Research Topics
| Ian W SaundersSummaryCountry: Australia Publications
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Detail Information
Publications
A range of simple summary genome-wide statistics for detecting genetic linkage using high density marker dataIan W Saunders
CSIRO Preventative Health National Research Flagship, CSIRO Mathematical and Information Sciences, Glen Osmond 5064, Australia
Genet Epidemiol 31:565-76. 2007..While the sample size was not sufficient to detect the linkage, there was a clear signal at the MLH1 location indicating that relatively small sample sizes would have been adequate to detect linkage to this gene...
Estimating genotyping error rates from Mendelian errors in SNP array genotypes and their impact on inferenceIan W Saunders
Preventative Health National Research Flagship, Private Bag No 2, Glen Osmond, SA 5064, Australia
Genomics 90:291-6. 2007..Simulated data are used to show that the number of SNPs on this array is sufficient for such a low error rate to have little impact on identical by descent-based inference for disease linkage in sib-pair studies...
Assessing the potential usefulness of IGF-related peptides and adiponectin for predicting disease riskDamien P Belobrajdic
CSIRO, Preventative Health National Research Flagship, P O Box 10041, Adelaide, BC 5000, Australia
Growth Horm IGF Res 18:198-204. 2008..The purpose of this study was to use the D-value to predict the potential usefulness of IGF-related peptides and adiponectin as biomarkers for the diagnosis of colorectal cancer (CRC)...
A measure of the performance of biomarkers for diseaseIan W Saunders
CSIRO Mathematical and Information Sciences, Glen Osmond, Australia
Cancer Biomark 2:145-50. 2006..The impact of within-individual and between-individual variation in biomarker levels is also evaluated. An approach to the choice of sample size for experiments to estimate D is described...
