Genomes and Genes
Anneke van der Walt
Affiliation: Royal Melbourne Hospital
- A double-blind, randomized, controlled study of botulinum toxin type A in MS-related tremorAnneke van der Walt
Royal Melbourne Hospital, Melbourne, Australia
Neurology 79:92-9. 2012..To evaluate the safety and efficacy of botulinum toxin type A in disabling multiple sclerosis (MS)-related upper limb tremor...
- Apolipoprotein genotype does not influence MS severity, cognition, or brain atrophyA van der Walt
Royal Melbourne Hospital, Department of Neurology, Parkville, Vic, Australia
Neurology 73:1018-25. 2009..In this study, we examine the influence of heterogeneity of the APOE gene on disease severity in a large, Australian, population-based MS cohort...
- Neuroprotection in multiple sclerosis: a therapeutic challenge for the next decadeAnneke van der Walt
The Royal Melbourne Hospital, Grattan St Parkville, Melbourne, Australia Centre for Neuroscience, University of Melbourne, Australia
Pharmacol Ther 126:82-93. 2010..In this article, we will discuss some of the principal therapeutic candidates that could provide neuroprotection in MS and emerging methodologies by which to test them...
- Heterogeneity at the HLA-DRB1 allelic variation locus does not influence multiple sclerosis disease severity, brain atrophy or cognitionAnneke van der Walt
Department of Neurology, The Royal Melbourne Hospital, Melbourne, Australia
Mult Scler 17:344-52. 2011..We examined the influence of DR15 and other common DRB1 alleles (DRB1*01 (DR1), DRB1*03 (DR3) and DRB1*04 (DR4) on MS severity in a large, Australian, population-based cohort...
- Multiple sclerosis susceptibility-associated SNPs do not influence disease severity measures in a cohort of Australian MS patientsCathy J Jensen
Howard Florey Institute, Melbourne, Australia
PLoS ONE 5:e10003. 2010..No associations were significant after correction for multiple testing. We found no evidence for the hypothesis that these new MS disease risk-associated SNPs influence disease severity...
- Optic nerve magnetisation transfer ratio after acute optic neuritis predicts axonal and visual outcomesYejun Wang
The Centre for Neuroscience Research, University of Melbourne, Parkville, Victoria, Australia
PLoS ONE 7:e52291. 2012..59, p = 0.02). In conclusion, these findings indicate that MTR flux after acute ON is predictive of axonal degeneration and visual disability outcomes...