloma-associated bone lossPeter Diamond
Myeloma Research Program, Bone and Cancer Laboratories, Division of Haematology, Institute of Medical and Veterinary Science, Hanson Institute and the Department of Medicine, University of Adelaide, Adelaide, Australia
J Bone Miner Res 24:1150-61. 2009..These findings confirm our hypothesis that MM PC-derived CXCL12 stimulates the recruitment and activity of OC, thereby contributing to the formation of MM osteolytic lesions... - TWIST family of basic helix-loop-helix transcription factors mediate human mesenchymal stem cell growth and commitmentSandra Isenmann
Mesenchymal Stem Cell Group, Division of Haematology, Institute of Medical and Veterinary Science Hanson Institute CSCR, University of Adelaide, SA, Australia
Stem Cells 27:2457-68. 2009..These findings implicate the TWIST gene family members as potential mediators of MSC self-renewal and lineage commitment in postnatal skeletal tissues by exerting their effects on genes involved in the early stages of bone development... - Human foreskin fibroblasts exert immunomodulatory properties by a different mechanism to bone marrow stromal/stem cellsNaohisa Wada
Division of Haematology, Institute of Medical and Veterinary Science Hanson Institute CSCR, Adelaide, Australia
Stem Cells Dev 20:647-59. 2011..These results suggest that the HFFs possess immunosuppressive properties, which are mediated by alternate mechanisms to that reported for BMSCs... - Effect of coating Straumann Bone Ceramic with Emdogain on mesenchymal stromal cell hard tissue formationKrzysztof Marek Mrozik
Colgate Australian Clinical Dental Research Centre, Dental School, University of Adelaide, Frome Road Adelaide, South Australia 5005, Australia
Clin Oral Investig 16:867-78. 2012..While used in clinical applications, whether Emdogain and other commercial preparations of EMPs truly possess the capacity to induce the regeneration of bone or other components of the periodontium remains to be established... - A novel monoclonal antibody (STRO-3) identifies an isoform of tissue nonspecific alkaline phosphatase expressed by multipotent bone marrow stromal stem cellsStan Gronthos
Mesenchymal Research Laboratory, Division of Haematology, Institute of Medical and Veterinary Science, Hanson Institute and University of Adelaide, Australia 5000
Stem Cells Dev 16:953-63. 2007..Finally, these studies suggest that antibodies to TNSALP may be used as an effective single marker of enrichment of BMSSCs from various tissues... - Immunomodulatory properties of human periodontal ligament stem cellsNaohisa Wada
Mesenchymal Stem Cell Group, Division of Haematology, Institute of Medical and Veterinary Science Hanson Institute CSCR, University of Adelaide, Adelaide, South Australia, Australia
J Cell Physiol 219:667-76. 2009..These results suggest that PDLSCs, BMSSCs, DPSCs, and GFs possess immunosuppressive properties mediated, in part, by soluble factors, produced by activated PBMNCs. J. Cell. Physiol. 219: 667-676, 2009. (c) 2009 Wiley-Liss, Inc... - EphB/ephrin-B interactions mediate human MSC attachment, migration and osteochondral differentiationAgnieszka Arthur
Mesenchymal Stem Cell Group, Department of Haematology, Institute of Medical and Veterinary Science Hanson Institute and Centre for Stem Cell Research Robinson Institute, University of Adelaide, Adelaide, SA, Australia
Bone 48:533-42. 2011..These observations suggest that EphB/ephrin-B interactions may mediate the recruitment, migration and differentiation of MSC during bone repair... - Reparative effects of allogeneic mesenchymal precursor cells delivered transendocardially in experimental nonischemic cardiomyopathyPeter J Psaltis
Cardiovascular Research Centre, Royal Adelaide Hospital and Department of Medicine, University of Adelaide, Adelaide, Australia
JACC Cardiovasc Interv 3:974-83. 2010..This study set out to evaluate the safety and efficacy of allogeneic bone marrow mesenchymal precursor cells (MPC) delivered by multisegmental, transendocardial implantation in the setting of nonischemic cardiomyopathy (NICM)... - Characterisation and developmental potential of ovine bone marrow derived mesenchymal stem cellsRosa C McCarty
Department of Orthopaedic Surgery, Women s and Children s Hospital, Adelaide, Australia
J Cell Physiol 219:324-33. 2009..The comprehensive characterisation of ovine MSC described herein provides important information for future translational studies involving ovine MSC... - Assessment of myocardial fibrosis by endoventricular electromechanical mapping in experimental nonischemic cardiomyopathyPeter J Psaltis
Department of Medicine and Physiology, University of Adelaide, North Terrace, Adelaide, SA, 5000, Australia
Int J Cardiovasc Imaging 27:25-37. 2011..Pending clinical evaluation, it may therefore have applicability for directing targeted intramyocardial interventions in nonischemic heart disease... - Genomic profiling of mesenchymal stem cellsDanijela Menicanin
Mesenchymal Stem Cell Group, Bone and Cancer Laboratories, Division of Haematology, Institute of Medical and Veterinary Science Hanson Institute and CSCR, University of Adelaide, SA, Australia
Stem Cell Rev 5:36-50. 2009..The present review summarizes studies characterizing the gene expression profile of MSCs... - Identification of a common gene expression signature associated with immature clonal mesenchymal cell populations derived from bone marrow and dental tissuesDanijela Menicanin
Mesenchymal Stem Cell Group, Division of Haematology, Institute of Medical and Veterinary Science Hanson Institute Centre for Stem Cell Research, Robinson Institute, University of Adelaide, Adelaide, Australia
Stem Cells Dev 19:1501-10. 2010..These findings provide a model system for identifying a common molecular fingerprint associated with immature mesenchymal stem-like cells from different organs and implicate a potential role for these genes in MSC growth and development... - Proteomic characterization of mesenchymal stem cell-like populations derived from ovine periodontal ligament, dental pulp, and bone marrow: analysis of differentially expressed proteinsKrzysztof M Mrozik
Colgate Australian Clinical Dental Research Centre, Dental School, The University of Adelaide, Adelaide, Australia
Stem Cells Dev 19:1485-99. 2010..These expression patterns can serve as important tools for the regeneration of particular tissues in future stem cell-based tissue engineering studies using animal models... - The nitrogen-containing bisphosphonate, zoledronic acid, increases mineralisation of human bone-derived cells in vitroBeiqing Pan
Myeloma and Mesenchymal Research Group, Matthew Roberts Foundation Laboratory, Division of Haematology, Institute of Medical and Veterinary Science, Adelaide 5000, Australia
Bone 34:112-23. 2004..These results show that, in addition to its direct effects on OCs, ZOL also directly affects the proliferation and differentiation of human OB-like cells in vitro and may enhance bone formation in vivo... - hTERT transcription is repressed by Cbfa1 in human mesenchymal stem cell populationsSandra Isenmann
Mesenchymal Stem Cell Group, Division of Haematology, Institute of Medical and Veterinary Science University of Adelaide, South Australia, Australia
J Bone Miner Res 22:897-906. 2007..We showed that Cbfa1 acts as a partial repressor of TERT, which may facilitate cellular differentiation... - Concise review: mesenchymal stromal cells: potential for cardiovascular repairPeter J Psaltis
Cardiovascular Research Centre, Royal Adelaide Hospital and Department of Medicine, University of Adelaide, Adelaide, South Australia 5000, Australia
Stem Cells 26:2201-10. 2008.... - Implanted adult human dental pulp stem cells induce endogenous axon guidanceAgnieszka Arthur
Mesenchymal Stem Cell Group, CSCR University of Adelaide, Adelaide, South Australia, Australia
Stem Cells 27:2229-37. 2009..These findings provide the first direct evidence that DPSCs may induce neuroplasticity within a receptive host nervous system... - Comparative assessment of the osteoconductive properties of different biomaterials in vivo seeded with human or ovine mesenchymal stem/stromal cellsAndrew C W Zannettino
Myeloma Research Laboratory, Department of Haematology, Institute of Medical and Veterinary Science, Adelaide, South Australia
Tissue Eng Part A 16:3579-87. 2010..This study demonstrates the differences in bone formation potential between human and ovine MSC in vivo based on the osteoconductive properties of different bioscaffolds currently being used for orthopedic clinical applications... - Twist-1 induces Ezh2 recruitment regulating histone methylation along the Ink4A/Arf locus in mesenchymal stem cellsDimitrios Cakouros
Mesenchymal Stem Cell Group, Department of Haematology, SA Pathology, and Centre for Stem Cell Research, Robinson Institute, University of Adelaide, Adelaide, SA, Australia
Mol Cell Biol 32:1433-41. 2012..These studies for the first time link Twist-1 to histone methylation of the Ink4A/Arf locus by controlling the expression of histone methyltransferases as well as the expression of other bHLH factors... - Hypoxia-inducible factor-2 is a novel regulator of aberrant CXCL12 expression in multiple myeloma plasma cellsSally K Martin
Myeloma Research Program, Division of Haematology, Centre for Cancer Biology SA Pathology and University of Adelaide, Australia
Haematologica 95:776-84. 2010..While the mechanisms responsible for aberrant plasma cell expression of CXCL12 remain to be determined, studies in other systems suggest a role for hypoxia and hypoxia-inducible transcription factors... - A method to isolate, purify, and characterize human periodontal ligament stem cellsKrzysztof Mrozik
Mesenchymal Stem Cell Group, Division of Hematology, Institute of Medical and Veterinary Science Hanson Institute, Adelaide, Australia
Methods Mol Biol 666:269-84. 2010.... - NVP-BEZ235, a dual pan class I PI3 kinase and mTOR inhibitor, promotes osteogenic differentiation in human mesenchymal stromal cellsSally K Martin
Myeloma Research Program, Division of Haematology, Centre for Cancer Biology, SA Pathology, and University of Adelaide, Adelaide, Australia
J Bone Miner Res 25:2126-37. 2010..Taken together, our findings suggest that BEZ235 may be useful in treating PI3K/mTOR-dependent tumors associated with bone loss, such as the hematologic malignancy multiple myeloma... - Human mulipotential mesenchymal/stromal stem cells are derived from a discrete subpopulation of STRO-1bright/CD34 /CD45(-)/glycophorin-A-bone marrow cellsAndrew C W Zannettino
Multiple Myeloma Research Laboratory, Division of Haematology, Institute of Medical and Veterinary Science, Hanson Institute and University of Adelaide, Australia
Haematologica 92:1707-8. 2007..These studies support the view that these are two distinct stem cell compartments in adult bone marrow... - Stromal-derived factor-1 promotes the growth, survival, and development of human bone marrow stromal stem cellsAngela Kortesidis
Mesenchymal Stem Cell Group, Division of Haematology, Institute of Medical and Veterinary Science Hanson Institute, Frome Rd, Adelaide 5000, South Australia, Australia
Blood 105:3793-801. 2005..These studies indicate that the chemokine, SDF-1, may play a role in the maintenance, survival, and osteogenic capacity of immature BMSSC populations... - Tumor angiogenesis is associated with plasma levels of stromal-derived factor-1alpha in patients with multiple myelomaSally K Martin
Myeloma and Mesenchymal Research Group, Matthew Roberts Foundation Laboratory, Division of Haematology, Institute of Medical and Veterinary Science, University of Adelaide, Australia
Clin Cancer Res 12:6973-7. 2006..Therefore, we propose that inhibition of SDF-1alpha may be an effective mechanism by which angiogenesis and osteolysis can be reduced in multiple myeloma patients... - Intramyocardial navigation and mapping for stem cell deliveryPeter J Psaltis
Cardiovascular Research Centre, Department of Cardiology, Royal Adelaide Hospital and the Department of Medicine, University of Adelaide, Adelaide, South Australia, 5000, Australia
J Cardiovasc Transl Res 3:135-46. 2010.... - Home is where the heart is: via the FROUNTAndrew C W Zannettino
Division of Haematology, Institute of Medical and Veterinary Science, Adelaide, South Australia, Australia
Cell Stem Cell 2:513-4. 2008..This process is dependent on the intracellular adaptor molecule FROUNT, which interacts with the chemokine receptor CCR2... - EphB4 enhances the process of endochondral ossification and inhibits remodeling during bone fracture repairAgnieszka Arthur
Mesenchymal Stem Cell Group, Department of Haematology, SA Pathology Adelaide and Centre for Stem Cell Research Robinson Institute, University of Adelaide, Adelaide, Australia
J Bone Miner Res 28:926-35. 2013..Taken together, these observations suggest that EphB4 promotes endochondral ossification while inhibiting osteoclast development during callus formation and may represent a novel drug target for the repair of fractured bones... - Suppression of PDGF-induced PI3 kinase activity by imatinib promotes adipogenesis and adiponectin secretionStephen Fitter
Myeloma Research Laboratory, Bone and Cancer Research Laboratories, Department of Haematology, Institute of Medical and Veterinary Science, Centre for Cancer Biology, SA Pathology, GPO Box 14, Adelaide, South Australia 5000, Australia
J Mol Endocrinol 48:229-40. 2012..Taken together, our results suggest that imatinib increases plasma adiponectin levels by promoting adipogenesis through the suppression of PI3 kinase signalling downstream of PDGFR... - Adult human dental pulp stem cells differentiate toward functionally active neurons under appropriate environmental cuesAgnes Arthur
The Australian Research Council, Centre for the Molecular Genetics of Development, University of Adelaide, Adelaide, Australia
Stem Cells 26:1787-95. 2008..We propose that adult human DPSCs provide a readily accessible source of exogenous stem/precursor cells that have the potential for use in cell-therapeutic paradigms to treat neurological disease... - The therapeutic applications of multipotential mesenchymal/stromal stem cells in skeletal tissue repairAgnieszka Arthur
Mesenchymal Stem Cell Group, Division of Haematology, Institute of Medical and Veterinary Science, Hanson Institute University of Adelaide, Adelaide, South Australia, Australia
J Cell Physiol 218:237-45. 2009..This review will specifically focus on the skeletal regenerative capacity of bone marrow derived MSC alone or in combination with growth factors, biocompatible scaffolds, and following genetic modification... - Elevated serum levels of stromal-derived factor-1alpha are associated with increased osteoclast activity and osteolytic bone disease in multiple myeloma patientsAndrew C W Zannettino
Myeloma and Mesenchymal Research Group, Matthew Roberts Foundation Laboratory and Mesenchymal Stem Cell Group, Division of Haematology, Institute of Medical and Veterinary Science, Hanson Institute, Adelaide, Australia
Cancer Res 65:1700-9. 2005..Therefore, we propose that inhibition of the CXCR4-SDF-1alpha axis may provide an effective means of treatment for MM-induced osteolysis... - Stem cells and periodontal regenerationP Mark Bartold
Colgate Australian Clinical Dental Resource Centre, University of Adelaide, South Australia, Australia
Periodontol 2000 40:164-72. 2006 - Human adult dental pulp stem cells enhance poststroke functional recovery through non-neural replacement mechanismsWai Khay Leong
Centre for Stem Cell Research, Robinson Institute, University of Adelaide, South Australia, Australia
Stem Cells Transl Med 1:177-87. 2012..Functional improvement is more likely to be mediated through DPSC-dependent paracrine effects. This study provides preclinical evidence for the future use of human DPSCs in cell therapy to improve outcome in stroke patients... - Bone marrow stromal stem cells for tissue engineeringStan Gronthos
Mesenchymal Stem Cell Group, Division of Haemotology, Institute of Medical and Veterinary Science, Adelaide, South Australia, Australia
Periodontol 2000 41:188-95. 2006 - Application of autologous bone marrow derived mesenchymal stem cells to an ovine model of growth plate cartilage injuryRosa C McCarty
Department of Orthopaedic Surgery, Women s and Children s Hospital, Adelaide, Australia
Open Orthop J 4:204-10. 2010..The current study represents the first work that has utilised this ovine large animal model to investigate whether autologous bone marrow derived MSC can be used to initiate regeneration at the injured growth plate... - EphB/ephrin-B interaction mediates adult stem cell attachment, spreading, and migration: implications for dental tissue repairAgnieszka Stokowski
Australian Research Council, Centre for the Molecular Genetics of Development, University of Adelaide, Adelaide, South Australia, Australia
Stem Cells 25:156-64. 2007..These results may have implications for dental pulp development and regeneration... - Epithelial cell rests of Malassez contain unique stem cell populations capable of undergoing epithelial-mesenchymal transitionJimin Xiong
Colgate Australian Clinical Dental Research Centre, Dental School, University of Adelaide, Adelaide, South Australia, Australia
Stem Cells Dev 21:2012-25. 2012.... - An ovine model of toxic, nonischemic cardiomyopathy--assessment by cardiac magnetic resonance imagingPeter J Psaltis
Cardiovascular Research Centre, Royal Adelaide Hospital Departments of Medicine and Physiology, The University of Adelaide, Adelaide, Australia
J Card Fail 14:785-95. 2008..We set out to validate an ovine model of doxorubicin-induced cardiomyopathy, using cardiac magnetic resonance (CMR) to assess cardiac function... - RANKL expression is related to the differentiation state of human osteoblastsGerald J Atkins
Department of Orthopaedics and Trauma, University of Adelaide, Adelaide, South Australia, Australia
J Bone Miner Res 18:1088-98. 2003..Additionally, the dual roles of osteoblasts, in supporting osteoclastogenesis or forming bone, may be performed by the same lineage of cells at different stages of their maturation... - A crucial role of caspase-3 in osteogenic differentiation of bone marrow stromal stem cellsMasako Miura
Craniofacial and Skeletal Diseases Branch, National Institute of Dental and Craniofacial Research NIDCR, NIH, Bethesda, MD 20892, USA
J Clin Invest 114:1704-13. 2004..This study demonstrates that caspase-3 is crucial for the differentiation of BMSSCs by influencing TGF-beta/Smad2 pathway and cell cycle progression... - Bone formation by human postnatal bone marrow stromal stem cells is enhanced by telomerase expressionSongtao Shi
Craniofacial and Skeletal Diseases Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD 20892, USA
Nat Biotechnol 20:587-91. 2002..These results show that telomerase expression can overcome critical technical barriers to the ex vivo expansion of BMSSCs, and suggest that telomerase therapy may be a useful strategy for bone regeneration and repair... - Mesenchymal stem cell-organized bone marrow elements: an alternative hematopoietic progenitor resourceYasuo Miura
National Institute of Dental and Craniofacial Research, NIH, Bethesda, Maryland
Stem Cells 24:2428-36. 2006..These results indicate that the BMMSC-organized BM niche system represents a unique hematopoietic progenitor resource possessing potential clinical value... - Perivascular niche of postnatal mesenchymal stem cells in human bone marrow and dental pulpSongtao Shi
Craniofacial and Skeletal Diseases Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, USA
J Bone Miner Res 18:696-704. 2003.... - Telomerase accelerates osteogenesis of bone marrow stromal stem cells by upregulation of CBFA1, osterix, and osteocalcinStan Gronthos
Craniofacial and Skeletal Diseases Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland 20892, USA
J Bone Miner Res 18:716-22. 2003..Taken together, these findings show that telomerase can accelerate cell cycle progression from G1-to-S phase and enhance osteogenic differentiation of BMSSCs, because of the upregulation of CBFA1, osterix, and osteocalcin... - Investigation of multipotent postnatal stem cells from human periodontal ligamentByoung-Moo Seo
Craniofacial and Skeletal Diseases Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA
Lancet 364:149-55. 2004..Transplantation of these cells, which can be obtained from an easily accessible tissue resource and expanded ex vivo, might hold promise as a therapeutic approach for reconstruction of tissues destroyed by periodontal diseases... - SHED: stem cells from human exfoliated deciduous teethMasako Miura
Craniofacial and Skeletal Diseases Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD 20892, USA
Proc Natl Acad Sci U S A 100:5807-12. 2003..Thus, exfoliated teeth may be an unexpected unique resource for stem-cell therapies including autologous stem-cell transplantation and tissue engineering... - Defective osteogenesis of the stromal stem cells predisposes CD18-null mice to osteoporosisYasuo Miura
Department of Physiology, University of Maryland School of Medicine, Rockville, MD 20855, USA
Proc Natl Acad Sci U S A 102:14022-7. 2005..Altogether, this work demonstrates that CD18 functions critically in the osteogenesis of BMSSCs, and thus lack of CD18 expression in the leukocyte adhesion deficiency patients may predispose them to osteoporosis... - Pharmacologic stem cell based intervention as a new approach to osteoporosis treatment in rodentsTakayoshi Yamaza
Center for Craniofacial Molecular Biology, University of Southern California School of Dentistry, Los Angeles, California, United States of America
PLoS ONE 3:e2615. 2008.... - Dental pulp stem cellsHe Liu
Peking University School of Stomatology, Beijing, China
Methods Enzymol 419:99-113. 2006..In this review, we introduce methodologies for isolating postnatal stem cells from human dental pulp and discuss their potential role in tissue regeneration... - Circulating connective tissue precursors: extreme rarity in humans and chondrogenic potential in guinea pigsSergei A Kuznetsov
Craniofacial Research and Skeletal Diseases Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland 20892 4370, USA
Stem Cells 25:1830-9. 2007..Disclosure of potential conflicts of interest is found at the end of this article... - Mesenchymal lineage precursor cells induce vascular network formation in ischemic myocardiumTimothy P Martens
Division of Cardiothoracic Surgery, Columbia University, New York, NY, USA
Nat Clin Pract Cardiovasc Med 3:S18-22. 2006..Intramyocardial injection of human STRO-1-selected precursors in an athymic rat model of acute myocardial infarction results in induction of vascular network formation and arteriogenesis coupled with global functional cardiac recovery...