L D Smythe

Summary

Country: Australia

Publications

  1. pmc A quantitative PCR (TaqMan) assay for pathogenic Leptospira spp
    Lee D Smythe
    WHO FAO OIE Collaborating Centre for Reference and Research on Leptospirosis, Centre for Public Health Sciences, Queensland Health Scientific Services, Brisbane, Australia
    BMC Infect Dis 2:13. 2002
  2. ncbi request reprint Molecular typing of Leptospira spp. based on putative O-antigen polymerase gene (wzy), the benefit over 16S rRNA gene sequence
    Piyada Wangroongsarb
    Department of Microbiology and Immunology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    FEMS Microbiol Lett 271:170-9. 2007
  3. pmc Emergence of new leptospiral serovars in American Samoa - ascertainment or ecological change?
    Colleen L Lau
    School of Population Health, The University of Queensland, Herston, Queensland, 4006, Australia
    BMC Infect Dis 12:19. 2012
  4. pmc Identification of pathogenic Leptospira species by conventional or real-time PCR and sequencing of the DNA gyrase subunit B encoding gene
    Andrew T Slack
    WHO FAO OIE Collaborating Centre for Reference and Research on Leptospirosis, Centre for Public Health Sciences, Queensland Health Scientific Services, Brisbane, Australia
    BMC Microbiol 6:95. 2006
  5. pmc Leptospirosis in the Asia Pacific region
    Ann Florence B Victoriano
    Department of Medical Microbiology, University of the Philippines, College of Public Health, Manila, Philippines
    BMC Infect Dis 9:147. 2009
  6. pmc Development of a Multiple-Locus Variable Number of Tandem Repeat Analysis (MLVA) for Leptospira interrogans and its application to Leptospira interrogans serovar Australis isolates from Far North Queensland, Australia
    Andrew T Slack
    WHO FAO OIE Collaborating Centre for Reference and Research on Leptospirosis, Centre for Public Health Sciences, Queensland Health Scientific Services, Brisbane, Australia
    Ann Clin Microbiol Antimicrob 4:10. 2005
  7. ncbi request reprint Leptospiral antibodies in flying foxes in Australia
    L D Smythe
    WHO FAO Collaborating Centre for Reference and Research on Leptospirosis, Queensland Health Scientific Services, Kessels Road, Coopers Plains, Queensland 4108, Australia
    J Wildl Dis 38:182-6. 2002
  8. ncbi request reprint Review of leptospirosis notifications in Queensland and Australia: January 1998-June 1999
    L Smythe
    WHO FAO Collaborating Centre for Reference and Research on Leptospirosis, Queensland, Australia
    Commun Dis Intell 24:153-7. 2000
  9. doi request reprint High-resolution melt-curve analysis of random amplified polymorphic DNA (RAPD-HRM) for the characterisation of pathogenic leptospires: intra-serovar divergence, inter-serovar convergence, and evidence of attenuation in Leptospira reference collections
    S M Tulsiani
    The University of Queensland, School of Veterinary Science, St Lucia, Queensland, 4072, Australia
    Ann Trop Med Parasitol 104:427-37. 2010
  10. doi request reprint The role of fruit bats in the transmission of pathogenic leptospires in Australia
    S M Tulsiani
    School of Veterinary Science, The University of Queensland, Gatton, Queensland, Australia
    Ann Trop Med Parasitol 105:71-84. 2011

Collaborators

  • Scott B Craig
  • S M Tulsiani
  • H E Field
  • R L Galloway
  • Ina L Smith
  • B G Corney
  • A T Slack
  • M Cinco
  • R N Cobbold
  • Wirongrong Chierakul
  • Y Suputtamongkol
  • Vanaporn Wuthiekanun
  • Michael F Dohnt
  • Sharon J Peacock
  • Meegan L Symonds
  • Colleen L Lau
  • Ann Florence B Victoriano
  • Jutta Eymann
  • Piyada Wangroongsarb
  • Philip Weinstein
  • P F Black
  • Chris Skelly
  • Lolita L Cavinta
  • Nina Gloriani-Barzaga
  • Shin ichi Yoshida
  • Ben Adler
  • Gyanendra Gongal
  • M F Dohnt
  • M A Norris
  • Yasutake Yanagihara
  • Caroline Anne Coulombe
  • Takeshi Kasai
  • M L Symonds
  • Bee Lee Ong
  • Julie Hall
  • Khanchit Limpakarnjanarat
  • Prayad Daengsupa
  • Thareerat Kalambaheti
  • Catherine A Herbert
  • Dieter M Bulach
  • Desmond W Cooper
  • Janjira Thaipadungpanit
  • Stuart D Blacksell
  • Pedcharat Satheanmethakul
  • Siriporn Jetanadee
  • Vannaporn Wuthiekanun
  • Nicholas P Day
  • Nicholas P J Day
  • Do Hoang Long
  • Amornwadee Sangkakam
  • Kata Gunlabun
  • Direk Limmathurotsakul
  • Prangyong Sakaraserane
  • Nisa Sirisukkarn
  • Leonie J Barnett
  • Nicholas J White
  • Roongreung Limpaiboon
  • Teerarut Chanket
  • T H Woo
  • B K Patel

Detail Information

Publications28

  1. pmc A quantitative PCR (TaqMan) assay for pathogenic Leptospira spp
    Lee D Smythe
    WHO FAO OIE Collaborating Centre for Reference and Research on Leptospirosis, Centre for Public Health Sciences, Queensland Health Scientific Services, Brisbane, Australia
    BMC Infect Dis 2:13. 2002
    ....
  2. ncbi request reprint Molecular typing of Leptospira spp. based on putative O-antigen polymerase gene (wzy), the benefit over 16S rRNA gene sequence
    Piyada Wangroongsarb
    Department of Microbiology and Immunology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    FEMS Microbiol Lett 271:170-9. 2007
    ....
  3. pmc Emergence of new leptospiral serovars in American Samoa - ascertainment or ecological change?
    Colleen L Lau
    School of Population Health, The University of Queensland, Herston, Queensland, 4006, Australia
    BMC Infect Dis 12:19. 2012
    ....
  4. pmc Identification of pathogenic Leptospira species by conventional or real-time PCR and sequencing of the DNA gyrase subunit B encoding gene
    Andrew T Slack
    WHO FAO OIE Collaborating Centre for Reference and Research on Leptospirosis, Centre for Public Health Sciences, Queensland Health Scientific Services, Brisbane, Australia
    BMC Microbiol 6:95. 2006
    ..In addition 50 unidentified Leptospira isolates were characterised by gyrB sequencing and compared with conventional 16s rRNA sequencing...
  5. pmc Leptospirosis in the Asia Pacific region
    Ann Florence B Victoriano
    Department of Medical Microbiology, University of the Philippines, College of Public Health, Manila, Philippines
    BMC Infect Dis 9:147. 2009
    ..It describes the current trends in the epidemiology of leptospirosis, the existing surveillance systems, and presents the existing prevention and control programs in the Asia Pacific region...
  6. pmc Development of a Multiple-Locus Variable Number of Tandem Repeat Analysis (MLVA) for Leptospira interrogans and its application to Leptospira interrogans serovar Australis isolates from Far North Queensland, Australia
    Andrew T Slack
    WHO FAO OIE Collaborating Centre for Reference and Research on Leptospirosis, Centre for Public Health Sciences, Queensland Health Scientific Services, Brisbane, Australia
    Ann Clin Microbiol Antimicrob 4:10. 2005
    ..Current methodologies used for typing Leptospira have significant drawbacks. The development of an easy to perform yet high resolution method is needed for this organism...
  7. ncbi request reprint Leptospiral antibodies in flying foxes in Australia
    L D Smythe
    WHO FAO Collaborating Centre for Reference and Research on Leptospirosis, Queensland Health Scientific Services, Kessels Road, Coopers Plains, Queensland 4108, Australia
    J Wildl Dis 38:182-6. 2002
    ..The potential exists for establishment of infection in new host species, the transmission of new serovars to known host species, and for changes in virulence of leptospires as a result of passage through these species...
  8. ncbi request reprint Review of leptospirosis notifications in Queensland and Australia: January 1998-June 1999
    L Smythe
    WHO FAO Collaborating Centre for Reference and Research on Leptospirosis, Queensland, Australia
    Commun Dis Intell 24:153-7. 2000
    ..Serovar zanoni continues to be a major cause of severe clinical leptospirosis. Several cases were diagnosed in tourists. One of these cases presented with severe respiratory distress and required 14 days in hospital...
  9. doi request reprint High-resolution melt-curve analysis of random amplified polymorphic DNA (RAPD-HRM) for the characterisation of pathogenic leptospires: intra-serovar divergence, inter-serovar convergence, and evidence of attenuation in Leptospira reference collections
    S M Tulsiani
    The University of Queensland, School of Veterinary Science, St Lucia, Queensland, 4072, Australia
    Ann Trop Med Parasitol 104:427-37. 2010
    ..Further, RAPD-HRM analysis of reference strains indicates that the routine renewal of reference collections, with new isolates, may be needed to maintain the genetic integrity of the collections...
  10. doi request reprint The role of fruit bats in the transmission of pathogenic leptospires in Australia
    S M Tulsiani
    School of Veterinary Science, The University of Queensland, Gatton, Queensland, Australia
    Ann Trop Med Parasitol 105:71-84. 2011
    ..Stringent quantitative risk analysis of the present and similar data, to explore their implications in terms of disease prevalence and wildlife population dynamics, is recommended...
  11. doi request reprint High-resolution melt-curve analysis of random-amplified-polymorphic-DNA markers, for the characterisation of pathogenic Leptospira
    S M Tulsiani
    The University of Queensland, School of Veterinary Science, St Lucia, Queensland, Australia
    Ann Trop Med Parasitol 104:151-61. 2010
    ..As an objective and relatively inexpensive and rapid method of serovar identification, at least for cultured isolates, RAPD-HRM assays show convincing potential...
  12. doi request reprint Emerging tropical diseases in Australia. Part 1. Leptospirosis
    S M Tulsiani
    WHO OIE FAO Collaborating Centre for Reference and Research on Leptospirosis, Communicable Diseases Unit, Queensland Health Forensic and Scientific Services, P O Box 594, Archerfield, Queensland, 4108, Australia
    Ann Trop Med Parasitol 104:543-56. 2010
    ..This information should furnish clinicians with an updated tool to help overcome a number of problems associated with the diagnosis of leptospirosis...
  13. ncbi request reprint Prevalence of antibodies of Leptospira serovars in beef cattle in central Queensland
    P F Black
    Department of Primary Industries, Brisbane, GPO Box 46, Brisbane, Queensland 4105
    Aust Vet J 79:344-8. 2001
    ..The data suggest that serovars other than hardjo, pomona and tarassovi, are unlikely to have a significant role in bovine subfertility and that cattle are unlikely to be a source of human infection with them in central Queensland...
  14. doi request reprint Leptospirosis and Goodpasture's syndrome: testing the aetiological hypothesis
    S B Craig
    WHO OIE FAO Collaborating Centre for Reference and Research on Leptospirosis, Communicable Diseases Unit, Queensland Health Forensic and Scientific Service, Archerfield, Queensland 4108, Australia
    Ann Trop Med Parasitol 103:647-51. 2009
    ....
  15. doi request reprint Hypomagnesaemia in the first 10 days of severe leptospirosis
    S B Craig
    WHO OIE FAO Collaborating Centre for Reference and Research on Leptospirosis, Archerfield, Queensland, Australia
    Ann Trop Med Parasitol 103:705-9. 2009
    ..Any hypomagnesaemia can then be treated promptly, in an effort to reduce the morbidity and mortality attributable to the disease...
  16. ncbi request reprint Real-time homogeneous assay of rapid cycle polymerase chain reaction product for identification of Leptonema illini
    T H Woo
    School of Biomolecular and Biomedical Sciences, Faculty of Science, Griffith University, Brisbane, Queensland, Australia
    Anal Biochem 259:112-7. 1998
    ....
  17. pmc The epidemiology of leptospirosis and the emergence of Leptospira borgpetersenii serovar Arborea in Queensland, Australia, 1998-2004
    A T Slack
    WHO FAO OIE Collaborating Centre for Reference and Research on Leptospirosis, Western Pacific Region, Centre for Public Health Sciences, Queensland Health Scientific Services, Brisbane, Australia
    Epidemiol Infect 134:1217-25. 2006
    ..Assessment of epidemiological trends in leptospirosis is important to obtain directed public health intervention and outcomes in the reduction of leptospirosis cases...
  18. doi request reprint Haematological and clinical-chemistry markers in patients presenting with leptospirosis: a comparison of the findings from uncomplicated cases with those seen in the severe disease
    S B Craig
    WHO FAO OIE Collaborating Centre for Reference and Research on Leptospirosis, Communicable Diseases Unit, Queensland Health Forensic and Scientific Services, P O Box 594, Archerfield, Queensland, 4108, Australia
    Ann Trop Med Parasitol 103:333-41. 2009
    ..Investigations into the use of albumin treatments, which might significantly improve the clinical care of patients with acute leptospirosis, appear to be justified...
  19. doi request reprint Lymphopenia is observed regularly in the acute (leptospiraemic) phase but not the immune phase of leptospirosis
    Scott B Craig
    WHO OIE FAO Collaborating Centre for Reference and Research on Leptospirosis, Communicable Diseases Unit, Queensland Health Forensic and Scientific Service, Archerfield, Queensland 4108, Australia scott
    Trans R Soc Trop Med Hyg 103:958-60. 2009
    ..Statistical differences in lymphocyte counts were observed between the three groups. In conclusion, this study has shown that the phase of leptospiral infection may affect patient lymphocyte counts...
  20. doi request reprint Reclassification of Leptospira meyeri serovar Perameles to Leptospira interrogans serovar Perameles through serological and molecular analysis: evidence of a need for changes to current procedures in Leptospira taxonomy
    Andrew T Slack
    WHO FAO OIE Collaborating Centre for Reference and Research on Leptospirosis, Australia
    Int J Syst Evol Microbiol 59:1199-203. 2009
    ..interrogans. This reclassification highlights a need for changes to how reference Leptospira serovars are identified, disseminated and stored, with the aim of reducing heterogeneity of reference strains between culture collections...
  21. pmc Molecular epidemiology of Leptospira borgpetersenii serovar Arborea, Queensland, Australia, 1998-2005
    Andrew T Slack
    WHO FAO OIE Collaborating Centre for Reference and Research on Leptospirosis, Western Pacific Region, Communicable Disease Unit, Queensland Health Forensic and Scientific Services, Coopers Plains, Queensland, Australia
    Am J Trop Med Hyg 83:820-1. 2010
    ..There was clonality among rodent isolates from geographically related areas. This study highlights the utility of Leptospira culture combined with FAFLP for the examination of the epidemiology of this disease...
  22. doi request reprint Leptospira kmetyi sp. nov., isolated from an environmental source in Malaysia
    Andrew T Slack
    WHO FAO OIE Collaborating Centre for Reference and Research on Leptospirosis, Western Pacific Region, Communicable Diseases, Queensland Health Forensic and Scientific Services, Brisbane, Australia
    Int J Syst Evol Microbiol 59:705-8. 2009
    ..nov. is proposed. The type strain is Bejo-Iso9(T) (=WHO LT1101(T)=KIT Bejo-Iso9(T))...
  23. doi request reprint Leptospira wolffii sp. nov., isolated from a human with suspected leptospirosis in Thailand
    Andrew T Slack
    WHO FAO OIE Collaborating Centre for Reference and Research on Leptospirosis, Western Pacific Region, Communicable Diseases, Queensland Health Forensic and Scientific Services, Brisbane, Australia
    Int J Syst Evol Microbiol 58:2305-8. 2008
    ..nov. is proposed. The type strain is Khorat-H2(T) (=WHO LT1686(T) =KIT Khorat-H2(T))...
  24. ncbi request reprint Epidemiology of Leptospira weilii serovar Topaz infections in Australia
    Andrew T Slack
    WHO FAO OIE Collaborating Centre for Reference and Research on Leptospirosis, Western Pacific Region, Centre for Public Health Sciences, Queensland Health Scientific Services, Brisbane
    Commun Dis Intell 31:216-22. 2007
    ..weilii sv. Topaz isolates including 2 animal isolates. Clustering analysis grouped the 15 isolates into 5 main clades with 13 unique FAFLP profiles. A high level of relatedness was demonstrated between 2 animal and 2 human isolates...
  25. doi request reprint The microscopic agglutination test (MAT) is an unreliable predictor of infecting Leptospira serovar in Thailand
    Lee D Smythe
    WHO FAO OIE Collaborating Centre for Reference and Research on Leptospirosis, Western Pacific Region, Communicable Disease Unit, Queensland Health Scientific Services, Brisbane, Australia
    Am J Trop Med Hyg 81:695-7. 2009
    ..MAT correctly determined the infecting serovar in 26 cases (33%), indicating that this assay is a poor predictor of infecting serovar in our setting...
  26. ncbi request reprint Leptospirosis serology in the common brushtail possum (Trichosurus vulpecula) from urban Sydney, Australia
    Jutta Eymann
    Macquarie University, Department of Biological Sciences, North Ryde, New South Wales 2109, Australia
    J Wildl Dis 43:492-7. 2007
    ..These data support the possible role of brushtail possums as a maintenance host for Leptospira spp. in urban environments and also identified them as a previously unknown and potential source of serovar Arborea...
  27. pmc Clinical diagnosis and geographic distribution of leptospirosis, Thailand
    Vanaporn Wuthiekanun
    Mahidol University, Bangkok, Thailand
    Emerg Infect Dis 13:124-6. 2007
    ..Accuracy of clinical diagnosis varied from 0% to 50% between the provinces and was highest during the rainy season. Most confirmed cases occurred in the north and northeast regions of the country...
  28. pmc Optimization of culture of Leptospira from humans with leptospirosis
    Vanaporn Wuthiekanun
    Faculty of Tropical Medicine, Mahidol University, 420 6 Rajvithi Road, Bangkok 10400, Thailand
    J Clin Microbiol 45:1363-5. 2007
    ....