Research Topics
Species | Fergus CameronSummaryAffiliation: Royal Children's Hospital Country: Australia Publications
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Publications
A comparison between optimal and actuarial health care costs of adolescents with diabetesF J Cameron
Department of Endocrinology and Diabetes, Royal Children s Hospital, Melbourne, Victoria, Australia
J Paediatr Child Health 40:56-9. 2004..To assess actuarial cost and cost of optimal standards of care for adolescents with type 1 diabetes in a tertiary, hospital-based care setting. To also assess actuarial costs of diabetic adolescents in psychosocial crisis...- Assessing glycemic variation: why, when and how?Fergus J Cameron
Department of Endocrinology and Diabetes, Royal Children s Hospital, University of Melbourne, Murdoch Children s Research Institute Parkville, Melbourne, Victoria 3052, Australia
Pediatr Endocrinol Rev 7:432-44. 2010..The aim of this review is to discuss these 3 key areas: Why measure GV? When can GV be meaningfully assessed?; How to measure to GV?... - Insights into the acute cerebral metabolic changes associated with childhood diabetesF J Cameron
Centre for Hormone Research, Melbourne, Australia
Diabet Med 22:648-53. 2005.... - Does continuous glucose monitoring have clinical utility in contemporary management of diabetes?F J Cameron
Department of Endocrinology, Royal Children s Hospital, Melbourne, Victoria, Australia
J Paediatr Child Health 40:79-84. 2004..We conclude that CGMS is a useful clinical tool in the management of diabetes mellitus, provided that it is appropriately applied and the limitations are understood... - Childhood precursors of adolescent outcomes in type 1 diabetes mellitusF J Cameron
Departments of Endocrinology and Diabetes, Royal Children s Hospital, Melbourne, Australia
J Pediatr Endocrinol Metab 18:223-34. 2005..The model of care in childhood diabetes mellitus must be focussed on earlier screening and intervention if adverse outcomes are to be reduced... - Are family factors universally related to metabolic outcomes in adolescents with Type 1 diabetes?F J Cameron
Department of Endocrinology and Diabetes, Royal Children s Hospital, Melbourne, Vic, Australia
Diabet Med 25:463-8. 2008..To assess the importance of family factors in determining metabolic outcomes in adolescents with Type 1 diabetes in 19 countries... - Measuring glycaemic variationFergus J Cameron
Dept of Endocrinology and Diabetes, Royal Children s Hospital, University of Melbourne, Murdoch Children s Research Institute Parkville, Victoria, Australia
Curr Diabetes Rev 6:17-26. 2010..Investigators therefore need to be clear about the nature of their enquiry of GV and choose an appropriate metric... - Early detection of emotional and behavioural problems in children with diabetes: the validity of the Child Health Questionnaire as a screening instrumentF J Cameron
Department of Endocrinology and Diabetes, Royal Children s Hospital, Melbourne, Australia
Diabet Med 20:646-50. 2003.... - Routine psychological screening in youth with type 1 diabetes and their parents: a notion whose time has come?Fergus J Cameron
Department of Endocrinology and Diabetes, Royal Children's Hospital, Parkville, Melbourne, Victoria 3052, Australia
Diabetes Care 30:2716-24. 2007 - Teenagers with diabetes--management challengesFergus Cameron
Department of Endocrinology and Diabetes, Royal Children s Hospital, University of Melbourne, Victoria
Aust Fam Physician 35:386-90. 2006..The additional burden of living with a chronic disease such as type 1 diabetes can further add to the potential for instability... - A case-sibling assessment of the association between skin pigmentation and other vitamin D-related factors and type 1 diabetes mellitusAnne Louise Ponsonby
Murdoch Children s Research Institute, Royal Children s Hospital, Department of Paediatrics, University of Melbourne, Melbourne, Vic, Australia
Photochem Photobiol 85:1267-70. 2009..The previously demonstrated association between light skin pigmentation and T1DM risk was evident even in this comparison across sibling pairs. Further work on past UVR exposure and related factors such as skin pigmentation is required... - Reduced bone density among children with severe hemophiliaChris Barnes
Department of Haematology, Royal Children s Hospital, Flemington Rd, Melbourne, Parkville 3052, Australia
Pediatrics 114:e177-81. 2004..Children with severe hemophilia are at risk for reduced bone mineral density (BMD) because of reduced weight-bearing exercise and hepatitis C infection. Reduced bone density in childhood is a risk factor for osteoporosis in later life... - Interventions to promote optimal health outcomes in children with Type 1 diabetes--are they effective?E A Northam
Department of Psychology, University of Melbourne, Melbourne, Vic, Australia
Diabet Med 23:113-21. 2006..Attention is drawn to methodological limitations in many of the studies conducted to date and suggestions made to reduce these in future interventions attempting to reduce the burden of illness in children with diabetes... - Psychiatric morbidity and health outcome in Type 1 diabetes--perspectives from a prospective longitudinal studyE A Northam
Department of Psychology, Royal Children s Hospital, Parkville, Victoria, Australia
Diabet Med 22:152-7. 2005..To describe psychiatric status and relationship to metabolic control in adolescents with Type 1 diabetes studied prospectively from diagnosis... - Improvements in cognition, mood and behaviour following commencement of continuous subcutaneous insulin infusion therapy in children with type 1 diabetes mellitus: a pilot studyS Knight
Murdoch Children s Research Institute, Melbourne, Vic, Australia
Diabetologia 52:193-8. 2009..This study aimed to investigate changes in cognition, mood and behaviour following commencement of CSII in children with type 1 diabetes... - The impact of acute hypoglycemia on neuropsychological and neurometabolite profiles in children with type 1 diabetesDebbie Rankins
Australian Centre for Child Neuropsychological Studies, Murdoch Childrens Research Institute, Parkville, Victoria, Australia
Diabetes Care 28:2771-3. 2005 - Is bedtime supper necessary for older children with diabetes using glargine insulin in multiple daily injection regimens?A L Barton
Department of Endocrinology and Diabetes, Royal Children s Hospital, Melbourne, Australia
Diabet Med 27:238-41. 2010.... - Social consumption of alcohol in adolescents with Type 1 diabetes is associated with increased glucose lability, but not hypoglycaemiaD Ismail
Department of Endocrinology and Diabetes, Royal Children's Hospital, Melbourne, Australia
Diabet Med 23:830-3. 2006..CONCLUSIONS: In an uncontrolled, social context, moderately heavy alcohol consumption by adolescents with Type 1 diabetes appears to be associated with increased glycaemic variation, but not with low glucose levels... - Regional and urban Victorian diabetic youth: clinical and quality-of-life outcomesF J Cameron
Department of Endocrinology and Diabetes, Royal Children s Hospital, Melbourne, Australia
J Paediatr Child Health 38:593-6. 2002..To compare groups of urban and regional Victorian diabetic children and assess their quality of life, diabetes knowledge, access to services and metabolic control... - Glycaemic impact of patient-led use of sensor-guided pump therapy in type 1 diabetes: a randomised controlled trialM A O'Connell
Department of Endocrinology and Diabetes, The Royal Children s Hospital Melbourne and Murdoch Childrens Research Institute, Flemington Road, Parkville, Melbourne, Vic, 3052, Australia
Diabetologia 52:1250-7. 2009..The objective of this study was to assess the impact of patient-led sensor-guided pump management on glycaemic control, and compare the effect with that of standard insulin pump therapy... - Variation in associations between allelic variants of the vitamin D receptor gene and onset of type 1 diabetes mellitus by ambient winter ultraviolet radiation levels: a meta-regression analysisAnne Louise Ponsonby
Murdoch Childrens Research Institute, Royal Children s Hospital, Melbourne, Australia
Am J Epidemiol 168:358-65. 2008..They suggest that environmental UVR may influence the association between VDR genotype and T1DM risk. Further work on VDR polymorphisms and T1DM should concomitantly examine the roles of past UVR exposure and vitamin D status... - Reduced bone density in children on long-term warfarinChris Barnes
Department of Haematology, University of Melbourne, Royal Children's Hospital, Parkville, Australia
Pediatr Res 57:578-81. 2005..The etiology for the reduced bone density is likely to be multifactorial, however, screening of children on long-term warfarin for reduced bone density should be considered... - Twice-daily variable insulin regimens: proportions of insulin types have little impact on glycaemic control in primary school-aged childrenC M McDonnell
Department of Endocrinology and Diabetes, Royal Children s Hospital and Murdoch Childrens Research Institute, University of Melbourne, Parkville, Melbourne, Victoria, Australia
Diabet Med 25:1112-6. 2008..To ascertain the relationship between glycaemic outcome and proportions and timing of insulin admixture in a cohort of primary school-aged children who were receiving insulin in a twice-daily regimen... - Deteriorating diabetic control through adolescence-do the origins lie in childhood?P Dabadghao
Department of Endocrinology and Diabetes, Royal Children's Hospital, Parkville, Melbourne, Australia
Diabet Med 18:889-94. 2001..CONCLUSIONS: The likelihood of a significant improvement in HbA1c from late childhood to adolescence is remote, with the majority of patients having either constant or deteriorating metabolic control... - Rates of diabetes mellitus-related complications in a contemporary adolescent cohortA Kong
Centre for Hormone Research, Murdoch Children's Research Institute, Melbourne, Australia
J Pediatr Endocrinol Metab 18:247-55. 2005..Coeliac disease was diagnosed in 6% of patients. CONCLUSIONS: In this representative and contemporary cohort of diabetic adolescents the incidence of microvascular diabetes-related complications is quite low... - A novel approach to continuous glucose analysis utilizing glycemic variationC M McDonnell
Centre for Hormone Research, Royal Children's Hospital, Parkville, Melbourne, Victoria, Australia
Diabetes Technol Ther 7:253-63. 2005..Integrated use of these algorithms distinguishes between various patterns of glycemic control in those with and without diabetes... - Neonatal diabetes mellitus: Insulin pump as an alternative management strategyTara Bharucha
Centre for Hormone Research, Murdoch Children's Research Institute, Parkville, Victoria, Australia
J Paediatr Child Health 41:522-6. 2005..The latter two were successfully treated with subcutaneous insulin pump therapy. We present suggested guidelines for treatment of neonatal diabetes, using this novel approach to management... - A novel germ line mutation in SOX9 causes familial campomelic dysplasia and sex reversalF J Cameron
Department of Paediatrics, University of Melbourne, Royal Children s Hospital, Vic, Australia
Hum Mol Genet 5:1625-30. 1996..These results also demonstrate that paternal germ cell mosaicism of a mutant SOX9 sequence can result in a CD phenotype amongst his offspring... - Major increase in Type 1 diabetes: no support for the Accelerator HypothesisS Donath
Department of Endocrinology and Diabetes, Royal Children s Hospital and Murdoch Children s Research Institute, Melbourne, Australia
Diabet Med 24:920-3. 2007..The Accelerator Hypothesis predicts that this increase should be associated with younger age and increased body mass at diagnosis, with youngest children having the highest body mass index (BMI)... - Optimizing postprandial glycemia in pediatric patients with type 1 diabetes using insulin pump therapy: impact of glycemic index and prandial bolus typeMichele A O'Connell
Department of Endocrinology and Diabetes, Centre for Hormone Research, Royal Children s Hospital, Murdoch Childrens Research Institute, Melbourne, Australia
Diabetes Care 31:1491-5. 2008..We sought to compare the impact of GI combined with varying prandial bolus types on PPG... - Therapy insight: the impact of type 1 diabetes on brain development and functionElisabeth A Northam
Department of Psychology at the University of Melbourne, Melbourne, Australia
Nat Clin Pract Neurol 2:78-86. 2006..We argue that clinical management of young patients with type 1 diabetes should take into account current knowledge of the relative risks of hypoglycemia and hyperglycemia to the developing brain... - Hyperglycemia and externalizing behavior in children with type 1 diabetesCiara M McDonnell
Department of Endocrinology and Diabetes, Royal Children s Hospital, University of Melbourne, Parkville, Melbourne, Victoria, Australia
Diabetes Care 30:2211-5. 2007..Ancedotally, parents report behavioral changes in their diabetic children who have fluctuating blood glucose levels. This study aimed to test associations between intercurrent glycemia and child behavior in an ambulant setting... - Health-related quality of life and metabolic control in children with type 1 diabetes: a prospective cohort studyKylie D Hesketh
Centre for Community Child Health, Murdoch Children's Research Institute, Royal Children's Hospital, Parkville, Melbourne, Vic, Australia
Diabetes Care 27:415-20. 2004..While the HRQOL of children with diabetes does not appear to deteriorate over time, we should not be complacent, as it is consistently poorer than that of their healthy peers... - The impact of diabetes on health-related quality of life in children and adolescentsFergus J Cameron
Department of Endocrinology and Diabetes, Royal Children's Hospital, Parkville 3052, Victoria, Australia
Pediatr Diabetes 4:132-6. 2003 - Satisfaction of care in a tertiary level diabetes clinic: correlations with diabetes knowledge, clinical outcome and health-related quality of lifeIldiko H Koves
Department of Endocrinology and Diabetes, Royal Children s Hospital, Melbourne, Victoria, Australia
J Paediatr Child Health 44:432-7. 2008.... - The accuracy of clinical assessment of dehydration during diabetic ketoacidosis in childhoodIldiko H Koves
Centre for Hormone Research, Murdoch Children's Research Institute, Royal Children's Hospital Melbourne, Australia
Diabetes Care 27:2485-7. 2004 - Spontaneous recovery of steroid-induced osteopeniaTiziana G Gozzi
Department of Endocrinology and Diabetes, Royal Children's Hospital, Melbourne, Victoria, Australia
J Paediatr Child Health 42:68-9. 2006..After weaning off steroids, there was a spontaneous increase in aeral lumbar bone mineral density and also catch-up growth evident over a 5-year period... - Diabetes in adolescenceJohn M Court
Department of Endocrinology and Diabetes, Royal Children's Hospital, Parkville, Australia
Pediatr Diabetes 9:255-62. 2008 - Haemoglobin A1c: evaluation of three point of care analysers for use in a paediatric diabetes clinicRonda F Greaves
Division of Laboratory Services, The Royal Children s Hospital, Flemington Rd, Parkville, Victoria 3052, Australia
Ann Clin Biochem 42:124-9. 2005..The aim of this project was to evaluate two new HPLC instruments, the Bio-Rad D10 and the Primus PDQ, as POCT instruments compared with Bayer's DCA2000 HbA1c immunoassay analyser in our paediatric diabetes clinic... - Marked increase in type 1 diabetes mellitus incidence in children aged 0-14 yr in Victoria, Australia, from 1999 to 2002Jia W Chong
Department of Paediatrics, The University of Melbourne, Parkville, VIC 3052, Australia
Pediatr Diabetes 8:67-73. 2007..The objectives of the study were to (i) determine the incidence of type 1 diabetes mellitus (T1DM) in children aged <15 yr in Victoria, Australia, from 1999 to 2002 and (ii) to analyze trends in incidence over this period... - Diabetic ketoacidosis, hyperosmolarity and hypernatremia: are high-carbohydrate drinks worsening initial presentation?Ciara M McDonnell
Department of Endocrinology and Diabetes, Center for Hormone Research, Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, Victoria 3052, Australia
Pediatr Diabetes 6:90-4. 2005..Carbonated carbohydrate fluid intake may precipitate a more severe presentation of type 1 diabetes mellitus (T1DM). Fluid composition and intake should be carefully estimated at admission to help identify and manage similar cases... - Contemporary Australian outcomes in childhood and adolescent type 1 diabetes: 10 years post the Diabetes Control and Complications TrialGeoffrey R Ambler
Institute of Endocrinology and Diabetes, The Children s Hospital at Westmead, Westmead, and School of Women s and Children s Health, University of New South Wales, Sydney, NSW, Australia
J Paediatr Child Health 42:403-10. 2006..These data are important in planning future management strategies and resource allocation and as a basis for future research... - The paradigm of pediatric diabetes--art vs. science. Meeting Highlights - 31st Annual ISPAD Meeting, August 31- September 3, 2005, Krakow, PolandCarlo L Acerini
University of Cambridge, Cambridge, UK
Pediatr Diabetes 6:230-3. 2005 - Neonatal hypoglycemia and occipital cerebral injuryPeter M Filan
Department of Neonatal Medicine, Victorian Infant Brain Study Group, Royal Children's Hospital, Melbourne, Victoria, Australia
J Pediatr 148:552-5. 2006..The etiology of this pattern of injury is unclear; however, transient hyperinsulinism may be an independent risk factor. Magnetic resonance brain imaging can delineate the extent of brain injury and guide follow-up...