Beben Benyamin

Summary

Affiliation: Queensland Institute of Medical Research
Country: Australia

Publications

  1. pmc Combined genome scans for body stature in 6,602 European twins: evidence for common Caucasian loci
    Markus Perola
    Department of Molecular Medicine, National Public Health Institute, Helsinki, Finland
    PLoS Genet 3:e97. 2007
  2. pmc Common variants in TMPRSS6 are associated with iron status and erythrocyte volume
    Beben Benyamin
    Queensland Institute of Medical Research, Brisbane, Queensland, Australia
    Nat Genet 41:1173-5. 2009
  3. doi request reprint Family-based genome-wide association studies
    Beben Benyamin
    Queensland Statistical Genetics Laboratory, Queensland Institute of Medical Research, 300 Herston Road, Brisbane, QLD 4029, Australia
    Pharmacogenomics 10:181-90. 2009
  4. pmc Variants in TF and HFE explain approximately 40% of genetic variation in serum-transferrin levels
    Beben Benyamin
    Queensland Institute of Medical Research, Brisbane 4029, Australia
    Am J Hum Genet 84:60-5. 2009
  5. doi request reprint Within-family outliers: segregating alleles or environmental effects? A linkage analysis of height from 5815 sibling pairs
    Beben Benyamin
    Genetic Epidemiology, Queensland Institute of Medical Research, Brisbane, Australia
    Eur J Hum Genet 16:516-24. 2008
  6. ncbi request reprint Precision and bias of a normal finite mixture distribution model to analyze twin data when zygosity is unknown: simulations and application to IQ phenotypes on a large sample of twin pairs
    Beben Benyamin
    Institute of Evolutionary Biology, University of Edinburgh, Ashworth Laboratories, King s Buildings, West Mains Road, Edinburgh, EH9 3JT, UK
    Behav Genet 36:935-46. 2006
  7. pmc Common SNPs explain a large proportion of the heritability for human height
    Jian Yang
    Queensland Institute of Medical Research, Brisbane, Queensland, Australia
    Nat Genet 42:565-9. 2010
  8. pmc Genome partitioning of genetic variation for height from 11,214 sibling pairs
    Peter M Visscher
    Genetic Epidemiology, Queensland Institute of Medical Research, Brisbane, Australia
    Am J Hum Genet 81:1104-10. 2007
  9. pmc GWAS of butyrylcholinesterase activity identifies four novel loci, independent effects within BCHE and secondary associations with metabolic risk factors
    Beben Benyamin
    Queensland Institute of Medical Research, Brisbane 4006, Australia
    Hum Mol Genet 20:4504-14. 2011
  10. pmc The genetic aetiology of cannabis use initiation: a meta-analysis of genome-wide association studies and a SNP-based heritability estimation
    Karin J H Verweij
    Queensland Institute of Medical Research, Australia
    Addict Biol 18:846-50. 2013

Detail Information

Publications16

  1. pmc Combined genome scans for body stature in 6,602 European twins: evidence for common Caucasian loci
    Markus Perola
    Department of Molecular Medicine, National Public Health Institute, Helsinki, Finland
    PLoS Genet 3:e97. 2007
    ..To facilitate the genetic studies of stature we have also set up a website that lists all stature genome scans published and their most significant loci (http://www.genomeutwin.org/stature_gene_map.htm)...
  2. pmc Common variants in TMPRSS6 are associated with iron status and erythrocyte volume
    Beben Benyamin
    Queensland Institute of Medical Research, Brisbane, Queensland, Australia
    Nat Genet 41:1173-5. 2009
    ..1 x 10(-10)). We also find suggestive evidence of association with blood hemoglobin levels (combined P = 5.3 x 10(-7)). These findings demonstrate the involvement of TMPRSS6 in control of iron homeostasis and in normal erythropoiesis...
  3. doi request reprint Family-based genome-wide association studies
    Beben Benyamin
    Queensland Statistical Genetics Laboratory, Queensland Institute of Medical Research, 300 Herston Road, Brisbane, QLD 4029, Australia
    Pharmacogenomics 10:181-90. 2009
    ....
  4. pmc Variants in TF and HFE explain approximately 40% of genetic variation in serum-transferrin levels
    Beben Benyamin
    Queensland Institute of Medical Research, Brisbane 4029, Australia
    Am J Hum Genet 84:60-5. 2009
    ....
  5. doi request reprint Within-family outliers: segregating alleles or environmental effects? A linkage analysis of height from 5815 sibling pairs
    Beben Benyamin
    Genetic Epidemiology, Queensland Institute of Medical Research, Brisbane, Australia
    Eur J Hum Genet 16:516-24. 2008
    ..We suggest that the effect of within-family outliers deserves further investigation via theoretical and simulation studies...
  6. ncbi request reprint Precision and bias of a normal finite mixture distribution model to analyze twin data when zygosity is unknown: simulations and application to IQ phenotypes on a large sample of twin pairs
    Beben Benyamin
    Institute of Evolutionary Biology, University of Edinburgh, Ashworth Laboratories, King s Buildings, West Mains Road, Edinburgh, EH9 3JT, UK
    Behav Genet 36:935-46. 2006
    ..For the mixture distribution model, violation of the bivariate normality assumption will produce biased estimates...
  7. pmc Common SNPs explain a large proportion of the heritability for human height
    Jian Yang
    Queensland Institute of Medical Research, Brisbane, Queensland, Australia
    Nat Genet 42:565-9. 2010
    ....
  8. pmc Genome partitioning of genetic variation for height from 11,214 sibling pairs
    Peter M Visscher
    Genetic Epidemiology, Queensland Institute of Medical Research, Brisbane, Australia
    Am J Hum Genet 81:1104-10. 2007
    ....
  9. pmc GWAS of butyrylcholinesterase activity identifies four novel loci, independent effects within BCHE and secondary associations with metabolic risk factors
    Beben Benyamin
    Queensland Institute of Medical Research, Brisbane 4006, Australia
    Hum Mol Genet 20:4504-14. 2011
    ..We conclude that variation in BCHE activity is due to multiple variants across the spectrum from uncommon/large effect to common/small effect, and partly results from (rather than causes) metabolic abnormalities...
  10. pmc The genetic aetiology of cannabis use initiation: a meta-analysis of genome-wide association studies and a SNP-based heritability estimation
    Karin J H Verweij
    Queensland Institute of Medical Research, Australia
    Addict Biol 18:846-50. 2013
    ..Future genetic studies using larger sample sizes and different methodologies (including sequencing) might provide more insight in the complex genetic aetiology of cannabis use...
  11. pmc Loci affecting gamma-glutamyl transferase in adults and adolescents show age × SNP interaction and cardiometabolic disease associations
    Rita P Middelberg
    Queensland Institute of Medical Research, Brisbane, Australia
    Hum Mol Genet 21:446-55. 2012
    ..Our results reinforce the disease associations of GGT and demonstrate that control by the GGT1 locus varies with age...
  12. ncbi request reprint Large, consistent estimates of the heritability of cognitive ability in two entire populations of 11-year-old twins from Scottish mental surveys of 1932 and 1947
    Beben Benyamin
    School of Biological Sciences, University of Edinburgh, King s Buildings, West Mains Road, Edinburgh, EH9 3JT, UK
    Behav Genet 35:525-34. 2005
    ..More generally for studies in genetics, the methodological innovation developed here implies that large (national) data collections can provide sufficient information on twin pairs to estimate genetic parameters, even without zygosity...
  13. pmc Unraveling the genetic etiology of adult antisocial behavior: a genome-wide association study
    Jorim J Tielbeek
    Genetic Epidemiology, Molecular Epidemiology, and Queensland Statistical Genetics Laboratories, Queensland Institute of Medical Research, Brisbane, Queensland, Australia
    PLoS ONE 7:e45086. 2012
    ..Biosocial criminological research allows a more empirically grounded understanding of criminal behavior, which could ultimately inform and improve current treatment strategies...
  14. doi request reprint Cognitive function in adolescence: testing for interactions between breast-feeding and FADS2 polymorphisms
    Nicolas W Martin
    Queensland Institute of Medical Research, Royal Brisbane Hospital, Brisbane, QLD 4029, Australia
    J Am Acad Child Adolesc Psychiatry 50:55-62.e4. 2011
    ..An Australian sample was examined to determine if an interaction between breast-feeding and the rs174575 single nucleotide polymorphism had any effect on IQ...
  15. pmc A genome-wide association study of Cloninger's temperament scales: implications for the evolutionary genetics of personality
    Karin J H Verweij
    Genetic Epidemiology, Molecular Epidemiology, and Queensland Statistical Genetics Laboratories, Queensland Institute of Medical Research, Brisbane, Queensland, Australia
    Biol Psychol 85:306-17. 2010
    ....
  16. ncbi request reprint The use of linear mixed models to estimate variance components from data on twin pairs by maximum likelihood
    Peter M Visscher
    Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, Scotland, United Kingdom
    Twin Res 7:670-4. 2004
    ..The linear mixed model framework is particularly useful for analyzing multiple traits in extended (twin) families with a large number of random effects...