D Velakoulis

Summary

Affiliation: Royal Melbourne Hospital
Country: Australia

Publications

  1. doi request reprint Hippocampal pathology in individuals at ultra-high risk for psychosis: a multi-modal magnetic resonance study
    Stephen J Wood
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne and Melbourne Health, Parkville, Vic, Australia
    Neuroimage 52:62-8. 2010
  2. ncbi request reprint Conn's dementia
    Dennis Velakoulis
    Neuropsychiatry Unit, Royal Melbourne Hospital, Parkville, Vic, Australia
    Lancet Neurol 1:131. 2002
  3. ncbi request reprint Hippocampal and amygdala volumes according to psychosis stage and diagnosis: a magnetic resonance imaging study of chronic schizophrenia, first-episode psychosis, and ultra-high-risk individuals
    Dennis Velakoulis
    Melbourne Neuropsychiatry Centre and Department of Psychiatry, University of Melbourne, Australia
    Arch Gen Psychiatry 63:139-49. 2006
  4. doi request reprint Abnormal hippocampal distribution of TDP-43 in patients with-late onset psychosis
    Dennis Velakoulis
    Neuropsychiatry Unit, Royal Melbourne Hospital, Vic, Australia
    Aust N Z J Psychiatry 43:739-45. 2009
  5. doi request reprint Frontotemporal dementia presenting as schizophrenia-like psychosis in young people: clinicopathological series and review of cases
    D Velakoulis
    Neuropsychiatry Unit, Level 2 John Cade Building, Royal Melbourne Hospital, Parkville, Victoria 3052, Australia
    Br J Psychiatry 194:298-305. 2009
  6. ncbi request reprint "Lesionnaire's syndrome"
    Dennis Velakoulis
    Melbourne Neuropsychiatry Centre, Royal Melbourne Hospital, Grattan Street, Parkville, VIC 3050, Australia
    Med J Aust 183:679. 2005
  7. doi request reprint Progressive gray matter reduction of the superior temporal gyrus during transition to psychosis
    Tsutomu Takahashi
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne and Melbourne Health, Australia
    Arch Gen Psychiatry 66:366-76. 2009
  8. doi request reprint Saccades in adult Niemann-Pick disease type C reflect frontal, brainstem, and biochemical deficits
    L A Abel
    Department of Optometry and Vision Sciences, University of Melbourne, Parkville, Australia
    Neurology 72:1083-6. 2009
  9. ncbi request reprint Proton magnetic resonance spectroscopy in first episode psychosis and ultra high-risk individuals
    Stephen J Wood
    Melbourne Neuropsychiatry Centre, University of Melbourne and Sunshine Hospital, Melbourne, Australia
    Schizophr Bull 29:831-43. 2003
  10. pmc Brain surface contraction mapped in first-episode schizophrenia: a longitudinal magnetic resonance imaging study
    D Sun
    Department of Psychiatry, Melbourne Neuropsychiatry Centre, University of Melbourne and Melbourne Health, Parkville, Vic, Australia
    Mol Psychiatry 14:976-86. 2009

Detail Information

Publications110 found, 100 shown here

  1. doi request reprint Hippocampal pathology in individuals at ultra-high risk for psychosis: a multi-modal magnetic resonance study
    Stephen J Wood
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne and Melbourne Health, Parkville, Vic, Australia
    Neuroimage 52:62-8. 2010
    ..However, standard measures of neuroanatomical disturbance do not appear to be predictive of later transition, and instead are likely to be non-specific and common in cases that later develop a non-psychotic disorder...
  2. ncbi request reprint Conn's dementia
    Dennis Velakoulis
    Neuropsychiatry Unit, Royal Melbourne Hospital, Parkville, Vic, Australia
    Lancet Neurol 1:131. 2002
  3. ncbi request reprint Hippocampal and amygdala volumes according to psychosis stage and diagnosis: a magnetic resonance imaging study of chronic schizophrenia, first-episode psychosis, and ultra-high-risk individuals
    Dennis Velakoulis
    Melbourne Neuropsychiatry Centre and Department of Psychiatry, University of Melbourne, Australia
    Arch Gen Psychiatry 63:139-49. 2006
    ..These studies have been limited by small samples and the absence of patients early in the course of illness...
  4. doi request reprint Abnormal hippocampal distribution of TDP-43 in patients with-late onset psychosis
    Dennis Velakoulis
    Neuropsychiatry Unit, Royal Melbourne Hospital, Vic, Australia
    Aust N Z J Psychiatry 43:739-45. 2009
    ..A secondary objective was to identify clinicopathological relationships of any such abnormalities...
  5. doi request reprint Frontotemporal dementia presenting as schizophrenia-like psychosis in young people: clinicopathological series and review of cases
    D Velakoulis
    Neuropsychiatry Unit, Level 2 John Cade Building, Royal Melbourne Hospital, Parkville, Victoria 3052, Australia
    Br J Psychiatry 194:298-305. 2009
    ..Few studies have investigated the relationship between schizophrenia and frontotemporal dementia...
  6. ncbi request reprint "Lesionnaire's syndrome"
    Dennis Velakoulis
    Melbourne Neuropsychiatry Centre, Royal Melbourne Hospital, Grattan Street, Parkville, VIC 3050, Australia
    Med J Aust 183:679. 2005
  7. doi request reprint Progressive gray matter reduction of the superior temporal gyrus during transition to psychosis
    Tsutomu Takahashi
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne and Melbourne Health, Australia
    Arch Gen Psychiatry 66:366-76. 2009
    ..It is unknown whether these progressive processes predate the onset of psychosis...
  8. doi request reprint Saccades in adult Niemann-Pick disease type C reflect frontal, brainstem, and biochemical deficits
    L A Abel
    Department of Optometry and Vision Sciences, University of Melbourne, Parkville, Australia
    Neurology 72:1083-6. 2009
    ..No study has examined the frontally driven volitional control of saccadic eye movements in NPC...
  9. ncbi request reprint Proton magnetic resonance spectroscopy in first episode psychosis and ultra high-risk individuals
    Stephen J Wood
    Melbourne Neuropsychiatry Centre, University of Melbourne and Sunshine Hospital, Melbourne, Australia
    Schizophr Bull 29:831-43. 2003
    ..This finding did not discriminate between those UHR individuals who later became psychotic and those who did not...
  10. pmc Brain surface contraction mapped in first-episode schizophrenia: a longitudinal magnetic resonance imaging study
    D Sun
    Department of Psychiatry, Melbourne Neuropsychiatry Centre, University of Melbourne and Melbourne Health, Parkville, Vic, Australia
    Mol Psychiatry 14:976-86. 2009
    ....
  11. ncbi request reprint Stability of olfactory identification deficits in neuroleptic-naive patients with first-episode psychosis
    W J Brewer
    Cognitive Neuropsychiatry Research, University of Melbourne, Parkville, Melbourne, Australia
    Am J Psychiatry 158:107-15. 2001
    ..Olfactory identification deficits and their relationship to negative symptoms in patients with schizophrenia were examined in patients with recent-onset psychosis, the majority of whom were neuroleptic naive...
  12. doi request reprint Subcortical volumetric reductions in adult Niemann-Pick disease type C: a cross-sectional study
    M Walterfang
    Melbourne Neuropsychiatry Centre, University of Melbourne, Melbourne, Australia
    AJNR Am J Neuroradiol 34:1334-40. 2013
    ..We sought to examine a range of deep gray matter structures in adults with NPC and relate these to clinical variables...
  13. ncbi request reprint In vivo evidence for early neurodevelopmental anomaly of the anterior cingulate cortex in bipolar disorder
    A Fornito
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne, Melbourne, Vic, Australia
    Acta Psychiatr Scand 116:467-72. 2007
    ..We investigated the evidence for early neurodevelopmental anomalies in the ACC and adjacent paracingulate cortex (PaC) of BD patients by studying cortical folding patterns of the region...
  14. doi request reprint Superior temporal gyrus volume in antipsychotic-naive people at risk of psychosis
    Tsutomu Takahashi
    Melbourne Neuropsychiatry Centre, c o National Neuroscience Facility, 161 Barry Street, Carlton South, Victoria 3053, Australia
    Br J Psychiatry 196:206-11. 2010
    ..Morphological abnormalities of the superior temporal gyrus have been consistently reported in schizophrenia, but the timing of their occurrence remains unclear...
  15. doi request reprint Gender dimorphism in siblings with schizophrenia-like psychosis due to Niemann-Pick disease type C
    M Walterfang
    Neuropsychiatry Unit, Royal Melbourne Hospital, Royal Melbourne Hospital 3050, Melbourne, Victoria, Australia
    J Inherit Metab Dis 32:S221-6. 2009
    ..Their illness onset, course and response to treatment mirrors the sex dimorphism seen in schizophrenia, and is suggestive of an interaction between the neurobiology of their metabolic disorder and sex differences in neurodevelopment...
  16. ncbi request reprint Anterior cingulate activation in antipsychotic-naïve first-episode schizophrenia
    M Yucel
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne, Melbourne, Carlton South, VIC 3053, Australia
    Acta Psychiatr Scand 115:155-8. 2007
    ..Anterior cingulate (ACC) hypo-activity is commonly observed in chronically ill schizophrenia patients. However, it is unclear whether this is secondary to persistent illness and/or medication...
  17. doi request reprint Pontine-to-midbrain ratio indexes ocular-motor function and illness stage in adult Niemann-Pick disease type C
    M Walterfang
    Melbourne Neuropsychiatry Centre, University of Melbourne, Melbourne
    Eur J Neurol 19:462-7. 2012
    ..Our aim was to utilize a method for brainstem atrophy, validated in progressive supranuclear palsy (PSP), in a group of adult patients with NPC, and explore its relationship to illness variables and ocular-motor functioning...
  18. ncbi request reprint Neuroimaging and emerging psychotic disorders: the Melbourne ultra-high risk studies
    C Pantelis
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne, Royal Melbourne Hospital, Sunshine Hospital, 176 Furlong Road, St Albans, Victoria 3021, Australia
    Int Rev Psychiatry 19:371-81. 2007
    ..Further, active changes during transition to illness may present the potential to intervene and ameliorate these changes with potential benefit clinically...
  19. doi request reprint Insular cortex gray matter changes in individuals at ultra-high-risk of developing psychosis
    Tsutomu Takahashi
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne and Melbourne Health, Victoria, Australia
    Schizophr Res 111:94-102. 2009
    ..Whether these longitudinal changes are features of the disorder or related to treatment with antipsychotic medication remains to be determined...
  20. doi request reprint Follow-up MRI study of the insular cortex in first-episode psychosis and chronic schizophrenia
    Tsutomu Takahashi
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne and Melbourne Health, Victoria, Australia
    Schizophr Res 108:49-56. 2009
    ....
  21. ncbi request reprint The development and validation of a carer questionnaire to assess cognitive function in neuropsychiatric patients
    Sharan Randhawa
    Neuropsychiatry Unit, Royal Melbourne Hospital, and Melbourne Neuropsychiatry Centre, University of Melbourne, Australia
    J Psychosom Res 63:93-8. 2007
    ....
  22. pmc Effects of NRG1 and DAOA genetic variation on transition to psychosis in individuals at ultra-high risk for psychosis
    C A Bousman
    Melbourne Brain Centre, Department of Psychiatry, The University of Melbourne, Parkville, Vic, Australia
    Transl Psychiatry 3:e251. 2013
    ..None of the assessed DAOA htSNPs were associated with transition. Our findings suggest NRG1 genetic variation may improve our ability to identify UHR individuals at risk for transition to psychosis...
  23. ncbi request reprint Reduced volume of parietal and frontal association areas in patients with schizophrenia characterized by passivity delusions
    P Maruff
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Sunshine Hospital, St Albans, Melbourne, Australia
    Psychol Med 35:783-9. 2005
    ..Neuropsychological and functional neuroimaging data suggest that passivity delusions are associated with dysfunction of the parietal lobe association cortex...
  24. doi request reprint Size and shape of the corpus callosum in adult Niemann-Pick type C reflects state and trait illness variables
    M Walterfang
    Melbourne Neuropsychiatry Centre, University of Melbourne, Melbourne, Australia
    AJNR Am J Neuroradiol 32:1340-6. 2011
    ..This study sought to examine the structure of the callosum in a group of adult patients with NPC and compared callosal structure with a group of matched controls, and to relate callosal structure with state and trait illness variables...
  25. doi request reprint White and gray matter alterations in adults with Niemann-Pick disease type C: a cross-sectional study
    M Walterfang
    Melbourne Neuropsychiatry Centre and Department of Psychiatry, University of Melbourne and North Western Mental Health Program, Sunshine Hospital and Royal Melbourne Hospital, Melbourne, Australia
    Neurology 75:49-56. 2010
    ..Our aim was to investigate a well-characterized sample of adults with confirmed NPC for gray and white matter abnormalities...
  26. ncbi request reprint Dysfunction of dorsolateral prefrontal cortex in antipsychotic-naïve schizophreniform psychosis
    Ben J Harrison
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne, Australia
    Psychiatry Res 148:23-31. 2006
    ....
  27. doi request reprint Prevalence of large cavum septi pellucidi in ultra high-risk individuals and patients with psychotic disorders
    Tsutomu Takahashi
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne and Melbourne Health, Victoria, Australia
    Schizophr Res 105:236-44. 2008
    ..These findings suggest that the CSP is not a neurodevelopmental marker of psychosis and cast doubt over the notion that it plays a major role in the neurobiology of psychosis...
  28. ncbi request reprint Anterior cingulate activation during Stroop task performance: a PET to MRI coregistration study of individual patients with schizophrenia
    Murat Yucel
    Cognitive Neuropsychiatry Research and Academic Unit, Department of Psychiatry, Howard Florey Institute, University of Melbourne, Victoria, Australia
    Am J Psychiatry 159:251-4. 2002
    ....
  29. ncbi request reprint Magnetic resonance spectroscopy and schizophrenia: what have we learnt?
    A L Vance
    Cognitive Neuropsychiatry Unit, Mental Health Research Institute of Victoria, Parkville, Australia
    Aust N Z J Psychiatry 34:14-25. 2000
    ..We review the literature and discuss the theoretical constructs that form the presumed impetus for these studies in light of the current methodological limitations. Future directions are noted...
  30. doi request reprint A 1H-MRS investigation of the medial temporal lobe in antipsychotic-naïve and early-treated first episode psychosis
    Stephen J Wood
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne and Melbourne Health, Australia
    Schizophr Res 102:163-70. 2008
    ..Seemingly illness-related Cr/PCr elevations were also specific to the diagnosis of schizophrenia-spectrum disorder and seem worthy of future study...
  31. doi request reprint An MRI study of the superior temporal subregions in first-episode patients with various psychotic disorders
    Tsutomu Takahashi
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne and Melbourne Health, Victoria, Australia
    Schizophr Res 113:158-66. 2009
    ..Our findings indicate that morphologic abnormalities of the STG gray matter are specific to schizophrenia among various psychotic disorders, implicating its role in the underlying pathophysiology of schizophrenia...
  32. doi request reprint Caudate nucleus volume in individuals at ultra-high risk of psychosis: a cross-sectional magnetic resonance imaging study
    Katrina L Hannan
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Parkville, Victoria, Australia
    Psychiatry Res 182:223-30. 2010
    ..Future research should examine changes longitudinally together with analysis of shape to assess subregions of the caudate that connect with prefrontal cortex...
  33. ncbi request reprint Prediction of functional outcome 18 months after a first psychotic episode: a proton magnetic resonance spectroscopy study
    Stephen J Wood
    Melbourne Neuropsychiatry Centre, University of Melbourne, c o National Neuroscience Facility, 161 Barry Street, Carlton, Melbourne, Victoria 3053, Australia
    Arch Gen Psychiatry 63:969-76. 2006
    ..These studies have generally been negative, perhaps because gray and white matter volumes inaccurately assess the underlying dysfunction that might be predictive of outcome...
  34. ncbi request reprint Surface-based morphometry of the anterior cingulate cortex in first episode schizophrenia
    Alex Fornito
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Australia
    Hum Brain Mapp 29:478-89. 2008
    ....
  35. ncbi request reprint Impairments of response conflict monitoring and resolution in schizophrenia
    M Yucel
    Cognitive Neuropsychiatry Research and Academic Unit, Mental Health Research Institute of Victoria, Parkville, Australia
    Psychol Med 32:1251-60. 2002
    ..However, this hypothesis is based on performance on paradigms that require overt or covert shifts of spatial attention...
  36. ncbi request reprint Neurobiological findings in early phase schizophrenia
    D Copolov
    The Mental Health Research Institute of Victoria, 155 Oak St, Parkville, Victoria, Australia
    Brain Res Brain Res Rev 31:157-65. 2000
    ..Although there is a growing literature on first episode psychosis, there is a striking dearth of information on the neurobiology of the prodrome...
  37. ncbi request reprint Visuospatial memory and learning in first-episode schizophreniform psychosis and established schizophrenia: a functional correlate of hippocampal pathology?
    S J Wood
    Cognitive Neuropsychiatry Research and Academic Unit, University of Melbourne, Sunshine Hospital, St Albans, Victoria, Australia
    Psychol Med 32:429-38. 2002
    ..Given the reported findings of reduced hippocampal volume in schizophrenia, we used a theoretically sensitive test of the right medial temporal lobe to determine the nature of the visuospatial memory deficit in the disorder...
  38. ncbi request reprint Incidental radiological findings on brain magnetic resonance imaging in first-episode psychosis and chronic schizophrenia
    D I Lubman
    Cognitive Neuropsychiatry Research and Academic Unit, The University of Melbourne and Sunshine Hospital, Melbourne, Australia
    Acta Psychiatr Scand 106:331-6. 2002
    ..To investigate whether patients with first-episode psychosis or chronic schizophrenia have an increased incidence of magnetic resonance imaging (MRI) brain abnormalities compared with control subjects...
  39. doi request reprint Corpus callosum morphology and relationship to orbitofrontal and lateral ventricular volume in teenagers with first-presentation borderline personality disorder
    Mark Walterfang
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Melbourne, Australia
    Psychiatry Res 183:30-7. 2010
    ..We predicted that a first-presentation BPD cohort who demonstrated orbitofrontal cortex (OFC) reductions would show regional reductions in the anterior corpus callosum...
  40. doi request reprint Corpus callosum size and shape in established bipolar affective disorder
    Mark Walterfang
    Melbourne Neuropsychiatry Centre, University of Melbourne, Melbourne, Victoria 3050, Australia
    Aust N Z J Psychiatry 43:838-45. 2009
    ..The aim of the present study was therefore to examine callosal size and shape in a well-defined group of bipolar affective disorder patients and controls...
  41. ncbi request reprint Functional and biochemical alterations of the medial frontal cortex in obsessive-compulsive disorder
    Murat Yucel
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Victoria 3053, Australia
    Arch Gen Psychiatry 64:946-55. 2007
    ..However, the precise regions and the neural alterations associated with this abnormality remain unclear...
  42. ncbi request reprint The neuropsychiatry of adrenomyeloneuropathy
    Mark A Walterfang
    Neuropsychiatry Unit, Royal Melbourne Hospital, Melbourne, Australia
    CNS Spectr 12:696-701. 2007
    ..Given that cerebral involvement occurs in up to half of AMN sufferers, we hypothesized that rates of mental illness may match those with adult ALD...
  43. doi request reprint Corpus callosum shape alterations in individuals prior to the onset of psychosis
    Mark Walterfang
    Melbourne Neuropsychiatry Centre and Department of Psychiatry, University of Melbourne, North Western Mental Health Program, Sunshine Hospital, Melbourne, Australia
    Schizophr Res 103:1-10. 2008
    ..These changes may reflect primary pathology of orbitofrontal and medial frontal cortex, or deficits in anterior interhemispheric myelination...
  44. ncbi request reprint Adolescent obsessive compulsive disorder heralding chorea-acanthocytosis
    Mark Walterfang
    Melbourne Neuropsychiatry Centre, University of Melbourne, Melbourne, Australia
    Mov Disord 23:422-5. 2008
    ....
  45. pmc Progressive changes in the development toward schizophrenia: studies in subjects at increased symptomatic risk
    Stephen J Wood
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne, Australia
    Schizophr Bull 34:322-9. 2008
    ..Active changes during transition to illness may present the potential to intervene and ameliorate these changes with potential benefit clinically...
  46. doi request reprint Morphology of the corpus callosum at different stages of schizophrenia: cross-sectional study in first-episode and chronic illness
    Mark Walterfang
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne North Western Mental Health Program, Sunshine Hospital, Royal Melbourne Hospital, Melbourne corrected
    Br J Psychiatry 192:429-34. 2008
    ..The shape of the corpus callosum may differ in schizophrenia, although no study has compared first-episode with established illness...
  47. doi request reprint Neuropsychiatric morbidity in focal epilepsy
    Sophia J Adams
    Melbourne Neuropsychiatry Centre, The University of Melbourne and Royal Melbourne Hospital, Level 2, John Cade Building, Melbourne, Australia
    Br J Psychiatry 192:464-9. 2008
    ..Many studies were undertaken before the advent of video electroencephalogram monitoring (VEM) and magnetic resonance imaging (MRI)...
  48. doi request reprint White matter volume changes in people who develop psychosis
    Mark Walterfang
    Melbourne Neuropsychiatry Centre, Level 2, Royal Melbourne Hospital, 3050 Australia
    Br J Psychiatry 193:210-5. 2008
    ..Grey matter changes have been described in individuals who are pre- and peri-psychotic, but it is unclear if these changes are accompanied by changes in white matter structures...
  49. doi request reprint Corpus callosum size and shape in individuals with current and past depression
    Mark Walterfang
    Neuropsychiatry Unit, Level 2, John Cade Building, Royal Melbourne Hospital 3050 Australia
    J Affect Disord 115:411-20. 2009
    ..The corpus callosum enables the efficient linking of the two cerebral hemispheres. Reductions in the size of the anterior callosum have been described in geriatric depression, although findings in young adults have been much more equivocal...
  50. ncbi request reprint Increased prefrontal cerebral blood flow in first-episode schizophrenia following treatment: longitudinal positron emission tomography study
    Warrick J Brewer
    ORYGEN Research Centre, Locked Bag 10, Parkville, VIC 3052, Australia and Early Psychosis Prevention and Intervention Centre, Department of Psychiatry, University of Melbourne, Melbourne, Victoria, Australia
    Aust N Z J Psychiatry 41:129-35. 2007
    ..The objective of the current study was to investigate executive-control related neural activity from first onset of the illness through to symptom stabilization...
  51. ncbi request reprint Moyamoya disease in a patient with schizophrenia
    Dan I Lubman
    Cognitive Neuropsychiatry Research and Academic Unit, University of Melbourne and Sunshine Hospital, Victoria, Australia
    J Int Neuropsychol Soc 9:806-10. 2003
    ..We discuss the nature of possible interactions between the 2 conditions. This case also highlights the importance of re-evaluating patients with atypical or treatment-resistant psychoses for cerebral pathology...
  52. doi request reprint Superior temporal gyrus volume in teenagers with first-presentation borderline personality disorder
    Tsutomu Takahashi
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Melbourne, Australia
    Psychiatry Res 182:73-6. 2010
    ..Our preliminary findings might reflect the neurobiological heterogeneity of the disorder...
  53. doi request reprint Anatomic abnormalities of the anterior cingulate cortex before psychosis onset: an MRI study of ultra-high-risk individuals
    Alex Fornito
    Department of Psychiatry, Melbourne Neuropsychiatry Centre, University of Melbourne, Carlton South, Victoria, Australia
    Biol Psychiatry 64:758-65. 2008
    ..In this study, we characterized prepsychotic ACC abnormalities in a sample of individuals at ultra-high-risk (UHR) for psychosis...
  54. ncbi request reprint Diseases of white matter and schizophrenia-like psychosis
    Mark Walterfang
    Melbourne Neuropsychiatry Centre, Level 2, John Cade Building, Royal Melbourne Hospital, Melbourne, Victoria 3050, Australia
    Aust N Z J Psychiatry 39:746-56. 2005
    ..To analyse the available data regarding the presentation of psychosis in diseases of central nervous system (CNS) white matter...
  55. doi request reprint Grey and white matter abnormalities are associated with impaired spatial working memory ability in first-episode schizophrenia
    Luca Cocchi
    Department of Psychiatry, Melbourne Neuropsychiatry Centre, The University of Melbourne and Melbourne Health, Melbourne, Australia
    Schizophr Res 115:163-72. 2009
    ....
  56. doi request reprint Corpus callosum size and shape alterations in individuals with bipolar disorder and their first-degree relatives
    Mark Walterfang
    Melbourne Neuropsychiatry Centre, University of Melbourne and Melbourne Health, Melbourne, Australia
    Prog Neuropsychopharmacol Biol Psychiatry 33:1050-7. 2009
    ..Global and regional thinning of the callosum is seen in BD but not in their first-degree relatives. This suggests that CC abnormalities are linked to disease expression in BD and may not represent a marker of familial predisposition...
  57. ncbi request reprint Neuropathological, neurogenetic and neuroimaging evidence for white matter pathology in schizophrenia
    Mark Walterfang
    Melbourne Neuropsychiatry Centre, University of Melbourne, Victoria, Australia
    Neurosci Biobehav Rev 30:918-48. 2006
    ....
  58. ncbi request reprint Is schizophrenia associated with narcolepsy?
    Mark Walterfang
    Neuropsychiatry Unit, Royal Melbourne Hospital, Parkville, Victoria, Australia
    Cogn Behav Neurol 18:113-8. 2005
    ..To determine the nature of the relationship between schizophrenia-like psychosis and narcolepsy...
  59. ncbi request reprint The neuropsychiatry of Niemann-Pick type C disease in adulthood
    Mark Walterfang
    Neuropsychiatry Unit, Level 2, John Cade Building, Royal Melbourne Hospital, Melbourne 3050, Australia
    J Neuropsychiatry Clin Neurosci 18:158-70. 2006
    ....
  60. doi request reprint The effect of atypical antipsychotics on pituitary gland volume in patients with first-episode psychosis: a longitudinal MRI study
    John Paul Nicolo
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne and Melbourne Health, Australia
    Schizophr Res 116:49-54. 2010
    ..Qualifying and quantifying the effect of atypical antipsychotics on the volume of the pituitary gland will determine whether this measure is valid as a future estimate of HPA-axis activation in psychotic populations...
  61. ncbi request reprint Cortical release signs in psychiatry
    Mark Walterfang
    Neuropsychiatry Centre, University of Melbourne, Melbourne, Australia
    Aust N Z J Psychiatry 39:317-27. 2005
    ..To review the role of cortical release signs (CRS) in neuropsychiatry...
  62. doi request reprint Corpus callosum size and shape in first-episode affective and schizophrenia-spectrum psychosis
    Mark Walterfang
    Melbourne Neuropsychiatry Centre, University of Melbourne, Melbourne, Australia
    Psychiatry Res 173:77-82. 2009
    ..This suggests that schizoaffective disorder may represent two interacting illness processes or be mid-way along a continuum of these two broad categories of illness at first psychosis...
  63. doi request reprint Anterior cingulate cortex abnormalities associated with a first psychotic episode in bipolar disorder
    Alex Fornito
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, School of Behavioural Science, University of Melbourne, National Neuroscience Facility, 161 Barry Street, Carlton South, VIC 3053, Australia
    Br J Psychiatry 194:426-33. 2009
    ....
  64. ncbi request reprint The NUCOG: validity and reliability of a brief cognitive screening tool in neuropsychiatric patients
    Mark Walterfang
    Neuropsychiatry Unit, Royal Melbourne Hospital, Parkville, Victoria, Australia
    Aust N Z J Psychiatry 40:995-1002. 2006
    ....
  65. ncbi request reprint Epilepsy, progessive movement disorder and cognitive decline
    B Robertson
    Neuropsychiatry Unit, Melbourne Neuropsychiatry Centre, University of Melbourne and North Western Mental Health, Royal Melbourne Hospital, Parkville, Melbourne, Victoria 3052, Australia
    J Clin Neurosci 15:812. 2008
  66. pmc Progressive brain structural changes mapped as psychosis develops in 'at risk' individuals
    Daqiang Sun
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Parkville, Victoria, Australia
    Schizophr Res 108:85-92. 2009
    ..We hypothesized that progressive volume loss occurs in prefrontal regions during the transition to psychosis...
  67. doi request reprint Insular cortex volume and impulsivity in teenagers with first-presentation borderline personality disorder
    Tsutomu Takahashi
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Melbourne, Australia
    Prog Neuropsychopharmacol Biol Psychiatry 33:1395-400. 2009
    ..Further studies are needed to clarify whether the potential relationship between the insular cortex volume and impulsivity is specific to BPD...
  68. doi request reprint Adhesio interthalamica in individuals at high-risk for developing psychosis and patients with psychotic disorders
    Tsutomu Takahashi
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne and Melbourne Health, Victoria, Australia
    Prog Neuropsychopharmacol Biol Psychiatry 32:1708-14. 2008
    ....
  69. ncbi request reprint A manual and automated MRI study of anterior cingulate and orbito-frontal cortices, and caudate nucleus in obsessive-compulsive disorder: comparison with healthy controls and patients with schizophrenia
    Jem Riffkin
    Melbourne Neuropsychiatry Centre, University of Melbourne and Sunshine Hospital, Melbourne, Victoria, Australia
    Psychiatry Res 138:99-113. 2005
    ..The findings suggest that in contrast to findings in SCZ, there are very few (if any) gross structural anomalies in OCD...
  70. ncbi request reprint Non-reduction in hippocampal volume is associated with higher risk of psychosis
    Lisa J Phillips
    PACE Clinic, Department of Psychiatry, University of Melbourne, 35 Poplar Road, Victoria 3052, Parkville, Australia
    Schizophr Res 58:145-58. 2002
    ..Alternatively, selection factors associated with the UHR cohort may have created a bias in the results. Replication of these results is required in other high-risk cohorts...
  71. doi request reprint Diagnostic specificity of the insular cortex abnormalities in first-episode psychotic disorders
    Tsutomu Takahashi
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne and Melbourne Health, Victoria, Australia
    Prog Neuropsychopharmacol Biol Psychiatry 33:651-7. 2009
    ..These findings suggest that the widespread volume reduction of the insular cortex is specific to established schizophrenia, implicating its role in the neurobiology of clinical characteristics associated with schizophrenia...
  72. ncbi request reprint Morphology of the paracingulate sulcus and executive cognition in schizophrenia
    Alex Fornito
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne, National Neuroscience Facility, Levels 2 and 3, Alan Gilbert Building, 161 Barry St, Carlton South, Victoria 3053, Australia
    Schizophr Res 88:192-7. 2006
    ..This suggests that prior reports of impaired performance on such tasks in schizophrenia may be partly explained by the reduced frequency of a leftward PCS asymmetry in this population...
  73. ncbi request reprint Validity and reliability of the Behavioural Assessment Tool for Cognition and Higher Function (BATCH) in neuropsychiatric patients
    Kathryn Miller
    Neuropsychiatry Unit, Level 2, John Cade Building, Royal Melbourne Hospital, Parkville, Vic, Australia
    Aust N Z J Psychiatry 41:697-704. 2007
    ..Its capacity to provide a measure of cognitive function through observational means was assessed in a neuropsychiatric unit...
  74. doi request reprint Attentional set-shifting ability in first-episode and established schizophrenia: Relationship to working memory
    Christos Pantelis
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Sunshine Hospital, St Albans, Victoria 3021, Australia
    Schizophr Res 112:104-13. 2009
    ..Longitudinal studies assessing these cognitive functions from illness onset or in prepsychotic individuals are required...
  75. ncbi request reprint Fractionation of verbal memory impairment in schizophrenia and schizophreniform psychosis
    Stephen J Wood
    Melbourne Neuropsychiatry Centre, c National Neuroscience Facility, Carlton, Melbourne, Victoria, Australia
    Aust N Z J Psychiatry 41:732-9. 2007
    ..The impact of antipsychotic medications is also unclear. The purpose of the present paper was to investigate verbal memory performance in established schizophrenia (SZ) and first-episode schizophreniform psychosis (FE)...
  76. doi request reprint Pituitary volume in patients with bipolar disorder and their first-degree relatives
    Tsutomu Takahashi
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne and Melbourne Health, Victoria, Australia
    J Affect Disord 124:256-61. 2010
    ..In addition, the contribution of genetic factors to the pituitary changes in BD remains largely unknown...
  77. ncbi request reprint Pituitary volume predicts future transition to psychosis in individuals at ultra-high risk of developing psychosis
    Belinda Garner
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne, Royal Melbourne Hospital, Melbourne, Australia
    Biol Psychiatry 58:417-23. 2005
    ..We examined pituitary volume before the onset of psychosis in subjects who were at ultra-high risk (UHR) for developing psychosis...
  78. ncbi request reprint Reversible dementia with psychosis: Hashimoto's encephalopathy
    Ramon Mocellin
    Neuropsychiatry Unit, Melbourne Neuropsychiatry Center, Royal Melbourne Hospital, Melbourne, Austrailia
    Psychiatry Clin Neurosci 60:761-3. 2006
    ..Primarily a diagnosis of exclusion, HE should be considered in cases of encephalopathy in which standard investigations are negative...
  79. ncbi request reprint Images in neuroscience: psychosis and vertical supranuclear opthalmoplegia
    M Walterfang
    Neuropsychiatry Unit, Level 2, John Cade Building, Royal Melbourne Hospital, Parkville, Victoria 3052, Australia
    J Clin Neurosci 15:291, 370-1. 2008
  80. ncbi request reprint The influence of sulcal variability on morphometry of the human anterior cingulate and paracingulate cortex
    Alex Fornito
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne, Australia
    Neuroimage 33:843-54. 2006
    ....
  81. ncbi request reprint Variability of the paracingulate sulcus and morphometry of the medial frontal cortex: associations with cortical thickness, surface area, volume, and sulcal depth
    Alex Fornito
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne, Melbourne, Australia
    Hum Brain Mapp 29:222-36. 2008
    ....
  82. ncbi request reprint Weight loss, falls, and neuropsychiatric symptoms in a 56 year-old man
    Ramon Mocellin
    Neuropsychiatry Unit, Royal Melbourne Hospital, Melbourne, Australia
    Lancet Neurol 4:381-8. 2005
  83. doi request reprint Increased pituitary volume in schizophrenia spectrum disorders
    Tsutomu Takahashi
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne and Melbourne Health, Victoria 3053, Australia
    Schizophr Res 108:114-21. 2009
    ....
  84. ncbi request reprint Thalamic and caudate volumes in monozygotic twins discordantfor schizophrenia
    Nicola Bridle
    Cognitive Neuropsychiatry Research and Academic Unit, The University of Melbourne, Parkville, Victoria, Australia
    Aust N Z J Psychiatry 36:347-54. 2002
    ..Previous studies have been inconsistent in identifying structural and functional abnormalities in these structures. However, methodologies in these studies have been unreliable and some have not adequately matched patients and controls...
  85. ncbi request reprint Individual differences in anterior cingulate/paracingulate morphology are related to executive functions in healthy males
    Alexander Fornito
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne, Sunshine Hospital, 176 Furlong Road, St Albans, Victoria 3021, Australia
    Cereb Cortex 14:424-31. 2004
    ..It therefore appears that normal variations in brain morphology are associated with individual differences in cognitive abilities...
  86. ncbi request reprint Impairment of olfactory identification ability in individuals at ultra-high risk for psychosis who later develop schizophrenia
    Warrick J Brewer
    Department of Psychiatry, University of Melbourne, Melbourne, Australia
    Am J Psychiatry 160:1790-4. 2003
    ..Previous investigation has revealed stable olfactory identification deficits in neuroleptic-naive patients experiencing a first episode of psychosis, but it is unknown if these deficits predate illness onset...
  87. ncbi request reprint Hippocampal and anterior cingulate morphology in subjects at ultra-high-risk for psychosis: the role of family history of psychotic illness
    Stephen J Wood
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne, National Neuroscience Facility, 161 Barry Street, Carlton South VIC 3053, Australia
    Schizophr Res 75:295-301. 2005
    ..Some appear to predate the illness and may be genetic in origin, while others are associated with the onset of the disorder...
  88. ncbi request reprint Increased pituitary volume in antipsychotic-free and antipsychotic-treated patients of the AEsop first-onset psychosis study
    Carmine M Pariante
    Stress, Psychiatry and Immunology Laboratory, Division of Psychological Medicine, Clinical Neuropharmacology PO51, Institute of Psychiatry, King s College London, 1 Windsor Walk, Denmark Hill, London SE5 8AF, UK
    Neuropsychopharmacology 30:1923-31. 2005
    ..This activation of the hormonal stress response could participate to the important metabolic abnormalities observed in patients with psychosis...
  89. ncbi request reprint Early and late neurodevelopmental disturbances in schizophrenia and their functional consequences
    Christos Pantelis
    Cognitive Neuropsychiatry Research and Academic Unit, Sunshine Hospital, 176 Furlong Road, St Albans, 3021, Victoria, Australia
    Aust N Z J Psychiatry 37:399-406. 2003
    ..In this paper we review the timing of structural changes in schizophrenia and argue that schizophrenia is a neuro-developmental disorder with limited progressive brain changes occurring during the evolution and early phase of psychosis...
  90. ncbi request reprint Neuroanatomical abnormalities before and after onset of psychosis: a cross-sectional and longitudinal MRI comparison
    Christos Pantelis
    Cognitive Neuropsychiatry Research and Academic Unit, and Melbourne Neuropsychiatry Centre, Mental Health Programme, Department of Psychiatry, University of Melbourne and Sunshine Hospital, Victoria, Melbourne, Australia
    Lancet 361:281-8. 2003
    ..We investigated this issue with MRI to study people with prodromal symptoms who are at ultra high-risk for the development of psychosis...
  91. ncbi request reprint A case of schizophrenia with complete agenesis of the corpus callosum
    Dhamodharan Chinnasamy
    Logan Hospital, Mental Health Division, Loganholme, Queensland, Australia
    Australas Psychiatry 14:327-30. 2006
    ..To describe the case of a person with schizophrenia and agenesis of the corpus callosum...
  92. ncbi request reprint Increased duration of illness is associated with reduced volume in right medial temporal/anterior cingulate grey matter in patients with chronic schizophrenia
    Dennis Velakoulis
    Cognitive Neuropsychiatry Research and Academic Unit, Department of Psychiatry, University of Melbourne and Sunshine Hospital, St Albans, Australia
    Schizophr Res 57:43-9. 2002
    ..The inverse correlation between right frontal, temporal and cerebellar volumes and the time since the onset of schizophrenia could reflect progressive tissue loss following the first episode of the disorder...
  93. ncbi request reprint Recovery of cognitive function in neuropsychiatric Langerhan's cell histiocytosis
    Philip Ryan
    Neuropsychiatry Unit, Melbourne Neuropsychiatry Center, Royal Melbourne Hospital, Melbourne, Australia
    Psychiatry Clin Neurosci 60:629-32. 2006
    ..This differential recovery of motor and cognitive functioning may relate to the interaction between LCH and childhood and adolescent neurodevelopmental processes...
  94. ncbi request reprint Bipolar disorder and Niemann-Pick disease type C
    Danny Sullivan
    Am J Psychiatry 162:1021-2. 2005
  95. doi request reprint Orbitofrontal, amygdala and hippocampal volumes in teenagers with first-presentation borderline personality disorder
    Andrew M Chanen
    ORYGEN Research Centre, Department of Psychiatry, The University of Melbourne, Melbourne, Australia
    Psychiatry Res 163:116-25. 2008
    ..Hippocampal and amygdala volume reductions observed in adult BPD samples might develop during the course of the disorder, although longitudinal studies are needed to examine this...
  96. ncbi request reprint Pituitary volume in psychosis
    Carmine M Pariante
    Division of Psychological Medicine, Institute of Psychiatry, King s College London, UK
    Br J Psychiatry 185:5-10. 2004
    ..Patients with psychosis have activation of the hypothalamic-pituitary-adrenal (HPA) axis during the acute phase of the psychosis. Whether this has any morphological consequences for the pituitary gland is currently unknown...
  97. ncbi request reprint Morphology of the anterior cingulate cortex in young men at ultra-high risk of developing a psychotic illness
    Murat Yucel
    Department of Psychiatry, University of Melbourne, Parkville, Victoria, Australia
    Br J Psychiatry 182:518-24. 2003
    ..The anterior cingulate cortex (ACC) is consistently implicated in the pathophysiology of schizophrenia, and our own work has identified morphological anomalies in the ACC of people with this disorder...
  98. ncbi request reprint Paracingulate morphologic differences in males with established schizophrenia: a magnetic resonance imaging morphometric study
    Murat Yucel
    Cognitive Neuropsychiatry Research and Academic Unit, Department of Psychiatry, The University of Melbourne, Sunshine Hospital, Melbourne, Victoria, Australia
    Biol Psychiatry 52:15-23. 2002
    ..Given the evidence showing an absence or reversal of normal anatomical asymmetries in patients with schizophrenia, the current study examined the anterior cingulate cortex sulcal-gyral patterns in patients with schizophrenia...
  99. pmc Anterior cingulate dysfunction: implications for psychiatric disorders?
    Murat Yucel
    Melbourne Neuropsychiatry Centre Sunshine Hospital, Department of Psychiatry, University of Melbourne, Parkville, Australia
    J Psychiatry Neurosci 28:350-4. 2003
  100. ncbi request reprint Implications of lipid biology for the pathogenesis of schizophrenia
    Gregor E Berger
    Early Psychosis Prevention and Intervention Centre, MH SKY EPPIC, Victoria
    Aust N Z J Psychiatry 36:355-66. 2002
    ..Both aspects are proposed as being important in the pathogenesis of schizophrenia. The purpose of this paper is to examine the implications of lipid biology, in particular the role of essential fatty acids (EFA), for schizophrenia...
  101. ncbi request reprint The transition to psychosis: risk factors and brain changes
    Stephen J Wood
    Epidemiol Psichiatr Soc 13:137-40. 2004