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Genomes and Genes | Royal Children's HospitalSummaryOrganization: Royal Children's Hospital Country: Australia Top Publications
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Children's participation in home, school and community life after acquired brain injuryJane Galvin
Paediatric Rehabilitation Service, Royal Children s Hospital, 50 Flemington Road, Parkville, Vic, 3052 Australia
Aust Occup Ther J 57:118-26. 2010..Parent ratings regarding the impact of cognitive, motor and behavioural impairments on participation were obtained. In addition, the influence of environmental factors on participation was investigated...
Allergy testing and referral in childrenMarnie Robinson
Immunology and Allergy Fellow, Royal Children s Hospital, Melbourne, Victoria
Aust Fam Physician 37:210-3. 2008..An understanding of what diagnostic tests the allergist may use in confirming the diagnosis is also necessary...
Sleep problems in children with attention-deficit/hyperactivity disorder: prevalence and the effect on the child and familyValerie Sung
Centre for Community Child Health, Royal Children s Hospital, Flemington Road, Parkville, Victoria, Australia 3052
Arch Pediatr Adolesc Med 162:336-42. 2008....
High-concentration nitrous oxide for procedural sedation in children: adverse events and depth of sedationFranz E Babl
Emergency Department, Royal Children s Hospital, Parkville, Vic 3055, Australia
Pediatrics 121:e528-32. 2008..We set out to characterize the depth of sedation and incidence of adverse events associated with various concentrations of nitrous oxide used in a pediatric emergency department...
Elevated glucose concentrations during an oral glucose tolerance test are associated with the presence of metabolic syndrome in childhood obesityM A Sabin
Clinical Sciences, The University of Bristol and Royal Hospital for Children, Bristol, UK
Diabet Med 25:289-95. 2008....
Varicella and the pregnant woman: prevention and managementAndrew J Daley
Infection Control Department, The Royal Women s Hospital and The Royal Children s Hospital, Melbourne, Australia
Aust N Z J Obstet Gynaecol 48:26-33. 2008..Clinical practice guidelines for management of a pregnant woman exposed to VZV are presented...
Iron-overload-related disease in HFE hereditary hemochromatosisKatrina J Allen
Murdoch Children s Research Institute, University of Melbourne, Melbourne, Australia
N Engl J Med 358:221-30. 2008..Diseases related to iron overload develop in some C282Y homozygotes, but the extent of the risk is controversial...
Changing cultures: enhancing mental health and wellbeing of refugee young people through education and trainingLyndal Bond
Centre for Adolescent Health, Department of Paediatrics University of Melbourne, Royal Children s Hospital, Australia
Promot Educ 14:143-9. 2007....
Community-wide screening for cystic fibrosis carriers could replace newborn screening for the diagnosis of cystic fibrosisJohn Massie
Department of Respiratory Medicine, Royal Children s Hospital, Parkville, Victoria, Australia
J Paediatr Child Health 43:721-3. 2007..Waiting for couples to have a baby with CF before they are identified as carriers denies them choice. A national policy on CF carrier screening in Australia, and determination to equitably fund such a programme, is required...
COMT Val(158)Met and 5HTTLPR functional loci interact to predict persistence of anxiety across adolescence: results from the Victorian Adolescent Health Cohort StudyC A Olsson
Centre for Adolescent Health, Murdoch Childrens Research Institute, Royal Children s Hospital, The University of Melbourne, Parkville, Victoria, Australia
Genes Brain Behav 6:647-52. 2007....
Introduction of a liaison nurse role in a tertiary paediatric ICUChelsea L Caffin
PICU Liaison Nurse, Royal Children s Hospital, Flemington Road, Parkville 3052, Australia
Intensive Crit Care Nurs 23:226-33. 2007..The role of the PICU liaison nurse (LN) has been developed to bridge the gap between PICU and the wards within the hospital with the aim of reducing the number of readmissions to the PICU within 48h of discharge...
A pilot study of inhaled methoxyflurane for procedural analgesia in childrenFranz Babl
Department of Emergency Medicine, Royal Children s Hospital and Murdoch Childrens Research Institute, Melbourne, Australia
Paediatr Anaesth 17:148-53. 2007..We conducted a pilot study to explore its use as a patient controlled analgesic for painful procedures in children in the emergency department (ED)...
Ropivacaine spinal anesthesia in neonates: a dose range finding studyGeoff Frawley
Department of Paediatric Anaesthesia and Pain Management, Royal Children s Hospital, Melbourne, Victoria, Australia
Paediatr Anaesth 17:126-32. 2007..Secondary aims were to determine the dose-response curve for spinal anesthesia including the clinically relevant ED95 dose and to describe the duration of motor block following ropivacaine spinal anesthesia...
Current management of the undescended testicleJohn M Hutson
Department of General Surgery, Royal Childrens Hospital Melbourne, Parkville, Victoria, Australia
Semin Pediatr Surg 16:64-70. 2007..Risks associated with cryptorchidism include infertility and malignancy. The aim of appropriate management is to minimize these, and any other, associated complications...
Emergency use of a size 1 laryngeal mask airway in a ventilated neonate with an undiagnosed type IV laryngotracheo-oesophageal cleftPhilip Russell
Department of Anaesthesia, Princess Margaret Hospital for Children, Perth, WA, Australia
Paediatr Anaesth 18:658-62. 2008..The emergency use of a laryngeal mask airway as a rescue maneuver allowed positive pressure ventilation, and subsequent diagnosis of the airway abnormality. The difficulties in management of the two co-existing conditions are discussed...
Mass psychogenic response to human papillomavirus vaccinationJim P Buttery
SAEFVIC, Murdoch Childrens Research Institute, Royal Children's Hospital, and Department of Paediatrics, University of Melbourne, Melbourne, Vic, Australia
Med J Aust 189:261-2. 2008
When should oxygen be given to children at high altitude? A systematic review to define altitude-specific hypoxaemiaRami Subhi
Centre for International Child Health, Department of Paediatrics, University of Melbourne, Royal Children s Hospital, Victoria, Australia
Arch Dis Child 94:6-10. 2009..This study aimed to define normal oxygen saturation and to estimate the threshold of hypoxaemia for children permanently living at different altitudes...
Evaluation of a paediatric procedural sedation training and credentialing programme: sustainability of changeFranz E Babl
University of Melbourne, Emergency Department, Royal Children s Hospital, Flemington Road, Parkville, Victoria 3052, Australia
Emerg Med J 27:577-81. 2010..The study aimed to establish whether changes in practice had been sustained 3 years after implementation of the PPS programme...
CryptorchidismJohn M Hutson
Department of Paediatrics, University of Melbourne, Melbourne, Victoria, Australia
Semin Pediatr Surg 19:215-24. 2010..Further research into the cause and management of undescended testes is necessary...
The impact of menstruation in adolescents with disabilities related to cerebral palsyMargaret Zacharin
Department of Endocrinology and Diabetes, The Royal Children s Hospital, Parkville, Melbourne, Victoria 3052, Australia
Arch Dis Child 95:526-30. 2010..Information regarding menstrual difficulties for adolescents with developmental disabilities and their families is limited...
Measuring glycaemic variationFergus J Cameron
Dept of Endocrinology and Diabetes, Royal Children s Hospital, University of Melbourne, Murdoch Children s Research Institute Parkville, Victoria, Australia
Curr Diabetes Rev 6:17-26. 2010..Investigators therefore need to be clear about the nature of their enquiry of GV and choose an appropriate metric...
Bacille Calmette-Guérin vaccine-related disease in HIV-infected children: a systematic reviewP Azzopardi
Melbourne School of Population Health, University of Melbourne, Department of Paediatrics, Royal Children s Hospital, Melbourne, Victoria, Australia
Int J Tuberc Lung Dis 13:1331-44. 2009..To describe the characteristics and risk of bacille Calmette-Guérin (BCG) vaccine related disease in human immunodeficiency virus (HIV) infected infants...
Survivors of childhood cancer: an Australian audit of vaccination status after treatmentNigel W Crawford
NHMRC Centre for Clinical Research Excellence in Child and Adolescent Immunization, Parkville, Vic, Australia
Pediatr Blood Cancer 54:128-33. 2010..The aim of this study was to describe the compliance of post-chemotherapy revaccination of childhood cancer survivors relative to current Australian guidelines...
Global emm type distribution of group A streptococci: systematic review and implications for vaccine developmentAndrew C Steer
Centre for International Child Health, University of Melbourne, Australia
Lancet Infect Dis 9:611-6. 2009....
Relative potencies of bupivacaine, levobupivacaine, and ropivacaine for neonatal spinal anaesthesiaG Frawley
Department of Paediatric Anaesthesia and Pain Management, Royal Children s Hospital, Anaesthesia Research, Murdoch Childrens Research Institute, Melbourne, Australia
Br J Anaesth 103:731-8. 2009..This information is important to compare agents and to determine the most effective spinal dose...
Probiotics and prebiotics: immunological and clinical effects in allergic diseaseMimi L K Tang
Department of Allergy and Immunology, Royal Children s Hospital, Parkville, Melbourne, Vic, Australia
Nestle Nutr Workshop Ser Pediatr Program 64:219-35; discussion 235-8, 251-7. 2009..Studies to clarify the optimal dose, bacterial species/strains, whether there is added benefit with synbiotics, the optimal timing for intervention, and the patient populations who would benefit most from such therapies are warranted...
Measuring psychosocial risk in families caring for a child with cancer: the Psychosocial Assessment Tool (PAT2.0)Maria C McCarthy
Children s Cancer Centre, Royal Children s Hospital, Melbourne, Australia
Pediatr Blood Cancer 53:78-83. 2009..0 in an Australian pediatric oncology sample. Further aims included examining mothers' and fathers' PAT2.0 scores, change in psychosocial risk over time, and the relationship between treatment intensity and psychosocial risk...
Childhood brain insult: can age at insult help us predict outcome?Vicki Anderson
Department of Psychology, Royal Children s Hospital, Flemington Road, Parkville, Victoria, Australia
Brain 132:45-56. 2009....
The non-compliance of clinical guidelines for organ donation with Australian statute lawJames Tibballs
Royal Children s Hospital, Melbourne
J Law Med 16:335-55. 2008..Simple abandonment of the "dead donor rule", however, is not feasible since organ procurement would be the direct cause of death...
Long-term outcome of disorders of sex developmentG L Warne
Department of Endocrinology and Diabetes, Royal Children s Hospital, Melbourne, Victoria, Australia
Sex Dev 2:268-77. 2008..More emphasis is also needed on strategies to prevent the development of germ cell cancers. Urological problems in both males and females with DSD have been underestimated and deserve more attention...
Outcome data from the LEAP (Live, Eat and Play) trial: a randomized controlled trial of a primary care intervention for childhood overweight/mild obesityZ McCallum
Centre for Community Child Health, The University of Melbourne, Murdoch Childrens Research Institute, Parkville, Australia
Int J Obes (Lond) 31:630-6. 2007..To reduce gain in body mass index (BMI) in overweight/mildly obese children in the primary care setting...
Slight/mild sensorineural hearing loss in childrenMelissa Wake
Centre for Community Child Health, Royal Children s Hospital, Flemington Rd, Parkville 3052, Australia
Pediatrics 118:1842-51. 2006..The goal was to determine the prevalence and effects of slight/mild bilateral sensorineural hearing loss among children in elementary school...
Immunogenicity and safety of a combination pneumococcal-meningococcal vaccine in infants: a randomized controlled trialJim P Buttery
Oxford Vaccine Group, Centre for Clinical Vaccinology and Tropical Medicine, Department of Paediatrics, University of Oxford, Churchill Hospital, Headington, Oxford, UK
JAMA 293:1751-8. 2005....
Testicular descent and cryptorchidism: the state of the art in 2004John M Hutson
F Douglas Stephens Surgical Research Laboratory, Murdoch Children s Research Institute, Royal Children s Hospital, Parkville, Victoria 3052, Australia
J Pediatr Surg 40:297-302. 2005..Recent advances include the recognition of acquired cryptorchidism of critical early postnatal germ cell development and the recommendation for surgery at 6 months of age. The authors still await long-term outcome studies...
The development of food allergy after liver transplantationRobert J Boyle
Department of Immunology, Royal Children s Hospital, Melbourne, Australia
Liver Transpl 11:326-30. 2005..In conclusion, tacrolimus treatment alone cannot account for LTAFA. Host factors such as the maturity of immune regulatory mechanisms are likely to play a critical role in the development of new food allergy after a liver transplant...
Cleft mitral valve in transposition with intact ventricular septumSamuel Menahem
Department of Cardiology, Royal Children s Hospital and Monash Medical Centre, Melbourne, Australia
Cardiol Young 14:550-2. 2004..In keeping with our current knowledge of cardiac development, our cases provide further evidence that transposition with an intact ventricular septum is the end-point of the Taussig-Bing spectrum...
Paediatric management of endocrine complications in McCune-Albright syndromeMargaret Zacharin
Department of Endocrinology and Diabetes, Royal Children s Hospital, Parkville, Victoria, Australia
J Pediatr Endocrinol Metab 18:33-41. 2005..Management issues concern long-term control of GH secretion, the impracticability of surgery in this patient and radiotherapy concerns in a young child...
Psychiatric morbidity and health outcome in Type 1 diabetes--perspectives from a prospective longitudinal studyE A Northam
Department of Psychology, Royal Children s Hospital, Parkville, Victoria, Australia
Diabet Med 22:152-7. 2005..To describe psychiatric status and relationship to metabolic control in adolescents with Type 1 diabetes studied prospectively from diagnosis...
Levobupivacaine spinal anesthesia in neonates: a dose range finding studyGeoff P Frawley
Department of Paediatric Anaesthesia and Pain Management, Royal Children s Hospital, Melbourne, Australia
Paediatr Anaesth 14:838-44. 2004..The secondary aim was to determine the minimum local analgesic dose (MLAD) defined as the median effective local anesthetic dose for spinal anesthesia in neonates...
The early childhood agenda in AustraliaFrank Oberklaid
Centre for Community Child Health, Royal Children's Hospital Melbourne, Flemington Road, Parkville, Victoria 3052, Australia
Arch Dis Child 89:830. 2004
Reduced bone density among children with severe hemophiliaChris Barnes
Department of Haematology, Royal Children s Hospital, Flemington Rd, Melbourne, Parkville 3052, Australia
Pediatrics 114:e177-81. 2004..Children with severe hemophilia are at risk for reduced bone mineral density (BMD) because of reduced weight-bearing exercise and hepatitis C infection. Reduced bone density in childhood is a risk factor for osteoporosis in later life...
Endothelin-A receptor blockade and inhaled nitric oxide in a porcine model of meconium aspiration syndromeLara S Shekerdemian
Paediatric Intensive Care Unit, Royal Children s Hospital, Parkville, Melbourne, Victoria 3052, Australia
Pediatr Res 56:353-8. 2004..Endothelin-1 levels increased with both agents. BQ-123 was found to be a highly effective pulmonary vasodilator and augmented the effects of nitric oxide in this model of acute pulmonary hypertension...
Doctors' and nurses' perceptions of interdisciplinary collaboration in the NICU, and the impact of a neonatal nurse practitioner model of practiceBeverley Copnell
Royal Children s Hospital and Murdoch Childrens Research Institute, Melbourne, Australia
J Clin Nurs 13:105-13. 2004..Some have suggested that Nurse Practitioners (NPs) may be able to improve collaboration between doctors and nurses, but this assertion does not appear to have been researched...
Oral sucrose for procedural pain in sick hospitalized infants: a randomized-controlled trialD Harrison
Department of Neonatology Royal Children s Hospital, The University of Melbourne, Victoria, Australia
J Paediatr Child Health 39:591-7. 2003..To determine the efficacy of 25% oral sucrose in the reduction of pain during a heel lance procedure in sick hospitalized infants...
Complementary use of radiological skeletal survey and bone scintigraphy in detection of bony injuries in suspected child abuseS A Mandelstam
Radiology Department, Royal Children s Hospital, Parkville, Melbourne, Australia
Arch Dis Child 88:387-90; discussion 387-90. 2003..To compare the effectiveness of radiological skeletal survey and bone scintigraphy for the detection of bony injuries in cases of suspected child abuse...
Individual, family, school, and community risk and protective factors for depressive symptoms in adolescents: a comparison of risk profiles for substance use and depressive symptomsLyndal Bond
Centre for Adolescent Health, Royal Children s Hospital, Murdoch Children s Research Institute and Department of Paediatrics, University of Melbourne, Victoria, Australia
Prev Sci 6:73-88. 2005..Patterns of associations were similar for users and nonsubstance users. The findings indicate that prevention programs targeting factors for substance use have the potential to impact on depression...
Does parents' evaluation of developmental status at school entry predict language, achievement, and quality of life 2 years later?Melissa Wake
Centre for Community Child Health, Royal Children s Hospital, University of Melbourne, Department of Paediatrics and Murdoch Childrens Research Institute, Melbourne, Australia
Ambul Pediatr 5:143-9. 2005..We studied the accuracy of the Parents' Evaluation of Developmental Status (PEDS) at school entry in predicting academic, language, and health-related quality of life (HRQoL) outcomes 2 years later...
Acute rheumatic feverJonathan R Carapetis
Centre for International Child Health, University of Melbourne Department of Paediatrics and Murdoch Children s Research Institute, Melbourne, Australia
Lancet 366:155-68. 2005..The most effective approach for control of ARF and RHD is secondary prophylaxis, which is best delivered as part of a coordinated control programme...
4. Food allergy in childhoodKatrina J Allen
Department of Allergy and Immunology, Royal Children s Hospital, Melbourne, Victoria, Australia
Med J Aust 185:394-400. 2006..Children often develop tolerance to cows milk, egg, soy and wheat by school age, whereas allergies to nuts and shellfish are more likely to be lifelong...
Alternative technique for transjugular intrahepatic portosystemic shunt in a young childS Fasulakis
Department of Radiology, Royal Children s Hospital, Parkville, Vic, Australia
Australas Radiol 50:447-50. 2006..This technique may provide an alternative to conventional transjugular intrahepatic portosystemic shunt in this group...
Australian venomous jellyfish, envenomation syndromes, toxins and therapyJames Tibballs
Australian Venom Research Unit, Department of Pharmacology, The University of Melbourne, Melbourne, Australia
Toxicon 48:830-59. 2006..Two species of Physalia are present and although one is potentially lethal, has not caused death in Australian waters. Other significant genera of jellyfish include Tamoya, Pelagia, Cyanea, Aurelia and Chyrosaora...
Perinatal and neonatal ischaemic stroke: a reviewRod W Hunt
Department of Neonatal Medicine, Royal Children's Hospital, Flemington Road, Parkville VIC 3052, Australia
Thromb Res 118:39-48. 2006
Measuring anesthesia in children using the EEGAndrew J Davidson
Department of Anaesthesia and Pain Management, Royal Children s Hospital, Parkville, Vic, Australia
Paediatr Anaesth 16:374-87. 2006..In infants their use cannot yet be supported in theory or in practice...
Congenital broncho-esophageal fistula: A case reportBarry M Linnane
Department of Respiratory Medicine, Royal Children s Hospital, Flemington Road, Parkville, VIC 3052, Melbourne, Australia
Respir Med 100:1855-7. 2006..The associated renal and limb malformations make this case unique and may add weight to the theory that the underlying insult to the developing lung is vascular in origin...
Pain assessment and procedural pain management practices in neonatal units in AustraliaDenise Harrison
Department of Neonatology, Royal Children s Hospital, Melbourne, Victoria, Australia
J Paediatr Child Health 42:6-9. 2006..To identify current pain assessment and procedural pain management practices in neonatal units in Australia...
Pulmonary atresia with ventricular septal defects and major aortopulmonary collateral arteries: unifocalization brings no long-term benefitsYves d'Udekem
Department of Cardiac Surgery, Royal Children s Hospital, Melbourne, Australia
J Thorac Cardiovasc Surg 130:1496-502. 2005..We sought to evaluate the contribution of unifocalization procedures in the management of patients with pulmonary atresia, ventricular septal defect, and major aortopulmonary collateral arteries...
Effect of a low-allergen maternal diet on colic among breastfed infants: a randomized, controlled trialDavid J Hill
Department of Allergy, Royal Children s Hospital, Melbourne, Australia
Pediatrics 116:e709-15. 2005..There is controversy regarding whether hypersensitivity to food proteins contributes to colic among breastfed infants...
Cytomegalovirus remains viable in naturally infected breast milk despite being frozen for 10 daysN Curtis
University of Melbourne, Royal Children s Hospital, Parkville, VIC 3052, Australia
Arch Dis Child Fetal Neonatal Ed 90:F529-30. 2005..The milk was stored at 0-5 degrees C in a domestic refrigerator for 48 hours or frozen for different durations at -20 degrees C. Cytomegalovirus survived in breast milk despite being frozen for 10 days at -20 degrees C...
Self-management in adolescents with chronic illness. What does it mean and how can it be achieved?Susan M Sawyer
Centre for Adolescent Health, Royal Children s Hospital, 2 Gatehouse Street, Parkville, VIC 3052
Med J Aust 183:405-9. 2005..As well as listening to parents and supporting their roles, doctors should see young people alone for part of the consultation, taking a psychosocial history and carefully maintaining confidentiality...
Weighty matters--an approach to childhood overweight in general practiceZoe McCallum
Royal Children s Hospital, and Department of Paediatrics, University of Melbourne, Victoria, Australia
Aust Fam Physician 34:745-8. 2005..Primary care is increasingly recognised as a forum in which to address this growing public health issue...
Can Australian general practitioners tackle childhood overweight/obesity? Methods and processes from the LEAP (Live, Eat and Play) randomized controlled trialZoe McCallum
Centre for Community Child Health, University of Melbourne, Murdoch Childrens Research Institute, Melbourne, Australia
J Paediatr Child Health 41:488-94. 2005..General practitioners (GPs) could make an important contribution to management of childhood overweight. However, there are no efficacy data to support this, and the feasibility of this approach is unknown...
A simple intervention to improve hospital antibiotic prescribingMichael South
Department of General Medicine, Royal Children s Hospital, Flemington Road, Parkville, Victoria 3052, Australia
Med J Aust 178:207-9. 2003..To evaluate changes in prescribing behaviour after distribution of antibiotic guidelines printed on a 9 x 6 cm laminated card suitable for clipping to a hospital identification badge...
