Research Topics
| Leon J WorthSummaryAffiliation: Royal Melbourne Hospital Country: Australia Publications
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Detail Information
Publications
Impact of revising the National Nosocomial Infection Surveillance System definition for catheter-related bloodstream infection in ICU: reproducibility of the National Healthcare Safety Network case definition in an Australian cohort of infection control pLeon J Worth
Victorian Hospital Acquired Infection Surveillance System VICNISS Coordinating Centre, North Melbourne, Victoria, Australia
Am J Infect Control 37:643-8. 2009..Effective and comparable surveillance for central venous catheter-related bloodstream infections (CLABSIs) in the intensive care unit requires a reproducible case definition that can be readily applied by infection control professionals...
Validation of statewide surveillance system data on central line-associated bloodstream infection in intensive care units in AustraliaEmma S McBryde
Victorian Infectious Diseases Service, Centre for Clinical Research Excellence in Infectious Diseases, Royal Melbourne Hospital, Melbourne, Victoria, Australia
Infect Control Hosp Epidemiol 30:1045-9. 2009....
Surveillance for catheter-associated bloodstream infection in hematology units: quantifying the characteristics of a practical case definitionLeon J Worth
Department of Infectious Diseases, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia
Infect Control Hosp Epidemiol 29:358-60. 2008..0% sensitivity and 94.3% specificity. This case definition provides a practical method for effectively excluding CVC-associated bloodstream infection...
Infective and thrombotic complications of central venous catheters in patients with hematological malignancy: prospective evaluation of nontunneled devicesLeon J Worth
Centre for Clinical Research Excellence in Infectious Disease, Victorian Infectious Diseases Service, Royal Melbourne Hospital, Parkville, Victoria, 3052, Australia
Support Care Cancer 17:811-8. 2009..The objectives of this study were to determine the natural history and rate of CVC-related complications and risk factors for CR-BSI and to compare device-specific complications in a hematology population...
Bloodstream infections in haematology: risks and new challenges for preventionLeon J Worth
Department of Infectious Diseases, Peter MacCallum Cancer Centre, Victoria, Australia
Blood Rev 23:113-22. 2009..To reduce the rate and impact of bloodstream infections multifaceted and customised strategies are required within individual haematology units...
Use of FDG PET/CT for investigation of febrile neutropenia: evaluation in high-risk cancer patientsStephen D Guy
Department of Infectious Diseases, Western Health, Private Bag, Footscray, Victoria, Australia 3011
Eur J Nucl Med Mol Imaging 39:1348-55. 2012..The aim of this study was to prospectively evaluate the clinical utility of FDG PET/CT in patients with cancer and severe neutropenia and five or more days of persistent fever despite antibiotic therapy...
Prophylactic intravenous immunoglobulin during autologous haemopoietic stem cell transplantation for multiple myeloma is not associated with reduced infectious complicationsPiers Blombery
Division of Cancer Medicine, Peter MacCallum Cancer Centre, East Melbourne, Melbourne, Victoria, Australia
Ann Hematol 90:1167-72. 2011..4 g/kg) to reduce infectious complications in a large cohort of patients with myeloma undergoing ASCT. In the absence of data supporting efficacy in this context, there appears to be no benefit in the routine use of IVIG for this purpose...
Impact of vancomycin surgical antibiotic prophylaxis on the development of methicillin-sensitive staphylococcus aureus surgical site infections: report from Australian Surveillance Data (VICNISS)Ann L Bull
Victorian Healthcare Associated Surveillance System VICNISS Coordinating Centre, North Melbourne, Australia
Ann Surg 256:1089-92. 2012..To compare risks for developing surgical site infection (SSI) due to Staphylococcus aureus when vancomycin is used for antibiotic prophylaxis with risks when a β-lactam antibiotic is administered for prophylaxis...
Stenotrophomonas maltophilia: emerging disease patterns and challenges for treatmentIain J Abbott
Department of Infectious Diseases, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia
Expert Rev Anti Infect Ther 9:471-88. 2011..Finally, measures to prevent transmission of S. maltophilia within healthcare facilities are reported, especially in at-risk patient populations...
Catheter-related bloodstream infections in hematology: time for standardized surveillance?Leon J Worth
Centre for Clinical Research Excellence in Infectious Disease, Victorian Infectious Diseases Service, Royal Melbourne Hospital, Parkville, Victoria, Australia
Cancer 109:1215-26. 2007..Only when these issues are addressed can a surveillance strategy reliably assess trends and compare data, leading to improved patient outcomes and a reduction in healthcare expenditure for patients with hematologic malignancy...
