Ralf G Heine

Summary

Affiliation: Royal Children's Hospital
Country: Australia

Publications

  1. ncbi request reprint IgE food sensitization in infants with eczema attending a dermatology department
    David J Hill
    Murdoch Children s Research Institute, Melbourne, Australia
    J Pediatr 151:359-63. 2007
  2. doi request reprint Dietary approaches to the prevention of food allergy
    Ralf G Heine
    Department of Allergy and Immunology, Royal Children s Hospital, Department of Paediatrics, University of Melbourne, Parkville, VIC 3052, Australia
    Curr Opin Clin Nutr Metab Care 11:320-8. 2008
  3. doi request reprint Allergic gastrointestinal motility disorders in infancy and early childhood
    Ralf G Heine
    Department of Gastroenterology and Clinical Nutrition Royal Children s Hospital, University of Melbourne, Murdoch Childrens Research Institute, Melbourne, Victoria, Australia
    Pediatr Allergy Immunol 19:383-91. 2008
  4. doi request reprint Eosinophilic esophagitis: example of an emerging allergic manifestation?
    Ralf G Heine
    Department of Gastroenterology and Clinical Nutrition, Royal Children s Hospital, Parkville, Melbourne, Victoria, Australia
    Nestle Nutr Workshop Ser Pediatr Program 64:105-15; discussion 116-20, 251-7. 2009
  5. ncbi request reprint Gastroesophageal reflux disease, colic and constipation in infants with food allergy
    Ralf G Heine
    Department of Allergy, Royal Children s Hospital, Parkville, Victoria, Australia
    Curr Opin Allergy Clin Immunol 6:220-5. 2006
  6. ncbi request reprint The diagnosis and management of egg allergy
    Ralf G Heine
    Department of Allergy, Royal Children s Hospital, Flemington Road, Parkville, Victoria 3052, Australia
    Curr Allergy Asthma Rep 6:145-52. 2006
  7. ncbi request reprint Clinical predictors of pathological gastro-oesophageal reflux in infants with persistent distress
    Ralf G Heine
    Department of Gastroenterology and Clinical Nutrition, Royal Children s Hospital, Melbourne, Australia
    J Paediatr Child Health 42:134-9. 2006
  8. ncbi request reprint Pathophysiology, diagnosis and treatment of food protein-induced gastrointestinal diseases
    Ralf G Heine
    Department of Allergy, Royal Children s Hospital, and Department of Paediatrics, University of Melbourne, Victoria, Australia
    Curr Opin Allergy Clin Immunol 4:221-9. 2004
  9. ncbi request reprint Effect of a low-allergen maternal diet on colic among breastfed infants: a randomized, controlled trial
    David J Hill
    Department of Allergy, Royal Children s Hospital, Melbourne, Australia
    Pediatrics 116:e709-15. 2005
  10. doi request reprint Early clinical predictors of remission of peanut allergy in children
    Marco H K Ho
    Department of Allergy and Immunology, Royal Children s Hospital, Melbourne, Australia
    J Allergy Clin Immunol 121:731-6. 2008

Collaborators

Detail Information

Publications39

  1. ncbi request reprint IgE food sensitization in infants with eczema attending a dermatology department
    David J Hill
    Murdoch Children s Research Institute, Melbourne, Australia
    J Pediatr 151:359-63. 2007
    ....
  2. doi request reprint Dietary approaches to the prevention of food allergy
    Ralf G Heine
    Department of Allergy and Immunology, Royal Children s Hospital, Department of Paediatrics, University of Melbourne, Parkville, VIC 3052, Australia
    Curr Opin Clin Nutr Metab Care 11:320-8. 2008
    ..Although some preventive dietary interventions have entered common practice, the level of evidence underpinning these strategies varies...
  3. doi request reprint Allergic gastrointestinal motility disorders in infancy and early childhood
    Ralf G Heine
    Department of Gastroenterology and Clinical Nutrition Royal Children s Hospital, University of Melbourne, Murdoch Childrens Research Institute, Melbourne, Victoria, Australia
    Pediatr Allergy Immunol 19:383-91. 2008
    ..The following article will present three instructive cases followed by discussion of the clinical presentation, diagnosis, treatment and natural history of food allergic motility disorders in infancy and early childhood...
  4. doi request reprint Eosinophilic esophagitis: example of an emerging allergic manifestation?
    Ralf G Heine
    Department of Gastroenterology and Clinical Nutrition, Royal Children s Hospital, Parkville, Melbourne, Victoria, Australia
    Nestle Nutr Workshop Ser Pediatr Program 64:105-15; discussion 116-20, 251-7. 2009
    ..These patients may respond to swallowed corticosteroid aerosols or other immune-modulating drugs. Further prospective clinical trials are needed to outline the most effective long-term treatment of EE...
  5. ncbi request reprint Gastroesophageal reflux disease, colic and constipation in infants with food allergy
    Ralf G Heine
    Department of Allergy, Royal Children s Hospital, Parkville, Victoria, Australia
    Curr Opin Allergy Clin Immunol 6:220-5. 2006
    ..This review assesses the role of food allergy in the pathophysiology of gastroesophageal reflux disease, colic and constipation in infancy...
  6. ncbi request reprint The diagnosis and management of egg allergy
    Ralf G Heine
    Department of Allergy, Royal Children s Hospital, Flemington Road, Parkville, Victoria 3052, Australia
    Curr Allergy Asthma Rep 6:145-52. 2006
    ..The treatment of egg allergy consists of dietary elimination, or a maternal elimination diet in breast-fed infants. Approximately two thirds of infants with egg allergy will become tolerant by 7 years of age...
  7. ncbi request reprint Clinical predictors of pathological gastro-oesophageal reflux in infants with persistent distress
    Ralf G Heine
    Department of Gastroenterology and Clinical Nutrition, Royal Children s Hospital, Melbourne, Australia
    J Paediatr Child Health 42:134-9. 2006
    ..Gastro-oesophageal reflux (GOR) is common in infants with persistent crying. Empirical treatment with antireflux medications is common practice, although on clinical grounds it may be difficult to determine whether GOR is abnormal...
  8. ncbi request reprint Pathophysiology, diagnosis and treatment of food protein-induced gastrointestinal diseases
    Ralf G Heine
    Department of Allergy, Royal Children s Hospital, and Department of Paediatrics, University of Melbourne, Victoria, Australia
    Curr Opin Allergy Clin Immunol 4:221-9. 2004
    ..Although our general understanding of food hypersensitivity has improved in recent years, gastrointestinal food protein-induced diseases still pose diagnostic and therapeutic dilemmas...
  9. ncbi request reprint Effect of a low-allergen maternal diet on colic among breastfed infants: a randomized, controlled trial
    David J Hill
    Department of Allergy, Royal Children s Hospital, Melbourne, Australia
    Pediatrics 116:e709-15. 2005
    ..There is controversy regarding whether hypersensitivity to food proteins contributes to colic among breastfed infants...
  10. doi request reprint Early clinical predictors of remission of peanut allergy in children
    Marco H K Ho
    Department of Allergy and Immunology, Royal Children s Hospital, Melbourne, Australia
    J Allergy Clin Immunol 121:731-6. 2008
    ..Understanding predictors of clinical remission would assist in clinical management of peanut allergy...
  11. doi request reprint Oesophagitis in children: reflux or allergy?
    Kerryn Ireland-Jenkin
    Department of Anatomical Pathology, Royal Children s Hospital, Melbourne, Victoria, Australia
    Pathology 40:188-95. 2008
    ..Long-term uncontrolled oesophageal eosinophilic inflammation may lead to progressive subepithelial fibrosis, potentially resulting in strictures or oesophageal narrowing...
  12. ncbi request reprint Treating infant colic with the probiotic Lactobacillus reuteri: double blind, placebo controlled randomised trial
    Valerie Sung
    Royal Children s Hospital, Parkville, Victoria, Australia
    BMJ 348:g2107. 2014
    ..To determine whether the probiotic Lactobacillus reuteri DSM 17938 reduces crying or fussing in a broad community based sample of breastfed infants and formula fed infants with colic aged less than 3 months...
  13. doi request reprint Egg allergy in childhood: an update
    Dean Tey
    Department of Allergy and Immunology, Royal Children s Hospital, Melbourne, Australia
    Curr Opin Allergy Clin Immunol 9:244-50. 2009
    ..In this article, we review the recent literature regarding the immunology, clinical presentation, diagnosis, management and natural history of egg allergy...
  14. doi request reprint Management of cow's milk protein allergy in infants and young children: an expert panel perspective
    Katrina J Allen
    Murdoch Childrens Research Institute, Melbourne, Vic, Australia
    J Paediatr Child Health 45:481-6. 2009
    ....
  15. ncbi request reprint 4. Food allergy in childhood
    Katrina J Allen
    Department of Allergy and Immunology, Royal Children s Hospital, Melbourne, Victoria, Australia
    Med J Aust 185:394-400. 2006
    ..Children often develop tolerance to cows milk, egg, soy and wheat by school age, whereas allergies to nuts and shellfish are more likely to be lifelong...
  16. ncbi request reprint Effect of antireflux medication, placebo and infant mental health intervention on persistent crying: a randomized clinical trial
    Brigid Jordan
    Mental Health Service, Royal Children s Hospital, Melbourne, Victoria, Australia
    J Paediatr Child Health 42:49-58. 2006
    ..To assess the effect of medical antireflux treatment, and of an infant mental health consultation (IMHC), on persistent crying in infants and maternal distress...
  17. ncbi request reprint The diagnostic value of skin prick testing in children with food allergy
    David J Hill
    Department of Allergy, Royal Children s Hospital, Flemington Road, Parkville, Victoria 3052, Australia
    Pediatr Allergy Immunol 15:435-41. 2004
    ..0001) and peanut (p < 0.0001). Further studies are required to define age-specific diagnostic IgE antibody and SPT cut-off levels use in infants under 2 yr of age with suspected food allergies...
  18. doi request reprint Cost-effectiveness of partially-hydrolyzed formula for prevention of atopic dermatitis in Australia
    John Su
    Department of Dermatology, Royal Children s Hospital, University of Melbourne, Melbourne, Australia Monash University, Melbourne, Australia
    J Med Econ 15:1064-77. 2012
    ..To perform an economic evaluation of a specific brand of partially hydrolyzed infant formula (PHF-W) in the prevention of atopic dermatitis (AD) among Australian infants...
  19. doi request reprint Eosinophilic esophagitis: trials and tribulations
    Katrina J Allen
    Department of Gastroenterology and Clinical Nutrition, Royal Children s Hospital, Melbourne, Australia
    J Clin Gastroenterol 45:574-82. 2011
    ..This article aims to discuss the complex issues of the diagnosis and long-term management that confront clinicians who care for children with EE...
  20. ncbi request reprint Factors affecting clinical outcome in gastrostomy-fed children with cystic fibrosis
    Mark R Oliver
    Department of Gastroenterology and Nutrition, Royal Children s Hospital, Melbourne, Australia
    Pediatr Pulmonol 37:324-9. 2004
    ..32 +/- 0.26 vs. 0.03 +/- 0.39; P = 0.03). In conclusion, the presence of advanced lung disease, GER, and female gender were factors associated with a poor clinical outcome after gastrostomy placement...
  21. ncbi request reprint Complications associated with endoscopic removal of percutaneous endoscopic gastrostomy (PEG) tubes in children
    Greta M Palmer
    Department of Anaesthesia and Pain Management, Royal Children s Hospital, Melbourne, Australia
    J Pediatr Gastroenterol Nutr 42:443-5. 2006
  22. pmc Probiotics to improve outcomes of colic in the community: protocol for the Baby Biotics randomised controlled trial
    Valerie Sung
    Royal Children s Hospital, Parkville, Australia
    BMC Pediatr 12:135. 2012
    ..The Baby Biotics trial aims to determine whether the probiotic Lactobacillus reuteri DSM 17938 is effective in reducing crying in infants less than three months old (<13.0 weeks) with infant colic when compared to placebo...
  23. doi request reprint Health and well-being in school-age children following persistent crying in infancy
    Mary Brown
    The University of Melbourne, Melbourne, Victoria, Australia
    J Paediatr Child Health 45:254-62. 2009
    ..To examine the physical and mental health outcomes at school-age of a cohort of children who participated in a randomised clinical trial of treatments for persistent crying in infancy...
  24. doi request reprint Randomized clinical trial of rapid versus 24-hour rehydration for children with acute gastroenteritis
    Colin V E Powell
    Departments of aEmergency Medicine, Royal Children s Hospital, Melbourne, Australia
    Pediatrics 128:e771-8. 2011
    ..To compare the efficacy of 2 nasogastric rehydration regimens for children with acute viral gastroenteritis...
  25. ncbi request reprint Cow's milk allergy in infancy
    Ralf G Heine
    Department of Allergy, Royal Children s Hospital, Parkville, Victoria, Australia
    Curr Opin Allergy Clin Immunol 2:217-25. 2002
    ..The treatment of cow's milk allergy relies on allergen avoidance and hypoallergenic formulae, or maternal elimination diets in breast-fed infants...
  26. ncbi request reprint Esophagitis in distressed infants: poor diagnostic agreement between esophageal pH monitoring and histopathologic findings
    Ralf G Heine
    Department of Gastroenterology, Royal Children s Hospital, Melbourne, Australia
    J Pediatr 140:14-9. 2002
    ..Our purpose was to study the relation between gastroesophageal reflux (GER) and esophagitis in infants with persistent distress...
  27. ncbi request reprint Upright positive expiratory pressure therapy and exercise: effects on gastroesophageal reflux in COPD and bronchiectasis
    Annemarie L Lee
    Department of Physiotherapy, Melbourne School of Health Sciences, The University of Melbourne, Melbourne, Australia
    Respir Care 57:1460-7. 2012
    ..This study aimed to determine if positive expiratory pressure (PEP) therapy and standardized exercise tasks were associated with increased gastroesophageal reflux...
  28. ncbi request reprint Body composition of children with chronic and end-stage renal failure
    Andreas Nydegger
    Department of Gastroenterology, Royal Children s Hospital, Parkville, Victoria, Australia
    J Paediatr Child Health 43:740-5. 2007
    ..Although the aetiology of malnutrition is multifactorial, descriptive information on body composition may guide nutritional interventions aimed at optimising nutritional status...
  29. ncbi request reprint Macrogol 3350 plus electrolytes for chronic constipation in children: a single-centre, open-label study
    Winita Hardikar
    Department of Gastroenterology and Clinical Nutrition, Royal Children s Hospital, Parkville, Victoria, Australia
    J Paediatr Child Health 43:527-31. 2007
    ..This open-label, non-randomised study aimed to evaluate the safety and efficacy of this preparation in the treatment of chronic constipation in children...
  30. ncbi request reprint Changing incidence of acute pancreatitis: 10-year experience at the Royal Children's Hospital, Melbourne
    Andreas Nydegger
    Department of Gastroenterology and Clinical Nutrition, Royal Children s Hospital, Parkville, Melbourne, Victoria, Australia
    J Gastroenterol Hepatol 22:1313-6. 2007
    ..The aim of this study was to assess the incidence and etiology of acute pancreatitis at a major pediatric referral center in Australia...
  31. doi request reprint Emerging management concepts for eosinophilic esophagitis in children
    Ralf G Heine
    Department of Gastroenterology and Clinical Nutrition and Royal Children s Hospital, Melbourne, Australia
    J Gastroenterol Hepatol 26:1106-13. 2011
    ..This paper aims to discuss the various strategies currently available to clinicians in the management of EoE and highlights gaps in the current evidence base that urgently require further research...
  32. doi request reprint Tolerability and safety of olive oil-based lipid emulsion in critically ill neonates: a blinded randomized trial
    Annette N Webb
    Department of Gastroenterology and Clinical Nutrition, The Royal Children s Hospital, Melbourne, Victoria, Australia
    Nutrition 24:1057-64. 2008
    ..We assessed the safety and tolerability of an olive oil-based lipid emulsion compared with a soybean-based lipid emulsion in critically ill neonates...
  33. ncbi request reprint Chest physiotherapy in infants with cystic fibrosis: to tip or not? A five-year study
    Brenda M Button
    Department of Physiotherapy, Royal Children s Hospital, Melbourne, Australia
    Pediatr Pulmonol 35:208-13. 2003
    ..03). Forced vital capacity and forced expired volume in 1 sec (FEV(1)) at 5-6 years was lower for SPT than for MPT (P < 0.05). In conclusion, MPT was associated with fewer respiratory complications than SPT in infants with CF...
  34. ncbi request reprint Proposal for a standardized interpretation of the atopy patch test in children with atopic dermatitis and suspected food allergy
    Ralf G Heine
    Department of Pediatric Pneumology and Immunology, Children s Hospital Charité, Humboldt University, Berlin, Germany
    Pediatr Allergy Immunol 17:213-7. 2006
    ..Presence of both induration and of at least seven papules at 72 h were the APT skin signs with the greatest diagnostic accuracy for food allergy in children with AD...
  35. doi request reprint The importance of early complementary feeding in the development of oral tolerance: concerns and controversies
    Susan L Prescott
    School of Paediatrics and Child Health Research, University of Western Australia, Perth, WA, Australia
    Pediatr Allergy Immunol 19:375-80. 2008
    ..It will also examine the growing case for introducing complementary foods from around 4 months of age and maintaining breastfeeding during this early feeding period, for at least 6 months if possible...
  36. ncbi request reprint Eosinophilic oesophagitis
    Alyson Kakakios
    Department of Immunology and Infectious Diseases, The Children s Hospital at Westmead, Sydney, NSW, Australia
    Med J Aust 185:401. 2006
  37. ncbi request reprint Primary prevention of atopic dermatitis in breast-fed infants: what is the evidence?
    Ralf G Heine
    J Pediatr 144:564-7. 2004
  38. doi request reprint Eosinophilic esophagitis in children with celiac disease: new diagnostic and therapeutic dilemmas
    Ralf G Heine
    J Gastroenterol Hepatol 23:993-4. 2008
  39. ncbi request reprint Diagnostic accuracy of skin prick testing in children with tree nut allergy
    Marco H K Ho
    J Allergy Clin Immunol 117:1506-8. 2006