Research Topics
Species | Anne Louise PonsonbySummaryAffiliation: Royal Children's Hospital Country: Australia Publications
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Detail Information
Publications
Poor stereoacuity among children with poor literacy: prevalence and associated factorsAnne Louise Ponsonby
Murdoch Children s Research Institute, Royal Children s Hospital, Melbourne, Victoria, Australia
Optom Vis Sci 90:75-83. 2013....- Offspring number, pregnancy, and risk of a first clinical demyelinating event: the AusImmune StudyA L Ponsonby
Murdoch Childrens Research Institute, Melbourne, Australia
Neurology 78:867-74. 2012..To examine the association between past pregnancy, offspring number, and first clinical demyelination risk... 
Vitamin D status during pregnancy and aspects of offspring healthAnne Louise Ponsonby
Murdoch Childrens Research Institute, Royal Children s Hospital, Parkville, Melbourne, Australia
Nutrients 2:389-407. 2010..The evidence to date supports that women should be monitored and treated for vitamin D deficiency during pregnancy but optimal and upper limit serum 25(OH)D levels during pregnancy are not known...- Measurement of Epstein-Barr virus DNA load using a novel quantification standard containing two EBV DNA targets and SYBR Green I dyeMeav Lang J Lay
Virology Department, Centre for Infectious Diseases and Microbiology Laboratory Services, Institute of Clinical Pathology and Medical Research, Institute Road, Westmead Hospital, Westmead 2145, New South Wales, Australia
Virol J 7:252. 2010..EBV DNA loads and viral capsid antigen (VCA) IgG antibody titres were also quantified on a population sample... - Association between early-life factors and risk of child-onset Crohn's disease among Victorian children born 1983-1998: a birth cohort studyAnne Louise Ponsonby
Murdoch Childrens Research Institute, Royal Childrens Hospital, Melbourne, Victoria, Australia
Inflamm Bowel Dis 15:858-66. 2009..Our objective was to examine the temporal change in CD incidence by period of birth and the extent that this could be attributed to perinatal characteristics associated with higher CD risk... - Asthma onset prior to multiple sclerosis and the contribution of sibling exposure in early lifeA L Ponsonby
Murdoch Childrens Research Institute, Royal Children s Hospital, Melbourne, Australia
Clin Exp Immunol 146:463-70. 2006..The link between early life sibling exposure and the immune response to herpes group viral antigens is consistent with a protective role for early life infections... 
UVR, vitamin D and three autoimmune diseases--multiple sclerosis, type 1 diabetes, rheumatoid arthritisA L Ponsonby
Murdoch Childrens Research Institute, Royal Children s Hospital, Parkville, Melbourne, Australia
Photochem Photobiol 81:1267-75. 2005..Further, we discuss how associated genetic studies may assist the accumulation of evidence with regard to the possible causal role of low UVR exposure and/or low vitamin D status in the development of these diseases...- Children with low literacy and poor stereoacuity: an evaluation of complex interventions in a community-based randomized trialAnne Louise Ponsonby
Murdoch Childrens Research Institute, Parkville, Victoria 3052, Australia
Ophthalmic Epidemiol 16:311-21. 2009..To assess, among children with low literacy and poor stereoacuity, the efficacy of two intervention programs on child vision and education compared to a control program... - A case-sibling assessment of the association between skin pigmentation and other vitamin D-related factors and type 1 diabetes mellitusAnne Louise Ponsonby
Murdoch Children s Research Institute, Royal Children s Hospital, Department of Paediatrics, University of Melbourne, Melbourne, Vic, Australia
Photochem Photobiol 85:1267-70. 2009..The previously demonstrated association between light skin pigmentation and T1DM risk was evident even in this comparison across sibling pairs. Further work on past UVR exposure and related factors such as skin pigmentation is required... - Adiposity gain during childhood, ACE I/D polymorphisms and metabolic outcomesAnne Louise Ponsonby
Murdoch Childrens Research Institute, Royal Children s Hospital, Melbourne, Victoria, Australia
Obesity (Silver Spring) 16:2141-7. 2008..Further work is required to confirm and extend these findings... - Variation in associations between allelic variants of the vitamin D receptor gene and onset of type 1 diabetes mellitus by ambient winter ultraviolet radiation levels: a meta-regression analysisAnne Louise Ponsonby
Murdoch Childrens Research Institute, Royal Children s Hospital, Melbourne, Australia
Am J Epidemiol 168:358-65. 2008..They suggest that environmental UVR may influence the association between VDR genotype and T1DM risk. Further work on VDR polymorphisms and T1DM should concomitantly examine the roles of past UVR exposure and vitamin D status... - Objectively measured physical activity and the subsequent risk of incident dysglycemia: the Australian Diabetes, Obesity and Lifestyle Study (AusDiab)Anne Louise Ponsonby
Murdoch Children s Research Institute, Royal Children s Hospital, Melbourne, Victoria, Australia
Diabetes Care 34:1497-502. 2011..To investigate pedometer-measured physical activity (PA) in 2000 and change in PA over 5 years with subsequent risk of dysglycemia by 2005... - Infant anthropometry, early life infection, and subsequent risk of type 1 diabetes mellitus: a prospective birth cohort studyAnne Louise Ponsonby
Murdoch Childrens Research Institute, Royal Children s Hospital, Melbourne, Victoria, Australia
Pediatr Diabetes 12:313-21. 2011..In this Tasmanian infant cohort, early upper respiratory infection has been associated with higher asthma risk... - APOE genotype and cardio-respiratory fitness interact to determine adiposity in 8-year-old children from the Tasmanian Infant Health SurveyJustine A Ellis
Environmental and Genetic Epidemiology Research, Murdoch Childrens Research Institute, Parkville, Australia
PLoS ONE 6:e26679. 2011..APOE4 and cardiorespitatory fitness could interact to influence child adiposity. In studies addressing the genetic determinants of childhood obesity, the context of child fitness should also be taken into account... - Associations of birth weight with ocular biometry, refraction, and glaucomatous endophenotypes: the Australian Twins Eye StudyCong Sun
Centre for Eye Research, University of Melbourne, Department of Ophthalmology, Royal Victorian Eye and Ear Hospital, Melbourne, Australia
Am J Ophthalmol 150:909-16. 2010..To examine the relationship of birth weight with ocular measures in a Caucasian twin population... - Vitamin D deficiency and pregnancy: from preconception to birthSharon Lewis
Public Health Genetics, Murdoch Childrens Research Institute, Royal Children s Hospital, Melbourne, Australia
Mol Nutr Food Res 54:1092-102. 2010..This review outlines the emerging evidence that maternal vitamin D status during pregnancy is important for the health of the mother and offspring across a range of possible health outcomes... - Independent replication analysis of genetic loci with previous evidence of association with juvenile idiopathic arthritisJustine A Ellis
Genes, Environment and Complex Disease, Murdoch Childrens Research Institute, 50 Flemington Rd, Parkville, Vic, 3052, Australia
Pediatr Rheumatol Online J 11:12. 2013.... - CLARITY - ChiLdhood Arthritis Risk factor Identification sTudYJustine A Ellis
Genes, Environment and Complex Disease, Murdoch Childrens Research Institute, Parkville, Vic, Australia
Pediatr Rheumatol Online J 10:37. 2012..abstract:.. - Increasing the accuracy of peanut allergy diagnosis by using Ara h 2Thanh D Dang
Murdoch Childrens Research Institute, Parkville, Australia
J Allergy Clin Immunol 129:1056-63. 2012..Ara h 2 is the dominant peanut allergen detected in 90% to 100% of patients with peanut allergy and could help improve diagnosis... - Prevalence of challenge-proven IgE-mediated food allergy using population-based sampling and predetermined challenge criteria in infantsNicholas J Osborne
Murdoch Childrens Research Institute, Melbourne, Australia
J Allergy Clin Immunol 127:668-76.e1-2. 2011..Several indicators suggest that food allergy in infants is common and possibly increasing. Few studies have used oral food challenge to measure this phenomenon at the population level... - Maternal alcohol intake and offspring pulse wave velocityRuth Morley
Department of Paediatrics, University of Melbourne, Clayton, Vic, Australia
Neonatology 97:204-11. 2010..In human adults, alcohol intake affects arterial stiffness... - Effect of including environmental data in investigations of gene-disease associations in the presence of qualitative interactionsElizabeth Williamson
Murdoch Childrens Research Institute, Parkville, Victoria, Australia
Genet Epidemiol 34:552-60. 2010..This comparative increase in power remains in the presence of likely levels of misclassification of either the gene or environmental exposure... - A temporal decline in asthma but not eczema prevalence from 2000 to 2005 at school entry in the Australian Capital Territory with further consideration of country of birthAnne Louise Ponsonby
Murdoch Childrens Research Institute, Royal Children s Hospital, Melbourne, Australia
Int J Epidemiol 37:559-69. 2008..Here, we examined trends in asthma prevalence using serial annual data and further examine the importance of country of birth... - Obesity and asthma at school entry: Co-morbidities and temporal trendsSanthamma James
School of Arts and Sciences, St Patrick s Campus, Australian Catholic University, Melbourne, Australia
J Paediatr Child Health 49:E273-80. 2013..The objective is to examine the temporal trends for the prevalence of obesity and other childhood disorders and consider the extent to which associations between asthma and other co-morbidities can be accounted for by body mass index... - Effect of birth parameters on retinal vascular caliber: the Twins Eye Study in TasmaniaCong Sun
Centre for Eye Research Australia, University of Melbourne, Melbourne, Australia
Hypertension 53:487-93. 2009..The independent effect of shorter birth length on retinal arteriolar caliber supports a role for twin-specific supply line factors affecting fetal growth on vascular structure... - Vitamin D insufficiency is associated with challenge-proven food allergy in infantsKatrina J Allen
Murdoch Childrens Research Institute, Parkville, Victoria, Australia Department of Paediatrics, The University of Melbourne, Parkville, Victoria, Australia Department of Allergy and Immunology, The Royal Children s Hospital, Parkville, Victoria, Australia Electronic address
J Allergy Clin Immunol 131:1109-1116.e6. 2013..Epidemiological evidence has shown that pediatric food allergy is more prevalent in regions further from the equator, suggesting that vitamin D insufficiency may play a role in this disease... - Cardiovascular disease risk in the offspring of diabetic women: the impact of the intrauterine environmentLaura J Marco
Pregnancy Research Centre, The Royal Women s Hospital, Parkville, VIC 3052, Australia
Exp Diabetes Res 2012:565160. 2012..Initiating disease prevention aimed at the developing fetus during the antenatal period may optimise community health outcomes... - Genome-scale case-control analysis of CD4+ T-cell DNA methylation in juvenile idiopathic arthritis reveals potential targets involved in diseaseJustine A Ellis
Genes, Environment and Complex Disease, Murdoch Childrens Research Institute, 50 Flemington Rd, Parkville, Vic, Australia
Clin Epigenetics 4:20. 2012..abstract:.. - Can early introduction of egg prevent egg allergy in infants? A population-based studyJennifer J Koplin
Murdoch Childrens Research Institute, Parkville, Australia
J Allergy Clin Immunol 126:807-13. 2010..Infant feeding guidelines have long recommended delaying introduction of solids and allergenic foods to prevent allergy in high-risk infants, despite a paucity of evidence... - Decline in physical fitness from childhood to adulthood associated with increased obesity and insulin resistance in adultsTerence Dwyer
Murdoch Children s Research Institute, Royal Children s Hospital, Parkville, Melbourne, Australia
Diabetes Care 32:683-7. 2009..To examine how fitness in both childhood and adulthood is associated with adult obesity and insulin resistance... - The Peri/Postnatal Epigenetic Twins Study (PETS)Yuk Jing Loke
Department of Paediatrics, Early Life Epigenetics Group, Murdoch Childrens Research Institute, Royal Children s Hospital, Melbourne, Australia
Twin Res Hum Genet 16:13-20. 2013.... - Possible environmental determinants of juvenile idiopathic arthritisJustine A Ellis
Murdoch Children s Research Institute, Royal Children s Hospital, Parkville, Victoria 3052, Australia
Rheumatology (Oxford) 49:411-25. 2010..Finally, we discuss future directions including practical study designs to more comprehensively test hypotheses and provide new insight into this important area of research... - Ecologic analysis of some immune-related disorders, including type 1 diabetes, in Australia: latitude, regional ultraviolet radiation, and disease prevalenceJudith A Staples
National Center for Epidemiology and Population Health, The Australian National University, Canberra, Australian Capital Territory, Australia
Environ Health Perspect 111:518-23. 2003..In light of this study, analytic epidemiologic studies investigating risk of immune disorders in relation to personal UVR exposure in humans are required... - Exposure to infant siblings during early life and risk of multiple sclerosisAnne Louise Ponsonby
National Centre for Epidemiology and Population Health, The Australian National University, Canberra ACT, Australia
JAMA 293:463-9. 2005..Viral infection has also been implicated in the pathogenesis of multiple sclerosis (MS)... - Re: Birth order, atopy, and risk of non-Hodgkin lymphomaAndrew Kemp
J Natl Cancer Inst 97:1475; author reply 1475-6. 2005 - Considering the potential benefits as well as adverse effects of sun exposure: can all the potential benefits be provided by oral vitamin D supplementation?Robyn M Lucas
National Centre for Epidemiology and Population Health, The Australian National University, Canberra 0200, Australia
Prog Biophys Mol Biol 92:140-9. 2006..Thus maintaining current sun avoidance policies while supplementing food with vitamin D may not be sufficient to avoid the risks of insufficient exposure to UVR... - Ultraviolet radiation and autoimmune disease: insights from epidemiological researchAnne Louise Ponsonby
National Centre for Epidemiology and Population Health, The Australian National University, Canberra ACT 0200, Australia
Toxicology 181:71-8. 2002..In particular, the possible contribution of an UVR-induced increase in serum vitamin D (1,25(OH)2D3) levels in the beneficial immunomodulation of these diseases is discussed... - The high prevalence of vitamin D insufficiency across Australian populations is only partly explained by season and latitudeIngrid A F van der Mei
Menzies Research Institute, University of Tasmania, Hobart, Australia
Environ Health Perspect 115:1132-9. 2007..Inadequate sun exposure and dietary vitamin D intake can result in vitamin D insufficiency. However, limited data are available on actual vitamin D status and predictors in healthy individuals in different regions and by season... - Mid-life stress is associated with both up- and down-regulation of markers of humoral and cellular immunityRobyn M Lucas
National Centre for Epidemiology and Population Health, The Australian National University, Canberra, Australia
Stress 10:351-61. 2007.... - CTLA-4 and multiple sclerosis: the A49G single nucleotide polymorphism shows no association with multiple sclerosis in a Southern Australian populationBradley N Wray
Menzies Research Institute, University of Tasmania, Tasmania, Australia
J Neuroimmunol 196:139-42. 2008..There were no significant (P<0.05) associations between the A49G genotype and risk of MS, either before or after stratification for presence of the DR15 haplotype... - Ultraviolet radiation and health: friend and foeRobyn M Lucas
National Centre for Epidemiology and Population Health, Australian National University, Canberra, ACT
Med J Aust 177:594-8. 2002..There is ongoing research examining the effects of UVR exposure on immune function, including an examination of the possible role of lack of UVR exposure in the aetiology of multiple sclerosis and type 1 diabetes mellitus... - Parental smoking and infant respiratory infection: how important is not smoking in the same room with the baby?Leigh Blizzard
Menzies Centre for Population Health Research, University of Tasmania, Hobart, Australian Capital Territory, Australia
Am J Public Health 93:482-8. 2003..We sought to quantify the effect of good smoking hygiene on infant risk of respiratory tract infection in the first 12 months of life... - The use of mutually exclusive categories for atopic sensitization: a contrasting effect for family size on house dust mite sensitization compared with ryegrass sensitizationAnne Louise Ponsonby
National Center for Epidemiology and Population Health, Australian National University, Canberra, Australia
Pediatr Allergy Immunol 14:81-90. 2003..The use of mutually exclusive categories for allergen sensitization will assist future work on child atopic disease... - Synthetic bedding and wheeze in childhoodAnne Louise Ponsonby
National Centre for Epidemiology and Population Health, Australian National University, Canberra, Australia
Epidemiology 14:37-44. 2003..Prospective data on infant bedding have not been available... - Proactive asthma care in childhood: general practice based randomised controlled trialNicholas J Glasgow
Academic Unit of General Practice and Community Care, Canberra Clinical School of the University of Sydney, PO Box 254, Canberra, ACT 2614, Australia
BMJ 327:659. 2003..To assess the feasibility and effectiveness of a general practice based, proactive system of asthma care in children... - The bedding environment, sleep position, and frequent wheeze in childhoodAnne Louise Ponsonby
National Centre for Epidemiology and Population Health, Australian National University, Canberra ACT, Australia
Pediatrics 113:1216-22. 2004..Synthetic quilt use has been associated with increased childhood wheeze in previous studies. Our aim was to examine whether the adverse effect of synthetic quilt use on frequent wheeze differed by usual sleep position... - What affects your MS? Responses to an anonymous, Internet-based epidemiological surveyRex D Simmons
Canberra Hospital, Canberra, ACT 2606 Australia
Mult Scler 10:202-11. 2004..The present study provides new information from people with MS on factors that may influence symptoms or clinical course. This information will now be used in the design of formal epidemiological cohort studies... - Which clinical subgroups within the spectrum of child asthma are attributable to atopy?Anne Louise Ponsonby
National Center for Epidemiology and Population Health, Australian National University, Australian Capital Territory, Australia
Chest 121:135-42. 2002..The contribution of atopy to childhood asthma has been debated. We aimed to examine the relationship between atopy and asthma, taking into account differences in respiratory symptoms and disease severity... - Birth order, infection in early life, and multiple sclerosisAnne-Louise Ponsonby
Lancet Neurol 4:793-4; author reply 795. 2005 - Infant sleeping environment and asthma at 7 years: a prospective cohort studyLeigh F Trevillian
National Centre for Epidemiology and Population Health, Australian National University, Canberra, Australia
Am J Public Health 95:2238-45. 2005..CONCLUSIONS: Our results show that bedding exposures in infancy are prospectively associated with childhood wheezing and that home environmental conditions may modify this association... - The effect of season on cytokine expression in multiple sclerosis and healthy subjectsNiall Stewart
School of Medicine, University of Tasmania, Hobart, Tasmania, Australia
J Neuroimmunol 188:181-6. 2007..Untreated MS cases had a summer excess of Il-10, whereas those treated with Interferon-beta had lower levels of all cytokines, and displayed no seasonal effect... - Adherence to the immunomodulatory drugs for multiple sclerosis: contrasting factors affect stopping drug and missing dosesHelen Tremlett
Faculty of Medicine Neurology, University of British Columbia, Canada
Pharmacoepidemiol Drug Saf 17:565-76. 2008..We examined both levels of non-adherence-stopping IMD and missing doses... - Maternal vitamin D in pregnancy may influence not only offspring bone mass but other aspects of musculoskeletal health and adiposityJulie A Pasco
Epidemiology and Biostatistics Unit, Department of Clinical and Biomedical Sciences Barwon Health, The University of Melbourne, Australia
Med Hypotheses 71:266-9. 2008..We suggest that there is a clear rationale for randomised clinical trials to assess the potential benefits and harmful effects of vitamin D supplementation during pregnancy... - Misclassification due to body hair and seasonal variation on melanin density estimates for skin type using spectrophotometryIngrid A F van der Mei
Cooperative Research Centre for Discovery of Genes for Common Human Diseases at the Menzies Centre for Population Health Research, University of Tasmania, Tasmania, Australia
J Photochem Photobiol B 68:45-52. 2002..However, both sources of error can be reduced by careful attention to key aspects of study design...