Research Topics
Species | Katie AllenSummaryAffiliation: Royal Children's Hospital Country: Australia Publications
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Detail Information
Publications
Guidelines for the use of infant formulas to treat cows milk protein allergy: an Australian consensus panel opinionAndrew S Kemp
Department of Allergy and Immunology, Children s Hospital at Westmead, Sydney, NSW, Australia
Med J Aust 188:109-12. 2008..Amino acid formula is recommended as first choice in anaphylaxis and eosinophilic oesophagitis. If treatment with the initial formula is not successful, use of an alternative formula is recommended...
Vitamin D insufficiency is associated with challenge-proven food allergy in infantsKatrina J Allen
Murdoch Childrens Research Institute, Department of Paediatrics, The University of Melbourne, Department of Allergy and Immunology, The Royal Children s Hospital, Parkville, Victoria, Australia
J Allergy Clin Immunol 131:1109-16, 1116.e1-6. 2013..Epidemiological evidence has shown that pediatric food allergy is more prevalent in regions further from the equator, suggesting that vitamin D insufficiency may play a role in this disease...
A phase I study of daily treatment with a ceramide-dominant triple lipid mixture commencing in neonatesAdrian J Lowe
Murdoch Children s Research Institute, Royal Children s Hospital, Flemington Rd, Parkville 3052, Australia
BMC Dermatol 12:3. 2012..We sort to assess the safety and compliance with daily application of a ceramide-dominant triple lipid formula (EpiCeramâ„¢) commencing in the neonatal period for the prevention of eczema...
Gastro-oesophageal reflux in children--what's the worry?Katie Allen
Department of Gastroenterology, University of Melbourne Department of Paediatrics, Melbourne, Victoria
Aust Fam Physician 41:268-72. 2012..The general practitioner has a key role to play in identifying if a child requires referral for further investigation...
The epidemiology of IgE-mediated food allergy and anaphylaxisKatrina J Allen
Murdoch Childrens Research Institute, The Royal Children s Hospital, Flemington Road, Parkville 3052, Melbourne, Victoria, Australia
Immunol Allergy Clin North Am 32:35-50. 2012....
SNP selection for genes of iron metabolism in a study of genetic modifiers of hemochromatosisClare C Constantine
The Centre for Molecular, Environmental, Genetic and Analytic MEGA Epidemiology, School of Population Health, The University of Melbourne, Melbourne, Australia
BMC Med Genet 9:18. 2008..We report our experience of selecting tag SNPs in 35 genes involved in iron metabolism in a cohort study seeking to discover genetic modifiers of hereditary hemochromatosis...
HFE Cys282Tyr homozygotes with serum ferritin concentrations below 1000 microg/L are at low risk of hemochromatosisKatrina J Allen
Murdoch Childrens Research Institute, Melbourne, Australia
Hepatology 52:925-33. 2010..These observations have implications for the management of C282Y homozygotes...
Hereditary haemochromatosis - diagnosis and managementKatie Allen
Department of Gastroenterology, Gut and Liver Research group leader, Murdoch Childrens Research Institute, and University of Melbourne Department of Paediatrics, Melbourne, Victoria
Aust Fam Physician 39:938-41. 2010..Hereditary haemochromatosis is a common inherited disorder in which excessive iron is absorbed and which, over time, may cause organ damage. Genetic predisposition leads to disease in some but not all cases...
Cell-mediated rejection results in allograft loss after liver cell transplantationKatrina J Allen
Gut and Liver Research Group, Murdoch Childrens Research Institute, Melbourne, Victoria, Australia
Liver Transpl 14:688-94. 2008..This study provides evidence that a T-cell-mediated immune mechanism could be responsible for human liver cell transplant graft loss. This finding warrants confirmation in future liver cell transplants in humans...
Stem cells for the treatment of liver diseaseK J Allen
Liver Research Group, Murdoch Childrens Research Institute, Royal Children s Hospital, Parkville, Victoria 3052, Australia
Transpl Immunol 15:99-112. 2005....
Asymptomatic individuals at genetic risk of haemochromatosis take appropriate steps to prevent disease related to iron overloadKatrina J Allen
Gut and Liver Research Group, Murdoch Children s Research Institute, Melbourne, Vic, Australia
Liver Int 28:363-9. 2008..If community screening for hereditary haemochromatosis is to be considered, compliance with preventative measures and absence of significant psychological morbidity must be demonstrated...
Liver cell transplantation leads to repopulation and functional correction in a mouse model of Wilson's diseaseKatrina J Allen
Murdoch Childrens Research Institute, University of Melbourne Department of Paediatrics, Royal Children s Hospital, Parkville, Victoria, Australia
J Gastroenterol Hepatol 19:1283-90. 2004..The present study investigated the efficacy of liver cell transplantation (LCT) to correct the tx mouse phenotype...
Iron-overload-related disease in HFE hereditary hemochromatosisKatrina J Allen
Murdoch Children s Research Institute, University of Melbourne, Melbourne, Australia
N Engl J Med 358:221-30. 2008..Diseases related to iron overload develop in some C282Y homozygotes, but the extent of the risk is controversial...
Clinical aspects of pediatric food allergy and failed oral immune toleranceKatrina J Allen
Department of Allergy and Immunology, Royal Children s Hospital, Melbourne, Australia
J Clin Gastroenterol 44:391-401. 2010..The evidence underpinning the putative rise in food allergy is discussed and potential mechanisms of disease explored. Clinical aspects of various food allergic conditions including non-IgE-mediated food allergy are outlined...
The vomiting child--what to do and when to consultKatie Allen
Department of Gastroenterology, Royal Children s Hospital, Murdoch Childrens Research Institute, and Department of Paediatrics, University of Melbourne, Victoria, Australia
Aust Fam Physician 36:684-7. 2007..Vomiting is a common, nonspecific sign of a range of childhood illnesses. It may be acute or chronic and the general practitioner has a key role in identifying whether a child needs further investigation and management...
The potential of bone marrow stem cells to correct liver dysfunction in a mouse model of Wilson's diseaseKatrina J Allen
Cell and Gene Therapy Group, Murdoch Childrens Research Institute, Department of Paediatrics, University of Melbourne, Parkville, Victoria, Australia
Cell Transplant 13:765-73. 2004..Transplantation of bone marrow cells partially corrects the metabolic phenotype in a mouse model for Wilson's disease...
4. Food allergy in childhoodKatrina J Allen
Department of Allergy and Immunology, Royal Children s Hospital, Melbourne, Victoria, Australia
Med J Aust 185:394-400. 2006..Children often develop tolerance to cows milk, egg, soy and wheat by school age, whereas allergies to nuts and shellfish are more likely to be lifelong...
Chronological changes in tissue copper, zinc and iron in the toxic milk mouse and effects of copper loadingKatrina J Allen
Liver Research Group, Murdoch Childrens Research Institute, Royal Children s Hospital, Parkville, Victoria, 3052, Australia
Biometals 19:555-64. 2006..The livers of copper-loaded tx mice had a lower zinc concentration than control tx mice, whilst the kidney had double the concentration of iron suggesting that there was increased erythrocyte hemolysis in the copper-loaded mutants...
A novel association between a SNP in CYBRD1 and serum ferritin levels in a cohort study of HFE hereditary haemochromatosisClare C Constantine
Centre for MEGA Epidemiology, School of Population Health, University of Melbourne, Carlton, Victoria, Australia
Br J Haematol 147:140-9. 2009..004). This putative genetic modifier of iron overload expression accounts for 11% (95% CI 0.4%, 22.6%) of the variance in serum ferritin levels of C282Y homozygotes...
HFE C282Y homozygotes are at increased risk of breast and colorectal cancerNicholas J Osborne
Gut and Liver, Murdoch Childrens Research Institute, Melbourne, Vic, Australia
Hepatology 51:1311-8. 2010..16; 95% CI = 0.74, 1.84), or prostate cancer (HR = 1.08; 95% CI = 0.68, 1.70). Conclusion: HFE C282Y homozygotes have twice the risk of colorectal and breast cancer compared with those individuals without the C282Y variant...
The natural history of serum iron indices for HFE C282Y homozygosity associated with hereditary hemochromatosisLyle C Gurrin
Centre for MEGA Epidemiology, School of Population Health, The University of Melbourne, Melbourne, Australia
Gastroenterology 135:1945-52. 2008..We characterized the development of elevated iron measures in C282Y homozygotes followed for 12 years...
Hereditary hemochromatosis genetic testing of at-risk children: what is the appropriate age?Martin B Delatycki
Bruce Lefroy Centre for Genetic Health Research, Murdoch Children s Research Institute, Department of Paediatrics, University of Melbourne, Victoria, Australia
Genet Test 8:98-103. 2004..In the cascade setting, genetic testing for hemochromatosis need not be offered until late teenage years...
HFE C282Y/H63D compound heterozygotes are at low risk of hemochromatosis-related morbidityLyle C Gurrin
Centre for MEGA Epidemiology, School Population Health, University of Melbourne, Victoria, Australia
Hepatology 50:94-101. 2009..Although compound heterozygotes might maintain elevated iron indices during middle age, documented iron overload-related disease is rare...
Heterozygous tx mice have an increased sensitivity to copper loading: implications for Wilson's disease carriersDaphne M Y Cheah
Murdoch Childrens Research Institute, Department of Paediatrics, University of Melbourne, Royal Children s Hospital, Parkville, Victoria, Australia
Biometals 20:751-7. 2007..Our results suggest that Wilson's disease carriers in the human population may be at increased risk of copper loading if chronically exposed to elevated copper in food or drinking water...
IgE food sensitization in infants with eczema attending a dermatology departmentDavid J Hill
Murdoch Children s Research Institute, Melbourne, Australia
J Pediatr 151:359-63. 2007....
Is caesarean delivery associated with sensitization to food allergens and IgE-mediated food allergy: a systematic reviewJennifer Koplin
Murdoch Children s Research Institute and Department of Paediatrics, The University of Melbourne, Victoria, Melbourne, Australia
Pediatr Allergy Immunol 19:682-7. 2008..Future birth cohort studies should control for the effects of mode of delivery when investigating environmental modifiers of food allergy...
Can early introduction of egg prevent egg allergy in infants? AÂ population-based studyJennifer J Koplin
Murdoch Childrens Research Institute, Parkville, Australia
J Allergy Clin Immunol 126:807-13. 2010..Infant feeding guidelines have long recommended delaying introduction of solids and allergenic foods to prevent allergy in high-risk infants, despite a paucity of evidence...
Soy consumption is not a risk factor for peanut sensitizationJennifer Koplin
Murdoch Children s Research Institute, Melbourne, Australia
J Allergy Clin Immunol 121:1455-9. 2008..A recent cohort study suggested that intake of soy milk or soy formula was associated with peanut allergy. If this finding is confirmed, it suggests an avenue for modification of diet as a peanut allergy prevention strategy...
Early clinical predictors of remission of peanut allergy in childrenMarco H K Ho
Department of Allergy and Immunology, Royal Children s Hospital, Melbourne, Australia
J Allergy Clin Immunol 121:731-6. 2008..Understanding predictors of clinical remission would assist in clinical management of peanut allergy...
Management of cow's milk protein allergy in infants and young children: an expert panel perspectiveKatrina J Allen
Murdoch Childrens Research Institute, Melbourne, Vic, Australia
J Paediatr Child Health 45:481-6. 2009....
Diagnosis and management of iron deficiency anaemia: a clinical updateSant Rayn S Pasricha
Royal Melbourne Hospital, Melbourne, Vic, Australia
Med J Aust 193:525-32. 2010..New-generation IV products, supported by high-quality evidence of safety and efficacy, may facilitate rapid administration of higher doses of iron, and may make it easier to integrate IV iron replacement into routine care...
Population genetic screening for hereditary haemochromatosis: are we a step closer?Katrina J Allen
Med J Aust 189:300-1. 2008
Screening for hemochromatosis in asymptomatic subjects with or without a family historyLawrie W Powell
Centre for the Advancement of Clinical Research, Royal Brisbane and Women s Hospital, Brisbane, Queensland 4029, Australia
Arch Intern Med 166:294-301. 2006..This study compared screening for hemochromatosis in subjects with or without a family history...
Population genetic screening for hereditary haemochromatosisDorota M Gertig
Med J Aust 179:517-8. 2003
