John Funder

Summary

Affiliation: Prince Henry's Institute of Medical Research
Country: Australia

Publications

  1. Funder J. Primary aldosteronism and salt. Pflugers Arch. 2015;467:587-94 pubmed publisher
    ..Finally, at a practical level given even the currently accepted prevalence of primary aldosteronism, a radical reconsideration of first-line antihypertensive therapy is proposed. ..
  2. Funder J, Reincke M. Aldosterone: a cardiovascular risk factor?. Biochim Biophys Acta. 2010;1802:1188-92 pubmed publisher
  3. Funder J. Reconsidering the roles of the mineralocorticoid receptor. Hypertension. 2009;53:286-90 pubmed publisher
  4. Funder J. Aldosterone and mineralocorticoid receptors in the cardiovascular system. Prog Cardiovasc Dis. 2010;52:393-400 pubmed publisher
    ..These findings on aldosterone action and mineralocorticoid receptor blockade are analyzed in the context of the prevention and treatment of cardiovascular disease. ..
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    Funder J. The role of aldosterone and mineralocorticoid receptors in cardiovascular disease. Am J Cardiovasc Drugs. 2007;7:151-7 pubmed
    ..These relatively recent insights suggest the potential therapeutic role for MR antagonists across a spectrum of cardiovascular disease, as vascular protectants even when circulating levels of aldosterone are low. ..
  6. Funder J, Mihailidou A. Aldosterone and mineralocorticoid receptors: Clinical studies and basic biology. Mol Cell Endocrinol. 2009;301:2-6 pubmed publisher
    ..This poses the question of what is activating cardiac and vascular smooth muscle MR under such circumstances, which in turn leads to a radical reconsideration of the role of glucocorticoids in non-epithelial mineralocorticoid receptors. ..
  7. Funder J. Aldosterone, sodium, and hypertension: lessons from torcetrapib?. Hypertension. 2010;55:221-3 pubmed publisher
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    Funder J. Medicine as a profession. Clin Med (Lond). 2010;10:246-7 pubmed
    ..A final consideration goes beyond the terms of the definition proposed--that of our ethical responsibility as professionals to stand up and be counted and, in the context of the disorder around us, to speak out. ..
  9. Funder J. Minireview: Aldosterone and mineralocorticoid receptors: past, present, and future. Endocrinology. 2010;151:5098-102 pubmed publisher
    ..Two decades later we still do not know the boundaries, and for every answer, two questions are springing up: truly the more we learn, the less we know. ..

More Information

Publications10

  1. Funder J. Aldosterone and mineralocorticoid receptors: a personal reflection. Mol Cell Endocrinol. 2012;350:146-50 pubmed publisher