Alyson Ashe

Summary

Affiliation: Queensland Institute of Medical Research
Country: Australia

Publications

  1. pmc A genome-wide screen for modifiers of transgene variegation identifies genes with critical roles in development
    Alyson Ashe
    Epigenetics Laboratory, Queensland Institute of Medical Research, 300 Herston Road, Herston, Queensland 4006, Australia
    Genome Biol 9:R182. 2008
  2. pmc Reduced levels of two modifiers of epigenetic gene silencing, Dnmt3a and Trim28, cause increased phenotypic noise
    Nadia C Whitelaw
    Genetics and Population Health, Queensland Institute of Medical Research, 300 Herston Road, Brisbane, Queensland 4006, Australia
    Genome Biol 11:R111. 2010
  3. doi No evidence for cumulative effects in a Dnmt3b hypomorph across multiple generations
    Neil A Youngson
    Queensland Institute of Medical Research, Herston, Brisbane, QLD 4006, Australia
    Mamm Genome 24:206-17. 2013
  4. pmc A forward genetic screen identifies eukaryotic translation initiation factor 3, subunit H (eIF3h), as an enhancer of variegation in the mouse
    Lucia Daxinger
    Epigenetics Laboratory, Queensland Institute of Medical Research, Herston, Brisbane, QLD 4006, Australia
    G3 (Bethesda) 2:1393-6. 2012
  5. pmc Mutations in mouse Ift144 model the craniofacial, limb and rib defects in skeletal ciliopathies
    Alyson Ashe
    Epigenetics Laboratory, Queensland Institute for Medical Research, Herston, Queensland 4006, Australia
    Hum Mol Genet 21:1808-23. 2012

Collaborators

Detail Information

Publications5

  1. pmc A genome-wide screen for modifiers of transgene variegation identifies genes with critical roles in development
    Alyson Ashe
    Epigenetics Laboratory, Queensland Institute of Medical Research, 300 Herston Road, Herston, Queensland 4006, Australia
    Genome Biol 9:R182. 2008
    ..The identification of Dnmt1 and Smarca5 attest to the effectiveness of the screen design...
  2. pmc Reduced levels of two modifiers of epigenetic gene silencing, Dnmt3a and Trim28, cause increased phenotypic noise
    Nadia C Whitelaw
    Genetics and Population Health, Queensland Institute of Medical Research, 300 Herston Road, Brisbane, Queensland 4006, Australia
    Genome Biol 11:R111. 2010
    ..Here we show that two modifiers of epigenetic gene silencing play a critical role in the process...
  3. doi No evidence for cumulative effects in a Dnmt3b hypomorph across multiple generations
    Neil A Youngson
    Queensland Institute of Medical Research, Herston, Brisbane, QLD 4006, Australia
    Mamm Genome 24:206-17. 2013
    ..This suggests that in our model the abnormalities are reset each generation and the processes of transgenerational epigenetic reprogramming are effective in preventing their inheritance...
  4. pmc A forward genetic screen identifies eukaryotic translation initiation factor 3, subunit H (eIF3h), as an enhancer of variegation in the mouse
    Lucia Daxinger
    Epigenetics Laboratory, Queensland Institute of Medical Research, Herston, Brisbane, QLD 4006, Australia
    G3 (Bethesda) 2:1393-6. 2012
    ..Mice carrying mutations in this gene have not been reported previously, and a possible involvement of eIF3h in transcription or epigenetic regulation has not been considered...
  5. pmc Mutations in mouse Ift144 model the craniofacial, limb and rib defects in skeletal ciliopathies
    Alyson Ashe
    Epigenetics Laboratory, Queensland Institute for Medical Research, Herston, Queensland 4006, Australia
    Hum Mol Genet 21:1808-23. 2012
    ..This allelic series of mouse mutants provides a unique opportunity to uncover the underlying mechanistic basis of this intriguing subset of ciliopathies...