Research Topics
| Terrie InderSummaryAffiliation: Royal Children's Hospital Country: Australia Publications
| Collaborators
|
Detail Information
Publications
Non-human primate models of neonatal brain injuryTerrie Inder
Department of Neurology, Royal Women s and Royal Children s Hospital, Murdoch Children s Research Institute, Parkville, Victoria, Australia
Semin Perinatol 28:396-404. 2004..This article summarizes both models of brain injury. The histologic findings from the models are compared with neuropathological studies in human infants...- Abnormal cerebral structure is present at term in premature infantsTerrie E Inder
Murdoch Children s Research Institute, Royal Women s Hospital, University of Melbourne, Melbourne, Australia
Pediatrics 115:286-94. 2005..However, there is a limited understanding of the nature of the cerebral abnormality underlying these adverse neurologic outcomes... - Randomized trial of systemic hypothermia selectively protects the cortex on MRI in term hypoxic-ischemic encephalopathyTerrie E Inder
Division of Newborn Services, Royal Women s Hospital, Neonatal Neurology, Royal Children s Hospital, Melbourne, Australia
J Pediatr 145:835-7. 2004..036), which may indicate differing regional benefit from systemic hypothermia... - Elevated free radical products in the cerebrospinal fluid of VLBW infants with cerebral white matter injuryTerrie Inder
The Murdoch Children s Research Institute and Howard Florey Institute and Royal Women s and Royal Children s Hospital, Melbourne, Australia
Pediatr Res 52:213-8. 2002..These preliminary data provide evidence of an association of elevated oxidative products during the evolution of white matter injury in the human premature infant... - Investigation of cerebral development and injury in the prematurely born primate by magnetic resonance imaging and histopathologyTerrie Inder
Neonatal Neurology, Royal Women s and Royal Children s Hospitals, Murdoch Children s Research Institute, Parkville, Australia
Dev Neurosci 27:100-11. 2005..The prematurely born baboon appears an important model for the study of preterm human birth... 
The effects of postnatal estrogen therapy on brain development in preterm baboonsSandra Rees
Department of Anatomy and Cell Biology, University of Melbourne, Victoria, Australia
Am J Obstet Gynecol 204:177.e8-14. 2011..Estrogen receptors are present within the fetal brain, suggesting that estrogens may exert an influence on cerebral development. Loss of placentally derived estrogen in preterm birth may impair development...- Cerebellar development in a baboon model of preterm delivery: impact of specific ventilatory regimesSandra M Rees
Department of Anatomy Cell Biology, University of Melbourne, Victoria, Australia
J Neuropathol Exp Neurol 68:605-15. 2009..001) and was higher in DnCPAP than EnCPAP animals (p < 0.05). These results indicate that respiratory regimens can influence cerebellar development and that early compared with delayed extubation to nCPAP seems to be beneficial... 
Preventive care at home for very preterm infants improves infant and caregiver outcomes at 2 yearsAlicia J Spittle
Murdoch Childrens Research Institute, Victoria Infant Brain Studies, Melbourne, Australia
Pediatrics 126:e171-8. 2010..The objective of this study was to determine the effects of preventive care at home on child development and primary caregiver mental health at 2 years of age...- Early sensitivity training for parents of preterm infants: impact on the developing brainJeannette Milgrom
Department of Clinical and Health Psychology, Austin Health, Victoria, Australia
Pediatr Res 67:330-5. 2010..Thus, sensitivity training for parents in the NICU is associated with improved cerebral white matter micro-structural development in preterm infants... - The pattern of cerebral injury in a primate model of preterm birth and neonatal intensive careSandra Dieni
Department of Anatomy and Cell Biology, University of Melbourne, Parkville, Victoria, Australia
J Neuropathol Exp Neurol 63:1297-309. 2004..These data suggest that the premature baboon is a model with similarities in maturation and pattern of cerebral injury to the human infant that may provide useful insights of relevance to the human preterm infant... - Fetal and neonatal origins of altered brain developmentSandra Rees
Department of Anatomy and Cell Biology, University of Melbourne, Victoria 3010, Australia
Early Hum Dev 81:753-61. 2005..Defining the causes, patterns and mechanisms of brain injury is crucial if we are to develop rational neuroprotective strategies to reduce the burden of altered brain growth and poor functional and behavioural outcomes... - A tracking approach to parcellation of the cerebral cortexChris Adamson
Howard Florey Institute, University of Melbourne, Australia
Med Image Comput Comput Assist Interv 8:294-301. 2005..This model-based parcellation method, evaluated here on a set of histological images of the cortex, is extensible to 3-D images... - Cerebral outcomes in a preterm baboon model of early versus delayed nasal continuous positive airway pressureMichelle Loeliger
Department of Anatomy and Cell Biology, University of Melbourne, 3010, Victoria, Australia
Pediatrics 118:1640-53. 2006.... - Quality of general movements is related to white matter pathology in very preterm infantsAlicia J Spittle
Victorian Infant Brain Studies, Murdoch Childrens Research Institute, 2nd Floor, Royal Children s Hospital, Flemington Road, Parkville, Melbourne, Australia 3052
Pediatrics 121:e1184-9. 2008..The objective of this study was to determine the association between MRI-defined cerebral abnormalities and general movements at 1 and 3 months' corrected age in infants who were born very preterm... - Single versus bihemispheric amplitude-integrated electroencephalography in relation to cerebral injury and outcome in the term encephalopathic infantShelly Lavery
Victorian Infant Brain Study Group, and Murdoch Childrens Research Institute, The Royal Children s Hospital Melbourne, Victoria, Australia
J Paediatr Child Health 44:285-90. 2008..New bedside aEEG devices with more channels are entering the neonatal environment. Little data are available to compare the utility of two channels (B-aEEG) with that of an S-aEEG recording... - Perinatal and neonatal ischaemic stroke: a reviewRod W Hunt
Department of Neonatal Medicine, Royal Children's Hospital, Flemington Road, Parkville VIC 3052, Australia
Thromb Res 118:39-48. 2006 - Use of 2-channel bedside electroencephalogram monitoring in term-born encephalopathic infants related to cerebral injury defined by magnetic resonance imagingDivyen K Shah
Department of Neonatology, Royal Children's and Royal Women's Hospitals, Melbourne, Australia
Pediatrics 118:47-55. 2006..CONCLUSIONS: Bedside EEG measures in term-born encephalopathic infants are related to the severity of cerebral injury as defined by qualitative MRI. A minimum amplitude of <4 microV appears useful in predicting outcome... - Preterm infant hippocampal volumes correlate with later working memory deficitsMiriam H Beauchamp
Murdoch Childrens Research Institute, The University of Melbourne, Melbourne, Vic, Australia
Brain 131:2986-94. 2008..Preterm children appear to have altered hippocampal volumes by discharge from hospital which may have a lasting impact on working memory function... - Predicting motor development in very preterm infants at 12 months' corrected age: the role of qualitative magnetic resonance imaging and general movements assessmentsAlicia J Spittle
Victorian Infant Brain Studies, Murdoch Children s Research Institute, 2nd Floor, Royal Children s Hospital, Flemington Road, Parkville 3052, Melbourne, Australia
Pediatrics 123:512-7. 2009.... - Cerebral injury in association with profound iatrogenic hyperglycemia in a neonateDaryl Efron
Department of Paediatrics, University of Melbourne, Royal Children's Hospital, Melbourne, Australia
Eur J Paediatr Neurol 7:167-71. 2003.... - Improving the outcome of infants born at <30 weeks' gestation--a randomized controlled trial of preventative care at homeAlicia J Spittle
Physiotherapy, School of Health Sciences, University of Melbourne, 200 Berkley Street, Parkville, Victoria 3052, Australia
BMC Pediatr 9:73. 2009..These interventions should be multi-faceted and include modules for caregivers given their high rates of mental health problems... - Reduced occipital regional volumes at term predict impaired visual function in early childhood in very low birth weight infantsDivyen K Shah
Department of Neonatal Neurology, Royal Children's Hospital, Murdoch Children's Research Institute, Melbourne, Australia
Invest Ophthalmol Vis Sci 47:3366-73. 2006..These findings assist in understanding the neuroanatomic correlates of later visual difficulties experienced by infants born prematurely... - Perinatal risk factors altering regional brain structure in the preterm infantDeanne K Thompson
Howard Florey Institute, University of Melbourne, Melbourne, Australia
Brain 130:667-77. 2007..These findings add to our understanding of the potential pathways leading to altered brain structure and outcome in the preterm infant... - Markers of oxidative injury in the cerebrospinal fluid of a premature infant with meningitis and periventricular leukomalaciaTerrie Inder
Murdoch Children's Research Institute and Howard Florey Institute, Royal Women's Hospital, Melbourne, Australia
J Pediatr 140:617-21. 2002..This case report is the first to demonstrate a marked elevation in the levels of lipid and protein oxidative products in the cerebrospinal fluid during the evolution of periventricular leukomalacia in a premature infant with meningitis... - White matter injury in the premature infant: a comparison between serial cranial sonographic and MR findings at termTerrie E Inder
Murdoch Children's Research Institute, Melbourne, Australia
AJNR Am J Neuroradiol 24:805-9. 2003..This deficiency of neonatal cranial US is important, because noncystic WM injury is considerably more common than cystic WM injury... - Parental mental health and early social-emotional development of children born very pretermKarli Treyvaud
Murdoch Childrens Research Institute, Royal Children s Hospital, Flemington Road, Parkville, Victoria, 3052, Australia
J Pediatr Psychol 35:768-77. 2010..The aims of this study were to describe the mental health of parents of children born very preterm and examine relations between parental mental health and early social-emotional development in very preterm and term born children... - Neurobehavior at term and white and gray matter abnormalities in very preterm infantsNisha C Brown
Victorian Infant Brain Studies, Murdoch Children s Research Institute, Melbourne, Australia
J Pediatr 155:32-8, 38.e1. 2009..To examine the relationship between very preterm infant neurobehavior at term and concurrent magnetic resonance-defined cerebral abnormalities... - Inhaled nitric oxide: effects on cerebral growth and injury in a baboon model of premature deliverySandra M Rees
Department of Anatomy and Cell Biology, University of Melbourne, Parkville, Victoria, 3010, Australia
Pediatr Res 61:552-8. 2007..Overall, iNO did not alter the extent of brain damage but did result in the presence of hematomas. These results do not confirm any protective or major injurious effect of nitric oxide therapy on the developing brain... - Parenting behavior is associated with the early neurobehavioral development of very preterm childrenKarli Treyvaud
Critical Care and Neurosciences, Murdoch Childrens Research Institute, Victoria, Australia
Pediatrics 123:555-61. 2009..The aim of this study was to assess the relationship between parenting behavior, parent-child synchrony, and neurobehavioral development in very preterm children at 24 months of age... - Reduced cerebellar diameter in very preterm infants with abnormal general movementsAlicia J Spittle
Murdoch Childrens Research Institute, Victoria, Australia
Early Hum Dev 86:1-5. 2010..However, other structural correlates of abnormal GMs have not been defined... - Apparent diffusion coefficient in the posterior limb of the internal capsule predicts outcome after perinatal asphyxiaRod W Hunt
Department of Neonatal Neurology, Royal Children's Hospital, Murdoch Children's Research Institute, University of Melbourne, Melbourne, Australia
Pediatrics 114:999-1003. 2004..60). CONCLUSION: The ADC value in the PLIC is an indicator of ischemic injury and may be of use as an objective prognostic marker for infants with HIE... - Reduction in cerebellar volumes in preterm infants: relationship to white matter injury and neurodevelopment at two years of ageDivyen K Shah
Victoria Infant Brain Study Group, Murdoch Children's Research Institute, Melbourne, Victoria, Australia
Pediatr Res 60:97-102. 2006..In conclusion, we found no evidence for a primary impairment in cerebellar development in relation to prematurity, although there was evidence for a secondary effect of cerebral WMI on cerebellar development independent of immaturity... - The relationship of CSF and plasma cytokine levels to cerebral white matter injury in the premature newbornVanessa J Ellison
Neonatal Medicine, Royal Women's Hospital, Melbourne, Victoria, Australia
Pediatr Res 57:282-6. 2005..Plasma cytokine concentrations may not reflect CSF cytokine levels or inflammatory events within the brain. Elevated CSF levels of cytokines in infants with white matter injury suggest an altered inflammatory balance... - Lowered electroencephalographic spectral edge frequency predicts the presence of cerebral white matter injury in premature infantsTerrie E Inder
Murdoch Children s Research Institute and Royal Women s and Royal Children s Hospital, Melbourne, Australia
Pediatrics 111:27-33. 2003..The critical measurement used, suggested largely by previous studies in animal models, was the spectral edge frequency (SEF), calculated here as the frequency below which 90% of the power in the EEG exists... - Defining the nature of the cerebral abnormalities in the premature infant: a qualitative magnetic resonance imaging studyTerrie E Inder
Murdoch Children s Research Institute, University of Melbourne, Royal Women s Hospital, Melbourne, Australia
J Pediatr 143:171-9. 2003..Perinatal factors were then related to the presence and severity of magnetic resonance imaging (MRI) abnormalities... - MR-determined hippocampal asymmetry in full-term and preterm neonatesDeanne K Thompson
Neuroimaging and Neuroinformatics, Howard Florey Institute, University of Melbourne, Victoria, Australia
Hippocampus 19:118-23. 2009..This study may suggest that hippocampal asymmetry develops in utero and is maintained into adulthood in infants with a normal neurological course... - Developmental and neuropathological consequences of ductal ligation in the preterm baboonMichelle Loeliger
Department of Anatomy and Cell Biology, University of Melbourne, Parkville, Victoria 3010, Australia
Pediatr Res 65:209-14. 2009..Surgical ligation of the PDA does not increase the incidence of brain injury and may be beneficial if the PDA is contributing to persistent pulmonary and hemodynamic instability... - Head growth in preterm infants: correlation with magnetic resonance imaging and neurodevelopmental outcomeJeanie L Y Cheong
Royal Women s Hospital, Department of Neonatal Services, 132 Grattan St, Carlton 3053, Melbourne, Australia
Pediatrics 121:e1534-40. 2008..The purpose of this work was to establish the relationship between head circumference with brain MRI at term-equivalent age and to relate head circumference with neurodevelopmental outcome at 2 years... - Insights into the pathogenesis of cerebral lesions in incontinentia pigmentiSabine J Hennel
Department of Pediatrics, Murdoch Children's Research Institute and Howard Florey Institute, and Royal Women's and Royal Children's Hospital, Parkville, Melbourne, Vic, Australia
Pediatr Neurol 29:148-50. 2003..This report adds important insights into the nature and timing of cerebral lesions in incontinentia pigmenti... - Magnetic resonance demonstration in the newborn of generalized cerebral venous dilation with spontaneous resolutionRod W Hunt
Department of Neonatal Neurology, Level 2, Royal Children's Hospital, Flemington Road, Parkville, Victoria 3052, Australia
Eur J Paediatr Neurol 6:289-92. 2002..Complete resolution of the venous dilation and the lack of definable parenchymal injury suggest a good prognosis for this disorder... - Monitoring the neonatal brain: a survey of current practice among Australian and New Zealand neonatologistsPeter M Filan
Victorian Infant Brain Study Group, Murdoch Children s Research Institute, Melbourne, Victoria, Australia
J Paediatr Child Health 43:557-9. 2007..The aims of this study were (i) to document the current practice among Australian and New Zealand neonatologists; and (ii) to identify the factors that influence local practice... - Caffeine and brain development in very preterm infantsLex W Doyle
Royal Women s Hospital, University of Melbourne, Parkville, Victoria, Australia
Ann Neurol 68:734-42. 2010..The objective of this study was to assess whether caffeine influenced brain macro- or microstructural development in preterm infants... - Neurodevelopmental impact of low-grade intraventricular hemorrhage in very preterm infantsTerrie E Inder
J Pediatr 149:152-4. 2006 - Imaging perinatal brain injury in premature infantsJeffrey J Neil
Department of Neurology, Washington University School of Medicine, St Louis, MO, USA
Semin Perinatol 28:433-43. 2004..Current guidelines regarding the application of these neuroimaging methods to the premature infant are discussed... - Regional brain development in serial magnetic resonance imaging of low-risk preterm infantsAndrea U J Mewes
Department of Radiology, Brigham and Women s Hospital, Harvard Medical School, 75 Francis St, Boston, Massachusetts 02115, USA
Pediatrics 118:23-33. 2006..In this study, we investigated serial MRI of low-risk preterm infants with the aim to identify regions of altered brain development... - Diffusion MR imaging characteristics of the developing primate brainChristopher D Kroenke
Department of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA
Neuroimage 25:1205-13. 2005..These changes closely parallel those of live, developing human brain. The information obtained from this primate model of cerebral microstructure is directly applicable to studies of human development... - Object working memory deficits predicted by early brain injury and development in the preterm infantLianne J Woodward
Child Development Research Group, University of Canterbury and Van der Veer Institute for Parkinson s and Brain Research, Christchurch, New Zealand
Brain 128:2578-87. 2005..These findings add to our understanding of the neuropathological pathways associated with later executive dysfunction in the very preterm infant... - Developmental changes and injury induced disruption of the radial organization of the cortex in the immature rat brain revealed by in vivo diffusion tensor MRIStephane V Sizonenko
Child Development Unit, Department of Paediatrics, School of Medicine, University of Geneva, Switzerland
Cereb Cortex 17:2609-17. 2007..Thus, the combined use of in vivo DTI and histopathology can assist in delineating normal developmental changes and postinjury modifications in the immature rodent brain... - Growth rate of corpus callosum in very premature infantsNigel G Anderson
Department of Radiology, Christchurch Hospital, Christchurch, New Zealand
AJNR Am J Neuroradiol 26:2685-90. 2005..Those with poorer neurodevelopmental outcomes have a shorter CC at term equivalency. The CC grows at a much lower rate postnatally than in utero among very premature infants... - Application of magnetic resonance imaging in animal models of perinatal hypoxic-ischemic cerebral injuryGregory A Lodygensky
Departments of Pediatrics, Washington University School of Medicine, St Louis, MO, USA
Int J Dev Neurosci 26:13-25. 2008..The MR findings are then related to histopathology and, in a few cases, behavioral evaluations. There is also a growing number of studies utilizing MRI in evaluating the efficacy of neuroprotective treatments, such as hypothermia... - Detection of impaired growth of the corpus callosum in premature infantsNigel G Anderson
Department of Radiology, Christchurch Hospital, Riccarton Avenue, Christchurch 8001, New Zealand
Pediatrics 118:951-60. 2006..The aim of this study was to assess the impact of preterm birth on the serial growth of the corpus callosum and how soon it could be detected after birth with cranial ultrasound... - Neonatal MRI to predict neurodevelopmental outcomes in preterm infantsLianne J Woodward
Canterbury Child Development Research Group, Department of Psychology, University of Canterbury and the Van der Veer Institute for Parkinson s and Brain Research, Christchurch, New Zealand
N Engl J Med 355:685-94. 2006..Very preterm infants are at high risk for adverse neurodevelopmental outcomes. Magnetic resonance imaging (MRI) has been proposed as a means of predicting neurodevelopmental outcomes in this population... - Transport, monitoring, and successful brain MR imaging in unsedated neonatesAmit M Mathur
Department of Pediatrics and Newborn Medicine, St Louis Children s Hospital at the Washington University School of Medicine, One Children s Place, St Louis, MO 63005, USA
Pediatr Radiol 38:260-4. 2008..We present our own institutional experience and guidelines used to optimize the performance of cerebral MR examinations in neonates without sedation or anesthesia... - Modeling water diffusion anisotropy within fixed newborn primate brain using Bayesian probability theoryChristopher D Kroenke
Department of Radiology, Washington University, St Louis, Missouri 63110, USA
Magn Reson Med 55:187-97. 2006..Intuitively, the positive offset can be thought of as spins that are sufficiently restricted to appear immobile over the sampled range of b-values... - Health service utilisation of a regional cohort of very preterm infants over the first 2 years of lifeDiane Gray
Neonatal Service, Christchurch Women's Hospital, and Canterbury Child Development Research Group, University of Canterbury, Christchurch, New Zealand
J Paediatr Child Health 42:377-83. 2006..These findings highlight that very preterm birth is associated with ongoing health morbidity... - The effect of gestational age and labour on markers of lipid and protein oxidation in cord plasmaTessa J Mocatta
Department of Pathology, Christchurch School of Medicine and Health Sciences, P.O. Box 4345, Christchurch, New Zealand
Free Radic Res 38:185-91. 2004..More information is needed on the source and fate of these and other biomarkers before drawing strong conclusions on how they reflect oxidative stress in this and other clinical situations... - Neonatal seizures: have we got the treatment right?Rod W Hunt
J Paediatr Child Health 41:311-2. 2005 - Can neurobehavioral examination predict the presence of cerebral injury in the very low birth weight infant?Lianne J Woodward
University of Canterbury and Christchurch School of Medicine, Christchurch, New Zealand
J Dev Behav Pediatr 25:326-34. 2004..Implications of these findings for the neurological evaluation of the very low birth weight infant are discussed... - Displacement of brain regions in preterm infants with non-synostotic dolichocephaly investigated by MRIAndrea U J Mewes
Department of Radiology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
Neuroimage 36:1074-85. 2007..We concluded that the validity of a Talairach parcellation scheme is compromised and may lead to a miscalculation of regional brain volumes and inconsistent parcel contents when comparing infant populations with divergent head shapes... - Seizure detection algorithm for neonates based on wave-sequence analysisMichael A Navakatikyan
BrainZ Instruments Ltd, 25 Carbine Road, Mt Wellington, P O Box 51078 Pakuranga, Auckland 1730, New Zealand
Clin Neurophysiol 117:1190-203. 2006..The description and evaluation of the performance of a new real-time seizure detection algorithm in the newborn infant... - Amplitude-integrated electroencephalography in the newborn: a valuable toolDivyen K Shah
Department of Pediatrics, Washington University, St Louis, MO 63110, USA
Pediatrics 122:863-5. 2008 - A limited range of measures of 2-D ultrasound correlate with 3-D MRI cerebral volumes in the premature infant at termNigel G Anderson
Radiology Department, Christchurch Women s Hospital, Christchurch, New Zealand
Ultrasound Med Biol 30:11-8. 2004.... - Adverse neurodevelopment in preterm infants with postnatal sepsis or necrotizing enterocolitis is mediated by white matter abnormalities on magnetic resonance imaging at termDivyen K Shah
Department of Pediatrics, Washington University, St Louis, MO 63105, USA
J Pediatr 153:170-5, 175.e1. 2008..To test the hypothesis that the impact of postnatal sepsis/necrotizing enterocolitis (NEC) on neurodevelopment may be mediated by white matter abnormality (WMA), which can be demonstrated with magnetic resonance imaging (MRI)... - Microstructural changes of the baboon cerebral cortex during gestational development reflected in magnetic resonance imaging diffusion anisotropyChristopher D Kroenke
Oregon National Primate Research Center, and Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, Oregon 97239, USA
J Neurosci 27:12506-15. 2007..The approach presented here can be applied in vivo to the study of normal brain development and its disruption in human infants and experimental animal models... - Executive functioning in preschool children born very preterm: relationship with early white matter pathologyJamie O Edgin
Department of Psychology, University of Canterbury and Van der Veer Institute for Parkinson s and Brain Research, Christchurch, New Zealand
J Int Neuropsychol Soc 14:90-101. 2008..These findings support the presence of early and persistent executive difficulties in preschool children born very preterm, and highlight the importance of white matter pathology in the development of executive impairments... - Accuracy of bedside electroencephalographic monitoring in comparison with simultaneous continuous conventional electroencephalography for seizure detection in term infantsDivyen K Shah
Washington University, Department of Pediatrics, One Children s Place, St Louis, MO 63110, USA
Pediatrics 121:1146-54. 2008....