Nicholas J Osborne

Summary

Affiliation: Royal Children's Hospital
Country: Australia

Publications

  1. doi request reprint Iron-overload-related disease in HFE hereditary hemochromatosis
    Katrina J Allen
    Murdoch Children s Research Institute, University of Melbourne, Melbourne, Australia
    N Engl J Med 358:221-30. 2008
  2. doi request reprint Prevalence of challenge-proven IgE-mediated food allergy using population-based sampling and predetermined challenge criteria in infants
    Nicholas J Osborne
    Murdoch Childrens Research Institute, Melbourne, Australia
    J Allergy Clin Immunol 127:668-76.e1-2. 2011
  3. pmc Dermatitis associated with exposure to a marine cyanobacterium during recreational water exposure
    Nicholas J Osborne
    Gut and Liver, Murdoch Childrens Research Institute, Flemington Road, Melbourne, Australia
    BMC Dermatol 8:5. 2008
  4. pmc HFE C282Y homozygotes are at increased risk of breast and colorectal cancer
    Nicholas J Osborne
    Gut and Liver, Murdoch Childrens Research Institute, Melbourne, Vic, Australia
    Hepatology 51:1311-8. 2010
  5. pmc HFE Cys282Tyr homozygotes with serum ferritin concentrations below 1000 microg/L are at low risk of hemochromatosis
    Katrina J Allen
    Murdoch Childrens Research Institute, Melbourne, Australia
    Hepatology 52:925-33. 2010
  6. doi request reprint HFE C282Y homozygosity is associated with an increased risk of total hip replacement for osteoarthritis
    Yuanyuan Wang
    Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Alfred Hospital, Melbourne, Victoria, Australia
    Semin Arthritis Rheum 41:872-8. 2012
  7. ncbi request reprint The natural history of serum iron indices for HFE C282Y homozygosity associated with hereditary hemochromatosis
    Lyle C Gurrin
    Centre for MEGA Epidemiology, School of Population Health, The University of Melbourne, Melbourne, Australia
    Gastroenterology 135:1945-52. 2008
  8. ncbi request reprint The natural history and clinical predictors of egg allergy in the first 2 years of life: a prospective, population-based cohort study
    Rachel L Peters
    Murdoch Childrens Research Institute, Parkville, Australia Department of Paediatrics, University of Melbourne, Parkville, Australia
    J Allergy Clin Immunol 133:485-91. 2014
  9. doi request reprint Vitamin D insufficiency is associated with challenge-proven food allergy in infants
    Katrina J Allen
    Murdoch Childrens Research Institute, Department of Paediatrics, The University of Melbourne, Department of Allergy and Immunology, The Royal Children s Hospital, Parkville, Victoria, Australia
    J Allergy Clin Immunol 131:1109-16, 1116.e1-6. 2013
  10. doi request reprint Can early introduction of egg prevent egg allergy in infants? A population-based study
    Jennifer J Koplin
    Murdoch Childrens Research Institute, Parkville, Australia
    J Allergy Clin Immunol 126:807-13. 2010

Collaborators

Detail Information

Publications10

  1. doi request reprint Iron-overload-related disease in HFE hereditary hemochromatosis
    Katrina J Allen
    Murdoch Children s Research Institute, University of Melbourne, Melbourne, Australia
    N Engl J Med 358:221-30. 2008
    ..Diseases related to iron overload develop in some C282Y homozygotes, but the extent of the risk is controversial...
  2. doi request reprint Prevalence of challenge-proven IgE-mediated food allergy using population-based sampling and predetermined challenge criteria in infants
    Nicholas J Osborne
    Murdoch Childrens Research Institute, Melbourne, Australia
    J Allergy Clin Immunol 127:668-76.e1-2. 2011
    ..Several indicators suggest that food allergy in infants is common and possibly increasing. Few studies have used oral food challenge to measure this phenomenon at the population level...
  3. pmc Dermatitis associated with exposure to a marine cyanobacterium during recreational water exposure
    Nicholas J Osborne
    Gut and Liver, Murdoch Childrens Research Institute, Flemington Road, Melbourne, Australia
    BMC Dermatol 8:5. 2008
    ..majuscula. This coincided with the presence of a bloom of L. majuscula...
  4. pmc HFE C282Y homozygotes are at increased risk of breast and colorectal cancer
    Nicholas J Osborne
    Gut and Liver, Murdoch Childrens Research Institute, Melbourne, Vic, Australia
    Hepatology 51:1311-8. 2010
    ..16; 95% CI = 0.74, 1.84), or prostate cancer (HR = 1.08; 95% CI = 0.68, 1.70). Conclusion: HFE C282Y homozygotes have twice the risk of colorectal and breast cancer compared with those individuals without the C282Y variant...
  5. pmc HFE Cys282Tyr homozygotes with serum ferritin concentrations below 1000 microg/L are at low risk of hemochromatosis
    Katrina J Allen
    Murdoch Childrens Research Institute, Melbourne, Australia
    Hepatology 52:925-33. 2010
    ..22) and for normal SF was 6% (arthritis medicine use, 95% confidence interval = -3%, 16%; P = 0.11)...
  6. doi request reprint HFE C282Y homozygosity is associated with an increased risk of total hip replacement for osteoarthritis
    Yuanyuan Wang
    Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Alfred Hospital, Melbourne, Victoria, Australia
    Semin Arthritis Rheum 41:872-8. 2012
    ..Total joint replacement is considered a surrogate measure for symptomatic end-stage osteoarthritis. We examined the relationship between HFE gene mutations and risk of total hip and knee replacement using a prospective cohort study...
  7. ncbi request reprint The natural history of serum iron indices for HFE C282Y homozygosity associated with hereditary hemochromatosis
    Lyle C Gurrin
    Centre for MEGA Epidemiology, School of Population Health, The University of Melbourne, Melbourne, Australia
    Gastroenterology 135:1945-52. 2008
    ..We characterized the development of elevated iron measures in C282Y homozygotes followed for 12 years...
  8. ncbi request reprint The natural history and clinical predictors of egg allergy in the first 2 years of life: a prospective, population-based cohort study
    Rachel L Peters
    Murdoch Childrens Research Institute, Parkville, Australia Department of Paediatrics, University of Melbourne, Parkville, Australia
    J Allergy Clin Immunol 133:485-91. 2014
    ..There is a paucity of data examining the natural history of and risk factors for egg allergy persistence, the most common IgE-mediated food allergy in infants...
  9. doi request reprint Vitamin D insufficiency is associated with challenge-proven food allergy in infants
    Katrina J Allen
    Murdoch Childrens Research Institute, Department of Paediatrics, The University of Melbourne, Department of Allergy and Immunology, The Royal Children s Hospital, Parkville, Victoria, Australia
    J Allergy Clin Immunol 131:1109-16, 1116.e1-6. 2013
    ..Epidemiological evidence has shown that pediatric food allergy is more prevalent in regions further from the equator, suggesting that vitamin D insufficiency may play a role in this disease...
  10. doi request reprint Can early introduction of egg prevent egg allergy in infants? A population-based study
    Jennifer J Koplin
    Murdoch Childrens Research Institute, Parkville, Australia
    J Allergy Clin Immunol 126:807-13. 2010
    ..Infant feeding guidelines have long recommended delaying introduction of solids and allergenic foods to prevent allergy in high-risk infants, despite a paucity of evidence...