Daniel D Buchanan

Summary

Affiliation: Queensland Institute of Medical Research
Country: Australia

Publications

  1. doi request reprint Family history of colorectal cancer in BRAF p.V600E-mutated colorectal cancer cases
    Daniel D Buchanan
    Cancer and Population Studies Group, Queensland Institute of Medical Research, 300 Herston Rd, Herston QLD 4006, Australia
    Cancer Epidemiol Biomarkers Prev 22:917-26. 2013
  2. pmc Identification of BRCA1 missense substitutions that confer partial functional activity: potential moderate risk variants?
    Paul K Lovelock
    Queensland Institute of Medical Research, PO Royal Brisbane Hospital, Herston Road, Queensland 4029, Australia
    Breast Cancer Res 9:R82. 2007
  3. pmc Lessons from Lynch syndrome: a tumor biology-based approach to familial colorectal cancer
    Daniel D Buchanan
    Familial Cancer Laboratory, QIMR, Herston Q 4006, Australia
    Future Oncol 6:539-49. 2010
  4. doi request reprint Colorectal carcinomas with KRAS mutation are associated with distinctive morphological and molecular features
    Christophe Rosty
    Cancer and Population Studies Group, Queensland Institute of Medical Research, Herston, Queensland, Australia
    Mod Pathol 26:825-34. 2013
  5. pmc PIK3CA activating mutation in colorectal carcinoma: associations with molecular features and survival
    Christophe Rosty
    Cancer and Population Studies Group, Queensland Institute of Medical Research, Herston, Australia
    PLoS ONE 8:e65479. 2013
  6. pmc Analysis of families with Lynch syndrome complicated by advanced serrated neoplasia: the importance of pathology review and pedigree analysis
    Michael D Walsh
    Familial Cancer Laboratory, QIMR, Herston, QLD 4006, Australia
    Fam Cancer 8:313-23. 2009
  7. pmc Immunohistochemical testing of conventional adenomas for loss of expression of mismatch repair proteins in Lynch syndrome mutation carriers: a case series from the Australasian site of the colon cancer family registry
    Michael D Walsh
    Familial Cancer Laboratory, QIMR, Herston, QLD, Australia
    Mod Pathol 25:722-30. 2012
  8. pmc Risk factors for colorectal cancer in patients with multiple serrated polyps: a cross-sectional case series from genetics clinics
    Daniel D Buchanan
    Familial Cancer Laboratory, QIMR, Herston, Queensland, Australia
    PLoS ONE 5:e11636. 2010
  9. pmc Multiplicity and molecular heterogeneity of colorectal carcinomas in individuals with serrated polyposis
    Christophe Rosty
    Cancer and Population Studies Group, Queensland Institute of Medical Research, Bancroft Centre, Herston, QLD, Australia
    Am J Surg Pathol 37:434-42. 2013
  10. doi request reprint Lynch syndrome-associated breast cancers do not overexpress chromosome 11-encoded mucins
    Michael D Walsh
    Cancer and Population Studies Group, Queensland Institute of Medical Research, Herston, QLD 4006, Australia
    Mod Pathol 26:944-54. 2013

Collaborators

Detail Information

Publications22

  1. doi request reprint Family history of colorectal cancer in BRAF p.V600E-mutated colorectal cancer cases
    Daniel D Buchanan
    Cancer and Population Studies Group, Queensland Institute of Medical Research, 300 Herston Rd, Herston QLD 4006, Australia
    Cancer Epidemiol Biomarkers Prev 22:917-26. 2013
    ..V600E mutation are at an increased risk of CRC and extracolonic cancers (ECC). In this study, we estimated the association between a family history of either CRC or ECC and risk of CRC with a BRAF p.V600E mutation...
  2. pmc Identification of BRCA1 missense substitutions that confer partial functional activity: potential moderate risk variants?
    Paul K Lovelock
    Queensland Institute of Medical Research, PO Royal Brisbane Hospital, Herston Road, Queensland 4029, Australia
    Breast Cancer Res 9:R82. 2007
    ....
  3. pmc Lessons from Lynch syndrome: a tumor biology-based approach to familial colorectal cancer
    Daniel D Buchanan
    Familial Cancer Laboratory, QIMR, Herston Q 4006, Australia
    Future Oncol 6:539-49. 2010
    ..Finally, rare families exist in which both conditions segregate independently, producing a difficult diagnostic picture...
  4. doi request reprint Colorectal carcinomas with KRAS mutation are associated with distinctive morphological and molecular features
    Christophe Rosty
    Cancer and Population Studies Group, Queensland Institute of Medical Research, Herston, Queensland, Australia
    Mod Pathol 26:825-34. 2013
    ..In summary, KRAS-mutated carcinomas frequently develop in contiguity with a residual polyp and show molecular features distinct from other colorectal carcinomas, in particular from tumors with neither BRAF nor KRAS mutation...
  5. pmc PIK3CA activating mutation in colorectal carcinoma: associations with molecular features and survival
    Christophe Rosty
    Cancer and Population Studies Group, Queensland Institute of Medical Research, Herston, Australia
    PLoS ONE 8:e65479. 2013
    ..PIK3CA mutation also contributes to significantly decreased survival for patients with wild-type BRAF tumors...
  6. pmc Analysis of families with Lynch syndrome complicated by advanced serrated neoplasia: the importance of pathology review and pedigree analysis
    Michael D Walsh
    Familial Cancer Laboratory, QIMR, Herston, QLD 4006, Australia
    Fam Cancer 8:313-23. 2009
    ....
  7. pmc Immunohistochemical testing of conventional adenomas for loss of expression of mismatch repair proteins in Lynch syndrome mutation carriers: a case series from the Australasian site of the colon cancer family registry
    Michael D Walsh
    Familial Cancer Laboratory, QIMR, Herston, QLD, Australia
    Mod Pathol 25:722-30. 2012
    ..The overwhelming majority of conventional adenomas from mutation carriers show loss of mismatch repair protein expression concordant with the underlying germline mutation...
  8. pmc Risk factors for colorectal cancer in patients with multiple serrated polyps: a cross-sectional case series from genetics clinics
    Daniel D Buchanan
    Familial Cancer Laboratory, QIMR, Herston, Queensland, Australia
    PLoS ONE 5:e11636. 2010
    ..The aim of this work therefore was to investigate the association between smoking and the risk of CRC in high-risk genetics clinic patients presenting with multiple serrated polyps...
  9. pmc Multiplicity and molecular heterogeneity of colorectal carcinomas in individuals with serrated polyposis
    Christophe Rosty
    Cancer and Population Studies Group, Queensland Institute of Medical Research, Bancroft Centre, Herston, QLD, Australia
    Am J Surg Pathol 37:434-42. 2013
    ..The high proportion of multiple CRCs suggests that individuals with SP would benefit from frequent colonoscopic surveillance and from a consideration of a more extensive colectomy at the time of CRC diagnosis...
  10. doi request reprint Lynch syndrome-associated breast cancers do not overexpress chromosome 11-encoded mucins
    Michael D Walsh
    Cancer and Population Studies Group, Queensland Institute of Medical Research, Herston, QLD 4006, Australia
    Mod Pathol 26:944-54. 2013
    ..In addition, ectopic CDX2 expression is positively associated with de novo MUC2 expression. ..
  11. pmc A multifactorial likelihood model for MMR gene variant classification incorporating probabilities based on sequence bioinformatics and tumor characteristics: a report from the Colon Cancer Family Registry
    Bryony A Thompson
    Department of Genetics and Population Health, Queensland Institute of Medical Research, Herston, Brisbane, Australia School of Medicine, University of Queensland, Brisbane, Australia
    Hum Mutat 34:200-9. 2013
    ..Our findings provide a working multifactorial likelihood model for classification that carefully considers mode of ascertainment for gene testing...
  12. doi request reprint Mutation deep within an intron of MSH2 causes Lynch syndrome
    Mark Clendenning
    Familial Cancer Laboratory, Queensland Institute of Medical Research, 300 Herston Road, Herston, QLD, Australia
    Fam Cancer 10:297-301. 2011
    ....
  13. pmc Lynch syndrome-associated breast cancers: clinicopathologic characteristics of a case series from the colon cancer family registry
    Michael D Walsh
    Familial Cancer Laboratory, I Floor, Bancroft Centre, Queensland Institute of Medical Research, Herston Road, Herston, Queensland 4006, Australia
    Clin Cancer Res 16:2214-24. 2010
    ..The recognition of breast cancer as a spectrum tumor in Lynch syndrome remains controversial. The aim of this study was to explore features of breast cancers arising in Lynch syndrome families...
  14. pmc Linkage to chromosome 2q32.2-q33.3 in familial serrated neoplasia (Jass syndrome)
    Aedan Roberts
    Familial Cancer Laboratory, Queensland Institute of Medical Research, Herston, QLD 4006, Australia
    Fam Cancer 10:245-54. 2011
    ..36 (P = 0.004). Five primary candidate genes (CFLAR, CASP10, CASP8, FZD7 and BMPR2) were sequenced and no segregating variants identified. There was no evidence of linkage to previously reported loci on chromosomes 3, 7 and 9...
  15. doi request reprint Expression of MUC2, MUC5AC, MUC5B, and MUC6 mucins in colorectal cancers and their association with the CpG island methylator phenotype
    Michael D Walsh
    1 Cancer and Population Studies Group, Queensland Institute of Medical Research, Herston, QLD, Australia 2 Department of Histopathology, Sullivan Nicolaides Pathology, Taringa, QLD, Australia
    Mod Pathol 26:1642-56. 2013
    ..Our results suggest that, in methylator-positive tumors, mucin genes on chromosome 11p15.5 region undergo increased expression via mechanisms other than direct regulation by CDX2. ..
  16. pmc Phenotypic diversity in patients with multiple serrated polyps: a genetics clinic study
    Daniel D Buchanan
    Familial Cancer Laboratory, QIMR, Herston, Brisbane Q 4006, Australia
    Int J Colorectal Dis 25:703-12. 2010
    ..Hyperplastic polyposis is a colonic polyposis condition of unknown aetiology. The purpose of this study was to examine the spectrum of phenotypic variation in patients with multiple serrated polyps as a basis for gene discovery...
  17. doi request reprint Correlation of tumour BRAF mutations and MLH1 methylation with germline mismatch repair (MMR) gene mutation status: a literature review assessing utility of tumour features for MMR variant classification
    Michael T Parsons
    Queensland Institute of Medical Research, Herston, Brisbane, Queensland, Australia
    J Med Genet 49:151-7. 2012
    ..It is important to incorporate these features in multifactorial models aimed at predicting MMR mutation status...
  18. pmc Classifying MLH1 and MSH2 variants using bioinformatic prediction, splicing assays, segregation, and tumor characteristics
    Sven Arnold
    Genetics and Population Health Division, Queensland Institute of Medical Research, Brisbane, Australia
    Hum Mutat 30:757-70. 2009
    ..Classification of mismatch repair gene variants is assisted by a comprehensive approach that includes in vitro, tumor pathology, clinical, and evolutionary conservation data...
  19. doi request reprint Improving identification of lynch syndrome patients: a comparison of research data with clinical records
    Yen Y Tan
    School of Medicine, The University of Queensland, 288 Herston Road, Herston, Queensland 4006, Australia
    Int J Cancer 132:2876-83. 2013
    ..Hospital records indicate poor recognition of family history. Application of research methods show improved identification and may facilitate appropriate referrals of endometrial cancer patients with possible Lynch syndrome...
  20. doi request reprint Hyperplastic polyp of the duodenum: a report of 9 cases with immunohistochemical and molecular findings
    Christophe Rosty
    Anatomical Pathology, Pathology Queensland, Royal Brisbane and Women s Hospital, Herston QLD 4006, Australia
    Hum Pathol 42:1953-9. 2011
    ..However, no patient met the criteria for serrated polyposis. Although probably rare and of uncertain malignant potential, hyperplastic polyp should be considered in the differential diagnosis of benign duodenal polyp...
  21. pmc Detection of large scale 3' deletions in the PMS2 gene amongst Colon-CFR participants: have we been missing anything?
    Mark Clendenning
    Cancer and Population Studies, Queensland Institute of Medical Research, 300 Herston Road, Herston, QLD, 4006, Australia
    Fam Cancer 12:563-6. 2013
    ..No deletions encompassing any or all of exons 12 through 15 were identified; therefore, our results suggest that 3' deletions in PMS2 are not a frequent occurrence in such families...
  22. doi request reprint Molecular, pathologic, and clinical features of early-onset endometrial cancer: identifying presumptive Lynch syndrome patients
    Michael D Walsh
    Familial Cancer Laboratory and Molecular Cancer Epidemiology Laboratory, Queensland Institute of Medical Research, Herston, Australia
    Clin Cancer Res 14:1692-700. 2008
    ..The aim of this study was to determine the incidence of Lynch syndrome in a series of young-onset EC, and to identify molecular, clinical, and pathologic features that may alert clinicians to the presence of this disorder...