J A Ellis

Summary

Affiliation: Royal Children's Hospital
Country: Australia

Publications

  1. pmc Androgen receptor copy number variation and androgenetic alopecia: a case-control study
    Joanna E Cobb
    Department of Physiology, University of Melbourne, Melbourne, Victoria, Australia
    PLoS ONE 4:e5081. 2009
  2. pmc Independent replication analysis of genetic loci with previous evidence of association with juvenile idiopathic arthritis
    Justine A Ellis
    Genes, Environment and Complex Disease, Murdoch Childrens Research Institute, 50 Flemington Rd, Parkville, Vic, 3052, Australia
    Pediatr Rheumatol Online J 11:12. 2013
  3. pmc CLARITY - ChiLdhood Arthritis Risk factor Identification sTudY
    Justine A Ellis
    Genes, Environment and Complex Disease, Murdoch Childrens Research Institute, Parkville, Vic, Australia
    Pediatr Rheumatol Online J 10:37. 2012
  4. pmc Genome-scale case-control analysis of CD4+ T-cell DNA methylation in juvenile idiopathic arthritis reveals potential targets involved in disease
    Justine A Ellis
    Genes, Environment and Complex Disease, Murdoch Childrens Research Institute, 50 Flemington Rd, Parkville, Vic, Australia
    Clin Epigenetics 4:20. 2012
  5. pmc APOE genotype and cardio-respiratory fitness interact to determine adiposity in 8-year-old children from the Tasmanian Infant Health Survey
    Justine A Ellis
    Environmental and Genetic Epidemiology Research, Murdoch Childrens Research Institute, Parkville, Australia
    PLoS ONE 6:e26679. 2011
  6. doi request reprint Male pattern baldness: current treatments, future prospects
    Justine A Ellis
    Department of Physiology, University of Melbourne, Victoria 3010, Australia
    Drug Discov Today 13:791-7. 2008
  7. doi request reprint A role for the DRD4 exon III VNTR in modifying the association between nicotine dependence and neuroticism
    J A Ellis
    Environmental and Genetic Epidemiology Research, Murdoch Childrens Research Institute, Royal Children s Hospital, Parkville, Victoria 3052, Australia
    Nicotine Tob Res 13:64-9. 2011
  8. doi request reprint Possible environmental determinants of juvenile idiopathic arthritis
    Justine A Ellis
    Murdoch Children s Research Institute, Royal Children s Hospital, Parkville, Victoria 3052, Australia
    Rheumatology (Oxford) 49:411-25. 2010
  9. doi request reprint Genes controlling postural changes in blood pressure: comprehensive association analysis of ATP-sensitive potassium channel genes KCNJ8 and ABCC9
    Justine A Ellis
    Department of Physiology, University of Melbourne, Melbourne, Victoria, Australia
    Physiol Genomics 40:184-8. 2010
  10. ncbi request reprint Sex, genes and blood pressure
    J A Ellis
    Department of Physiology, The University of Melbourne, Victoria, Australia
    Clin Exp Pharmacol Physiol 28:1053-5. 2001

Collaborators

Detail Information

Publications28

  1. pmc Androgen receptor copy number variation and androgenetic alopecia: a case-control study
    Joanna E Cobb
    Department of Physiology, University of Melbourne, Melbourne, Victoria, Australia
    PLoS ONE 4:e5081. 2009
    ..The aim of this preliminary case-control study was to determine if AR CNV is associated with AGA, with the hypothesis that CNV is the functional AR variant contributing to this condition...
  2. pmc Independent replication analysis of genetic loci with previous evidence of association with juvenile idiopathic arthritis
    Justine A Ellis
    Genes, Environment and Complex Disease, Murdoch Childrens Research Institute, 50 Flemington Rd, Parkville, Vic, 3052, Australia
    Pediatr Rheumatol Online J 11:12. 2013
    ....
  3. pmc CLARITY - ChiLdhood Arthritis Risk factor Identification sTudY
    Justine A Ellis
    Genes, Environment and Complex Disease, Murdoch Childrens Research Institute, Parkville, Vic, Australia
    Pediatr Rheumatol Online J 10:37. 2012
    ..abstract:..
  4. pmc Genome-scale case-control analysis of CD4+ T-cell DNA methylation in juvenile idiopathic arthritis reveals potential targets involved in disease
    Justine A Ellis
    Genes, Environment and Complex Disease, Murdoch Childrens Research Institute, 50 Flemington Rd, Parkville, Vic, Australia
    Clin Epigenetics 4:20. 2012
    ..abstract:..
  5. pmc APOE genotype and cardio-respiratory fitness interact to determine adiposity in 8-year-old children from the Tasmanian Infant Health Survey
    Justine A Ellis
    Environmental and Genetic Epidemiology Research, Murdoch Childrens Research Institute, Parkville, Australia
    PLoS ONE 6:e26679. 2011
    ..APOE4 and cardiorespitatory fitness could interact to influence child adiposity. In studies addressing the genetic determinants of childhood obesity, the context of child fitness should also be taken into account...
  6. doi request reprint Male pattern baldness: current treatments, future prospects
    Justine A Ellis
    Department of Physiology, University of Melbourne, Victoria 3010, Australia
    Drug Discov Today 13:791-7. 2008
    ..New treatments under development, and acceleration in our understanding of the underlying molecular genetic aetiology of this condition provide increased hope for future targeted treatment strategies...
  7. doi request reprint A role for the DRD4 exon III VNTR in modifying the association between nicotine dependence and neuroticism
    J A Ellis
    Environmental and Genetic Epidemiology Research, Murdoch Childrens Research Institute, Royal Children s Hospital, Parkville, Victoria 3052, Australia
    Nicotine Tob Res 13:64-9. 2011
    ....
  8. doi request reprint Possible environmental determinants of juvenile idiopathic arthritis
    Justine A Ellis
    Murdoch Children s Research Institute, Royal Children s Hospital, Parkville, Victoria 3052, Australia
    Rheumatology (Oxford) 49:411-25. 2010
    ..Finally, we discuss future directions including practical study designs to more comprehensively test hypotheses and provide new insight into this important area of research...
  9. doi request reprint Genes controlling postural changes in blood pressure: comprehensive association analysis of ATP-sensitive potassium channel genes KCNJ8 and ABCC9
    Justine A Ellis
    Department of Physiology, University of Melbourne, Melbourne, Victoria, Australia
    Physiol Genomics 40:184-8. 2010
    ..We conclude that sequence variants in KCNJ8 and ABCC9 are unlikely to contribute to variation in DeltaSBP. Other genes in the identified chromosome 12p region warrant investigation...
  10. ncbi request reprint Sex, genes and blood pressure
    J A Ellis
    Department of Physiology, The University of Melbourne, Victoria, Australia
    Clin Exp Pharmacol Physiol 28:1053-5. 2001
    ..Further genetic and physiological analyses will be required to confirm these observations and to determine the mechanisms of action and the nature of any interactions...
  11. ncbi request reprint Significant population variation in adult male height associated with the Y chromosome and the aromatase gene
    J A Ellis
    Department of Physiology, The University of Melbourne, Victoria 3010, Australia
    J Clin Endocrinol Metab 86:4147-50. 2001
    ..67-7.3) was detected (P = 0.004). These results suggest that in men, genetic variation in CYP19 and on the Y chromosome are involved in determining normal adult height, and that these loci may interact in an additive fashion...
  12. ncbi request reprint Polymorphism of the androgen receptor gene is associated with male pattern baldness
    J A Ellis
    Department of Physiology, The University of Melbourne, Victoria, Australia
    J Invest Dermatol 116:452-5. 2001
    ..Functional mutation in or near the androgen receptor gene may explain the reported high levels of expression of this gene in the balding scalp...
  13. ncbi request reprint Male pattern baldness is not associated with established cardiovascular risk factors in the general population
    J A Ellis
    Department of Physiology, The University of Melbourne, Victoria 3010, Australia
    Clin Sci (Lond) 100:401-4. 2001
    ..The lack of association between baldness and established coronary risk factors implies that baldness may predispose to coronary heart disease through novel mechanisms yet to be defined...
  14. pmc Interaction of Crohn's disease susceptibility genes in an Australian paediatric cohort
    Josef Wagner
    Enteric Virus Group, Murdoch Childrens Research Institute, Melbourne, Victoria, Australia
    PLoS ONE 5:e15376. 2010
    ..Our findings demonstrate that CD genetic susceptibility in paediatric patients presents as a complex interaction between numerous genes...
  15. doi request reprint Adiposity gain during childhood, ACE I/D polymorphisms and metabolic outcomes
    Anne Louise Ponsonby
    Murdoch Childrens Research Institute, Royal Children s Hospital, Melbourne, Victoria, Australia
    Obesity (Silver Spring) 16:2141-7. 2008
    ..Further work is required to confirm and extend these findings...
  16. pmc Effects of NRG1 and DAOA genetic variation on transition to psychosis in individuals at ultra-high risk for psychosis
    C A Bousman
    Melbourne Brain Centre, Department of Psychiatry, The University of Melbourne, Parkville, Vic, Australia
    Transl Psychiatry 3:e251. 2013
    ..None of the assessed DAOA htSNPs were associated with transition. Our findings suggest NRG1 genetic variation may improve our ability to identify UHR individuals at risk for transition to psychosis...
  17. ncbi request reprint Genetic analysis of male pattern baldness and the 5alpha-reductase genes
    J A Ellis
    Department of Physiology, The University of Melbourne, Parkville, Victoria, Australia
    J Invest Dermatol 110:849-53. 1998
    ..The relatively strong concordance for baldness between fathers and sons in this study was not consistent with a simple Mendelian autosomal dominant inheritance. A polygenic etiology should be considered...
  18. ncbi request reprint Sex-dependent association of blood pressure with oestrogen receptor genes ERalpha and ERbeta
    Justine A Ellis
    Department of Physiology, The University of Melbourne, Victoria 3010, Australia
    J Hypertens 22:1127-31. 2004
    ..The existence of such sex steroid-related genes may help to explain the observed sex differences in blood pressure...
  19. ncbi request reprint Selective genotyping reveals association between the epithelial sodium channel gamma-subunit and systolic blood pressure
    Cara J Büsst
    Department of Physiology, University of Melbourne, Parkville, Victoria, Australia
    Hypertension 50:672-8. 2007
    ..These findings identify relatively common polymorphisms in the SCNN1G gene that are associated with high systolic blood pressure in the general Australian white population...
  20. ncbi request reprint Baldness and the androgen receptor: the AR polyglycine repeat polymorphism does not confer susceptibility to androgenetic alopecia
    Justine A Ellis
    Department of Physiology, The University of Melbourne, Melbourne, Vic, 3010, Australia
    Hum Genet 121:451-7. 2007
    ..The identification of functional non-coding variants surrounding AR may have significance not only for baldness, but also for the many other complex conditions that have thus far been linked to AR...
  21. ncbi request reprint Microsomal epoxide hydrolase is not associated with COPD in a community-based sample
    Melanie C Matheson
    Department of Epidemiology and Preventive Medicine, Monash University, Victoria, Australia
    Hum Biol 78:705-17. 2006
    ..This finding, along with doubt shed on the accuracy of other studies that have demonstrated positive associations, suggests that a strong role for the EPHX1 polymorphisms in respiratory disease is unlikely...
  22. doi request reprint The role of genetics and environment in the rise of childhood food allergy
    T H T Tan
    Murdoch Children s Research Institute, The Royal Children s Hospital, Parkville, Vic, Australia
    Clin Exp Allergy 42:20-9. 2012
    ....
  23. ncbi request reprint The hypertrophic heart rat: a new normotensive model of genetic cardiac and cardiomyocyte hypertrophy
    Stephen B Harrap
    Department of Physiology, University of Melbourne, Australia
    Physiol Genomics 9:43-8. 2002
    ..The HHR offers a new model of primary cardiomyocyte hypertrophy with normal blood pressure in which to examine genotypic causes and pathogenetic mechanisms of hypertrophy and its complications...
  24. ncbi request reprint Comprehensive multi-stage linkage analyses identify a locus for adult height on chromosome 3p in a healthy Caucasian population
    Justine A Ellis
    Department of Physiology, The University of Melbourne, Melbourne, VIC 3010, Australia
    Hum Genet 121:213-22. 2007
    ..Association analyses of relevant candidate genes should identify the genetic variants responsible for the chromosome 3p linkage signal in our population...
  25. ncbi request reprint Association of IL8, CXCR2 and TNF-alpha polymorphisms and airway disease
    Melanie C Matheson
    Department of Epidemiology and Preventive Medicine, Monash University, Victoria, Australia
    J Hum Genet 51:196-203. 2006
    ..These genes may be important candidates in the modulation of the inflammatory response in the airways...
  26. ncbi request reprint Androgenic correlates of genetic variation in the gene encoding 5alpha-reductase type 1
    Justine A Ellis
    Department of Physiology, The University of Melbourne, Melbourne, Victoria, 3010, Australia
    J Hum Genet 50:534-7. 2005
    ..These results suggest that functional genetic variants might exist in or around SRD5A1 that affect the activity of the 5alpha-reductase enzyme type 1 and influence androgen levels...
  27. ncbi request reprint Androgenetic alopecia: pathogenesis and potential for therapy
    Justine A Ellis
    Department of Physiology, The University of Melbourne, Victoria 3010, Australia
    Expert Rev Mol Med 4:1-11. 2002
    ..Discovery of the involvement of the AR gene, and the identification of other genes contributing to the condition, might lead to the development of new and more effective therapies that target the condition at a more fundamental level...
  28. ncbi request reprint Tall stories: the devilish detail of genetic association studies
    Justine A Ellis
    Department of Physiology, The University of Melbourne, Victoria, Australia
    Clin Endocrinol (Oxf) 59:278-9. 2003