Sheila Anne Doggrell

Summary

Affiliation: Queensland University of Technology
Country: Australia

Publications

  1. doi request reprint Lowering LDL cholesterol with margarine containing plant stanol/sterol esters: is it still relevant in 2011?
    Sheila Anne Doggrell
    Discipline of Medical Sciences, Faculty of Science and Technology, Queensland University of Technology, Gardens Point, GPO Box 2434, Brisbane, Qld 4001, Australia
    Complement Ther Med 19:37-46. 2011
  2. doi request reprint Adherence to oral endocrine treatments in women with breast cancer: can it be improved?
    Sheila A Doggrell
    Discipline of Medical Sciences, Faculty of Science and Technology, Queensland University of Technology, GPO2343, Brisbane, QLD, 4002, Australia
    Breast Cancer Res Treat 129:299-308. 2011
  3. doi request reprint Canagliflozin - something new for type 2 diabetes, but is it safe and efficacious?
    Sheila A Doggrell
    Queensland University of Technology, School of Biomedical Sciences, Faculty of Health, GPO 2434, QLD 4002, Brisbane, Australia 61 7 3138 2015 61 7 3138 1534
    Expert Opin Pharmacother 15:437-41. 2014
  4. doi request reprint Comparative studies of how living circumstances influence medication adherence in ≥65 year olds
    Sheila A Doggrell
    Faculty of Health, Gardens Point, School of Biomedical Sciences, Queensland University of Technology QUT, Brisbane, QLD, 4001, Australia
    Int J Clin Pharm 36:30-5. 2014
  5. doi request reprint Cardiac safety concerns for domperidone, an antiemetic and prokinetic, and galactogogue medicine
    Sheila A Doggrell
    Queensland University of Technology, School of Biomedical Sciences, Faculty of Health, Brisbane, QLD4002, Australia 61 7 3138 2015 61 7 3138 1534
    Expert Opin Drug Saf 13:131-8. 2014
  6. doi request reprint Inadequate management of medicines by the older-aged living in a retirement village
    Sheila A Doggrell
    Faculty of Health, Gardens Point, School of Biomedical Sciences, Queensland University of Technology QUT, Brisbane, QLD, 4001, Australia
    Int J Clin Pharm 35:546-9. 2013
  7. doi request reprint Percutaneous coronary intervention with drug-eluting stents or coronary artery bypass surgery in subjects with type 2 diabetes
    Sheila A Doggrell
    Queensland University of Technology, School of Biomedical Sciences, Faculty of Health, Australia
    Expert Opin Pharmacother 14:1269-73. 2013
  8. doi request reprint Cardiac safety concerns for ondansetron, an antiemetic commonly used for nausea linked to cancer treatment and following anaesthesia
    Sheila A Doggrell
    Queensland University of Technology, School of Biomedical Sciences, Faculty of Health, Brisbane, QLD4001, Australia
    Expert Opin Drug Saf 12:421-31. 2013
  9. doi request reprint Bariatric surgery or medicine for type 2 diabetes?
    Sheila A Doggrell
    Queensland University of Technology, School of Biomedical Science, Faculty of Health, QLD4001, Brisbane, Australia
    Expert Opin Pharmacother 13:2249-53. 2012
  10. ncbi request reprint More light at the end of the tunnel - apixaban in atrial fibrillation
    Sheila A Doggrell
    Queensland University of Technology, School of Biomedical Sciences, Faculty of Health, Brisbane, GPO 2343, QLD 4002, Australia
    Expert Opin Investig Drugs 21:1235-9. 2012

Detail Information

Publications33

  1. doi request reprint Lowering LDL cholesterol with margarine containing plant stanol/sterol esters: is it still relevant in 2011?
    Sheila Anne Doggrell
    Discipline of Medical Sciences, Faculty of Science and Technology, Queensland University of Technology, Gardens Point, GPO Box 2434, Brisbane, Qld 4001, Australia
    Complement Ther Med 19:37-46. 2011
    ..The statins and niacin have been shown to reduce cardiovascular clinical endpoints. Except in borderline normo/hypercholesterolemia, prescription drugs should be preferred to stanol/sterol esters for lowering LDL cholesterol in 2011...
  2. doi request reprint Adherence to oral endocrine treatments in women with breast cancer: can it be improved?
    Sheila A Doggrell
    Discipline of Medical Sciences, Faculty of Science and Technology, Queensland University of Technology, GPO2343, Brisbane, QLD, 4002, Australia
    Breast Cancer Res Treat 129:299-308. 2011
    ..There are also many approaches and suggestions about how to improve adherence to the oral endocrine treatments, but none of these approaches/suggestions have been scientifically tested, and they need to be...
  3. doi request reprint Canagliflozin - something new for type 2 diabetes, but is it safe and efficacious?
    Sheila A Doggrell
    Queensland University of Technology, School of Biomedical Sciences, Faculty of Health, GPO 2434, QLD 4002, Brisbane, Australia 61 7 3138 2015 61 7 3138 1534
    Expert Opin Pharmacother 15:437-41. 2014
    ..Inhibition of the sodium-glucose cotransporter 2 (SGLT2), to promote the excretion of glucose, is a new paradigm in the treatment of type 2 diabetes...
  4. doi request reprint Comparative studies of how living circumstances influence medication adherence in ≥65 year olds
    Sheila A Doggrell
    Faculty of Health, Gardens Point, School of Biomedical Sciences, Queensland University of Technology QUT, Brisbane, QLD, 4001, Australia
    Int J Clin Pharm 36:30-5. 2014
    ..However, there has been limited attention to whether these living circumstances affect adherence to medicines in the ≥65 year olds...
  5. doi request reprint Cardiac safety concerns for domperidone, an antiemetic and prokinetic, and galactogogue medicine
    Sheila A Doggrell
    Queensland University of Technology, School of Biomedical Sciences, Faculty of Health, Brisbane, QLD4002, Australia 61 7 3138 2015 61 7 3138 1534
    Expert Opin Drug Saf 13:131-8. 2014
    ..The US Food and Drug Administration (FDA) have issued a warning about the cardiac safety of domperidone...
  6. doi request reprint Inadequate management of medicines by the older-aged living in a retirement village
    Sheila A Doggrell
    Faculty of Health, Gardens Point, School of Biomedical Sciences, Queensland University of Technology QUT, Brisbane, QLD, 4001, Australia
    Int J Clin Pharm 35:546-9. 2013
    ....
  7. doi request reprint Percutaneous coronary intervention with drug-eluting stents or coronary artery bypass surgery in subjects with type 2 diabetes
    Sheila A Doggrell
    Queensland University of Technology, School of Biomedical Sciences, Faculty of Health, Australia
    Expert Opin Pharmacother 14:1269-73. 2013
    ..Thus, if CABG is going to be preferred to PCI in subjects with type 2 diabetes and multivessel coronary disease, consideration should be given as to how to reduce the rates of stroke with CABG...
  8. doi request reprint Cardiac safety concerns for ondansetron, an antiemetic commonly used for nausea linked to cancer treatment and following anaesthesia
    Sheila A Doggrell
    Queensland University of Technology, School of Biomedical Sciences, Faculty of Health, Brisbane, QLD4001, Australia
    Expert Opin Drug Saf 12:421-31. 2013
    ....
  9. doi request reprint Bariatric surgery or medicine for type 2 diabetes?
    Sheila A Doggrell
    Queensland University of Technology, School of Biomedical Science, Faculty of Health, QLD4001, Brisbane, Australia
    Expert Opin Pharmacother 13:2249-53. 2012
    ..Larger studies, or a compilation of studies, are needed to determine whether one of these procedures is better, or if they are all similarly effective, and this should also be weighed against the risk of the operations...
  10. ncbi request reprint More light at the end of the tunnel - apixaban in atrial fibrillation
    Sheila A Doggrell
    Queensland University of Technology, School of Biomedical Sciences, Faculty of Health, Brisbane, GPO 2343, QLD 4002, Australia
    Expert Opin Investig Drugs 21:1235-9. 2012
    ....
  11. doi request reprint The ezetimibe controversy - can this be resolved by comparing the clinical trials with simvastatin and ezetimibe alone and together?
    Sheila A Doggrell
    Queensland University of Technology, School of Biomedical Sciences, Gardens Point Campus, Faculty of Health, Brisbane, GPO 2343, Qld 4001, Australia
    Expert Opin Pharmacother 13:1469-80. 2012
    ..Hypercholesterolemia plays a key role in the development and progression of atherosclerosis and can lead to cardiac heart disease...
  12. ncbi request reprint PALLAS: limiting indications for dronedarone treatment of atrial fibrillation?
    Sheila A Doggrell
    Queensland University of Technology, School of Biomedical Sciences, Faculty of Health, Brisbane, Qld 4001, Australia 61 7 3138 2015 61 7 3138 1534
    Expert Opin Pharmacother 13:867-71. 2012
    ..The mechanism(s) underlying the detrimental effects of dronedarone in permanent atrial fibrillation are unknown at present and need to be investigated...
  13. ncbi request reprint Dalcetrapib--restoring belief in modulating CETP as a beneficial mechanism in cardiovascular disease
    Sheila A Doggrell
    Queensland University of Technology, Discipline of Medical Sciences, Faculty of Science and Technology, GPO 2434, Qld 4001, Brisbane, Australia
    Expert Opin Investig Drugs 21:569-73. 2012
    ....
  14. doi request reprint Found in translation: integrated approaches to drug development
    Sheila A Doggrell
    Discipline of Medical Sciences, Faculty of Science and Technology, Queensland University of Technology, Brisbane, Qld 4001, Australia
    Expert Rev Clin Pharmacol 4:207-9. 2011
    ..The new targets included B7-dependent costimulation, chemoattractant receptors, granulocyte-macrophage colony-stimulating factor and glutathione peroxidases...
  15. ncbi request reprint Lemur tyrosine kinase-3 (LMTK3) as a target in oestrogen positive breast cancer
    Sheila A Doggrell
    Queensland University of Technology, Discipline of Medical Sciences, Faculty of Science and Technology, Brisbane, GPO 2343, Qld 4001, Australia 61 7 3138 2015 61 7 3138 1534
    Expert Opin Ther Targets 15:1419-22. 2011
    ..In nude mice, with established human MCF-7 breast cancer tumours, LMTK3 siRNA decreased tumour growth. In conclusion, LMKT3 is a possible target and marker of breast cancer...
  16. doi request reprint CX3CR1 as a target for airways inflammation
    Sheila A Doggrell
    Queensland University of Technology, Discipline of Medical Sciences, Brisbane, Australia
    Expert Opin Ther Targets 15:1139-42. 2011
    ..Subsequently, further consideration can be given to the development of CX3CR1 as a target for airway inflammation in humans...
  17. doi request reprint Sitagliptin or exenatide once weekly for type 2 diabetes: comparison of the clinical trials
    Sheila A Doggrell
    Queensland University of Technology, Discipline of Medical Sciences, Faculty of Science and Technology, Brisbane, Australia
    Expert Opin Pharmacother 12:2055-67. 2011
    ..Sitagliptin is one of the DDP-4 inhibitors used to increase the levels of GLP-1. Exenatide is an agonist at the GLP-1 receptors, which is resistant to breakdown and has a longer action than GLP-1...
  18. ncbi request reprint Bitter taste receptors as a target for bronchodilation
    Sheila A Doggrell
    Queensland University of Technology, Discipline of Medical Sciences, Faculty of Science and Technology, Brisbane, Australia
    Expert Opin Ther Targets 15:899-902. 2011
    ..Thus, it is not known whether any of these have clinical potential in asthma. It may be necessary to design and develop selective agonists for TAS2R, before the clinical potential of this target can be thoroughly investigated...
  19. ncbi request reprint New findings with old drugs for osteoporosis
    Sheila A Doggrell
    Queensland University of Technology, School of Life Sciences, GPO Box 2334, QLD4001, Australia
    Expert Opin Pharmacother 10:513-6. 2009
    ..Postmenopausal osteoporosis is common and is associated with stooped posture, loss of height, back pain and fractures...
  20. ncbi request reprint Ticagrelor, a platelet aggregation inhibitor for the potential prevention and treatment of arterial thrombosis and acute coronary syndromes
    Sheila A Doggrell
    Queensland University of Technology, School of Life Sciences, GPO Box 2434, Brisbane, QLD4001, Australia
    IDrugs 12:309-17. 2009
    ..Outcomes from an ongoing phase III trial comparing ticagrelor with clopidogrel in 18,000 patients with ACS are likely to impact on the future development of ticagrelor...
  21. doi request reprint Tesofensine--a novel potent weight loss medicine. Evaluation of: Astrup A, Breum L, Jensen TJ, Kroustrup JP, Larsen TM. Effect of tesofensine on bodyweight loss, body composition, and quality of life in obese patients: a randomised, double-blind, placebo-
    Sheila A Doggrell
    Queensland University of Technology, School of Life Sciences, GPO Box 2334, Qld 4001, Australia
    Expert Opin Investig Drugs 18:1043-6. 2009
    ..The incidence of obesity is increasing; this is of major concern, as obesity is associated with cardiovascular disease, stroke, type 2 diabetes, respiratory tract disease, and cancer...
  22. doi request reprint Clinical efficacy and safety of zoledronic acid in prostate and breast cancer
    Sheila A Doggrell
    School of Life Sciences, Queensland University of Technology, GPO Box 2334, Qld 4001, Australia
    Expert Rev Anticancer Ther 9:1211-8. 2009
    ..The efficacy and safety of zoledronic acid in osteoporosis secondary to hormone-sensitive cancers (prostate and breast), and in the bone metastases associated with these cancers are reviewed...
  23. ncbi request reprint The hedgehog pathway inhibitor GDC-0449 shows potential in skin and other cancers
    Sheila A Doggrell
    Queensland University of Technology, School of Life Sciences, Faculty of Science and Technology, GPO Box 2434, QLD4001, Brisbane, Australia 61 7 3138 2015 61 7 31381534
    Expert Opin Investig Drugs 19:451-4. 2010
    ..These clinical trials with GDC-0449, and trials with other hedgehog inhibitors, will reveal whether it is beneficial and safe to inhibit the hedgehog pathway in a wide range of solid tumours or not...
  24. ncbi request reprint New drugs for the treatment of coronary artery syndromes: otamixaban and ticagrelor
    Sheila A Doggrell
    Queensland University of Technology, School of Life Sciences, Faculty of Science and Technology, GPO Box 2343, Queensland 4001, Brisbane, Australia 61 7 3138 2015 61 7 31381534
    Expert Opin Pharmacother 11:325-9. 2010
    ..Two new drugs for acute coronary syndromes, otamixaban and ticagrelor, have recently been shown to have benefits in subjects undergoing percutaneous interventions compared to the present standard regimens for this condition...
  25. doi request reprint Adherence to medicines in the older-aged with chronic conditions: does intervention by an allied health professional help?
    Sheila A Doggrell
    School of Life Sciences, Queensland University of Technology, Brisbane, Queensland, Australia
    Drugs Aging 27:239-54. 2010
    ....
  26. ncbi request reprint Good results for early treatment of clinically isolated syndrome prior to multiple sclerosis with interferon beta-1b and glatiramer group
    Sheila A Doggrell
    Queensland University of Technology, School of Life Sciences, Faculty of Science and Technology, GPO 2343, Qld 4001, Brisbane, Australia
    Expert Opin Pharmacother 11:1225-30. 2010
    ..However, it is not known whether this early treatment slows the progression to the physical disabilities experienced in multiple sclerosis...
  27. doi request reprint Does intervention by an allied health professional discussing adherence to medicines improve this adherence in Type 2 diabetes?
    S A Doggrell
    Discipline of Medical Sciences, Faculty of Science and Technology, Queensland University of Technology, Gardens Point, GPO2434, QLD4001, Australia
    Diabet Med 27:1341-9. 2010
    ..The aim of this review was to determine whether an intervention by an allied health professional, including a discussion of adherence to medicines, improved adherence to medicines in these subjects...
  28. ncbi request reprint Are there better Bcr-Abl kinase inhibitors for chronic myeloid leukaemia than imatinib? Evaluation of Saglio G, Kim D-W, Issaragrisil S, et al. Nilotinib versus imatinib for newly diagnosed chronic myeloid leukemia. N Engl J Med 2010;362:2251-9, and Kanta
    Sheila A Doggrell
    Queensland University of Technology, Discipline of Medical Sciences, Faculty of Science and Technology, Brisbane, GPO 2343, QLD4002, Australia
    Expert Opin Pharmacother 12:157-63. 2011
    ..They should be considered as first choice in the treatment of subjects who develop CML. However, there are still major limitations to the populations with which these 'inib' drugs can be used, and how they can be used...
  29. ncbi request reprint Is there evidence to support the use of direct Factor Xa inhibitors in coronary artery disease?
    Sheila Anne Doggrell
    Discipline of Medical Sciences, Faculty of Science and Technology, Queensland University of Technology, GPO 2343, Qld 4001, Brisbane, Australia
    Rev Recent Clin Trials 6:147-57. 2011
    ..Nevertheless, apixaban and rivaroxaban are presently in placebo-controlled Phase III clinical trials for ACS. Presently, there is no compelling evidence to support the use of direct FXa inhibitors in ACS...
  30. doi request reprint A new approach to Parkinson's disease: inhibition of leucine-rich repeat kinase-2
    Sheila A Doggrell
    Queensland University of Technology, Discipline of Medical Sciences, Faculty of Science and Technology, Brisbane, Australia
    Expert Opin Investig Drugs 20:587-90. 2011
    ..Genetic studies have shown that mutations in several genes may be linked to Parkinson's disease including leucine-rich repeat kinase-2 (LRRK2). The most common of the LRRK2 mutants is the Gly2019Ser mutant...
  31. ncbi request reprint Present and future pharmacotherapy for osteoporosis
    Sheila A Doggrell
    Department of Physiology and Pharmacology, School of Biomedical Sciences, The University of Queensland, Queensland, Australia
    Drugs Today (Barc) 39:633-57. 2003
    ..New drugs/targets to promote bone formation include the commonly used lipid-lowering statins and the calcilytic release of PTH...
  32. ncbi request reprint Clopidogrel: a CURE in acute coronary syndromes?
    Sheila A Doggrell
    Department of Physiology and Pharmacology, University of Queensland, Brisbane, Queensland 4072, Australia
    Expert Opin Pharmacother 3:351-3. 2002
    ..2%, placebo 1.8%), this represented GI haemorrhages and bleeding at sites of arterial puncture rather than fatal bleeding. This trial suggests a role for clopidogrel in the long-term treatment of ACSs...