Matthew A Sabin

Summary

Affiliation: Royal Children's Hospital
Country: Australia

Publications

  1. ncbi request reprint IGFBP-2 at the interface of growth and metabolism--implications for childhood obesity
    Matthew A Sabin
    Centre for Hormone Research and Department of Endocrinology and Diabetes Murdoch Childrens Research Institute, Royal Children s Hospital and University of Melbourne, Victoria, Australia
    Pediatr Endocrinol Rev 8:382-93. 2011
  2. doi request reprint Childhood obesity: Current and novel approaches
    Matthew A Sabin
    Murdoch Childrens Research Institute at The Royal Children s Hospital and University of Melbourne, Melbourne, Victoria 3052, Australia Electronic address
    Best Pract Res Clin Endocrinol Metab 29:327-38. 2015
  3. pmc The LIFE child study: a life course approach to disease and health
    Mirja Quante
    LIFE Leipzig Research Centre for Civilization Diseases, University of Leipzig, Philipp Rosenthalstrasse 27, D 04103 Leipzig, Germany
    BMC Public Health 12:1021. 2012
  4. doi request reprint Dietary monounsaturated fat in early life regulates IGFBP2: implications for fat mass accretion and insulin sensitivity
    Matthew A Sabin
    Centre for Hormone Research, Murdoch Childrens Research Institute and Royal Children s Hospital, Melbourne, Victoria, Australia
    Obesity (Silver Spring) 19:2374-81. 2011
  5. doi request reprint The role of pharmacotherapy in the prevention and treatment of paediatric metabolic syndrome--Implications for long-term health: part of a series on Pediatric Pharmacology, guest edited by Gianvincenzo Zuccotti, Emilio Clementi, and Massimo Molteni
    M A Sabin
    The Royal Children s Hospital, Murdoch Childrens Research Institute and University of Melbourne, Melbourne, Victoria, Australia
    Pharmacol Res 65:397-401. 2012
  6. ncbi request reprint Type 1 diabetes--still the commonest form of diabetes in children
    Matthew A Sabin
    Department of Endocrinology and Diabetes, Royal Children s Hospital, Melbourne, Victoria
    Aust Fam Physician 38:695-7. 2009
  7. doi request reprint Elevated glucose concentrations during an oral glucose tolerance test are associated with the presence of metabolic syndrome in childhood obesity
    M A Sabin
    Clinical Sciences, The University of Bristol and Royal Hospital for Children, Bristol, UK
    Diabet Med 25:289-95. 2008
  8. ncbi request reprint Precocious puberty in Turner syndrome
    Matthew A Sabin
    Department of Endocrinology and Diabetes, Royal Children s Hospital, Melbourne, Victoria, Australia
    J Paediatr Child Health 43:776-8. 2007
  9. doi request reprint Genetics of obesity and overgrowth syndromes
    Matthew A Sabin
    Murdoch Childrens Research Institute, Royal Children s Hospital, Flemington Road, Parkville, VIC 3052, Australia
    Best Pract Res Clin Endocrinol Metab 25:207-20. 2011
  10. pmc Shared care obesity management in 3-10 year old children: 12 month outcomes of HopSCOTCH randomised trial
    Melissa Wake
    Royal Children s Hospital, Parkville VIC 3052, Australia
    BMJ 346:f3092. 2013

Collaborators

Detail Information

Publications31

  1. ncbi request reprint IGFBP-2 at the interface of growth and metabolism--implications for childhood obesity
    Matthew A Sabin
    Centre for Hormone Research and Department of Endocrinology and Diabetes Murdoch Childrens Research Institute, Royal Children s Hospital and University of Melbourne, Victoria, Australia
    Pediatr Endocrinol Rev 8:382-93. 2011
    ....
  2. doi request reprint Childhood obesity: Current and novel approaches
    Matthew A Sabin
    Murdoch Childrens Research Institute at The Royal Children s Hospital and University of Melbourne, Melbourne, Victoria 3052, Australia Electronic address
    Best Pract Res Clin Endocrinol Metab 29:327-38. 2015
    ..Novel approaches are needed which take into consideration the complex physiology which regulates early childhood growth and the development of obesity in susceptible individuals. ..
  3. pmc The LIFE child study: a life course approach to disease and health
    Mirja Quante
    LIFE Leipzig Research Centre for Civilization Diseases, University of Leipzig, Philipp Rosenthalstrasse 27, D 04103 Leipzig, Germany
    BMC Public Health 12:1021. 2012
    ..Epidemiological studies together with new powerful research technologies present exciting opportunities to the elucidation of risk factor-outcome associations with potentially major consequences for prevention, diagnosis and treatment...
  4. doi request reprint Dietary monounsaturated fat in early life regulates IGFBP2: implications for fat mass accretion and insulin sensitivity
    Matthew A Sabin
    Centre for Hormone Research, Murdoch Childrens Research Institute and Royal Children s Hospital, Melbourne, Victoria, Australia
    Obesity (Silver Spring) 19:2374-81. 2011
    ..In conclusion, diets high in fat, but not sugar, promote visceral adiposity and insulin resistance in maturing pigs, with evidence that fatty acids have direct and indirect effects on IGFBP2 mRNA expression in muscle...
  5. doi request reprint The role of pharmacotherapy in the prevention and treatment of paediatric metabolic syndrome--Implications for long-term health: part of a series on Pediatric Pharmacology, guest edited by Gianvincenzo Zuccotti, Emilio Clementi, and Massimo Molteni
    M A Sabin
    The Royal Children s Hospital, Murdoch Childrens Research Institute and University of Melbourne, Melbourne, Victoria, Australia
    Pharmacol Res 65:397-401. 2012
    ....
  6. ncbi request reprint Type 1 diabetes--still the commonest form of diabetes in children
    Matthew A Sabin
    Department of Endocrinology and Diabetes, Royal Children s Hospital, Melbourne, Victoria
    Aust Fam Physician 38:695-7. 2009
    ....
  7. doi request reprint Elevated glucose concentrations during an oral glucose tolerance test are associated with the presence of metabolic syndrome in childhood obesity
    M A Sabin
    Clinical Sciences, The University of Bristol and Royal Hospital for Children, Bristol, UK
    Diabet Med 25:289-95. 2008
    ....
  8. ncbi request reprint Precocious puberty in Turner syndrome
    Matthew A Sabin
    Department of Endocrinology and Diabetes, Royal Children s Hospital, Melbourne, Victoria, Australia
    J Paediatr Child Health 43:776-8. 2007
    ..This case acts as a useful clinical vignette with which to highlight important aspects of diagnosis and treatment in children with TS, particularly in relation to future growth potential and issues relating to fertility...
  9. doi request reprint Genetics of obesity and overgrowth syndromes
    Matthew A Sabin
    Murdoch Childrens Research Institute, Royal Children s Hospital, Flemington Road, Parkville, VIC 3052, Australia
    Best Pract Res Clin Endocrinol Metab 25:207-20. 2011
    ..This review describes the genetic syndromes associated with obesity and overgrowth...
  10. pmc Shared care obesity management in 3-10 year old children: 12 month outcomes of HopSCOTCH randomised trial
    Melissa Wake
    Royal Children s Hospital, Parkville VIC 3052, Australia
    BMJ 346:f3092. 2013
    ....
  11. doi request reprint Infection-Related Hospitalization in Childhood and Adult Metabolic Outcomes
    David P Burgner
    Murdoch Children s Research Institute, Parkville, Victoria, Australia Department of Pediatrics, University of Melbourne, Parkville, Victoria, Australia Department of Pediatrics, Monash University, Department of Pediatric Infectious Diseases, Monash Children s Hospital, Clayton, Victoria, Australia
    Pediatrics 136:e554-62. 2015
    ..Therefore, we investigated whether hospitalization with childhood infection is associated with adult anthropometric and metabolic outcomes in a large, well-phenotyped longitudinal cohort...
  12. doi request reprint Increased Body Mass Index in Parent-Child Dyads Predicts the Offspring Risk of Meeting Bariatric Surgery Criteria
    Markus Juonala
    Murdoch Childrens Research Institute M J, M A S, D B, M C, Royal Children s Hospital, Parkville, Victoria 3052, Australia Research Centre of Applied and Preventive Cardiovascular Medicine J K, O T R, C G M and Department of Medicine M J, J S A V, University of Turku, 20520 Turku, Finland Division of Medicine M J, Turku University Hospital, 20520 Turku, Finland Department of Paediatrics M A S, D B, M C, University of Melbourne, Parkville, Victoria 3052, Australia Department of Paediatrics D B, Monash University, Clayton, Victoria 3168, Australia Departments of Clinical Physiology M K, Paediatrics N H K, and Clinical Chemistry T L, and Fimlab Laboratories T L, University of Tampere School of Medicine and Tampere University Hospital, 33500 Tampere, Finland Hospital for Children and Adolescents E J, University of Helsinki, Helsinki, 00029 HUS, Finland Department of Children and Adolescents P T, Oulu University Hospital, Department of Psychiatry
    J Clin Endocrinol Metab 100:4257-63. 2015
    ..Obesity in children is a major public health concern...
  13. doi request reprint Repeated Blood Pressure Measurements in Childhood in Prediction of Hypertension in Adulthood
    Mervi Oikonen
    From Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland M O, J N, C G M, O T R Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia C G M Department of Medicine, University of Turku and Division of Medicine, Turku University Hospital, Turku, Finland J S A V, M J Department of Pediatrics, Vaasa Central Hospital, Vaasa, Finland L T Department of Pediatrics, University of Oulu, Oulu, Finland L T Department of Clinical Physiology, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland T L Department of Pediatrics, University of Tampere and Tampere University Hospital, Tampere, Finland N H K Department of Pediatric Cardiology, Hospital for Children and Adolescents, University of Helsinki, Helsinki, Finland E J Department of Chronic Disease Prevention, National Institute for Health and Welfare, Turku, Finland A J Cardiology Department M C and Department of Endocrinology and Diabetes M A S, Murdoch Children s Research Institute, Royal Children s Hospital and University of Melbourne, Melbourne, Victoria, Department of Internal Medicine
    Hypertension 67:41-7. 2016
    ..Compared with a single measurement, the prediction of adult hypertension was enhanced by 2 observations of abnormal blood pressure in childhood/youth. ..
  14. doi request reprint Leptin enhances insulin sensitivity by direct and sympathetic nervous system regulation of muscle IGFBP-2 expression: evidence from nonrodent models
    Steven W Yau
    Centre for Hormone Research S W Y, V C R, G A W, M A S, Murdoch Childrens Research Institute and Royal Children s Hospital, and Department of Paediatrics S W Y, V C R, G A W, M A S, University of Melbourne, Melbourne, Victoria 3052, Australia Department of Physiology S W Y, B A H, I J C, M A S, Monash University, Melbourne, Victoria 3800, Australia and Institute of Sport, Exercise and Active Living and the College of Health and Biomedicine G K M, Victoria University, Melbourne, Victoria 3011, Australia
    Endocrinology 155:2133-43. 2014
    ..In summary, leptin regulates skeletal muscle IGFBP-2 by both direct peripheral and central (via the sympathetic nervous system) mechanisms, and these likely impact on peripheral insulin sensitivity and glucose metabolism. ..
  15. ncbi request reprint Which factors are associated with a successful outcome in a weight management programme for obese children?
    Matthew A Sabin
    Institute for Child Health, University of Bristol, and Bristol Royal Hospital for Children, Bristol, UK
    J Eval Clin Pract 13:364-8. 2007
    ....
  16. doi request reprint Low vitamin D is associated with hypertension in paediatric obesity
    Kung Ting Kao
    Department of Endocrinology and Diabetes, The Royal Children s Hospital, Melbourne, Victoria, Australia
    J Paediatr Child Health 51:1207-13. 2015
    ..The aim of this paper was to investigate the relationship between circulating 25-hydroxyvitamin D (25(OH)D) and cardio-metabolic risk factors in a large cohort of obese youth attending tertiary paediatric obesity services...
  17. doi request reprint Childhood metabolic syndrome, inflammation and carotid intima-media thickness. The Aboriginal Birth Cohort Study
    Markus Juonala
    Department of Medicine, University of Turku, Turku, Finland Division of Medicine, Turku University Hospital, Turku, Finland Murdoch Childrens Research Institute, Melbourne, Australia Electronic address
    Int J Cardiol 203:32-6. 2016
    ..We evaluated whether atherosclerotic changes associated with MetS in Australian Aboriginals are reversible in childhood. In addition, we investigated whether heightened inflammation is mediating the adverse effects of MetS...
  18. doi request reprint Early childhood hospitalisation with infection and subclinical atherosclerosis in adulthood: the Cardiovascular Risk in Young Finns Study
    David P Burgner
    Murdoch Childrens Research Institute, Royal Children s Hospital, 50 Flemington Road, Parkville 3052, Australia Department of Paediatrics, University of Melbourne, Grattan Street, Melbourne, Victoria 3010, Australia Department of Paediatrics, Monash University, 246 Clayton Road, Clayton, Victoria 3186, Australia Electronic address
    Atherosclerosis 239:496-502. 2015
    ..We examined the relationship between early childhood infections of sufficient severity to warrant hospitalisation, and markers of subclinical atherosclerosis in adulthood...
  19. doi request reprint Viewpoint article: Childhood obesity--looking back over 50 years to begin to look forward
    Matthew A Sabin
    Murdoch Childrens Research Institute, The Royal Children s Hospital, Melbourne, Victoria, Australia Department of Paediatrics, University of Melbourne, Melbourne, Victoria, Australia
    J Paediatr Child Health 51:82-6. 2015
    ....
  20. doi request reprint Monitoring height and weight: findings from a developmental paediatric service
    Tess Lionti
    Royal Children s Hospital, Murdoch Childrens Research Institute and University of Melbourne, Melbourne, Victoria, Australia
    J Paediatr Child Health 49:1063-8. 2013
    ..To assess the recording of weight and height in children with disabilities and identify subgroups at risk of being either underweight or overweight...
  21. doi request reprint How training affects Australian paediatricians' management of obesity
    Melissa Wake
    Centre for Community Child Health, Royal Children s Hospital Melbourne, Parkville, Vic, Australia
    Arch Dis Child 98:3-8. 2013
    ..We aimed to determine Australian paediatricians' self-reported competence and training in managing obesity and, in a linked patient-level audit, whether these predict rates of measurement and obesity diagnosis...
  22. ncbi request reprint Depot-specific effects of fatty acids on lipid accumulation in children's adipocytes
    Matthew A Sabin
    University of Bristol, Bristol, UK
    Biochem Biophys Res Commun 361:356-61. 2007
    ..3%[14.0]; p=0.01), but not visceral (Oleate 1000 microM: +16.2%[9.6]; p=0.25) adipocytes. These data suggest that saturated and unsaturated fatty acids may exert depot-specific effects on lipid accumulation...
  23. doi request reprint An observational study of type 2 diabetes within a large Australian tertiary hospital pediatric diabetes service
    Sandra D Ruhayel
    Department of Endocrinology and Diabetes at the Royal Children s Hospital, Parkville, Victoria, Australia
    Pediatr Diabetes 11:544-51. 2010
    ..Type 2 diabetes mellitus (T2DM) is emerging as a significant clinical problem within the pediatric population...
  24. doi request reprint Where should we measure waist circumference in clinically overweight and obese youth?
    Matthew A Sabin
    Department of Physiology, Monash University, Melbourne, Victoria, Australia Murdoch Childrens Research Institute, The Royal Children s Hospital, Melbourne, Victoria, Australia Department of Paediatrics, University of Melbourne, Melbourne, Victoria, Australia
    J Paediatr Child Health 50:519-24. 2014
    ..The objective of this study was to assess whether, in clinically overweight/obese youth, 'pannicular' WC better correlates with fat mass than a standard WC measurement...
  25. doi request reprint Overgrowth syndromes
    Orla M Neylon
    Murdoch Childrens Research Institute, Royal Children s Hospital and University of Melbourne, Parkville, Victoria, Australia
    Curr Opin Pediatr 24:505-11. 2012
    ..Intensive research in these divergent areas, and particularly in the field of genetics, continues to clarify the molecular basis of disorders which result in overgrowth, and it is therefore timely to provide a review of these findings...
  26. doi request reprint Insulin and BMI as predictors of adult type 2 diabetes mellitus
    Matthew A Sabin
    Murdoch Childrens Research Institute, Royal Children s Hospital and University of Melbourne, Melbourne, Australia
    Pediatrics 135:e144-51. 2015
    ..Our objective was to determine whether fasting insulin concentrations in childhood associate with later T2DM...
  27. pmc A shared-care model of obesity treatment for 3-10 year old children: protocol for the HopSCOTCH randomised controlled trial
    Melissa Wake
    Royal Children s Hospital, Parkville, Vic, Australia
    BMC Pediatr 12:39. 2012
    ..HopSCOTCH (the Shared Care Obesity Trial in Children) will determine whether a shared-care model, in which paediatric obesity specialists co-manage obesity with general practitioners, can improve adiposity in obese children...
  28. pmc Clinical measures of adiposity and percentage fat loss: which measure most accurately reflects fat loss and what should we aim for?
    Linda P Hunt
    Department of Endocrinology, Diabetes and Metabolism, Bristol Royal Hospital for Children and University of Bristol, Bristol, UK
    Arch Dis Child 92:399-403. 2007
    ..To determine which clinical measure of childhood obesity should be monitored to best reflect change in adiposity in a weight management programme and estimate the degree of change needed to be relatively certain of fat reduction...
  29. doi request reprint Childhood obesity
    M A Sabin
    Royal Children s Hospital and Murdoch Childrens Research Institute, Melbourne, Australia
    Front Horm Res 36:85-96. 2008
    ....
  30. ncbi request reprint Fasting nonesterified fatty acid profiles in childhood and their relationship with adiposity, insulin sensitivity, and lipid levels
    Matthew A Sabin
    Clinical Sciences South Bristol, University of Bristol and Bristol Royal Hospital for Children, Bristol, United Kingdom
    Pediatrics 120:e1426-33. 2007
    ....